Patents by Inventor Manal Ahmed Gasmelseed Awad

Manal Ahmed Gasmelseed Awad has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11925666
    Abstract: Bee venom nanoparticles and methods of synthesizing bee venom nanoparticles are provided. The bee venom nanoparticles may be synthesized by drying bee venom, suspending the dried bee venom in a solvent to form a first bee venom solution, spraying the first bee venom solution into boiling water under ultrasonic conditions to form a bee venom solution including the bee venom nanoparticles, stirring the bee venom solution including the bee venom nanoparticles, and freeze-drying the bee venom solution. The resulting nanoparticles may be used in pharmaceutical compositions, and may be useful for their antimicrobial activities.
    Type: Grant
    Filed: March 23, 2021
    Date of Patent: March 12, 2024
    Assignee: KING SAUD UNIVERSITY
    Inventors: Reem Atta Alajmi, Nadin Mohamed Moubayed, Manal Ahmed Gasmelseed Awad, Hany Mohamed Yehia, Manal Fawzy Elkhadragy, Ibrahim Abdullah Barakat, Faten Nasser Alsaqabi, Amany Zein Elabedein Mahmoud Elshahidy
  • Patent number: 11718537
    Abstract: A method of synthesizing copper oxide nanoparticles includes preparing a liquid extract of Rumex vesicarius, dissolving copper salt in the liquid extract to provide a solution with copper nanoparticles, adding a base to the solution with copper nanoparticles to form a precipitate including copper oxide nanoparticles. Copper oxide nanoparticles prepared according to the method are effective photocatalysts for degrading organic dyes and antibacterial agents and exhibit anticancer activities.
    Type: Grant
    Filed: March 23, 2021
    Date of Patent: August 8, 2023
    Assignee: KING SAUD UNIVERSITY
    Inventors: Ali Aldalbahi, Raneem Aldawish, Manal Ahmed Gasmelseed Awad, Noura Saleem Aldosari, Reem Hamad Alshathri, Leen Abdullah Aldwihi, Raghad Alammari, Khloud Ibrahim Bin Shoqiran
  • Patent number: 11694853
    Abstract: The flexible dye-sensitized solar panel with an organic chromophore is formed from an organic chromophore dye in a polymer matrix. The organic chromophore dye is extracted from chard (B. vulgaris subsp. cicla). The polymer matrix may be formed from either poly(vinyl alcohol) or polystyrene. The flexible dye-sensitized solar panel with an organic chromophore is made by preparing a solution of the selected polymer in the dye extracted from the B. vulgaris subsp. cicla. The solution is coated on a glass plate and dried to form a thin film. The thin flexible film is removed from the plate, forming the flexible dye-sensitized solar panel with an organic chromophore.
    Type: Grant
    Filed: December 9, 2020
    Date of Patent: July 4, 2023
    Assignee: KING SAUD UNIVERSITY
    Inventors: Manal Ahmed Gasmelseed Awad, Awatif Ahmed Hendi, Khalid Mustafa Osman Ortashi
  • Patent number: 11643334
    Abstract: The copper oxide nanoparticles synthesized using Rhatany root extract involves preparing the Rhatany root extract by adding powdered Rhatany roots to boiling water, allowing the mixture to soak overnight, and removing any solid residue by filtering to obtain the aqueous extract. The copper oxide nanoparticles are prepared by mixing equal volumes of the aqueous Rhatany root extract and 0.1 M aqueous copper sulfate, heating the mixture at 80° C. for 40 minutes, and adding 1 M sodium hydroxide dropwise to the mixture to precipitate CuO. The precipitate is removed by centrifuge, washed with ethanol, dried, and calcined at 400° C. for 4 hours to obtain the copper oxide nanoparticles. The resulting nanoparticles proved effective in degrading wastewater dyes, showed anticancer activity against human cervical cancer by cell viability assay, and showed antibacterial activity against various strains of bacteria by agar diffusion.
    Type: Grant
    Filed: April 12, 2021
    Date of Patent: May 9, 2023
    Assignee: KING SAUD UNIVERSITY
    Inventors: Ali Aldalbahi, Bushra Ibarahim Alabdullah, Manal Ahmed Gasmelseed Awad, Shaykha Mohammed Alzahly, Zainah Ali Alqahtani, Shorouq Mohsen Alsaggaf, Hessa Abdullah Aljasser, Hind Ali Abdullah Alshehri
  • Patent number: 11617719
    Abstract: The Moringa oleifera nanoparticles may be synthesized by harvesting Moringa leaves, drying the Moringa leaves, powdering the dried Moringa leaves, suspending the powdered Moringa leaves in a solution, and spraying the solution into boiling water under ultrasonic conditions to obtain Moringa nanoparticles. The Moringa nanoparticles may be encapsulated by dissolving the Moringa nanoparticles and gum olibanum in ethanol to produce a mixture, injecting the inert organic phase of the mixture into an aqueous solution containing PVA, and homogenizing the aqueous solution. The Moringa nanoparticles may be useful in preventing the growth of cancer cells and in treating diabetes by inhibiting ?-glucosidase and/or ?-amylase activity.
    Type: Grant
    Filed: August 7, 2020
    Date of Patent: April 4, 2023
    Assignee: KING SAUD UNIVERSITY
    Inventors: Manal Ahmed Gasmelseed Awad, Promy Virk, Mai Abdelrahman Elobeid Wagealla, Sarah Saleh Abdulla Alsaif, Awatif Ahmed Hendi, Khalid Mustafa Osman Ortashi, Rabia Qindeel
  • Publication number: 20210403643
    Abstract: A method of synthesizing copper oxide nanoparticles includes preparing a liquid extract of Rumex vesicarius, dissolving copper salt in the liquid extract to provide a solution with copper nanoparticles, adding a base to the solution with copper nanoparticles to form a precipitate including copper oxide nanoparticles. Copper oxide nanoparticles prepared according to the method are effective photocatalysts for degrading organic dyes and antibacterial agents and exhibit anticancer activities.
    Type: Application
    Filed: March 23, 2021
    Publication date: December 30, 2021
    Inventors: ALI ALDALBAHI, RANEEM ALDAWISH, MANAL AHMED GASMELSEED AWAD, NOURA SALEEM ALDOSARI, REEM HAMAD ALSHATHRI, LEEN ABDULLAH ALDWIHI, RAGHAD ALAMMARI, KHLOUD IBRAHIM BIN SHOQIRAN
  • Publication number: 20210387862
    Abstract: The copper oxide nanoparticles synthesized using Rhatany root extract involves preparing the Rhatany root extract by adding powdered Rhatany roots to boiling water, allowing the mixture to soak overnight, and removing any solid residue by filtering to obtain the aqueous extract. The copper oxide nanoparticles are prepared by mixing equal volumes of the aqueous Rhatany root extract and 0.1 M aqueous copper sulfate, heating the mixture at 80° C. for 40 minutes, and adding 1 M sodium hydroxide dropwise to the mixture to precipitate CuO. The precipitate is removed by centrifuge, washed with ethanol, dried, and calcined at 400° C. for 4 hours to obtain the copper oxide nanoparticles. The resulting nanoparticles proved effective in degrading wastewater dyes, showed anticancer activity against human cervical cancer by cell viability assay, and showed antibacterial activity against various strains of bacteria by agar diffusion.
    Type: Application
    Filed: April 12, 2021
    Publication date: December 16, 2021
    Inventors: Ali Aldalbahi, Bushra Ibarahim Alabdullah, Manal Ahmed Gasmelseed Awad, Shaykha Mohammed Alzahly, Zainah Ali Alqahtani, Shorouq Mohsen Alsaggaf, Hessa Abdullah Aljasser, Hind Ali Abdullah Alshehri
  • Publication number: 20210260138
    Abstract: Bee venom nanoparticles and methods of synthesizing bee venom nanoparticles are provided. The bee venom nanoparticles may be synthesized by drying bee venom, suspending the dried bee venom in a solvent to form a first bee venom solution, spraying the first bee venom solution into boiling water under ultrasonic conditions to form a bee venom solution including the bee venom nanoparticles, stirring the bee venom solution including the bee venom nanoparticles, and freeze-drying the bee venom solution. The resulting nanoparticles may be used in pharmaceutical compositions, and may be useful for their antimicrobial activities.
    Type: Application
    Filed: March 23, 2021
    Publication date: August 26, 2021
    Inventors: Reem Atta Alajmi, Nadin Hohamed Moubayed, Manal Ahmed Gasmelseed Awad, Hany Mohamed Yehia, Manal Fawzy Elkhadragy, Ibrahim Abdullah Barakat, Faten Nasser Alsaqabi, Amany Zein Elabedein Mahmoud Elshahidy
  • Patent number: 11001505
    Abstract: The copper oxide nanoparticles synthesized using Rhatany root extract involves preparing the Rhatany root extract by adding powdered Rhatany roots to boiling water, allowing the mixture to soak overnight, and removing any solid residue by filtering to obtain the aqueous extract. The copper oxide nanoparticles are prepared by mixing equal volumes of the aqueous Rhatany root extract and 0.1 M aqueous copper sulfate, heating the mixture at 80° C. for 40 minutes, and adding 1 M sodium hydroxide dropwise to the mixture to precipitate CuO. The precipitate is removed by centrifuge, washed with ethanol, dried, and calcined at 400° C. for 4 hours to obtain the copper oxide nanoparticles. The resulting nanoparticles proved effective in degrading wastewater dyes, showed anticancer activity against human cervical cancer by cell viability assay, and showed antibacterial activity against various strains of bacteria by agar diffusion.
    Type: Grant
    Filed: June 16, 2020
    Date of Patent: May 11, 2021
    Assignee: KING SAUD UNIVERSITY
    Inventors: Ali Aldalbahi, Bushra Ibarahim Alabdullah, Manal Ahmed Gasmelseed Awad, Shaykha Mohammed Alzahly, Zainah Ali Alqahtani, Shorouq Mohsen Alsaggaf, Hessa Abdullah Aljasser, Hind Ali Abdullah Alshehri
  • Patent number: 10995010
    Abstract: A method of synthesizing copper oxide nanoparticles includes preparing a liquid extract of Rumex vesicarius, dissolving copper salt in the liquid extract to provide a solution with copper nanoparticles, adding a base to the solution with copper nanoparticles to form a precipitate including copper oxide nanoparticles. Copper oxide nanoparticles prepared according to the method are effective photocatalysts for degrading organic dyes and antibacterial agents and exhibit anticancer activities.
    Type: Grant
    Filed: June 26, 2020
    Date of Patent: May 4, 2021
    Assignee: KING SAUD UNIVERSITY
    Inventors: Ali Aldalbahi, Raneem Aldawish, Manal Ahmed Gasmelseed Awad, Noura Saleem Aldosari, Reem Hamad Alshathri, Leen Abdullah Aldwihi, Raghad Alammari, Khloud Ibrahim Bin Shoqiran
  • Patent number: 10980843
    Abstract: Bee venom nanoparticles and methods of synthesizing bee venom nanoparticles are provided. The bee venom nanoparticles may be synthesized by drying bee venom, suspending the dried bee venom in a solvent to form a first bee venom solution, spraying the first bee venom solution into boiling water under ultrasonic conditions to form a bee venom solution including the bee venom nanoparticles, stirring the bee venom solution including the bee venom nanoparticles, and freeze-drying the bee venom solution. The resulting nanoparticles may be used in pharmaceutical compositions, and may be useful for their antimicrobial activities.
    Type: Grant
    Filed: February 25, 2020
    Date of Patent: April 20, 2021
    Assignee: KING SAUD UNIVERSITY
    Inventors: Reem Atta Alajmi, Nadin Mohamed Moubayed, Manal Ahmed Gasmelseed Awad, Hany Mohamed Yehia, Manal Fawzy Elkhadragy, Ibrahim Abdullah Barakat, Faten Nasser Alsaqabi, Amany Zein Elabedein Mahmoud Elshahidy
  • Publication number: 20210104368
    Abstract: The flexible dye-sensitized solar panel with an organic chromophore is formed from an organic chromophore dye in a polymer matrix. The organic chromophore dye is extracted from chard (B. vulgaris subsp. cicla). The polymer matrix may be formed from either poly(vinyl alcohol) or polystyrene. The flexible dye-sensitized solar panel with an organic chromophore is made by preparing a solution of the selected polymer in the dye extracted from the B. vulgaris subsp. cicla. The solution is coated on a glass plate and dried to form a thin film. The thin flexible film is removed from the plate, forming the flexible dye-sensitized solar panel with an organic chromophore.
    Type: Application
    Filed: December 9, 2020
    Publication date: April 8, 2021
    Inventors: Manal Ahmed Gasmelseed Awad, Awatif Ahmed Hendi, Khalid Mustafa Osman Ortashi
  • Patent number: 10954264
    Abstract: The synthesis of ursolic acid nanoparticles includes dissolving ursolic acid powder in methanol, boiling water for five minutes, and adding the methanol solution to the boiled water dropwise at a flow rate of 0.1-0.3 ml/min under ultrasonic conditions. After sonication for 20 minutes, the contents are stirred for about 15 minutes, and then dried. Particle size distribution studies and TEM micrographs confirm the resulting product comprises nanoparticles. In vitro testing confirms the ursolic acid nanoparticles exhibit greater anticancer activity than conventional-size particles, and that the nanoparticles exhibit antimicrobial effect against gram positive and gram negative bacteria, as well as fungi.
    Type: Grant
    Filed: August 27, 2019
    Date of Patent: March 23, 2021
    Assignee: KING SAUD UNIVERSITY
    Inventors: Rabab Abd El Moneim Khalil El Dib, Shaza Mohamed Adel Al-Massarani, Manal Ahmed Gasmelseed Awad, Ali Ali Hasan Elgamal
  • Patent number: 10947265
    Abstract: The synthesis of ursolic acid nanoparticles includes dissolving ursolic acid powder in methanol, boiling water for five minutes, and adding the methanol solution to the boiled water dropwise at a flow rate of 0.1-0.3 ml/min under ultrasonic conditions. After sonication for 20 minutes, the contents are stirred for about 15 minutes, and then dried. Particle size distribution studies and TEM micrographs confirm the resulting product comprises nanoparticles. In vitro testing confirms the ursolic acid nanoparticles exhibit greater anticancer activity than conventional-size particles, and that the nanoparticles exhibit antimicrobial effect against gram positive and gram negative bacteria, as well as fungi.
    Type: Grant
    Filed: August 27, 2019
    Date of Patent: March 16, 2021
    Assignee: KING SAUD UNIVERSITY
    Inventors: Rabab Abd El Moneim Khalil El Dib, Shaza Mohamed Adel Al-Massarani, Manal Ahmed Gasmelseed Awad, Ali Ali Hasan Elgamal
  • Patent number: 10947266
    Abstract: The synthesis of ursolic acid nanoparticles includes dissolving ursolic acid powder in methanol, boiling water for five minutes, and adding the methanol solution to the boiled water dropwise at a flow rate of 0.1-0.3 ml/min under ultrasonic conditions. After sonication for 20 minutes, the contents are stirred for about 15 minutes, and then dried. Particle size distribution studies and TEM micrographs confirm the resulting product comprises nanoparticles. In vitro testing confirms the ursolic acid nanoparticles exhibit greater anticancer activity than conventional-size particles, and that the nanoparticles exhibit antimicrobial effect against gram positive and gram negative bacteria, as well as fungi.
    Type: Grant
    Filed: August 27, 2019
    Date of Patent: March 16, 2021
    Assignee: KING SAUD UNIVERSITY
    Inventors: Rabab Abd El Moneim Khalil El Dib, Shaza Mohamed Adel Al-Massarani, Manal Ahmed Gasmelseed Awad, Ali Ali Hasan Elgamal
  • Patent number: 10934175
    Abstract: The method of producing zinc oxide nanoparticles (ZnO NPs) using red sand includes mixing red sand with water to form an aqueous suspension of red sand, removing the supernatant from the suspension, centrifuging the supernatant and retaining a second supernatant from the centrifuged suspension, dissolving a solution of zinc nitrate in the second supernatant to form a precursor solution, and adding 1M NaOH dropwise to the precursor solution to precipitate the zinc oxide nanoparticles. The precipitate may be washed, dried and calcined to provide the red sand synthesized ZnO NPs. The red sand synthesized ZnO NPs have photocatalytic activity and can be used, for example, to degrade organic dyes in aqueous environments.
    Type: Grant
    Filed: December 2, 2019
    Date of Patent: March 2, 2021
    Assignee: King Saud University
    Inventors: Manal Ahmed Gasmelseed Awad, Ali Kanakhir Aldalbahi, Khalid Mustafa Osman Ortashi, Taghrid Saad Omar Alomar, Najla Saad Almasoud
  • Patent number: 10898533
    Abstract: Mangosteen nanoparticles and methods of synthesizing Mangosteen nanoparticles are provided. The Mangosteen nanoparticles may be synthesized by drying Mangosteen, Garcinia mangostana fruit, grinding the dried Mangosteen to form powdered Mangosteen, suspending the powdered Mangosteen in a solvent to form a first Mangosteen solution, spraying the Mangosteen solution into boiling water under ultrasonic conditions to form a second Mangosteen solution, resting the second Mangosteen solution at room temperature (about 20° C.), and freeze-drying the second Mangosteen solution to obtain Mangosteen nanoparticles. The drying step may include either air-drying or freeze-drying the Mangosteen. The Mangosteen fruit peel may be used in the drying step instead of the inner Mangosteen fruit. The resulting nanoparticles may be used in pharmaceutical compositions, and may be useful for their antioxidant and antibacterial activities.
    Type: Grant
    Filed: January 26, 2020
    Date of Patent: January 26, 2021
    Assignee: KING SAUD UNIVERSITY
    Inventors: Hany Mohamed Yehia, Manal Ahmed Gasmelseed Awad, Mohamed Fekry Serag El-Din, Hatem Salama Mohamed Ali, Reem Atta Alajmi, Dina Mahmoud Metwally Hasanin, Wafa Abdullah Al-Megrin, Manal Fawzy Elkhadragy
  • Patent number: 10886073
    Abstract: The flexible solar panel includes a polymer matrix and a plant extract incorporated in the polymer matrix. The plant extract can be an extract of chard (B. vulgaris subsp. cicla) including an organic dye. The plant extract can include chloroplasts. The polymer matrix may be formed from either poly(vinyl alcohol) or polystyrene. The flexible solar panel can be green.
    Type: Grant
    Filed: April 13, 2016
    Date of Patent: January 5, 2021
    Assignee: KING SAUD UNIVERSITY
    Inventors: Manal Ahmed Gasmelseed Awad, Awatif Ahmed Hendi, Khalid Mustafa Osman Ortashi
  • Patent number: 10856559
    Abstract: The method of producing eggshell-derived nanoparticles may include steps of adding eggshell powder to methanol to form a solution; adding the solution dropwise to boiling water under ultrasonic conditions; incubating the resulting solution under continuous stirring at 200-800 rpm; and drying the resulting solution to obtain the eggshell-derived nanoparticles. The method produces nanoparticles of between 5 and 100 nm. Cytotoxicity testing shows that the nanoparticles exhibit anticancer activity against human breast cancer and lung cancer cell lines.
    Type: Grant
    Filed: September 9, 2019
    Date of Patent: December 8, 2020
    Assignee: KING SAUD UNIVERSITY
    Inventors: Khalid Mustafa Osman Ortashi, Manal Ahmed Gasmelseed Awad, Awatif Ahmed Hendi
  • Publication number: 20200376059
    Abstract: The watermelon seed nanoparticles may be synthesized by dissolving powdered watermelon seeds in a solvent to produce a first mixture, adding the first mixture dropwise to boiling water under ultrasonic conditions to produce a second mixture, sonicating the second mixture and drying the second mixture to produce watermelon seed nanoparticles. In an embodiment, the watermelon seeds may be Citrullus lanatus seeds. In an embodiment, the watermelon seed nanoparticles may be included in a pharmaceutical composition, such as an antimicrobial or anti-cancer composition.
    Type: Application
    Filed: December 23, 2019
    Publication date: December 3, 2020
    Inventors: KHALID MUSTAFA OSMAN ORTASHI, MANAL AHMED GASMELSEED AWAD