Abstract: The present invention provides a specific combination of colon cancer markers based on statistical knowledge, which is capable of detecting a larger number of colon cancer patients in an earlier stage while maintaining high specificity. A multiplex colon cancer marker panel comprising a combination of five colon cancer markers of Carcinoembryonic antigen-related cell adhesion molecule 5, Carbohydrate antigen 19-9, Galectin-4, APEX nuclease and Actin-related protein 2. A method for analyzing colon cancer markers using multiplex colon cancer marker panel.

Abstract: The present invention provides a railroad vehicle which makes it possible: not only to separate a high-voltage cable involving a point of problem and sound high-voltage cables from each other without an operator climbing onto the roof of a vehicle; but also to automatically conduct the separating work without necessity for any special work. The railroad vehicle of the present invention is formed by dispersedly mounting a plurality of vehicles with main power devices that are supplied with power from a power supply line through a pantograph and constitute power supply units. The railroad vehicle includes: a plurality of vehicle units in which respective vehicles are coupled; a cable placed astride the vehicles to connect the power supply unit of each vehicle unit; and a disconnector that is installed at some midpoint in the cable and electrically separates the vehicle units from one another.

Abstract: A ?-Ga2O3-based single crystal substrate includes an average dislocation density of less than 7.31×104 cm?2. The average dislocation density may be not more than 6.14×104 cm?2. The substrate may further include a main surface including a plane orientation of (?201), (101) or (001). The substrate may be free from any twinned crystal.

Abstract: According to the present invention, a grain oriented electrical steel sheet in which iron loss has been further reduced can be obtained by carrying out decarburization annealing as continuous annealing including: (1) heating the steel sheet to a temperature in the range of 700° C. to 750° C. at heating rate of 50° C./second or higher at least in a temperature range of 500° C. to 700° C. in an atmosphere having oxidation potential P(H2O)/P(H2) equal to or lower than 0.05; (2) then cooling the steel sheet to a temperature range below 700° C. in an atmosphere having oxidation potential P(H2O)/P(H2) equal to or lower than 0.05; and (3) reheating the steel sheet to a temperature in the range of 800° C. to 900° C. and retaining the steel sheet at the temperature for soaking in an atmosphere having oxidation potential P(H2O)/P(H2) equal to or higher than 0.3.

Abstract: A liquid discharge head includes a substrate, a heat resistor layer, and a side wall member that forms a side wall of a pressure chamber. The heat resistor layer has a heat effect portion configured to foam liquid in an interior of the pressure chamber to discharge liquid from a discharge port. The heat effect portion is apart from the substrate, at least part of a surface of the heat resistor layer is covered with a covering layer in the interior of the pressure chamber, and the covering layer extends from the interior of the pressure chamber to a position coming into contact with the side wall of the side wall member.

Abstract: An annealing separator for a grain oriented electrical steel sheet does not inhibit the flowability of an atmospheric gas during the final annealing of the coil-shaped product and can prevent the occurrence of surface roughness. The annealing separator contains 0.01-0.05 mass % of Cl, 0.05-0.15 mass % of B, 0.1-2 mass % of CaO and 0.03-1.0 mass % of P2O3, and is mainly composed of magnesia having: a degree of activity of citric acid of 30-120 seconds as measured at 40% CAA; a specific surface area of 8-50 m2/g as measured by a BET method; an amount of hydration of 0.5-5.2 mass % as measured in terms of ignition loss; and a content of particles each having a particle diameter of 45 ?m or more of 0.1 mass % or less, the annealing separator further containing a water-insoluble compound having a particle diameter of 45-150 ?m inclusive in an amount of 0.05-20 mass % inclusive.

Abstract: An object of the present invention is to provide a method for inhibiting activation of signaling pathway mediated by ErbB2 in a human cell and a signaling inhibitor to be used therefor. The above-described activation of signaling pathway can be inhibited by a polypeptide comprising at least one of PTB domain or ERK2 binding domain of human FRS2?. The above-described polypeptide may be introduced directly into a cell, or nucleic acid which encodes for the above-described polypeptide may be introduced into a cell to allow expression of the polypeptide in the cell. Such polypeptide and nucleic acid can be used, for example, as a signaling inhibitor. In addition, since ErbB2 is involved in development of cancer, the above-described signaling inhibitor is also useful, for example, as an anticancer drug.

Abstract: A liquid ejection head includes a substrate which has an energy-generating element that generates energy to be utilized for ejecting a liquid, and a supply orifice for supplying the liquid to the energy-generating element; and an ejection orifice forming member that has a plurality of ejection orifices through which the liquid is ejected, and at least one beam-like projection which projects toward the substrate and extends along an array direction of the ejection orifices at a position corresponding to the supply orifice. A sectional area perpendicular to the array direction of the ejection orifices at the central part of the beam-like projection in the array direction of the ejection orifices is larger than a sectional area in the direction perpendicular to the array direction of the ejection orifices at both ends of the beam-like projection in the array direction.

Abstract: A lightweight metal spoiler is integrated with a tailgate of an automotive vehicle. The integrated tailgate spoiler is formed from the same material as the frame or rear portion of the tailgate body, preferably aluminum, in one arrangement and from different materials in another arrangement. First and second spoiler portions are joined together along overlapping, mating, abutting edges. The first and second portions of the tailgate are brazed together at an acute angle and the unitary spoiler is fused to the rear portion of the tailgate body.

Abstract: A worm biasing structure biasing a worm engaged with a worm wheel includes a radial bearing and an elastic body. The radial bearing supports the worm in a radial direction. The elastic body has elasticity and biases the radial bearing toward the worm wheel in a biasing direction. The elastic body includes a low-spring rate elastic body and a high-spring rate elastic body having a higher spring rate than that of the low-spring rate elastic body in series in the biasing direction.

Abstract: A method of making a nozzle chip includes a step of reduction-projection-exposing a photosensitive resin material to exposure light through a mask by using a reduction-projection-exposure apparatus, the mask having a light-transmitting pattern formed thereon; and a step of forming an ejection orifice pattern corresponding to the light-transmitting pattern on the photosensitive resin material by performing a developing operation. The exposure light in the step of reduction-projection-exposing is passed through a correction mechanism before the exposure light reaches the photosensitive resin material, the correction mechanism being configured to suppress an inclination of a chief ray due to off-axis telecentricity that occurs in the reduction-projection-exposure apparatus.

Abstract: A reproduction information acquiring unit acquires information identifying content streams reproduced by the information processing apparatus. A content information acquiring unit acquires, from a communicating terminal apparatus, information identifying the content streams being reproduced by the communicating terminal apparatus. A display processing unit generates a display screen to be displayed on a display, by using the information acquired respectively by the reproduction information acquiring unit and the content information acquiring unit. A screen display unit displays the display screen generated.

Abstract: A ?-Ga2O3-based single crystal substrate includes a ?-Ga2O3-based single crystal. The ?-Ga2O3-based single crystal includes a full width at half maximum of an x-ray rocking curve of less than 75 seconds.

Abstract: In a method for producing a grain-oriented electrical steel sheet by hot rolling a steel slab containing, in terms of mass %, C: 0.001˜0.20%, Si: 1.0˜5.0%, Mn: 0.03˜1.0%, one or two of S and Se: 0.005˜0.040% in total, sol. Al: 0.003˜0.050% and N: 0.0010˜0.020%, subjecting to a cold rolling to a final thickness and to a primary recrystallization annealing, applying an annealing separator composed mainly of MgO and then subjecting to final annealing, a heating rate S1 at a zone of 500˜600° C. in a heating process of the primary recrystallization annealing is not less than 100° C./s and a heating rate S2 at a zone of 600˜700° C. is a range of 30˜(0.5×S1)° C./s and an oxidation potential PH2O/PH2 of an atmosphere at a zone of 500˜700° C. is preferably not more than 0.05, whereby secondary recrystallized grains are refined over a full length of a product coil to decrease an iron loss.

Abstract: The objective of the present invention is to provide a relay apparatus capable of performing normal relay transmission for broadcast waves by preventing effects caused by wraparound in a relay apparatus. For broadcast waves received by a relay apparatus (2), the same broadcast data are placed in each of a defined segment (f0) and a first segment (f1) other than the defined segment, whereupon the relay apparatus removes broadcast data for the defined segment (f0) from the received broadcast waves, and transmits broadcast waves in which the broadcast data for the first segment (f1) have been exchanged with each of the defined segment (f0) and a second segment (f2) other than the defined segment and the first segment. As a result, the defined segment (f0) which imparts wraparound effects to the received broadcast waves is removed, and therefore, it is possible to perform normal relay transmission of the broadcast waves.

Abstract: An optical recording medium includes a recording layer including a reflective layer, two dielectric layers, and a phase-change recording layer. The phase-change recording layer-side dielectric layer of the two dielectric layers contains tantalum oxide or a composite oxide composed of silicon oxide, indium oxide, and zirconium oxide. The reflective layer-side dielectric layer of the two dielectric layers contains a composite oxide composed of silicon oxide, indium oxide, and zirconium oxide, a composite oxide composed of indium oxide and gallium oxide, or a composite oxide composed of zinc oxide and aluminum oxide.

Abstract: [Problem] To provide a light-emitting device which does not undergo the deterioration in luminous efficiency associated with the long-term use. [Solution] A light-emitting device (1) comprises a light-emitting element (10) which can emit blue light and a phosphor (2) which is composed of a single kind of single crystal and can emit yellow light upon the irradiation with the light emitted from the light-emitting element (10) which serves as excitation light. Thus, it becomes possible to prevent the deterioration in luminous efficiency associated with the deterioration in a binder or the like compared with a light-emitting device which utilizes multiple kinds of granular phosphors, because any binder for binding phosphors to each other is not required in the light-emitting device (1).

Abstract: An object of this invention is to provide a crucible for growing a sapphire single crystal, which is optimized for providing a sapphire single crystal and is reusable. A crucible for growing a sapphire single crystal of this invention includes: a base material (3) containing molybdenum as a main component and having a crucible shape; and a coating layer (5) with which only an inner periphery of the base material (3) is coated and which is formed of tungsten and inevitable impurities, in which the coating layer (5) has a surface roughness Ra of 5 ?m or more and 20 ?m or less.

Abstract: A liquid ejection head is provided with a recording element substrate having a plurality of ejection orifices for ejecting a liquid, the plurality of ejection orifices being arranged to form a row of the ejection orifices. In at least some of the plurality of the ejection orifices, each having one side and another side, the area of an inner wall of the ejection orifices is set to be larger on the other side than on the one side, the one side and the other side being defined by a plane which passes through the center of the ejection orifice, intersects with the row of the ejection orifices at right angles and extends along the direction of the depth of the ejection orifice.

Abstract: Method for manufacturing an optical lens in which coating solution curing conditions are satisfied and a coating solution is cured. The coating solution curing conditions include the angle of the axis of an optical lens substrate with respect to the horizontal direction falls within a predetermined angle range, and a second condition that the optical lens substrate rotates around the axis at a predetermined rotational speed. The predetermined angle range is between a maximum inclination angle of the axis at which the peripheral edge of a lens surface is positioned at the highest position of the lens surface, and a maximum inclination angle of the axis at which the peripheral edge of the lens surface is positioned at the lowest position of the lens surface. The predetermined rotational speed is a speed at which the coating solution applied to the lens surface is held in a coating position.