Patents by Inventor Ly Tam Phan

Ly Tam Phan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 6-O-substituted bicyclic macrolides
    Patent number: 6716820
    Abstract: The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.
    Type: Grant
    Filed: June 5, 2003
    Date of Patent: April 6, 2004
    Assignee: Enanta Pharmaceuticals, Inc.
    Inventors: Yao-Ling Qiu, Ly Tam Phan, Yat Sun Or
  • 5-O-mycaminosyltylonide derivatives
    Patent number: 6710034
    Abstract: There are described novel 5-O-mycaminosyltylonide derivatives and pharmaceutically acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier. Also described are a method for treating bacterial infections by administering to an animal a pharmaceutical composition containing a therapeutically-effective amount of a compound of the invention, and processes for the preparation of such compounds.
    Type: Grant
    Filed: April 19, 2002
    Date of Patent: March 23, 2004
    Assignee: Enanta Pharmaceuticals, Inc.
    Inventors: Ly Tam Phan, Nha Vo, Yat Sun Or, Yao-Ling Qiu, Ying Hou
  • 6,11-Bicyclic erythromycin derivatives
    Publication number: 20040053861
    Abstract: The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: 1
    Type: Application
    Filed: May 13, 2003
    Publication date: March 18, 2004
    Inventors: Yat Sun Or, Guoqiang Wang, Ly Tam Phan, Deqiang Niu, Yao-Ling Qiu, Nha Huu Vo, Jay Judson Farmer, Ying Hou
  • NOVEL 11,12-SUBSTITUTED LACTONE KETOLIDE DERIVATIVES HAVING ANTIBACTERIAL ACTIVITY
    Publication number: 20040038915
    Abstract: Novel 11-12 substituted lactone ketolide derivatives and pharmaceutically-acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically-acceptable carrier are described. Also described are a method for treating bacterial infections by administering to an animal a pharmaceutical composition containing a therapeutically effective amount of a compound of the invention and processes for the preparation of such compounds.
    Type: Application
    Filed: August 19, 2002
    Publication date: February 26, 2004
    Inventors: Nha Huu Vo, Ly Tam Phan, Ying Hou, Tongzhu Liu, Yat Sun Or
  • 6,11-4-carbon bridged ketolides
    Publication number: 20040023895
    Abstract: Novel 6,11-4-carbon bridged ketolides, pharmaceutically-acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically-acceptable carrier are described. Also described are a method for treating bacterial infections by administering to an animal a pharmaceutical composition containing a therapeutically effective amount of a compound of the invention and processes for the preparation of such compounds.
    Type: Application
    Filed: July 25, 2002
    Publication date: February 5, 2004
    Inventors: Yat Sun Or, Guoqiang Wang, Deqiang Niu, Ly Tam Phan
  • 4'-substituted leucomycins
    Patent number: 6680299
    Abstract: There are described novel 4′ substituted 16-membered macrolides and pharmaceutically acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier. Also described are a method for treating bacterial infections by administering to a mammal a pharmaceutical composition containing a therapeutically-effective amount of a compound of the invention, and processes for the preparation of such compounds.
    Type: Grant
    Filed: July 27, 2001
    Date of Patent: January 20, 2004
    Assignee: Enanta Pharmaceuticals, Inc.
    Inventors: Yat Sun Or, Ly Tam Phan, Zhaolin Wang, Tianying Jian
  • 11-C-substituted derivatives of clarithromycin
    Publication number: 20040006027
    Abstract: There are described 11-C-substituted derivatives of clarithromycin and pharmaceutically acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier. Also described is a method for treating bacterial infections by administering to an animal a pharmaceutical composition containing a therapeutically-effective amount of a compound of the invention, and processes for the preparation of such compounds.
    Type: Application
    Filed: June 25, 2002
    Publication date: January 8, 2004
    Inventors: Ly Tam Phan, Jay Judson Farmer, Yat Sun Or
  • 11-O-substituted macrolides and their descladinose derivatives
    Patent number: 6673774
    Abstract: There are described 11-O-substituted macrolides and their descladinose derivatives and pharmaceutically acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier. Also described is a method for treating bacterial infections by administering to a mammal a pharmaceutical composition containing a therapeutically-effective amount of a compound of the invention, and processes for the preparation of such compounds.
    Type: Grant
    Filed: December 3, 2001
    Date of Patent: January 6, 2004
    Assignee: Enanta Pharmaceuticals, Inc.
    Inventors: Ly Tam Phan Phan, Deqiang Niu, Yat Sun Or
  • 11-C-substituted ketolides
    Publication number: 20040002464
    Abstract: There are described 11-C-substituted derivatives of erythromycin and pharmaceutically acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier. Also described is a method for treating bacterial infections by administering to an animal a pharmaceutical composition containing a therapeutically-effective amount of a compound of the invention, and processes for the preparation of such compounds.
    Type: Application
    Filed: June 25, 2002
    Publication date: January 1, 2004
    Applicant: ENANTA PHARMACEUTICALS, INC., a CORPORATION
    Inventors: Ly Tam Phan, Jay Judson Farmer, Yat Sun Or
  • 11-O-substituted ketolide derivatives
    Patent number: 6670331
    Abstract: There are described novel 11-O-substituted ketolide derivatives of clarithromycin analogs and pharmaceutically acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier. Also described is a method for treating bacterial infections by administering to a mammal a pharmaceutical composition containing a therapeutically-effective amount of a compound of the invention, and processes for the preparation of such compounds.
    Type: Grant
    Filed: December 4, 2001
    Date of Patent: December 30, 2003
    Assignee: Enanta Pharmaceuticals, Inc.
    Inventors: Ly Tam Phan Phan, Deqiang Niu, Yat Sun Or
  • 9-amino erythromycin derivatives with antibacterial activity
    Patent number: 6667338
    Abstract: Compounds of formula (I) and formula (II) or therapeutically acceptable salts or prodrugs thereof are useful as antibacterial agents. Methods to make the compounds, compositions containing the compounds, and methods of treatment using the compounds are also disclosed.
    Type: Grant
    Filed: January 16, 2002
    Date of Patent: December 23, 2003
    Assignee: Abbott Laboratories
    Inventors: Zhenkun Ma, Ly Tam Phan, Suoming Zhang, Stevan W. Djuric
  • Tylosin derivatives having antibacterial activity
    Patent number: 6664240
    Abstract: There are described novel substituted tylosin analogs and pharmaceutically acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier. Also described is a method for treating bacterial infections by administering to a mammal a pharmaceutical composition containing a therapeutically-effective amount of a compound of the invention, and processes for the preparation of such compounds.
    Type: Grant
    Filed: November 15, 2001
    Date of Patent: December 16, 2003
    Assignee: Enanta Pharmaceuticals, Inc.
    Inventors: Ly Tam Phan, Marina V. Busuyek, Yat Sun Or
  • 23-O-substituted 5-O-mycaminosyltylonide derivatives
    Publication number: 20030212010
    Abstract: There are described novel 5-O-mycaminosyltylonide (OMT) analogs possessing increased antibacterial activity toward Gram positive and Gram negative bacteria as well as macrolide resistant Gram positives and pharmaceutically acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier.
    Type: Application
    Filed: April 19, 2002
    Publication date: November 13, 2003
    Inventors: Ly Tam Phan, Yao-Ling Qiu, Yat Sun Or, Nha Vo, Tianying Jian, Ying Hou, Marina Busuyek
  • 6,11-3C-bicyclic 9a-azalide derivatives
    Patent number: 6645941
    Abstract: The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.
    Type: Grant
    Filed: March 26, 2003
    Date of Patent: November 11, 2003
    Assignee: Enanta Pharmaceuticals, Inc.
    Inventors: Guoqiang Wang, Yat Sun Or, Ly Tam Phan, Marina Busuyek
  • 5-O-mycaminosyltylonide derivatives
    Publication number: 20030203858
    Abstract: There are described novel 5-O-mycaminosyltylonide derivatives and pharmaceutically acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier. Also described are a method for treating bacterial infections by administering to an animal a pharmaceutical composition containing a therapeutically-effective amount of a compound of the invention, and processes for the preparation of such compounds.
    Type: Application
    Filed: April 19, 2002
    Publication date: October 30, 2003
    Inventors: Ly Tam Phan, Nha Vo, Yat Sun Or, Yao-Ling Qiu, Ying Hou
  • Novel 11-O-substituted ketolide derivatives
    Publication number: 20030114395
    Abstract: There are described novel 11-O-substituted ketolide derivatives of clarithromycin analogs and pharmaceutically acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier. Also described is a method for treating bacterial infections by administering to a mammal a pharmaceutical composition containing a therapeutically-effective amount of a compound of the invention, and processes for the preparation of such compounds.
    Type: Application
    Filed: December 4, 2001
    Publication date: June 19, 2003
    Inventors: Ly Tam Phan, Deqiang Niu, Yat Sun Or
  • 11-O-substituted macrolides and their descladinose derivatives
    Publication number: 20030114396
    Abstract: There are described 11-O-substituted macrolides and their descladinose derivatives and pharmaceutically acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier. Also described is a method for treating bacterial infections by administering to a mammal a pharmaceutical composition containing a therapeutically-effective amount of a compound of the invention, and processes for the preparation of such compounds.
    Type: Application
    Filed: December 3, 2001
    Publication date: June 19, 2003
    Inventors: Ly Tam Phan Phan, Deqiang Niu, Yat Sun Or
  • 4?-O-substituted tylosin analogs
    Patent number: 6576615
    Abstract: There are described novel 4′ substituted tylosin analogs and pharmaceutically acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier. Also described is a method for treating bacterial infections by administering to a mammal a pharmaceutical composition containing a therapeutically-effective amount of a compound of the invention, and processes for the preparation of such compounds.
    Type: Grant
    Filed: November 8, 2001
    Date of Patent: June 10, 2003
    Assignee: Enanta Pharmaceuticals, Inc.
    Inventors: Ly Tam Phan, Tianying Jian, Yao-Ling Qiu, Yat Sun Or
  • 6-O-alkyl-2-nor-2-substituted ketolide derivatives
    Patent number: 6569836
    Abstract: The present invention relates to 6-O-alkyl-2-nor-2-substituted ketolide compound or a derivative thereof, a composition comprising the compound and a suitable carrier, a method of preparing the compound, and a method of treatment and prevention of in mammals comprising administering said compound.
    Type: Grant
    Filed: November 30, 2000
    Date of Patent: May 27, 2003
    Assignee: Abbott Laboratories
    Inventors: Ly Tam Phan, Yat Sun Or, Zhenkun Ma
  • Novel Tylosin derivatives having antibacterial activity
    Publication number: 20030096764
    Abstract: There are described novel substituted tylosin analogs and pharmaceutically acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier. Also described is a method for treating bacterial infections by administering to a mammal a pharmaceutical composition containing a therapeutically-effective amount of a compound of the invention, and processes for the preparation of such compounds.
    Type: Application
    Filed: November 15, 2001
    Publication date: May 22, 2003
    Inventors: Ly Tam Phan, Marina V. Busuyek, Yat Sun Or