Patents by Inventor Mallikarjun Sundaram

Mallikarjun Sundaram has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANALYSIS OF SULFATED POLYSACCHARIDES
    Publication number: 20130065852
    Abstract: The invention relates to methods and products associated with analyzing and monitoring heterogeneous populations of sulfated polysaccharides. In particular therapeutic heparin products including low molecular weight heparin products and methods of analyzing and monitoring these products are described.
    Type: Application
    Filed: September 4, 2012
    Publication date: March 14, 2013
    Inventors: Ganesh Venkataraman, Zachary Shriver, Mallikarjun Sundaram, Yi-wei Qi, Ram Sasisekharan
  • METHODS AND PRODUCTS RELATED TO LOW MOLECULAR WEIGHT HEPARIN
    Publication number: 20130017565
    Abstract: The invention relates to methods and products for characterizing and using polysaccharides. Low molecular weight heparin products and methods of use are described. Methods for characterizing purity and activity of polysaccharide preparations including glycosaminoglycans such as heparin are also described.
    Type: Application
    Filed: May 7, 2012
    Publication date: January 17, 2013
    Applicant: Massachusetts Institute of Technology
    Inventors: Ram Sasisekharan, Ganesh Venkataraman, Zachary Shriver, Dongfang Liu, Mallikarjun Sundaram, Yiwei Qi
  • Methods for analyzing or processing a heparin sample
    Patent number: 8173384
    Abstract: The invention relates to methods and products for analyzing or processing a heparin sample. In one embodiment, the methods comprise contacting the sample with heparinase I, heparinase II and heparinase III, determining the amount of a signature component in the sample using a separation method, and making a determination about the sample based upon a comparison of the amount of the signature component in the sample to a reference database for a heparin.
    Type: Grant
    Filed: July 27, 2009
    Date of Patent: May 8, 2012
    Assignee: Massachusetts Institute of Technology
    Inventors: Ram Sasisekharan, Ganesh Venkataraman, Zachary Shriver, Dongfang Liu, Mallikarjun Sundaram, Yiwei Qi
  • Analysis of sulfated polysaccharides
    Patent number: 7947507
    Abstract: The invention relates to methods and products associated with analyzing and monitoring heterogeneous populations of sulfated polysaccharides. In particular therapeutic heparin products including low molecular weight heparin products and methods of analyzing and monitoring these products are described.
    Type: Grant
    Filed: September 3, 2008
    Date of Patent: May 24, 2011
    Assignee: Momenta Pharmaceuticals, Inc.
    Inventors: Ganesh Venkataraman, Zachary Shriver, Mallikarjun Sundaram, Yi Wei Qi, Ram Sasisekharan
  • POLYSACCHARIDE COMPOSITIONS AND METHODS OF USE FOR THE TREATMENT AND PREVENTION OF DISORDERS ASSOCIATED WITH PROGENITOR CELL MOBILIZATION
    Publication number: 20100324276
    Abstract: Polysaccharide preparations lacking substantial anticoagulant activity are provided herein. Methods of making and using such preparations are provided.
    Type: Application
    Filed: April 16, 2010
    Publication date: December 23, 2010
    Applicant: MOMENTA PHARMACEUTICALS, INC.
    Inventors: Mallikarjun SUNDARAM, Takashi Kei KISHIMOTO, Sucharita ROY
  • POLYSACCHARIDE COMPOSITIONS AND METHODS OF USE FOR THE TREATMENT AND PREVENTION OF DISORDERS ASSOCIATED WITH PROGENITOR CELL MOBILIZATION
    Publication number: 20100316640
    Abstract: Polysaccharide preparations lacking substantial anticoagulant activity are provided herein. Methods of making and using such preparations are provided.
    Type: Application
    Filed: June 15, 2010
    Publication date: December 16, 2010
    Applicant: Momenta Pharmaceuticals, Inc.
    Inventors: Mallikarjun SUNDARAM, Takashi Kei KISHIMOTO, Sucharita ROY
  • LOW MOLECULAR WEIGHT HEPARIN COMPOSITION AND USES THEREOF
    Publication number: 20100305022
    Abstract: Preparations of low molecular weight heparins (LMWHs) having improved properties, e.g., properties that provide a clinical advantage, are provided herein. Methods of making and using such preparations as well as methods of analyzing starting materials, processing, intermediates and final products in the production of such LMWH preparations are provided.
    Type: Application
    Filed: May 26, 2010
    Publication date: December 2, 2010
    Inventors: Zachary Shriver, Mallikarjun Sundaram, Ganesh Venkataraman, Pat Oliver-Shaffer, Yiming Yao, Zainab Sirajbhai Mamuwala, Ian David Fier, Yiwei Qi, Ishan Capila, Nur Sibel Gunay, Daniela Beccati, Cuihua Liu, Corinne Bauer, Ying Li
  • NON-ANTICOAGULANT POLYSACCHARIDE COMPOSITIONS
    Publication number: 20100298260
    Abstract: Preparations of polysaccharides lacking substantial anticoagulant activity are provided herein. Methods of making and using such preparations are provided.
    Type: Application
    Filed: November 3, 2008
    Publication date: November 25, 2010
    Applicant: MOMENTA PHARMACEUTICALS, INC.
    Inventors: Mallikarjun Sundaram, Takashi Kei Kishimoto, Sucharita Roy
  • Methods and products related to pulmonary delivery of polysaccharides
    Patent number: 7709461
    Abstract: The invention relates to methods for delivering polysaccharides by a pulmonary route to achieve local and systemic therapeutic effects. The polysaccharides may be formulated or unformulated and in some instances have an extremely fast absorption rate.
    Type: Grant
    Filed: October 18, 2001
    Date of Patent: May 4, 2010
    Assignee: Massachusetts Institute of Technology
    Inventors: Dongfang Liu, Yiwei Qi, Ganesh Venkataraman, Mallikarjun Sundaram, Ram Sasisekharan
  • Methods and producing low molecular weight heparin
    Patent number: 7687479
    Abstract: The invention relates, in part, to methods and products related to producing low molecular weight heparin.
    Type: Grant
    Filed: September 8, 2006
    Date of Patent: March 30, 2010
    Assignee: Massachusetts Institute of Technology
    Inventors: Ram Sasisekharan, Ganesh Venkataraman, Zachary Shriver, Dongfang Liu, Mallikarjun Sundaram, Yiwei Qi
  • METHODS AND PRODUCTS RELATED TO LOW MOLECULAR WEIGHT HEPARIN
    Publication number: 20100062468
    Abstract: The invention relates to methods and products for characterizing and using polysaccharides. Low molecular weight heparin products and methods of use are described. Methods for characterizing purity and activity of polysaccharide preparations including glycosaminoglycans such as heparin are also described.
    Type: Application
    Filed: July 27, 2009
    Publication date: March 11, 2010
    Applicant: Massachusetts Institute of Technology
    Inventors: Ram Sasisekharan, Ganesh Venkataraman, Zachary Shriver, Dongfang Liu, Mallikarjun Sundaram, Yiwei Qi
  • Methods for evaluating the quality of a heparin sample
    Patent number: 7585642
    Abstract: The invention relates to methods and products for characterizing and using polysaccharides. Low molecular weight heparin products and methods of use are described. Methods for characterizing purity and activity of polysaccharide preparations including glycosaminoglycans such as heparin are also described.
    Type: Grant
    Filed: November 30, 2006
    Date of Patent: September 8, 2009
    Assignee: Massachusetts Institute of Technology
    Inventors: Ram Sasisekharan, Ganesh Venkataraman, Zachary Shriver, Dongfang Liu, Mallikarjun Sundaram, Yiwei Qi
  • Methods and products related to evaluating the quality of a polysaccharide
    Patent number: 7399604
    Abstract: The invention relates to methods and products for characterizing and using polysaccharides. Low molecular weight heparin products and methods of use are described. Methods for characterizing purity and activity of polysaccharide preparations including glycosaminoglycans such as heparin are also described.
    Type: Grant
    Filed: July 15, 2005
    Date of Patent: July 15, 2008
    Assignee: Massachusetts Institute of Technology
    Inventors: Ram Sasisekharan, Ganesh Venkataraman, Zachary Shriver, Dongfang Liu, Mallikarjun Sundaram, Yiwei Qi
  • Low molecular weight heparin composition and uses thereof
    Publication number: 20070287683
    Abstract: Preparations of low molecular weight heparins (LMWHs) having improved properties, e.g., properties that provide a clinical advantage, are provided herein. Methods of making and using such preparations as well as methods of analyzing starting materials, processing, intermediates and final products in the production of such LMWH preparations are provided.
    Type: Application
    Filed: May 24, 2007
    Publication date: December 13, 2007
    Inventors: Zachary Shriver, Mallikarjun Sundaram, Ganesh Venkataraman, Pat Oliver-Shaffer, Yiming Yao, Zainab Mamuwala, Ian Fier, Yiwei Qi, Ishan Capila, Nur Gunay, Daniela Beccati, Cuihua Liu, Corinne Bauer, Ying Li
  • Methods and products related to evaluating the quality of a polysaccharide
    Publication number: 20070161073
    Abstract: The invention relates to methods and products for characterizing and using polysaccharides. Low molecular weight heparin products and methods of use are described. Methods for characterizing purity and activity of polysaccharide preparations including glycosaminoglycans such as heparin are also described.
    Type: Application
    Filed: November 30, 2006
    Publication date: July 12, 2007
    Applicant: Massachusetts Institute of Technology
    Inventors: Ram Sasisekharan, Ganesh Venkataraman, Zachary Shriver, Dongfang Liu, Mallikarjun Sundaram, Yiwei Qi
  • Methods and products related to producing low molecular weight heparin
    Publication number: 20070065921
    Abstract: The invention relates to methods and products for characterizing and using polysaccharides. Low molecular weight heparin products and methods of use are described. Methods for characterizing purity and activity of polysaccharide preparations including glycosaminoglycans such as heparin are also described.
    Type: Application
    Filed: September 8, 2006
    Publication date: March 22, 2007
    Applicant: Massachusetts Institute Of Technology
    Inventors: Ram Sasisekharan, Ganesh Venkataraman, Zachary Shriver, Dongfang Liu, Mallikarjun Sundaram, Yiwei Qi
  • Methods and products related to the analysis of polysaccarides
    Patent number: 7083937
    Abstract: The invention relates to methods and products for characterizing and using polysaccharides. Low molecular weight heparin products and methods of use are described. Methods for characterizing purity and activity of polysaccharide preparations including glycosaminoglycans such as heparin are also described.
    Type: Grant
    Filed: September 12, 2001
    Date of Patent: August 1, 2006
    Assignee: Massachusetts Institute of Technology
    Inventors: Ram Sasisekharan, Ganesh Venkataraman, Zachary Shriver, Dongfang Liu, Mallikarjun Sundaram, Yiwei Qi
  • Methods and products related to evaluating the quality of a polysaccharide
    Publication number: 20060024664
    Abstract: The invention relates to methods and products for characterizing and using polysaccharides. Low molecular weight heparin products and methods of use are described. Methods for characterizing purity and activity of polysaccharide preparations including glycosaminoglycans such as heparin are also described.
    Type: Application
    Filed: July 15, 2005
    Publication date: February 2, 2006
    Applicant: Massachusetts Institute of Technology
    Inventors: Ram Sasisekharan, Ganesh Venkataraman, Zachary Shriver, Dongfang Liu, Mallikarjun Sundaram, Yiwei Qi
  • Glycan markers for diagnosing and monitoring disease
    Publication number: 20040147033
    Abstract: The present invention provides ultra-sensitive methods for detecting changes in glycosylation that are correlated with pre-cancerous or early cancerous states. Because the chance of complete recovery is increased with earlier detection of cancer, the present invention provides therapeutically useful methods of early detection, diagnosis, staging and prognostication.
    Type: Application
    Filed: December 19, 2003
    Publication date: July 29, 2004
    Inventors: Zachary Shriver, Ganesh Venkataraman, Ram Sasisekharan, Mallikarjun Sundaram
  • Methods and products for mucosal delivery
    Publication number: 20040087543
    Abstract: The invention features methods and products associated with non-invasive delivery of polysaccharide preparations.
    Type: Application
    Filed: April 25, 2003
    Publication date: May 6, 2004
    Inventors: Zachary Shriver, Ganesh Venkataraman, Mallikarjun Sundaram, Ram Sasisekharan, Thomas Richardson, Yiwei Qi