Abstract: A needle actuator assembly for a drug delivery system includes a housing, a needle having retracted and extended positions, a needle actuator body received within the housing and configured to move from a pre-use position where the needle is in the retracted position to a use position where the needle is in the extended position and to a post-use position where the needle is in the retracted position, with the needle actuator having a button contact surface, and an actuator button received by the housing.

Abstract: A drug delivery device includes a housing, a fluid reservoir received within the housing, a drive assembly configured to dispense fluid from the fluid reservoir, a needle hub actuator attached to the housing, and a needle hub at least partially received by the housing. The needle hub includes a hub body, a needle holder with a needle attached to the needle holder, and a cannula holder with a cannula attached to the cannula holder. The needle hub actuator is configured to move the needle holder and the cannula holder from a retracted position where the needle and the cannula are positioned within the hub body to an insertion position where the needle and the cannula are positioned within the hub body. The needle hub is detachable from the housing.