Patents by Inventor Malcolm Walden

Malcolm Walden has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Buprenorphine-wafer for drug substitution therapy
    Publication number: 20190216797
    Abstract: The present invention relates to oral pharmaceutical dosage forms comprising buprenorphine with the dosage form releasing buprenorphine instantly upon oral, preferably sublingual, application of the dosage form. The present invention also relates to the use of such dosage forms for treating pain in a human or animal or for drug substitution therapy in drug-dependent human subjects.
    Type: Application
    Filed: August 17, 2018
    Publication date: July 18, 2019
    Inventors: Alexander Oksche, William Heath, Timothy Holden, Derek A. Prater, Richard S. Sackler, Malcolm Walden
  • Hydromorphone and naloxone for treatment of pain and opioid bowel dysfunction syndrome
    Patent number: 10258616
    Abstract: The present invention relates to prolonged release pharmaceutical dosage forms comprising hydromorphone or a pharmaceutically acceptable salt thereof and naloxone or a pharmaceutically acceptable salt thereof for use in the treatment of pain.
    Type: Grant
    Filed: November 10, 2017
    Date of Patent: April 16, 2019
    Assignee: Euro-Celtique S.A.
    Inventors: Helen Kathleen Danagher, Hassan Mohammad, Malcolm Walden, Geoffrey Gerard Hayes, Jonathon Oliver Whitehouse, Thinnayam Naganathan Krishnamurthy, Ricardo Alberto Vargas Rincon
  • Manufacturing of active-free granules and tablets comprising the same
    Patent number: 9993433
    Abstract: The present invention relates to prolonged release pharmaceutical dosage forms, the manufacture thereof as well as their use for administration to human beings.
    Type: Grant
    Filed: May 10, 2011
    Date of Patent: June 12, 2018
    Assignee: Euro-Celtique S.A.
    Inventors: Geoffrey Gerard Hayes, Hassan Mohammad, Harjit Tamber, Malcolm Walden
  • ALCOHOL RESISTANT DOSAGE FORMS
    Publication number: 20180153812
    Abstract: Opioid controlled release formulation resistant to alcohol extraction of the opioid.
    Type: Application
    Filed: February 1, 2018
    Publication date: June 7, 2018
    Inventors: Richard O. Mannion, William H. Mckenna, Edward P. O'donnell, Helen Kathleen Danagher, Geoffrey Gerard Hayes, Hassan Mohammad, Derek Allan Prater, Harjit Tamber, Malcolm Walden, Steve Whitelock, Wolfgang Fleischer, Udo Hahn, Christof Spitzley, Christian Leuner
  • IMMEDIATE RELEASE PHARMACEUTICAL COMPOSITIONS COMPRISING OXYCODONE AND NALOXONE
    Publication number: 20180064704
    Abstract: The present invention pertains to oral immediate release pharmaceutical compositions suitable for treating patients suffering from pain comprising oxycodone and naloxone or their pharmaceutically acceptable salts.
    Type: Application
    Filed: November 7, 2017
    Publication date: March 8, 2018
    Inventors: Helen Kathleen DANAGHER, Geoffrey Gerard HAYES, Gerhard Josef HEUN, Hassan MOHAMMAD, Malcolm WALDEN, Jonathon Oliver WHITEHOUSE
  • HYDROMORPHONE AND NALOXONE FOR TREATMENT OF PAIN AND OPIOID BOWEL DYSFUNCTION SYNDROME
    Publication number: 20180064705
    Abstract: The present invention relates to prolonged release pharmaceutical dosage forms comprising hydromorphone or a pharmaceutically acceptable salt thereof and naloxone or a pharmaceutically acceptable salt thereof for use in the treatment of pain.
    Type: Application
    Filed: November 10, 2017
    Publication date: March 8, 2018
    Inventors: Helen Kathleen DANAGHER, Hassan MOHAMMAD, Malcolm WALDEN, Geoffrey Gerard HAYES, Jonathon Oliver WHITEHOUSE, Thinnayam Naganathan KRISHNAMURTHY, Ricardo Alberto VARGAS RINCON
  • Combination of active loaded granules with additional actives
    Patent number: 9901540
    Abstract: The present invention relates to prolonged release pharmaceutical dosage forms, the manufacture thereof as well as their use for administration to human being.
    Type: Grant
    Filed: May 10, 2011
    Date of Patent: February 27, 2018
    Assignee: Euro-Celtique S.A.
    Inventors: Hassan Mohammad, Malcolm Walden, Geoffrey Gerard Hayes, Harjit Tamber
  • BUPRENORPHINE WAFER FOR DRUG SUBSTITUTION THERAPY
    Publication number: 20180008595
    Abstract: The present invention relates to oral pharmaceutical dosage forms comprising buprenorphine with the dosage form releasing buprenorphine instantly upon oral, preferably sublingual, application of the dosage form. The present invention also relates to the use of such dosage forms for treating pain in a human or animal or for drug substitution therapy in drug-dependent human subjects.
    Type: Application
    Filed: September 19, 2017
    Publication date: January 11, 2018
    Inventors: Alexander OKSCHE, William HEATH, Timothy HOLDEN, Derek A. PRATER, Richard S. SACKLER, Malcolm WALDEN
  • Buprenorphine-wafer for drug substitution therapy
    Patent number: 9861628
    Abstract: The present invention relates to oral pharmaceutical dosage forms comprising buprenorphine with the dosage form releasing buprenorphine instantly upon oral, preferably sublingual, application of the dosage form. The present invention also relates to the use of such dosage forms for treating pain in a human or animal or for drug substitution therapy in drug-dependent human subjects.
    Type: Grant
    Filed: April 22, 2016
    Date of Patent: January 9, 2018
    Assignee: RHODES PHARMACEUTICALS L.P.
    Inventors: Alexander Oksche, William Heath, Timothy Holden, Derek A. Prater, Richard S. Sackler, Malcolm Walden
  • Immediate release pharmaceutical compositions comprising oxycodone and naloxone
    Patent number: 9820983
    Abstract: The present invention pertains to oral immediate release pharmaceutical compositions suitable for treating patients suffering from pain comprising oxycodone and naloxone or their pharmaceutically acceptable salts.
    Type: Grant
    Filed: January 21, 2016
    Date of Patent: November 21, 2017
    Assignee: Purdue Pharma L.P.
    Inventors: Helen Kathleen Danagher, Geoffrey Gerard Hayes, Gerhard Josef Heun, Hassan Mohammad, Malcolm Walden, Jonathon Oliver Whitehouse
  • Hydromorphone and naloxone for treatment of pain and opioid bowel dysfunction syndrome
    Patent number: 9814710
    Abstract: The present invention relates to prolonged release pharmaceutical dosage forms comprising hydromorphone or a pharmaceutically acceptable salt thereof and naloxone or a pharmaceutically acceptable salt thereof for use in the treatment of pain.
    Type: Grant
    Filed: November 13, 2014
    Date of Patent: November 14, 2017
    Assignee: Euro-Celtique S.A.
    Inventors: Helen Kathleen Danagher, Hassan Mohammad, Malcolm Walden, Geoffrey Gerard Hayes, Jonathon Oliver Whitehouse, Thinnayam Naganathan Krishnamurthy, Ricardo Alberto Vargas Rincon
  • Opioid composition for treating skin lesions
    Patent number: 9782359
    Abstract: The present invention relates to a composition, comprising (i) a matrix made of polymeric nanofibers, and (ii) an opioid agonist within the matrix.
    Type: Grant
    Filed: May 5, 2009
    Date of Patent: October 10, 2017
    Assignee: EURO-CELTIQUE S.A.
    Inventors: Alexander Oksche, Kevin J. Smith, Derek Prater, Malcolm Walden, Will Heath, Bernard Kennedy, Vanessa Addison
  • Buprenorphine-wafer for drug substitution therapy
    Patent number: 9763931
    Abstract: The present invention relates to oral pharmaceutical dosage forms comprising buprenorphine with the dosage form releasing buprenorphine instantly upon oral, preferably sublingual, application of the dosage form. The present invention also relates to the use of such dosage forms for treating pain in a human or animal or for drug substitution therapy in drug-dependent human subjects.
    Type: Grant
    Filed: April 22, 2016
    Date of Patent: September 19, 2017
    Assignee: PURDUE PHARMA L.P.
    Inventors: Alexander Oksche, William Heath, Timothy Holden, Derek A. Prater, Richard S. Sackler, Malcolm Walden
  • Pharmaceutical compositions comprising hydromorphone and naloxone
    Patent number: 9700508
    Abstract: The present invention relates to prolonged release pharmaceutical dosage forms, the manufacture thereof as well as their use for administration to human beings.
    Type: Grant
    Filed: May 10, 2011
    Date of Patent: July 11, 2017
    Assignee: Euro-Celtique S.A.
    Inventors: Helen Kathleen Danagher, Hassan Mohammad, Malcolm Walden, Geoffrey Gerard Hayes, Jonathon Oliver Whitehouse, Thinnayam Naganathan Krishnamurthy, Ricardo Alberto Vargas Rincon
  • Buprenorphine-Wafer for Drug Substitution Therapy
    Publication number: 20170157062
    Abstract: The present invention relates to oral pharmaceutical dosage forms comprising buprenorphine with the dosage form releasing buprenorphine instantly upon oral, preferably sublingual, application of the dosage form. The present invention also relates to the use of such dosage forms for treating pain in a human or animal or for drug substitution therapy in drug-dependent human subjects.
    Type: Application
    Filed: February 24, 2017
    Publication date: June 8, 2017
    Inventors: Alexander OKSCHE, William HEATH, Timothy HOLDEN, Derek A. PRATER, Richard S. SACKLER, Malcolm WALDEN
  • Extrusion
    Patent number: 9603802
    Abstract: The invention relates to a process for preparing a controlled release pharmaceutical extrudate using a melt extruder, wherein the melt extruder comprises a die-head supporting a die-plate in which orifices are located, and a cutter adjacent to the die-head, and wherein the cutter cuts the extruded mix as it emerges under pressure and still molten or softened from the orifices of the die-plate.
    Type: Grant
    Filed: September 30, 2008
    Date of Patent: March 28, 2017
    Assignee: Euro-Celtique S.A.
    Inventors: Geoffrey Gerard Hayes, Vincenzo Martinelli, Hassan Mohammad, Derek Allan Prater, Harjit Tamber, Malcolm Walden, Steve Whitelock
  • ALCOHOL RESISTANT DOSAGE FORMS
    Publication number: 20170079923
    Abstract: Opioid controlled release formulation resistant to alcohol extraction of the opioid.
    Type: Application
    Filed: December 1, 2016
    Publication date: March 23, 2017
    Inventors: Richard O. MANNION, William H. MCKENNA, Edward P. O'DONNELL, Helen Kathleen DANAGHER, Geoffrey Gerard HAYES, Hassan MOHAMMAD, Derek Allan PRATER, Harjit TAMBER, Malcolm WALDEN, Steve WHITELOCK, Wolfgang FLEISCHER, Udo HAHN, Christof SPITZLEY, Christian LEUNER
  • HYDROMORPHONE AND NALOXONE FOR TREATMENT OF PAIN AND OPIOID BOWEL DYSFUNCTION SYNDROME
    Publication number: 20160296516
    Abstract: The present invention relates to prolonged release pharmaceutical dosage forms comprising hydromorphone or a pharmaceutically acceptable salt thereof and naloxone or a pharmaceutically acceptable salt thereof for use in the treatment of pain.
    Type: Application
    Filed: November 13, 2014
    Publication date: October 13, 2016
    Inventors: Helen Kathleen DANAGHER, Hassan MOHAMMAD, Malcolm WALDEN, Geoffrey Gerard HAYES, Jonathon Oliver WHITEHOUSE, Thinnayam Naganathan KRISHNAMURTHY, Ricardo Alberto VARGAS RINCON
  • BUPRENORPHINE WAFER FOR DRUG SUBSTITUTION THERAPY
    Publication number: 20160235739
    Abstract: The present invention relates to oral pharmaceutical dosage forms comprising buprenorphine with the dosage form releasing buprenorphine instantly upon oral, preferably sublingual, application of the dosage form. The present invention also relates to the use of such dosage forms for treating pain in a human or animal or for drug substitution therapy in drug-dependent human subjects.
    Type: Application
    Filed: April 22, 2016
    Publication date: August 18, 2016
    Inventors: Alexander OKSCHE, William HEATH, Timothy HOLDEN, Derek A. PRATER, Richard S. SACKLER, Malcolm WALDEN
  • Buprenorphine-wafer for drug substitution therapy
    Publication number: 20160235738
    Abstract: The present invention relates to oral pharmaceutical dosage forms comprising buprenorphine with the dosage form releasing buprenorphine instantly upon oral, preferably sublingual, application of the dosage form. The present invention also relates to the use of such dosage forms for treating pain in a human or animal or for drug substitution therapy in drug-dependent human subjects.
    Type: Application
    Filed: April 22, 2016
    Publication date: August 18, 2016
    Inventors: Alexander OKSCHE, William HEATH, Timothy HOLDEN, Derek A. PRATER, Richard S. SACKLER, Malcolm WALDEN