Patents by Inventor Ly Tam Phan

Ly Tam Phan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 6-11 bicyclic ketolide derivatives
    Patent number: 6878691
    Abstract: The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.
    Type: Grant
    Filed: May 5, 2003
    Date of Patent: April 12, 2005
    Assignee: Enanta Pharmaceuticals, Inc.
    Inventors: Yat Sun Or, Guoqiang Wang, Ly Tam Phan, Deqiang Niu, Nha Huu Vo, Yao-Ling Qiu, Yanchun Wang, Marina Busuyek, Ying Hou, Yulin Peng, Heejin Kim, Tongzhu Liu, Jay Judson Farmer, Guoyou Xu
  • 6,11-4C-bicyclic 9a-azalide derivatives
    Publication number: 20050014707
    Abstract: The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.
    Type: Application
    Filed: May 7, 2004
    Publication date: January 20, 2005
    Inventors: Guoqiang Wang, Yat Or, Ly Tam Phan
  • 6,11-4-carbon bridged ketolides
    Patent number: 6841664
    Abstract: Novel 6,11-4-carbon bridged ketolides, pharmaceutically-acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically-acceptable carrier are described. Also described are a method for treating bacterial infections by administering to an animal a pharmaceutical composition containing a therapeutically effective amount of a compound of the invention and processes for the preparation of such compounds.
    Type: Grant
    Filed: July 25, 2002
    Date of Patent: January 11, 2005
    Assignee: Enanra Pharmaceuticals, Inc.
    Inventors: Yat Sun Or, Guoqiang Wang, Deqiang Niu, Ly Tam Phan
  • 6,11-4-Carbon bridged ketolides
    Publication number: 20040266998
    Abstract: Novel 6,11-4-carbon bridged ketolides, pharmaceutically-acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically-acceptable carrier are described. Also described are a method for treating bacterial infections by administering to an animal a pharmaceutical composition containing a therapeutically effective amount of a compound of the invention and processes for the preparation of such compounds.
    Type: Application
    Filed: May 7, 2004
    Publication date: December 30, 2004
    Inventors: Yat Sun Or, Guoqiang Wang, Deqiang Niu, Ly Tam Phan
  • 11-12 Bicyclic erythromycin derivatives
    Publication number: 20040254126
    Abstract: The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: 1
    Type: Application
    Filed: March 23, 2004
    Publication date: December 16, 2004
    Inventors: Yao-Ling Qiu, Ly Tam Phan, Zhigang Chen, Tongzhu Liu, Yat Sun Or
  • 5-O-mycaminosyltylonide derivatives
    Publication number: 20040235760
    Abstract: There are described novel 5-O-mycaminosyltylonide derivatives and pharmaceutically acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier. Also described are a method for treating bacterial infections by administering to an animal a pharmaceutical composition containing a therapeutically-effective amount of a compound of the invention, and processes for the preparation of such compounds.
    Type: Application
    Filed: March 9, 2004
    Publication date: November 25, 2004
    Inventors: Ly Tam Phan, Nha Vo, Yat Sun Or, Yao-Ling Qiu, Ying Hou
  • Novel anhydrolide derivatives having antibacterial activity
    Publication number: 20040220120
    Abstract: Novel 11-12 substituted lactone anhydrolide derivatives and pharmaceutically-acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically-acceptable carrier are described. Also described are a method for treating bacterial infections by administering to an animal a pharmaceutical composition containing a therapeutically effective amount of a compound of the invention and processes for the preparation of such compounds.
    Type: Application
    Filed: March 30, 2004
    Publication date: November 4, 2004
    Inventors: Nha Huu Vo, Ying Hou, Ly Tam Phan, Yat Sun Or
  • 11-C-substituted derivatives of clarithromycin
    Patent number: 6812216
    Abstract: There are described 11-C-substituted derivatives of clarithromycin and pharmaceutically acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier. Also described is a method for treating bacterial infections by administering to an animal a pharmaceutical composition containing a therapeutically-effective amount of a compound of the invention, and processes for the preparation of such compounds.
    Type: Grant
    Filed: June 25, 2002
    Date of Patent: November 2, 2004
    Assignee: Enanta Pharmaceuticals, Inc.
    Inventors: Ly Tam Phan, Jay Judson Farmer, Yat Sun Or
  • 11-C-substituted derivatives of clarithromycin
    Publication number: 20040209827
    Abstract: There are described 11-C-substituted derivatives of clarithromycin and pharmaceutically acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier. Also described is a method for treating bacterial infections by administering to an animal a pharmaceutical composition containing a therapeutically-effective amount of a compound of the invention, and processes for the preparation of such compounds.
    Type: Application
    Filed: May 7, 2004
    Publication date: October 21, 2004
    Inventors: Ly Tam Phan, Jay Judson Farmer, Yat Sun Or
  • Bicyclic macrolide derivatives
    Patent number: 6790835
    Abstract: The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.
    Type: Grant
    Filed: June 5, 2003
    Date of Patent: September 14, 2004
    Assignee: Enanta Pharmaceuticals, Inc.
    Inventors: Yao-Ling Qiu, Ly Tam Phan, Tongzhu Liu, Zhigang Chen, Yat Sun Or
  • Processes for the preparation of 6-11 bicyclic erythromycin derivatives
    Publication number: 20040171818
    Abstract: The present invention relates to processes and intermediates for the preparation of 6-11 bicyclic erythromycin derivatives.
    Type: Application
    Filed: January 14, 2004
    Publication date: September 2, 2004
    Inventors: Guoyou Xu, Datong Tang, Yonghua Gai, Heejin Kim, Guoqiang Wang, Ly Tam Phan, Yat Sun Or, Zhe Wang
  • 6-11 Bicyclic ketolide derivatives
    Publication number: 20040157787
    Abstract: The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: 1
    Type: Application
    Filed: November 19, 2003
    Publication date: August 12, 2004
    Inventors: Yat Sun Or, Wang Guoqiang, Ly Tam Phan, Deqiang Niu, Nha Huu Vo, Yao-Ling Qiu, Yanchun Wang, Marina Busuyek, Ying Hou, Yulin Peng, Heejin Kim, Tongzhu Liu, Jay Judson Farmer, Guoyav Xu
  • 6-O-substituted bicyclic ketolides
    Patent number: 6774115
    Abstract: The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.
    Type: Grant
    Filed: June 5, 2003
    Date of Patent: August 10, 2004
    Assignee: Enanta Pharmaceuticals, Inc.
    Inventors: Yao-Ling Qiu, Ly Tam Phan, Yat Sun Or
  • Bicyclic ketolide derivatives
    Patent number: 6765016
    Abstract: The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.
    Type: Grant
    Filed: June 5, 2003
    Date of Patent: July 20, 2004
    Assignee: Enanta Pharmaceuticals, Inc.
    Inventors: Yao-Ling Qiu, Ly Tam Phan, Zhigang Chen, Tongzhu Liu, Yat Sun Or
  • 6,11-4C-bicyclic 9a-azalide derivatives
    Patent number: 6764998
    Abstract: The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.
    Type: Grant
    Filed: June 18, 2003
    Date of Patent: July 20, 2004
    Assignee: Enanta Pharmaceuticals, Inc.
    Inventors: Guoqiang Wang, Yat Sun Or, Ly Tam Phan
  • 6,11-4-carbon bridged erythromycin derivatives
    Patent number: 6753318
    Abstract: Novel 6,11-4-carbon bridged erythromycin derivatives and pharmaceutically-acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically-acceptable carrier are described. Also described are methods for treating bacterial infections by administering to an animal a pharmaceutical composition containing a therapeutically effective amount of a compound of the invention and processes for the preparation of such compounds.
    Type: Grant
    Filed: July 25, 2002
    Date of Patent: June 22, 2004
    Assignee: Enanta Pharmaceuticals, Inc.
    Inventors: Yat Sun Or, Guoqiang Wang, Deqiang Niu, Ly Tam Phan
  • 23-O-substituted 5-O-mycaminosyltylonide derivatives
    Patent number: 6753415
    Abstract: There are described novel 5-O-mycaminosyltylonide (OMT) analogs possessing increased antibacterial activity toward Gram positive and Gram negative bacteria as well as macrolide resistant Gram positives and pharmaceutically acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: April 19, 2002
    Date of Patent: June 22, 2004
    Assignee: Enanta Pharmaceuticals, Inc.
    Inventors: Ly Tam Phan, Yao-Ling Qiu, Yat Sun Or, Nha Vo, Tianying Jian, Ying Hou, Marina Busuyek
  • 11-C-substituted ketolides
    Patent number: 6750204
    Abstract: There are described 11-C-substituted derivatives of erythromycin and pharmaceutically acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier. Also described is a method for treating bacterial infections by administering to an animal a pharmaceutical composition containing a therapeutically-effective amount of a compound of the invention, and processes for the preparation of such compounds.
    Type: Grant
    Filed: June 25, 2002
    Date of Patent: June 15, 2004
    Assignee: Enanta Pharmaceuticals, Inc.
    Inventors: Ly Tam Phan, Jay Judson Farmer, Yat Sun Or
  • 11,12-substituted lactone ketolide derivatives having antibacterial activity
    Patent number: 6727229
    Abstract: Novel 11-12 substituted lactone ketolide derivatives and pharmaceutically-acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically-acceptable carrier are described. Also described are a method for treating bacterial infections by administering to an animal a pharmaceutical composition containing a therapeutically effective amount of a compound of the invention and processes for the preparation of such compounds.
    Type: Grant
    Filed: August 19, 2002
    Date of Patent: April 27, 2004
    Assignee: Enanta Pharmaceuticals, Inc.
    Inventors: Nha Huu Vo, Ly Tam Phan, Ying Hou, Tongzhu Liu, Yat Sun Or
  • Anhydrolide derivatives having antibacterial activity
    Patent number: 6720308
    Abstract: Novel 11-12 substituted lactone anhydrolide derivatives and pharmaceutically-acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically-acceptable carrier are described. Also described are a method for treating bacterial infections by administering to an animal a pharmaceutical composition containing a therapeutically effective amount of a compound of the invention and processes for the preparation of such compounds.
    Type: Grant
    Filed: November 7, 2002
    Date of Patent: April 13, 2004
    Assignee: Enanta Pharmaceuticals, Inc.
    Inventors: Nha Huu Vo, Ying Hou, Ly Tam Phan, Yat Sun Or