Abstract: It is intended to provide a salt of a compound and crystals thereof useful as a therapeutic and/or preventive agent for infectious diseases which has wide and excellent antibacterial activity and has excellent safety. [Solution] The present invention provides the hydrochloride of 7-[(1R,5S)-1-amino-5-fluoro-3-azabicyclo[3.3.0]octan-3-yl]-6-fluoro-1-[(1R,2S)-2-fluorocyclopropan-1-yl]-1,4-dihydro-8-methyl-4-oxoquinoline-3-carboxylic acid and crystals thereof, as a novel salt form of the compound and crystals thereof.

Abstract: A compound represented by the following general formula (I) or a pharmacologically acceptable salt thereof, wherein A represents a C3 to C12 cycloalkyl group which may be substituted by one to three selected from a fluoro group, a hydroxy group, a C1 to C6 alkyl group, etc; R1, R2, and R3 each independently represent a hydrogen atom, a fluoro group, or a C1 to C6 alkyl group; R4 represents a hydrogen atom or a prodrug group; and Y represents —CH2—CHR5—CH2—NHR6 (wherein R5 represents a hydrogen atom, a C1 to C6 alkyl group, or a C1 to C6 alkoxy group, and R6 represents a hydrogen atom or a prodrug group), or the like exhibits excellent TAFIa inhibitory activity and is useful as a therapeutic drug for myocardial infarction, angina pectoris, acute coronary syndrome, cerebral infarction, deep vein thrombosis, pulmonary embolism, and the like.

Abstract: Methods, apparatuses, and computer program products for memory access to a dual in-line memory module (DIMM) form factor flash memory are provided. Embodiments include receiving, by a controller from a processor through cacheable memory in the processor, a read request; transmitting, by the controller, the read request to the DIMM form factor flash memory; polling, by the controller, a read queue in the DIMM form factor flash memory until data is ready for the read request; copying from the DIMM form factor flash memory, by the controller, the data corresponding to the read request to a read queue in the controller; transmitting, by the controller on an interface between the controller and the processor, an invalidate command for the cacheable memory; and in response to receiving the invalidate command, reading by the processor the data stored in the read queue in the controller.

Abstract: Disclosed are a device, a system, and a method for setting standard work times that take real-world manufacturing capabilities into account. Provided is a standard work time calculation device (10), which analyzes fluctuations in production line assessment indices on a per time period basis, and computes standard work times for each region, as classified according to the degree of fluctuation. The standard work time calculation device (10) comprises a fluctuation coefficient computation unit (111), which computes coefficients of fluctuation for the assessment indices, a fluctuation region identification unit (112), which identifies regions of fluctuation with coefficients of fluctuation that are greater than or equal to predetermined thresholds, and a standard work time computation unit (113), which computes standard work times for regions of fluctuation.

Abstract: Provided is a material that can be easily biaxially oriented, homogeneously stretched even with a high draw ratio, and formed into a polytetrafluoroethylene porous membrane with low pressure loss. The present invention relates to a polytetrafluoroethylene mixture comprising: a modified polytetrafluoroethylene; and a fibrillable polytetrafluoroethylene homopolymer, the modified polytetrafluoroethylene having an extrusion pressure to a cylinder, at a reduction ratio of 1600, of 70 MPa or higher.

Abstract: In one embodiment, a manufacturing method for magnetic heads includes classifying magnetic heads into one of: a first tested head class, and a non-test-candidate head class, determining characteristic values of the magnetic heads classified in the first tested head class, estimating characteristic values of the magnetic heads classified in the non-test-candidate head class, wherein the estimating is based on the characteristic values of the magnetic heads classified in the first tested head class, classifying each of the magnetic heads classified in the non-test-candidate head class into one of: a second tested head class, and a non-test head class based on the estimated characteristic values, determining characteristic values of the magnetic heads classified in the second tested head class, and screening magnetic heads in the second tested head class based on the determined characteristic values of the magnetic heads classified in the second tested head class.

Abstract: An object of the present invention is to provide a novel crystal form of a compound that has an inhibitory effect on activated blood coagulation factor X and is useful as a pharmaceutical compound for prevention and/or treatment of thrombotic and/or embolic diseases. The present invention provides a novel crystal form of N1-(5-chloropyridin-2-yl)-N2-((1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-{[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino}cyclohexyl)ethanediamide p-toluenesulfonate monohydrate, and method for producing the same.

Abstract: In imaging a sample using an electron microscope, in order to reduce a time for focusing, a scanning range of a Z coordinate is reduced to complete focusing by obtaining SEM images such that: for a first predetermined number of portions, focal positions of an electron beam in obtaining each SEM image are moved in a predetermined range; then, a curved surface shape of the surface of the sample is estimated by using information relating to the focal positions of the electron beam in the first predetermined number of portions; after the images are taken, the range in which the focal positions of the electron beam are moved for scanning the electron beam on the surface of the sample is made to be narrower than the predetermined range by using the curved surface information estimated, thereby performing scanning to take the images of the sample.

Abstract: A compound represented by the following general formula (I) or a pharmacologically acceptable salt thereof, wherein A represents a C3 to C12 cycloalkyl group which may be substituted by one to three selected from a fluoro group, a hydroxy group, a C1 to C6 alkyl group, etc; R1, R2, and R3 each independently represent a hydrogen atom, a fluoro group, or a C1 to C6 alkyl group; R4 represents a hydrogen atom or a prodrug group; and Y represents —CH2—CHR5—CH2—NHR6 (wherein R5 represents a hydrogen atom, a C1 to C6 alkyl group, or a C1 to C6 alkoxy group, and R6 represents a hydrogen atom or a prodrug group), or the like exhibits excellent TAFIa inhibitory activity and is useful as a therapeutic drug for myocardial infarction, angina pectoris, acute coronary syndrome, cerebral infarction, deep vein thrombosis, pulmonary embolism, and the like.

Abstract: A load-unload ramp structure with a cantilevered fin portion to reduce drop shock in a hard-disk drive (HDD). The load-unload ramp structure includes a first load-unload ramp, a fin, and a bracket portion. The first load-unload ramp is configured to lift a first head-slider away from a magnetic-recording disk. The fin is coupled to the first load-unload ramp and is disposed below a first parking position of the first head-slider. The fin includes a fin base portion and a first cantilevered fin portion. The first cantilevered fin portion is coupled to, and extends outward from, the fin base portion. The bracket portion is integrally attached to the first load-unload ramp, and is configured to allow affixing the load-unload ramp structure in a static position in a disk-enclosure base of the HDD. A HDD including the load-unload ramp structure and a method for providing protection from drop shock are also provided.

Abstract: A load-unload ramp structure with a cantilevered fin portion to reduce drop shock in a hard-disk drive (HDD). The load-unload ramp structure includes a first load-unload ramp, a fin, and a bracket portion. The first load-unload ramp is configured to lift a first head-slider away from a magnetic-recording disk. The fin is coupled to the first load-unload ramp and is disposed below a first parking position of the first head-slider. The fin includes a fin base portion and a first cantilevered fin portion. The first cantilevered fin portion is coupled to, and extends outward from, the fin base portion. The bracket portion is integrally attached to the first load-unload ramp, and is configured to allow affixing the load-unload ramp structure in a static position in a disk-enclosure base of the HDD. A HDD including the load-unload ramp structure and a method for providing protection from drop shock are also provided.

Abstract: A computing system with physically remote shared computer memory, the computing system including: a remote memory management module, a plurality of computing devices, a plurality of remote memory modules that are external to the plurality of computing devices, and a remote memory controller, the remote memory management module configured to partition the physically remote shared computer memory amongst a plurality of computing devices; each computing device including a computer processor and a local memory controller, the local memory controller including: a processor interface, a local memory interface, and a local interconnect interface; each remote memory controller including: a remote memory interface and a remote interconnect interface, wherein the remote memory controller is operatively coupled to the data communications interconnect via the remote interconnect interface such that the remote memory controller is coupled for data communications with the local memory controller over the data communication

Abstract: A computing system with physically remote shared computer memory, the computing system including: a remote memory management module, a plurality of computing devices, a plurality of remote memory modules that are external to the plurality of computing devices, and a remote memory controller, the remote memory management module configured to partition the physically remote shared computer memory amongst a plurality of computing devices; each computing device including a computer processor and a local memory controller, the local memory controller including: a processor interface, a local memory interface, and a local interconnect interface; each remote memory controller including: a remote memory interface and a remote interconnect interface, wherein the remote memory controller is operatively coupled to the data communications interconnect via the remote interconnect interface such that the remote memory controller is coupled for data communications with the local memory controller over the data communication

Abstract: It is intended to provide a salt of a compound and crystals thereof useful as a therapeutic and/or preventive agent for infectious diseases which has wide and excellent antibacterial activity and has excellent safety. [Solution] The present invention provides the hydrochloride of 7-[(1R,5S)-1-amino-5-fluoro-3-azabicyclo[3.3.0]octan-3-yl]-6-fluoro-1-[(1R,2S)-2-fluorocyclopropan-1-yl]-1,4-dihydro-8-methyl-4-oxoquinoline-3-carboxylic acid and crystals thereof, as a novel salt form of the compound and crystals thereof.

Abstract: An object of the present invention is to provide a novel salt form of a compound that exhibits an inhibitory effect on activated blood coagulation factor X, and is useful as a preventive and/or therapeutic drug for thrombotic diseases, and crystals thereof. The present invention provides N1-(5-chloropyridin-2-yl)-N2-((1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-{[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino}cyclohexyl)ethanediamide tartrate and crystals thereof, as a novel salt form of N1-(5-chloropyridin-2-yl)-N2-((1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-{[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino}cyclohexyl)ethanediamide and crystals thereof.

Abstract: A compound represented by the following general formula (I) or a pharmacologically acceptable salt thereof, wherein A represents a C3 to C12 cycloalkyl group which may be substituted by one to three selected from a fluoro group, a hydroxy group, a C1 to C6 alkyl group, etc; R1, R2, and R3 each independently represent a hydrogen atom, a fluoro group, or a C1 to C6 alkyl group; R4 represents a hydrogen atom or a prodrug group; and Y represents —CH2—CHR5—CH2—NHR6 (wherein R5 represents a hydrogen atom, a C1 to C6 alkyl group, or a C1 to C6 alkoxy group, and R6 represents a hydrogen atom or a prodrug group), or the like exhibits excellent TAFIa inhibitory activity and is useful as a therapeutic drug for myocardial infarction, angina pectoris, acute coronary syndrome, cerebral infarction, deep vein thrombosis, pulmonary embolism, and the like.

Abstract: Methods, apparatuses, and computer program products for memory access to a dual in-line memory module (DIMM) form factor flash memory are provided. Embodiments include receiving, by a controller from a processor through cacheable memory in the processor, a read request; transmitting, by the controller, the read request to the DIMM form factor flash memory; polling, by the controller, a read queue in the DIMM form factor flash memory until data is ready for the read request; copying from the DIMM form factor flash memory, by the controller, the data corresponding to the read request to a read queue in the controller; transmitting, by the controller on an interface between the controller and the processor, an invalidate command for the cacheable memory; and in response to receiving the invalidate command, reading by the processor the data stored in the read queue in the controller.

Abstract: In order to allow to easily specify inspection recipe with which defects desired to be detected can be detected efficiently, a defect inspection apparatus performs defect inspection of a substrate in accordance with a plurality of inspection recipes and produces defect information associated with position of defect in the substrate and attribute data of the defect for each of the inspection recipes and a defect review apparatus produces review result information specifying a kind of defect selected from defects contained in the defect information. An analyzing apparatus obtains defect information and review result information and totalizes the number of defects having attribute data similar to attribute data possessed in defects corresponding to kind of defects to be analyzed for each inspection recipe.

Abstract: The transformer includes a bobbin, a plurality of terminal electrode, a primary coil, a secondary coil, and a hook part. The bobbin includes a core portion extending in an axial direction, and terminal bases fixed at both ends of the core portion in the axial direction. The plurality of terminal electrode regions is provided on the terminal bases. Each terminal electrode region is provided with a wire connection part. The primary coil comprises a plurality of primary wires. The secondary coil comprises a plurality of secondary wires. The hook part is disposed between the core portion and one of the terminal electrode regions and configured to hook at least one of the primary wires and the secondary wires.

Abstract: A computer program product and computer implemented method are provided for migrating a virtual machine between servers. The virtual machine is initially operated on a first server, wherein the first server accesses the virtual machine image over a network at a memory location within fabric attached memory. The virtual machine is migrated from the first server to a second server by flushing data to the virtual machine image from cache memory associated with the virtual machine on the first server and providing the state and memory location of the virtual machine to the second server. The virtual machine may then operate on the second server, wherein the second server accesses the virtual machine image over the network at the same memory location within the fabric attached memory without copying the virtual machine image.