Abstract: A sensor housing is provided that is configured to be mounted to a roof of a vehicle. The sensor housing includes a frame defining a plurality of cavities and a plurality of windows opening into respective cavities. The sensor housing also includes a plurality of sensors, at least some of which are disposed within the respective cavities defined by the frame. The sensors disposed within the respective cavities are oriented relative to the frame such that fields of view of the sensors that are disposed within the respective cavities defined by the frame are directed through the windows that open into the respective cavities. At least one of the plurality of sensors may include a camera mounted to the frame so as to be exterior to the vehicle and oriented such that a field of view of the camera is directed into a cabin of the vehicle.

Abstract: A line-type auto glass cutout tool for use with a vacuum cup device having a vacuum cup and a base connected to the vacuum cup. The tool includes a tool body with a first winding spool mounted on the tool body for rotation about a first spool axis relative to the tool body. A first drive element is coupled to the first winding spool to rotate with the first winding spool about the first spool axis. The auto glass cutout tool also includes an attachment arrangement for releasably securing the tool body to the vacuum cup device in a tool operating position.

Abstract: The invention relates to an antibody or a fragment thereof that binds specifically to the S100A4 protein for use in the prevention and/or treatment of a disease associated to pathogenic fibrosis. The invention also relates to in vitro methods for diagnosing a disease associated to pathogenic fibrosis in a subject or to in vitro methods for designing a customized therapy based on the detection of the levels of the S100A4 protein, and to the use of kits for diagnosing said diseases.

Abstract: Provided herein is a system and method for vibration mitigation at a sensor of a vehicle. Some systems include: at least one sensor; a bracket configured to support the at least one sensor; a sheet metal structure having a first major surface along which the sheet metal structure extends, and a second major surface opposite the first major surface; and a backing plate where the bracket is disposed adjacent to the first major surface of the sheet metal structure, where the backing plate is disposed adjacent to the second major surface of the sheet metal structure, and where two or more fasteners secure the backing plate to the bracket through the sheet metal structure.

Abstract: Provided herein is a system and method for a sensor housing that mitigates glare within the field-of-view and facilitates cleaning of a sensor lens. A sensor assembly may include: a sensor having a sensor lens and a field-of-view through the sensor lens; and a baffle defining a sensor lens aperture, where the field-of-view through the sensor lens is through the sensor lens aperture, where the baffle includes a series of concentric rings extending away from the sensor lens aperture and increasing in diameter as a distance from the sensor lens aperture increases. According to some embodiments, the series of concentric rings defines a viewing angle, where the viewing angle corresponds to the field-of-view of the sensor lens.

Abstract: A tether cutting system for transcatheter annuloplasty may be provided with a flexible catheter, a handle section coupled to the proximal end of the catheter having a movable actuator, and a cutter assembly coupled to the distal end of the catheter. The cutter assembly may be provided with a blade coupled to a blade holder, a slot configured to slidably receive a tether to be cut, and a backstop configured to contact the blade. The system may further include a pull wire extending through the catheter, spanning between the movable actuator and the blade holder. In one embodiment, the movable actuator, the pull wire and the blade holder are configured to cooperate together to move the blade from a distal position, across the cutter assembly slot and towards a proximal position to cut a tether extending through the slot. Methods of use are also provided.

Abstract: Disclosed herein are compounds of Formula I and methods for making the same: Also described herein are the use of such compounds, compositions for the treatment of diseases and disorders that are mediated, at least in part, by one or more cyclins, including cancer, and intermediates useful in the preparation of these compounds.

Abstract: An analog-to-digital converter (ADC) includes a first controlled oscillator (CO) for generating at least one phase signal, and wherein the at least one phase signal generates a first output signal of the ADC; and at least one first frequency-controlled resistor (FDR) for receiving the at least one phase signal generated by the first CO, wherein the first CO and the at least one first FDR are coupled together at a first subtraction node of the ADC, and wherein the first subtraction node receives a first input signal.

Abstract: The present disclosure provides at least one hemostasis valve, an introducer, and a retrieval device. The hemostasis valve may include a sealing member, a pressing assembly and a rotary motion assembly. The sealing member may be configured to define a sealing cavity which is transversely contractible. The pressing assembly is disposed at an outer periphery of the sealing member. The pressing assembly is configured for linear motion in a transverse direction of the sealing cavity to change a dimension of the sealing cavity. The rotary motion assembly is coupled to the pressing assembly, and the rotary motion assembly may be configured to convert rotary motion into the linear motion of the pressing assembly through the coupling. The hemostasis valve of the present disclosure can perform active hemostasis sealing for one or more medical devices and is convenient to use.

Abstract: The present disclosure relates to an annuloplasty device configured for being implanted via a catheter, a cinching device applied in annuloplasty, and a method of implementing annuloplasty. The annuloplasty device comprises a shaping ring and a tissue anchoring element. The shaping ring includes a first bar member, a second bar member and a third bar member that are connected via an extendable and compressible element. The first bar member, the second bar member and the third bar member are each provided with a connection portion for anchoring the shaping ring to the physiological tissue by the tissue anchoring element. An adjustment wire is provided in an inner cavity of the extendable and compressible element, for adjusting the size of the shaping ring, thereby adjusting the size of the physiological annulus.

Abstract: A locking system for transcatheter annuloplasty may be provided with an implantable lock body, a movable member configured to be slidably received in a lock body slot, a tether abutting portion, a coupling element located on a proximal portion of the lock body, a pull wire having a coupling member configured to detachable mate with the coupling element, a flexible catheter configured to slidably receive a portion of the pull wire, and a collar located on a distal portion of the catheter and configured to slidably receive the lock body. The pull wire and the catheter may be pushed together in a distal direction to advance the lock body along a tether, and the pull wire may be pulled in a proximal direction relative to the catheter to move the movable member towards a locked position and lock the tether to the lock body. Methods of use are also provided.

Abstract: A voltage-controlled oscillator analog-to-digital converter (VCO-ADC) includes a first source follower coupled between a first input terminal and a first internal node; a first VCO having an input coupled to a second internal node; a first variable resistor coupled between the first internal node and the second internal node; and a digital signal processing component coupled between an output of the first VCO and a output terminal.

Abstract: This disclosure relates to methods of surgical tissue reconstruction, such as for joint or ligament repair, and associated surgical constructs.

Abstract: An analog-to-digital converter (ADC) includes a first controlled oscillator (CO) for generating at least one phase signal, and wherein the at least one phase signal generates a first output signal of the ADC; and at least one first frequency-controlled resistor (FDR) for receiving the at least one phase signal generated by the first CO, wherein the first CO and the at least one first FDR are coupled together at a first subtraction node of the ADC, and wherein the first subtraction node receives a first input signal.

Abstract: A MicroElectroMechanical System (MEMS) includes a MEMS device; a feature extraction component coupled to an output of the MEMS device, wherein the feature extraction component is configured to provide a plurality of features of an output signal of the MEMS device; and a low data rate interface coupled to the feature extraction components, wherein the low data rate interface is configured to transmit the plurality of features of the output signal of the MEMS device, and wherein a low data rate of the low data rate interface is determined by a number of the plurality of features transmitted, wherein the MEMS device, the feature extraction component, and the low data rate interface are packaged together in a semiconductor package.

Abstract: Disclosed herein are systems and methods related to a wireless tracking system: The wireless tracking system having a plurality of beacons, each of the plurality of beacons having at least one antenna and at least one power source. When the at least one antenna is supplied with power via the power source, a local ping is transmitted from the beacon. A wireless tracking device then receives the ping via its own antenna. Once the wireless tracking device has received a locational ping from at least two of the plurality of beacons, it can then calculate a direct connection path between the at least to beacons. Based on this known path, the wireless tracking device can then determine a distance between the wireless tracking device and connection path. Based on the determined distance, the wireless tracking device may then issue a corrective measure.

Abstract: The subject invention provides pest repellent compositions and methods of using these repellent compositions for repelling pests, in particular, insect pests that are harmful for crops. Advantageously, the repellent compositions and methods of the subject invention are environmentally-friendly, non-toxic and cost-effective. Specifically, the repellent poses no harm to those insects that are beneficial for agricultural needs.

Abstract: A line-type auto glass cutout tool for use with a vacuum cup device having a vacuum cup and a base connected to the vacuum cup. The tool includes a tool body with a first winding spool mounted on the tool body for rotation about a first spool axis relative to the tool body. A first drive element is coupled to the first winding spool to rotate with the first winding spool about the first spool axis. The auto glass cutout tool also includes an attachment arrangement for releasably securing the tool body to the vacuum cup device in a tool operating position.

Abstract: A virtual containment zone system is provided. The virtual containment zone system includes a plurality of beacons, a plurality of joining segments, and a tracking device. Each of the plurality of beacons employ ultra-wideband and define a vertex of a virtual containment zone boundary that forms the perimeter of a virtual containment zone. Each of the plurality of joining segments define the virtual containment zone boundary between two of the plurality of beacons. The tracking device comprises a processing device. The processing device is configured to determine the virtual containment zone boundary, enable one or more of the plurality of joining segments to take an action in response to a location of the tracking device, determine the location of the tracking device, determine, based on the location of the tracking device, an action to take, and send, to the tracking device, a signal to perform the action.

Abstract: A voltage-controlled oscillator analog-to-digital converter (VCO-ADC) includes a first source follower coupled between a first input terminal and a first internal node; a first VCO having an input coupled to a second internal node; a first variable resistor coupled between the first internal node and the second internal node; and a digital signal processing component coupled between an output of the first VCO and a output terminal.