Abstract: Human EEF2K genes are identified as modulators of the PTEN/AKT pathway and thus are therapeutic targets for disorders associated with defective PTEN/AKT function. Methods for identifying modulators of PTEN/AKT comprising screening for agents that modulate the activity of EEF2K are provided.

Abstract: A line driver for generating 10 BT signals is disclosed. Digital symbols to be transmitted via a 10 BT Ethernet line are converted by a digital-to-analog converter into a corresponding analog voltage signal, which is fed into an active output impedance line driver. The digital-to-analog converter also receives a reference voltage reflecting variations of the supply voltage and adjusts its output signal accordingly to provide a deliberately variable analog voltage signal to the line driver.

Abstract: A method for obtaining an image by MRI, comprising: administering at least one contrast agent to a subject in amounts effective to perform CEDST MRI analysis; and performing CEDST MRI analysis to produce an image of the subject. A number of different contrast agents can be used to practice the present method including, without limitation, sugars, amino acids, nitrogen-containing heterocycles, purines and pyrimidines, nucleosides; imidazole and derivatives thereof, imino acids, barbituric acid and analogs thereof, and miscellaneous materials, such as guanidine hydantoin, parabanic acid, and biologically active salts thereof.

Abstract: A referral-tracking system accepts listings from originators and generates referral identifiers that represent referrals of those listings. A referral identifier represents a referral by the originator or by someone who, after receiving a listing identifier from an originator or someone else, applies to the system to be recognized as a referrer and has accordingly been issued a referral identifier that associates that requester with a listing to be referred. An originator or other requester applying for a referral identifier is given the option of identifying intended recipients to tracking system or not. If the requester does supply the tracking system with that information, the issued referral identifier is associated not only with the listings and the referring requester but also with the recipient. In that way, the system can provide conversion-rate information without discouraging participation by potential requesters who prefer not to divulge the recipients' identities.

Abstract: A method, computer system, and program product for estimating savings realized in an enterprise. Data is input into a computer reflecting the dividing of the enterprise into sections Also input the computer is data reflecting the dividing of each section into one or more functions and recording the money spent for each function over a specified period of time. Also input into the computer is data recording the maturity of each function based on standardized criteria and percent improvement data for evaluating savings to be realized as the function improves from one maturity level to a higher maturity level. The computer estimates savings to be realized for each function as the function matures from one maturity level to a higher maturity level and consolidates savings to be realized for all functions in a section and all sections in tile enterprise.

Abstract: Method for determining in vivo concentration of a metabolite that includes administering a contrast agent to a subject, allowing the contrast agent to disperse to tissue of interest, performing CEDST MRI analysis of the subject, and comparing the results to known in vitro results to determine metabolite concentration.

Abstract: An electrochemical sensor for organic molecules such as ethylene includes an electrochemical cell, gas sample inlet means and means for detecting current produced by the oxidation of the organic molecule at the anode of the cell. The sensor is capable of sensing multiple organic molecules in some embodiments. A voltage is applied to the anode of the cell to provide energy to drive the oxidation reaction and produce a corresponding current. The sensor of the invention can be made as a small, hand-held unit that is capable of real-time detection of various organic species.

Abstract: A high efficiency class-AB amplifier is disclosed. The amplifier comprises a first input stage and a second input stage, both coupled to a class-AB biasing mesh and an output stage, wherein the outputs of the first and second input stages are directly coupled to the output transistors in the output stage. In one embodiment, a first gate of the first input stage and of the second input stage are coupled together to receive the same input and a second gate of the first input stage and of the second input stage are coupled together to receive the same input. In another embodiment, the first input stage and second input stage may further comprise cascode transistors for coupling the two input stages to the class-AB biasing mesh. In yet another embodiment, a 3V supply is used and 1V transistors are used to improve gain and 3V transistors are used to protect the 1V transistors.

Abstract: A line driver for generating 10 BT signals is disclosed. Digital symbols to be transmitted via a 10 BT Ethernet line are converted by a digital-to-analog converter into a corresponding analog voltage signal, which is fed into an active output impedance line driver. The digital-to-analog converter also receives a reference voltage reflecting variations of the supply voltage and adjusts its output signal accordingly to provide a deliberately variable analog voltage signal to the line driver.

Abstract: Systems, methods and apparatus are disclosed to manage offshore software development. An example method disclosed herein includes electronically accessing offshore tool hardware and executing a compliance test on the offshore tool hardware, the compliance test returning a result. The example method further includes comparing the result of the compliance test with an offshore security policy to determine a compliance status of the offshore tool hardware.

Abstract: Systems, methods and apparatus are disclosed to manage offshore software development. An example method disclosed herein includes receiving a list of offshore resources for a project, the offshore resources accessible via an offshore module. The example method further includes receiving export laws associated with the project, determining offshore project requirements for the project based on the received export laws, the offshore project requirements compliant with the identified export laws, and communicating the offshore project requirements via the offshore module.

Abstract: An integrated side-entry sub with grease injection flow tubes is adapted for making up in a drill string and includes a port to receive a cable, such as a wire line. A first pedestal, mounted within a cutout of the side entry sub, provides entry for the cable into the entry port. The first pedestal receives a first flow tube, which couples to a lower connector manifold. The lower connector manifold further provides a grease injection port. A second flow tube, coupled to the lower connector manifold, runs to an upper connector manifold. The upper connector manifold further provides an grease return port, as well an the entry point for cable into the sub.

Abstract: Method of producing an article comprising providing a raw material in the form of a plurality of polymer elements, the polymer elements comprising an amorphous polymer; heating the materials to a temperature above a first predetermined temperature; and compacting the material whilst above the first predetermined temperature. The first predetermined temperature is the Tg of the polymer elements, the pressure is between 100 and 200 psi; and the temperature and pressure of compaction are sufficient to soften the outer portion of the polymer elements and to cause the polymer elements to bonds to each other without melting or softening of the inner portion of polymer elements. A product is produced having a structure which comprises cores of amorphous polymer that have not been softened or melted in the method, surrounded by a mass of softened and re-hardened material which bonds the cores together.

Abstract: This invention relates to newly identified Staphylococcal polynucleotides, polypeptides encoded by such polynucleotides, the uses of such polynucleotides and polypeptides, as well as the production of such polynucleotides and polypeptides and recombinant host cells transformed with the polynucleotides. This invention also relates to inhibiting the biosynthesis or action of such polynucleotides or polypeptides and to the use of such inhibitors in therapy.

Abstract: A cableless power lift assembly for raising and lowering the roof structure or camper top of a pop-up camper includes an elongated drive housing mounted to the base of a pop-up camper and a pair of aligned left and right threaded screw drives mounted in the drive housing for rotatable movement therein. A motor is attached to the left and right screw drives for rotatably driving the screw drives to raise the camper top upon actuation of said motor in a first direction and lower the camper top upon actuation of the motor in an opposite second direction. In addition, collapsible lifting apparatus is also provided for moving the camper top between a generally horizontal lowered or collapsed position and a generally horizontal raised or extended position. In a preferred embodiment, an air conditioning unit is mounted in the camper top.

Abstract: An integrated receiver with channel selection and image rejection substantially implemented on a single CMOS integrated circuit is described. A receiver front end provides programable attenuation and a programable gain low noise amplifier. Frequency conversion circuitry advantageously uses LC filters integrated onto the substrate in conjunction with image reject mixers to provide sufficient image frequency rejection. Filter tuning and inductor Q compensation over temperature are performed on chip. The filters utilize multi track spiral inductors. The filters are tuned using local oscillators to tune a substitute filter, and frequency scaling during filter component values to those of the filter being tuned. In conjunction with filtering, frequency planning provides additional image rejection. The advantageous choice of local oscillator signal generation methods on chip is by PLL out of band local oscillation and by direct synthesis for in band local oscillator.

Abstract: An oil burning lamp has a fuel reservoir, a fuel expansion chamber releasably and sealingly coupled to the fuel reservoir, a burner assembly coupled to the fuel expansion chamber, and an adjustable wick. If the fuel in the fuel reservoir undergoes thermal expansion, it flows into the fuel expansion chamber, thereby preventing fuel leaks and spills. In the preferred embodiment, the burner assembly is permanently coupled to the fuel expansion chamber, thereby preventing users from refueling the lamp while the lamp is burning. The fuel expansion chamber also serves as an overflow fuel chamber, so that if the lamp is inadvertently knocked over, the fuel will flow into the fuel expansion chamber, not out of the lamp.

Abstract: The invention provides compositions for use as pet litters and pet bedding, or for absorption of liquids and gases. These compositions are formed as aggregates or agglomerates of different components having different hydration capacities and hydration rates.

Abstract: An axial/radial—or radial/flow catalytic reactor has inlet and outlet ports and a bed of particulate catalyst disposed as e.g. a cylinder or cone round a central region communicating with one of the ports. For at least part of the height of the catalyst bed, the exterior surface of the catalyst bed has a diameter less than that of the reactor thus leaving space between the exterior surface of the catalyst bed and the interior walls of the reactor. This space is filled with a particulate material presenting less resistance to flow than the catalyst particles.