Patents by Inventor Makoto Nakanishi
Makoto Nakanishi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240259666Abstract: A mobile work analysis device is used for work analysis based on a work moving image of a line work while recording the work moving image. The mobile work analysis device includes: a first boundary setting unit configured to receive input of a user operation and set a boundary for each work element on the work moving image; a boundary detector configured to detect recognition information associated with each work process, a boundary between a work of a first work process and a work of a second work process in the line work being recognized by the recognition information; and a second boundary setting unit configured to, when the recognition information associated with the second work process is detected, automatically set the boundary on the work moving image between the work of the first work process and the work of the second work process, based on the recognition information.Type: ApplicationFiled: May 27, 2022Publication date: August 1, 2024Applicant: BROADLEAF CO., LTD.Inventors: Hiroaki NAKANISHI, Takahide ARAO, Makoto NOMURA, Takeo SHIMOYAMA
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Publication number: 20220119768Abstract: Solutions to the problem of the invention are a method for selectively killing or removing a senescent cell, substance identification, and a method for purifying a senescent cell. Specifically, the invention includes an agent for removing a senescent cell, which is a drug for removing an in vivo senescent cell, the agent containing an inhibitor for glutaminase as an active ingredient, and a pharmaceutical composition containing the agent. The invention further includes a method for preparing a senescent cell, including the following steps (a) to (c): (a) synchronizing a cell with the G2 phase; (b) activating an intracellular p53 protein in the cell synchronized with the G2 phase; and (c) inhibiting polo-like kinase 1 (PLK1) activity in the cell treated in the step (b).Type: ApplicationFiled: November 7, 2019Publication date: April 21, 2022Applicant: The University of TokyoInventors: Makoto NAKANISHI, Yoshikazu JOHMURA
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Publication number: 20220120753Abstract: The present invention is intended to provide a method for determining the prognosis of a hormone receptor-positive cancer (for example, an ER?-positive breast cancer, an ER?-positive endometrial cancer, etc.) or a method for assisting the determination of the prognosis, and a method for evaluating the sensitivity of the cancer to antihormone therapy or a method for assisting the evaluation of the sensitivity of the cancer to antihormone therapy. Specifically, the present invention relates to a method for determining the prognosis of a hormone receptor-positive cancer, or a method for assisting the determination of the prognosis, which comprises the following steps (a) and (b): (a) a step of detecting Fbxo22-positive cancer cells in a sample derived from the cancer tissues; and (b) a step of calculating the percentage of the Fbxo22-positive cancer cells to the cells present in the sample.Type: ApplicationFiled: September 20, 2019Publication date: April 21, 2022Applicants: The University of Tokyo, St. Marianna University School of MedicineInventors: Makoto NAKANISHI, Yoshikazu JOHMURA, Tomohiko OHTA
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Publication number: 20210138064Abstract: Disclosed is a vaccine for non-human animals, which vaccine enables effective immune induction in non-human animals such as livestock or poultry. The vaccine for non-human animals of the present invention comprises liposomes each comprising an antigen molecule(s) bound to the surface thereof, the antigen molecule(s) being derived from a pathogen infectious to the non-human animals. The non-human animals are, for example, livestock or poultry. One most preferred example of the vaccine according to the present invention is an infectious bronchitis virus (IBV) vaccine, which is effective against various isolated IBV strains, and which is expected to be sufficiently applicable even to cases where a mutant strain appeared. Another preferred example of the vaccine according to the present invention is a PRRSV vaccine, which was confirmed to have an effect that reduces fever, lung lesion development, and the like caused by the infection.Type: ApplicationFiled: January 24, 2019Publication date: May 13, 2021Applicants: NATIONAL FEDERATION OF AGRICULTURAL COOPERATIVE ASSOCIATIONSInventors: Tetsuya UCHIDA, Makoto NAKANISHI, Ryouichi SHIMA, Takanori NAMIMATSU, Goro SUZUKI
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Patent number: 10207310Abstract: A method for manufacturing a vehicle structure member by using a hollow extruded material that has a pair of side plates and a plurality of connecting plates connecting the side plates together and that has a quadrilateral closed section and a longitudinal shape, such that a width dimension of the vehicle structure member, which is a distance between the side plates, varies in a longitudinal direction of the vehicle structure member, the method including: an extrusion molding step of producing the hollow extruded material with the connecting plates each having a bent shape by extrusion molding; and a widening step of increasing the width dimension by increasing the distance between the side plates partially in the longitudinal direction so as to flatten the connecting plates having the bent shape.Type: GrantFiled: August 8, 2014Date of Patent: February 19, 2019Assignee: TOYODA IRON WORKS CO., LTD.Inventors: Makoto Nakanishi, Yutaka Yamada
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Publication number: 20170320455Abstract: A vehicle body front structure including: a bumper beam; side member; and crash-box including a polygonal-tubular-body, the crash-box between the bumper beam end and side member with the tubular body parallel axis to the vehicle front-rear direction, wherein the crash-box absorbs impact energy as the tubular body is collapsed under compressive load applied from the bumper beam. The polygonal-tubular-body includes outer and inner sidewalls, wherein the outer and inner sidewalls are inclined laterally outwardly in the vehicle as they approach the bumper beam, wherein the outer sidewall inclination angle with respect to the vehicle front-rear direction is greater than the inner sidewall inclination angle. The bumper beam has at the end a first portion whose front side surface is perpendicular to the vehicle front-rear direction, extending from the terminal of the beam inwardly at least to the same lateral location as the laterally outer side of the side member.Type: ApplicationFiled: November 26, 2015Publication date: November 9, 2017Applicant: TOYODA IRON WORKS CO., LTD.Inventors: Takeshi NAKAYAMA, Makoto NAKANISHI, Michio SUZUMORI, Yoshiaki HIGASHI
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Publication number: 20170262411Abstract: For each process unit, a calculator allocates, in a storing unit, a first storage area with a storage capacity corresponding to the total data volume obtained by adding the data volume of rows and columns included in the process unit to the data volume of a predetermined count of rows and columns. Using the first storage area, the calculator performs first factorization on the rows and columns of each target process unit and rows and columns transferred from process units having already undergone factorization processing. The calculator allocates, in the storing unit, a second storage area when there are, among rows and columns determined to be transferred as a result of the first factorization, those that do not fit in and are left out of the first storage area. The calculator performs second factorization on the left-out rows and columns using the second storage area.Type: ApplicationFiled: March 7, 2017Publication date: September 14, 2017Applicant: FUJITSU LIMITEDInventor: MAKOTO NAKANISHI
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Publication number: 20170106429Abstract: A method for manufacturing a vehicle structure member by using a hollow extruded material that has a pair of side plates and a plurality of connecting plates connecting the side plates together and that has a quadrilateral closed section and a longitudinal shape, such that a width dimension of the vehicle structure member, which is a distance between the side plates, varies in a longitudinal direction of the vehicle structure member, the method including: an extrusion molding step of producing the hollow extruded material with the connecting plates each having a bent shape by extrusion molding; and a widening step of increasing the width dimension by increasing the distance between the side plates partially in the longitudinal direction so as to flatten the connecting plates having the bent shape.Type: ApplicationFiled: August 8, 2014Publication date: April 20, 2017Applicant: TOYODA IRON WORKS CO., LTD.Inventors: Makoto NAKANISHI, Yutaka YAMADA
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Patent number: 9595715Abstract: This invention relates to an anode active material comprising at least one iron oxide selected from the group consisting of amorphous iron oxides, ferrihydrite, and lepidocrocite. The invention also relates to a lithium ion secondary battery anode material comprising the anode active material as a constituent component, a lithium ion secondary battery anode comprising the lithium ion secondary battery anode material, and a lithium ion secondary battery comprising the lithium ion secondary battery anode.Type: GrantFiled: December 27, 2012Date of Patent: March 14, 2017Assignee: National University Corporation Okayama UniversityInventors: Jun Takada, Hideki Hashimoto, Tatsuo Fujii, Makoto Nakanishi, Ryoji Kanno, Genki Kobayashi, Mikio Takano
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Patent number: 9566924Abstract: A vehicle shock absorbing member, which has a tubular shape having a plurality of flat plate-shaped sidewalls and having a closed section, in which, of the plurality of sidewalls, each of a pair of sidewalls located on right and left sides and separated from each other in a lateral direction of a vehicle has a groove portion formed extending in an axial direction of the tubular shape so as to be recessed inward, which is disposed between a vehicle body-side member and a bumper member in such an attitude that the axial direction corresponds to a longitudinal direction of the vehicle, and which, when subjected to a compressive load, is crushed like an a bellows in the axial direction to absorb impact energy, a pair of flat plate-shaped partition walls being formed in the tubular shape integrally with the tubular shape so as to be separated from each other in a vertical direction and so as to couple the pair of sidewalls, and the upper partition wall being tilted downward and the lower partition wall being tilteType: GrantFiled: September 12, 2013Date of Patent: February 14, 2017Assignee: Toyoda Iron Works Co., Ltd.Inventors: Makoto Nakanishi, Yutaka Yamada
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Publication number: 20170029033Abstract: A tubular reinforcement for a vehicle including a tubular portion having a sheet metal rolled to have closed edges, and an integral attachment portion formed from the same sheet metal, the attachment portion extending longitudinally from a tubular portion end and having a planar attachment base. The attachment base is raised to bring forward the contact surface, forming a peripheral wall. The tubular reinforcement is disposed in the vehicle so that an attachment base contact surface closely contacts a mounting location in the vehicle. The attachment portion lateral edges have lateral flanges on the peripheral wall opposite sides extending along with the peripheral wall toward the contact surface plane. The peripheral wall and the lateral flanges form turnback portions on both sides of the attachment base, each turnback portions defining a concavity recessed from the contact surface and having a U- or J-shaped section perpendicular to a tubular portion centerline.Type: ApplicationFiled: April 1, 2014Publication date: February 2, 2017Applicant: TOYODA IRON WORKS CO., LTD.Inventors: Kazuaki KITAGUCHI, Akira OBAYASHI, Makoto NAKANISHI, Takeshi NAKAYAMA
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Publication number: 20160203105Abstract: An information processing method including processes of; generating from a complex asymmetric sparse matrix an elimination tree of a symmetric matrix of the complex asymmetric sparse matrix; based on the generated elimination tree, extracting a row subtree of each of rows of a lower triangular matrix of the complex asymmetric sparse matrix and a row subtree of each of rows of a transposed matrix of an upper triangular matrix of the complex asymmetric sparse matrix; and determining an amount of memory area to store a result of LU factorization of the complex asymmetric sparse matrix, based on the number of row subtrees including nodes of the elimination tree, of the extracted row subtrees of the rows of the lower triangular matrix, and the number of row subtrees including nodes of the elimination tree, of the extracted row subtrees of the rows of the transposed matrix of the upper triangular matrix.Type: ApplicationFiled: December 3, 2015Publication date: July 14, 2016Inventor: Makoto NAKANISHI
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Patent number: 9266484Abstract: A crush box includes a tubular body having a polygonal section and disposed between an end portion of a bumper beam and a vehicle body in such a posture that an axial direction of the tubular body generally coincides with a longitudinal direction of a vehicle, in which the tubular body has an outer side wall and an inner side wall that is located inward of the outer side wall in a vehicle-width direction, and both the outer side wall and the inner side wall are inclined outward in the vehicle-width direction, in a direction from the vehicle body toward the bumper beam, and in which the tubular body is crushed into a bellows shape to absorb impact energy as a compressive load is applied to the tubular body from the bumper beam in the axial direction of the tubular body, wherein an angle of inclination of the outer side wall is greater than an angle of inclination of the inner side wall.Type: GrantFiled: May 21, 2014Date of Patent: February 23, 2016Assignee: Toyoda Iron Works Co., Ltd.Inventors: Makoto Nakanishi, Kazuaki Kitaguchi
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Publication number: 20160001725Abstract: A vehicle shock absorbing member, which has a tubular shape having a plurality of flat plate-shaped sidewalls and having a closed section, in which, of the plurality of sidewalls, each of a pair of sidewalls located on right and left sides and separated from each other in a lateral direction of a vehicle has a groove portion formed extending in an axial direction of the tubular shape so as to be recessed inward, which is disposed between a vehicle body-side member and a bumper member in such an attitude that the axial direction corresponds to a longitudinal direction of the vehicle, and which, when subjected to a compressive load, is crushed like an a bellows in the axial direction to absorb impact energy, a pair of flat plate-shaped partition walls being formed in the tubular shape integrally with the tubular shape so as to be separated from each other in a vertical direction and so as to couple the pair of sidewalls, and the upper partition wall being tilted downward and the lower partition wall being tilteType: ApplicationFiled: September 12, 2013Publication date: January 7, 2016Applicant: TOYODA IRON WORKS CO., LTD.Inventors: Makoto NAKANISHI, Yutaka YAMADA
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Patent number: 9184741Abstract: There is provided a semiconductor switch apparatus that can handle a wide range of input voltages. The switch apparatus includes a main switch that is provided between a first terminal and a second terminal, and a switch controller that, to turn on the main switch, supplies the same gate-source voltage to the main switch irrespective of a direction of a current flowing through the main switch. To turn on the main switch, the switch controller supplies the gate-source voltage that is determined based on at least one of a voltage of the first terminal and a voltage of the second terminal to a gate of the main switch.Type: GrantFiled: April 19, 2013Date of Patent: November 10, 2015Assignee: ADVANTEST CORPORATIONInventors: Yoshiyuki Hata, Makoto Nakanishi, Masahiko Takikawa
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Patent number: 9150094Abstract: A vehicle radiator core support, includes: a support main body including upper and lower support portions, and paired side support portions connecting right and left ends of the upper and lower support portions; and a center brace connecting intermediate parts of the upper and lower support portions. At least the lower support portion and the center brace are integrally formed. A lower-side connection portion is disposed where the lower support portion connects to the center brace, and a lower-side connection portion cross section has a U-shape opening toward a front or rear of the vehicle. A lower-side adjacent portion is disposed at a part of the lower support portion adjacent to the lower-side connection portion, such that a partition wall is between the lower-side connection and adjacent portions, and a lower-side adjacent portion cross section has a U-shape opening opposite to that of the lower-side connection portion.Type: GrantFiled: May 20, 2014Date of Patent: October 6, 2015Assignee: Toyoda Iron Works Co., Ltd.Inventor: Makoto Nakanishi
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Patent number: 9139146Abstract: A vehicular impact absorber including: a hollow tubular body having a plurality of flat plate-shaped side walls and having a polygonal section; and a vehicle body-side attachment plate that is fixed integrally with the tubular body via a bracket in a state where the vehicle body-side attachment plate is in contact with one end portion of the tubular body in an axial direction, the vehicular impact absorber being fixed at the vehicle body-side attachment plate to a vehicle body-side member, and the vehicular impact absorber absorbing impact energy as the tubular body is crushed in the axial direction when an impact load is applied to the tubular body through the other end portion of the tubular body in the axial direction, the vehicular impact absorber being configured such that the bracket has a fixed plate portion that has a prescribed length in the axial direction of the tubular body.Type: GrantFiled: September 20, 2012Date of Patent: September 22, 2015Assignee: TOYODA IRON WORKS CO., LTD.Inventor: Makoto Nakanishi
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Publication number: 20150115118Abstract: A vehicle radiator core support, includes: a support main body including upper and lower support portions, and paired side support portions connecting right and left ends of the upper and lower support portions; and a center brace connecting intermediate parts of the upper and lower support portions. At least the lower support portion and the center brace are integrally formed. A lower-side connection portion is disposed where the lower support portion connects to the center brace, and a lower-side connection portion cross section has a U-shape opening toward a front or rear of the vehicle. A lower-side adjacent portion is disposed at a part of the lower support portion adjacent to the lower-side connection portion, such that a partition wall is between the lower-side connection and adjacent portions, and a lower-side adjacent portion cross section has a U-shape opening opposite to that of the lower-side connection portion.Type: ApplicationFiled: May 20, 2014Publication date: April 30, 2015Applicant: TOYODA IRON WORKS CO., LTD.Inventor: Makoto NAKANISHI
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Publication number: 20150108775Abstract: A crush box includes a tubular body having a polygonal section and disposed between an end portion of a bumper beam and a vehicle body in such a posture that an axial direction of the tubular body generally coincides with a longitudinal direction of a vehicle, in which the tubular body has an outer side wall and an inner side wall that is located inward of the outer side wall in a vehicle-width direction, and both the outer side wall and the inner side wall are inclined outward in the vehicle-width direction, in a direction from the vehicle body toward the bumper beam, and in which the tubular body is crushed into a bellows shape to absorb impact energy as a compressive load is applied to the tubular body from the bumper beam in the axial direction of the tubular body, wherein an angle of inclination of the outer side wall is greater than an angle of inclination of the inner side wall.Type: ApplicationFiled: May 21, 2014Publication date: April 23, 2015Applicant: TOYODA IRON WORKS CO., LTD.Inventors: Makoto NAKANISHI, Kazuaki KITAGUCHI
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Publication number: 20150061307Abstract: A vehicular impact absorber including: a hollow tubular body having a plurality of flat plate-shaped side walls and having a polygonal section; and a vehicle body-side attachment plate that is fixed integrally with the tubular body via a bracket in a state where the vehicle body-side attachment plate is in contact with one end portion of the tubular body in an axial direction, the vehicular impact absorber being fixed at the vehicle body-side attachment plate to a vehicle body-side member, and the vehicular impact absorber absorbing impact energy as the tubular body is crushed in the axial direction when an impact load is applied to the tubular body through the other end portion of the tubular body in the axial direction, the vehicular impact absorber being configured such that the bracket has a fixed plate portion that has a prescribed length in the axial direction of the tubular body.Type: ApplicationFiled: September 20, 2012Publication date: March 5, 2015Applicant: TOYODA IRON WORKS CO., LTD.Inventor: Makoto Nakanishi