Patents by Inventor Luke Lee

Luke Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190146128
    Abstract: In one example, a smart mirror. The smart mirror includes a display adjacent one side of a half-mirror, sensors to acquire biometric information of a user facing an opposite side of the half-mirror, and a controller coupled to the sensors and the display. The controller determines from the biometric information a focal distance of the user. If the focal distance corresponds to the display, the controller presents a user interface on the smart mirror in a highly-visible manner and a reflection of the user in a less-visible manner. If the focal distance corresponds to the reflection of the user, the controller presents the user interface on the smart mirror in a less-visible manner and the reflection of the user in a highly-visible manner.
    Type: Application
    Filed: June 30, 2016
    Publication date: May 16, 2019
    Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
    Inventors: Zheng Cao, Dimitre Mehandjiysky, Kevin Luke Massaro, Michael Christopher Bartha, Brandon James Lee-Haist
  • Patent number: 9939430
    Abstract: The present invention relates to a method, including a diagnostic method, for characterising platelets. More particularly, the invention relates to methods for characterising platelets by immobilising platelets on a substrate for detection and subsequent characterisation, and to devices on which such a method may be practiced. The method comprises the steps of:—a. contacting a substrate that includes a plurality of discrete platelet-binding zones having a surface area of 7850 ?m2 orless with a fluid composition comprising platelets; and b. detecting platelets bound to the platelet-binding zones and thereby characterising platelets.
    Type: Grant
    Filed: October 12, 2009
    Date of Patent: April 10, 2018
    Assignees: Dublin City University, Royal College of Surgeons in Ireland
    Inventors: Lourdes Basabe-Desmonts, Sofia Ramstrom, Antonio Ricco, Kenny Dermot, Gerardene Meade, Sarah O'Neill, Asif Riaz, Luke Lee
  • Publication number: 20170144152
    Abstract: A method is provided to prepare one or more microfluidic channels on a receptive material by applying an image-forming material to a heat sensitive thermoplastic receptive material in a designed pattern and heating the material under conditions that reduce the size of the thermoplastic receptive material by at least about 60%. In an alternative aspect, the microfluidic channels on receptive material are prepared by etching a designed pattern into a heat sensitive thermoplastic material support and then heating the material under conditions that reduce the size of the thermoplastic receptive material by at least about 60%.
    Type: Application
    Filed: December 15, 2016
    Publication date: May 25, 2017
    Inventors: Michelle Khine, Chi-Shuo Chen, Anthony Grimes, David Nate Breslauer, Luke Lee, Michael Dunlap, Ajay Gopinathan, Sayantani Ghosh
  • Patent number: 9522820
    Abstract: A method is provided to prepare one or more microfluidic channels on a receptive material by applying an image-forming material to a heat sensitive thermoplastic receptive material in a designed pattern and heating the material under conditions that reduce the size of the thermoplastic receptive material by at least about 60%. In an alternative aspect, the microfluidic channels on receptive material are prepared by etching a designed pattern into a heat sensitive thermoplastic material support and then heating the material under conditions that reduce the size of the thermoplastic receptive material by at least about 60%.
    Type: Grant
    Filed: November 12, 2008
    Date of Patent: December 20, 2016
    Assignee: The Regents of the University of California
    Inventors: Michelle Khine, Chi-shuo Chen, Anthony Grimes, David Nate Breslauer, Luke Lee, Michael Dunlap, Ajay Gopinathan, Sayantani Ghosh
  • Publication number: 20150358587
    Abstract: Dissolution tester assembly that tests pharmaceutical tablets includes a frame that operatively supports a vessel having an interior into which a tablet is placed, a camera assembly supported by the frame and including a shaft having a hollow portion and an end that extends into the vessel interior, and an imaging system for imaging the tablet during the dissolution process to enable display of the images on a monitor. The imaging system includes a first camera positioned in the hollow portion of the shaft and oriented to image downward toward a bottom of the vessel, and/or a second camera positioned on the frame at a location directly below the vessel and oriented to image upward toward the bottom of the vessel. An attachment, such as a paddle for stirring or a basket for retaining the tablet, may be positioned at the end of the shaft in the vessel.
    Type: Application
    Filed: April 27, 2015
    Publication date: December 10, 2015
    Inventors: Luke Lee, Yu Sheng Zhang, Charles Cheetham
  • Patent number: 8906669
    Abstract: A sequential flow analysis tool comprising a microfluidic device having a fluid path defined within a substrate between an input and an output is described. The device includes a capture chamber provided within but offset from the fluid path, the capture chamber extending into the substrate in a direction substantially perpendicular to the fluid path such that operably particles provided within a fluid flowing within the fluid path will preferentially collect within the capture chamber.
    Type: Grant
    Filed: October 9, 2009
    Date of Patent: December 9, 2014
    Assignee: Dublin City University
    Inventors: Ivan Dimov, Jens Ducree, Luke Lee, Gregor Kijanka
  • Patent number: 8322193
    Abstract: Transdermal diffusion cell testing vessel includes a container defining a chamber having an opening against which skin is placed, and a casing arranged partially around and spaced apart from part of the container to define a compartment therebetween. The chamber retains a saline solution and is not in flow communication with the compartment through which water is circulated. The vessel includes separate inlet ports and outlet ports, each including a conduit communicating with the chamber or compartment. The outlet port of the chamber is angled downward relative to a horizontal upper surface of the container against which skin being tested is placed. The vessel is used for conducting transdermal diffusion cell testing in combination with a solution source fluidly coupled to each vessel, a waste receptacle fluidly coupled to each vessel, a syringe pump fluidly coupled to a respective vessel, and a sample collector fluidly coupled to the syringe pump(s).
    Type: Grant
    Filed: March 1, 2010
    Date of Patent: December 4, 2012
    Assignee: Logan Instruments Corp.
    Inventors: Jose Castro, Yu Sheng Zhang, Luke Lee
  • Publication number: 20120219727
    Abstract: The formation of a barrier layer within individual channels or cavities of a microfluidic device is described. The barrier layer is effected through a gas phase deposition process, desirably implemented in a plasma environment using a gas plasma reactor. Judicious selection of a precursor compound used within the gas plasma reactor can provide for generation of a layer on the individual surfaces. Desirably the surface or barrier layer is generated through the chemical adsorption of a metalloid oxide such as a silicon oxide layer on the surface of the individual channels or cavities.
    Type: Application
    Filed: June 18, 2010
    Publication date: August 30, 2012
    Applicant: Dublin City University
    Inventors: Ram Prasad Gandhiraman, Lourdes Basabe-Desmonts, Asif Riaz, Luke Lee, Ivan Dimov, Jens Ducree, Stephen Michael Daniels
  • Publication number: 20110262906
    Abstract: A sequential flow analysis tool comprising a microti iridic device having a fluid path defined within a substrate between an input and an output is described. The device includes a capture chamber provided within but offset from the fluid path, the capture chamber extending into the substrate in a direction substantially perpendicular to the fluid path such that operably particles provided within a fluid flowing within the fluid path will preferentially collect within the capture chamber.
    Type: Application
    Filed: October 9, 2009
    Publication date: October 27, 2011
    Applicant: DUBLIN CITY UNIVERSITY
    Inventors: Ivan Dimov, Jens Ducree, Luke Lee, Gregor Kijanka
  • Publication number: 20110263452
    Abstract: The present invention relates to a method, including a diagnostic method, for characterising platelets. More particularly, the invention relates to methods for characterising platelets by immobilising platelets on a substrate for detection and subsequent characterisation, and to devices on which such a method may be practiced. The method comprises the steps of:—a.contacting a substrate that includes a plurality of discrete platelet- binding zones having a surface area of 7850 ?m2 orless with a fluid composition comprising platelets; and b.detecting platelets bound to the platelet-binding zones and thereby characterising platelets.
    Type: Application
    Filed: October 12, 2009
    Publication date: October 27, 2011
    Inventors: Lourdes Basabe-Desmonts, Sofia Ramstrom, Antonio Ricco, Kenny Dermot, Gerardene Meade, Sarah O'Neill, Asif Riaz, Luke Lee
  • Publication number: 20110122406
    Abstract: A method is provided to prepare one or more microfluidic channels on a receptive material by applying an image-forming material to a heat sensitive thermoplastic receptive material in a designed pattern and heating the material under conditions that reduce the size of the thermoplastic receptive material by at least about 60%. In an alternative aspect, the microfluidic channels on receptive material are prepared by etching a designed pattern into a heat sensitive thermoplastic material support and then heating the material under conditions that reduce the size of the thermoplastic receptive material by at least about 60%.
    Type: Application
    Filed: November 12, 2008
    Publication date: May 26, 2011
    Inventors: Michelle Khine, Chi-shuo Chen, Anthoy Grimes, David Nate Breslauer, Luke Lee, Michael Dunlap, Ajay Gopinathan, Sayantani Ghosh
  • Publication number: 20110120215
    Abstract: Transdermal diffusion cell testing vessel includes a container defining a chamber having an opening against which skin is placed, and a casing arranged partially around and spaced apart from part of the container to define a compartment therebetween. The chamber retains a saline solution and is not in flow communication with the compartment through which water is circulated. The vessel includes separate inlet ports and outlet ports, each including a conduit communicating with the chamber or compartment. The outlet port of the chamber is angled downward relative to a horizontal upper surface of the container against which skin being tested is placed. The vessel is used for conducting transdermal diffusion cell testing in combination with a solution source fluidly coupled to each vessel, a waste receptacle fluidly coupled to each vessel, a syringe pump fluidly coupled to a respective vessel, and a sample collector fluidly coupled to the syringe pump(s).
    Type: Application
    Filed: March 1, 2010
    Publication date: May 26, 2011
    Applicant: LOGAN INSTRUMENTS CORP.
    Inventors: Jose Castro, Yu Sheng Zhang, Luke Lee
  • Publication number: 20110120214
    Abstract: Vessel for transdermal diffusion cell testing includes a container defining an interior chamber having an opening against which skin is placed, and a casing arranged partially around and spaced apart from part of the container to define a compartment therebetween. The chamber retains a saline solution and is not in flow communication with the compartment through which water is circulated. The vessel includes separate inlet ports and outlet ports, each including a conduit communicating with the chamber or compartment. The outlet port of the chamber is arranged above the inlet port of the chamber, proximate the opening of the chamber, and is angled downward relative to a horizontal upper surface of the container against which skin being tested is placed. Tilting of the vessel prior to or during introduction of solution prevents air bubbles from remaining between the skin and the solution.
    Type: Application
    Filed: November 23, 2009
    Publication date: May 26, 2011
    Applicant: Logan Instruments Corp.
    Inventors: Luke Lee, Yu Sheng Zhang, Jose Castro
  • Patent number: 7585465
    Abstract: Pharmaceutical product release rate testing device includes a base, at least one carousel member rotatably mounted on the base, each carousel member including a plurality of test tube pockets each adapted to receive a test tube fillable with test media, and a dipping mechanism for dipping samples to be tested into the test tubes when present in the pockets and filled with test media. A rinsing/filling mechanism is provided to rinse or fill test tubes in one set of pockets while test tubes in another set of pockets are involved in the dipping process via the dipping mechanism. The carousel member is temperature-controlled such that all of the test tubes when present in the pockets are at substantially the same temperature for critical stages of the testing process. Methods for conducting pharmaceutical product release rate testing using the device are also disclosed.
    Type: Grant
    Filed: June 15, 2006
    Date of Patent: September 8, 2009
    Assignee: Logan Instruments Corp.
    Inventors: Luke Lee, Yu Sheng Zhang, Jose Castro
  • Patent number: 7543354
    Abstract: Brush head for cleaning a vessel and use in an automatic dissolution vessel cleaning apparatus which includes a rotatable shaft defining a through passage, an upper end of which is operatively connected to a vacuum source, an inflow housing having at least one channel through which cleaning fluid is pumped and to which the shaft is rotatably mounted, and a brush assembly mounted on the shaft below the housing such that a lower end of the passage is situated below the brush assembly. In use, when the brush head is inserted into the vessel, cleaning fluid is directed through the channel(s) into the vessel while the shaft rotates causing the brush assembly to rotate and clean an inner wall of the vessel with fluid in the vessel being drawn into the passage via its lower end upon coupling of its upper end to the vacuum source.
    Type: Grant
    Filed: November 4, 2005
    Date of Patent: June 9, 2009
    Assignee: Logan Instruments Corporation
    Inventors: Luke Lee, Yu Sheng Zhang
  • Publication number: 20090138307
    Abstract: A financial scenario modeling and analysis tool, including a graphical user interface which enables a user of the tool to create a graphical model of a financial scenario, generally including at least one financial transaction, on a display screen, and an engine operable, in response to creation of the graphical model, to automatically generate information, such as financial or mathematical information, which at least partially models at least a part of the financial scenario using information collected by the engine during creation of the graphical model. The graphical user interface enables the user to create party graphics respectively representing parties to the financial deal, and to generate financial instrument graphics representing financial instruments, wherein each financial instrument graphic connects two of the party graphics.
    Type: Application
    Filed: October 8, 2008
    Publication date: May 28, 2009
    Applicant: Babcock & Brown LP, a Delaware limited partnership
    Inventors: Ladislav V. Belcsak, Luke Lee, David J. Collop, Mark R. Bewsher, Thadeus H. Niemira, Dennis D. Moritz, Stephen G. Cohn, Galen Carnicelli
  • Publication number: 20070292309
    Abstract: Pharmaceutical product release rate testing device includes a base, at least one carousel member rotatably mounted on the base, each carousel member including a plurality of test tube pockets each adapted to receive a test tube fillable with test media, and a dipping mechanism for dipping samples to be tested into the test tubes when present in the pockets and filled with test media. A rinsing/filling mechanism is provided to rinse or fill test tubes in one set of pockets while test tubes in another set of pockets are involved in the dipping process via the dipping mechanism. The carousel member is temperature-controlled such that all of the test tubes when present in the pockets are at substantially the same temperature for critical stages of the testing process. Methods for conducting pharmaceutical product release rate testing using the device are also disclosed.
    Type: Application
    Filed: June 15, 2006
    Publication date: December 20, 2007
    Inventors: Luke Lee, Yu Sheng Zhang, Jose Castro
  • Publication number: 20070155016
    Abstract: Method and systems provide improved cell handling in microfluidic systems and devices using lateral cell trapping and methods of fabrication of the same that allow for selective low voltage electroporation and electrofusion.
    Type: Application
    Filed: August 21, 2006
    Publication date: July 5, 2007
    Inventors: Luke Lee, Jeonggi Seo, Cristian Ionescu-Zanetti, Michelle Khine, Adrian Lau
  • Publication number: 20070101533
    Abstract: Brush head for cleaning a vessel and use in an automatic dissolution vessel cleaning apparatus which includes a rotatable shaft defining a through passage, an upper end of which is operatively connected to a vacuum source, an inflow housing having at least one channel through which cleaning fluid is pumped and to which the shaft is rotatably mounted, and a brush assembly mounted on the shaft below the housing such that a lower end of the passage is situated below the brush assembly. In use, when the brush head is inserted into the vessel, cleaning fluid is directed through the channel(s) into the vessel while the shaft rotates causing the brush assembly to rotate and clean an inner wall of the vessel with fluid in the vessel being drawn into the passage via its lower end upon coupling of its upper end to the vacuum source.
    Type: Application
    Filed: November 4, 2005
    Publication date: May 10, 2007
    Inventors: Luke Lee, Yu Zhang
  • Patent number: 6957191
    Abstract: A financial scenario modeling and analysis tool, including a graphical user interface which enables a user of the tool to create a graphical model of a financial scenario, generally including at least one financial transaction, on a display screen, and an engine operable, in response to creation of the graphical model, to automatically generate information, such as financial or mathematical information, which at least partially models at leat a part of the financial scenario using information collected by the engine during creation of the graphical model. The graphical user interface enables the user to create party graphics respectively representing parties to the financial deal, and to generate financial instrument graphics representing financial instruments, wherein each financial instrument graphic connects two of the party graphics.
    Type: Grant
    Filed: February 3, 2000
    Date of Patent: October 18, 2005
    Assignee: Babcock & Brown LP
    Inventors: Ladislav V. Belcsak, Luke Lee, David J. Collop, Mark R Bewsher, Thadeus H Niemira, Dennis D. Moritz, Stephen G. Cohn