Abstract: The present disclosure relates to methods for performing minimally invasive anatomical space access, e.g., minimally invasive subretinal access (MISA), in connection with the delivery of therapeutic modalities to an anatomical space of interest, e.g., the subretinal space, and system components adapted to facilitate such delivery.

Abstract: Provided herein are compounds of Formulae (I), (II), (III), and (III-d). Also provided herein are methods of preparation of Formulae (I), (II), and (III-d). Further provided herein are methods of functionalizing or sequencing a peptide by reaction of compounds of Formula (III-d) with peptidases.

Abstract: In some embodiments, a disclosed method includes: storing, in a database, historical data associated with existing electric vehicle charging stations, identifying a first set of locations for potential electric vehicle charging stations, determining demand forecast associated with the set of locations based on the historical data, generating a score value for each location of the first set of locations, the score value being based on the demand forecast, calculating a loss value for a first location of the first set of locations based on one or more of a second location of the first set of locations and a plurality of locations of the existing electric vehicle charging stations, and generating a second set of locations for potential electric vehicle charging stations based on the demand forecast, the score value, and the loss value, the second set being a subset of the first set.

Abstract: A cooking device comprises a power supply, a cooking pot, and a hot plate connected to the power supply and on which the cooking pot sits. The hot plate applies heat to the cooking pot. A plurality of food ingredient dispenser compartments is positioned upright in adjacent locations, aligned in a row at a front of the cooking device. A robotic arm consisting of five articulating joints provide a robotic arm with five corresponding degrees of motion.

Abstract: The present disclosure relates to systems and methods for a system lab and SOP framework to support testing based on customer environments. Longevity testing must be run on every build with different test cases; thus, the system lab framework allows this testing to be performed on multiple machines in a single run, also allowing test results to be stored. The system lab framework is adapted to recreate customer issues, allowing different environments typically not accessible to be replicated and tested. The system lab framework includes central code to trigger cases on different machines. A central data collection system is able to collect all of the results from the cases and store the respective data. This system lab framework is adapted to support multiple Operating Systems (OS) including Windows, Mac, Linux, and the like.

Abstract: A heat pump system is provided. The system includes a closed loop for refrigerant flow, including an evaporator, an expansion valve, a compressor, a heat pump heater that comprises a first condenser, and a second condenser wherein refrigerant flows continuous through loop and through the components continuously, and a flow of forced air across the heat pump heart and the evaporator. The expansion valve is remotely controllable in order to adjust a refrigerant pressure drop that occurs as refrigerant passes through the first expansion valve. During operation refrigerant may cause moisture to freeze upon the outer heat transfer surface. Periodically the first expansion valve is adjusted to decrease a pressure drop of refrigerant that flows through the first expansion valve thereby transferring heat through the evaporator and to the outer heat transfer surface to cause the frozen layer upon the outer surface of the evaporator to melt.

Abstract: Methods and systems are provided for on-device journey execution. In embodiments described herein, a selection to publish a journey on a device is received. A representation of the journey is communicated from a server to the device over a network to store the journey locally on the device. At least a portion of the journey is executed on the device using the journey stored locally on the device.

Abstract: An exit device assembly for coupling to a door having a first side and second side. A first exit device may be coupled to the first side of the door. The first exit device may include a main tube extending from a first end to a second end and a first adjustment tube coupled to the first end of the main tube. The first adjustment tube may be axially adjustable relative to the main tube along a first adjustment axis. An actuator assembly may be supported within an interior of the main tube of the first exit device and may be moveable between a first position and a second position. A latchbolt may be coupled to the actuator assembly and may be moveable between a retracted position and an extended position in which the latchbolt engages a latch.

Abstract: This document describes surgical instrument tables. For example, this document describes ergonomic surgical intervention tables that are user-friendly and easy-to-deploy. In some embodiments, the surgical intervention table is designed as an attachment for an existing catheterization or operating table. The mounting of the table is flexible as the surgical intervention table can be mounted either at the foot side or lateral side of the table, away from the operator, and can be folded back underneath it with push of a button.

Abstract: The present disclosure provides methods for sorting retinal cells for use in cellular component transfer therapy, sorted populations of retinal cells generated by such methods, and compositions comprising such sorted populations of retinal cells. The present disclosure also provides uses of sorted populations of retinal s and compositions comprising thereof for preventing and/or treating inherited retinal degenerative diseases.

Abstract: A mirror replacement system includes a camera having a frontal lens on an outer surface of the camera. The frontal lens includes an inner surface and an outer surface. A nano-etched coating is deposited on at least one of the inner and outer surfaces of the lens.

Abstract: A method for adaptively providing processed data to elements of a distributed network, includes a processor partitioning data from a plurality of data sources, including big data from a plurality of big data sources based on defined needs of the elements; the processor storing the partitioned data in a central data source and a subset of the partitioned data in one or more cache memories in proximity to the elements; receiving a data request from a network element; determining a time-sensitivity of data responsive to the data request; supplying a response to the data request for non-time-sensitive data; and supplying the response to the data request for time-sensitive data.

Abstract: A system for electrically connecting first and second load wires and first and second source wires. The system includes a lock body defining a receptacle inside the lock body. The system also includes first and second contact elements for electrically connecting the load wires and the source wires. The load wires are connectable to the first and second contact elements at first and second load ends thereof. The system includes one or more slider bodies slidably received in the receptacle, and the contact elements are partially mounted in the slider bodies. The system includes one or more pinch levers mounted to the lock body and movable from an inactive position to a locked position. When the pinch lever is moved to its locked position, the slider body is moved in the receptacle relative to the lock body, and the contact elements engage the source wires for electrical connection therewith.

Abstract: The strike assembly can have a strike with a strike face, a socket in the strike face for receiving a male locking member retractably mounted to a door, the socket having a shim-receiving wall integral to and normal to the strike face, the shim-receiving wall having a receiving aperture, an insert being securely engageable into the receiving aperture along an insert engagement path, and a shim plate held firmly in the socket, against the shim-receiving wall, by the insert, when the insert is engaged into the receiving aperture.

Abstract: The present disclosure relates to systems, methods, and non-transitory computer readable media that utilize a consolidated graphical user interface for visually presenting the state of a user profile with respect to a workflow journey. For instance, in one or more embodiments, the disclosed systems provide, for display within a graphical user interface of a client device, a visual representation of a workflow journey comprising a plurality of nodes and one or more edges connecting the plurality of nodes. Additionally, the disclosed systems receive, via the graphical user interface of the client device, an identifier associated with a user profile. The disclosed systems further modify, within the graphical user interface of the client device, the visual representation of the workflow journey to reflect a state of the user profile with respect to the workflow journey.

Abstract: A method including determining, via a machine learning model, a predicted energy load profile for a facility based at least in part on weather forecast data and sensor data for the facility. The sensor data can be received from one or more energy monitoring sensors for one or more devices in the facility. The method further can include determining one or more demand shedding time slots based at least in part on peak periods and the predicted energy load profile. Moreover, the method can include determining one or more demand shedding events for the one or more devices to be scheduled during the one or more demand shedding time slots. The method additionally can include causing a respective performance of each of the one or more demand shedding events by the one or more devices during the one or more demand shedding time slots. Other embodiments are disclosed.

Abstract: The present disclosure relates to cell-based therapeutics for retinal and macular repair comprising defined retinal cell subtypes, including short (s)-, medium (m)- and long (l) wavelength sensitive cone photoreceptors, methods for the manufacture of such cell-based therapeutics, and methods of using such therapeutics.

Abstract: The present disclosure relates to systems, methods, and non-transitory computer readable media that utilize a consolidated graphical user interface for visually presenting the state of a user profile with respect to a workflow journey. For instance, in one or more embodiments, the disclosed systems provide, for display within a graphical user interface of a client device, a visual representation of a workflow journey comprising a plurality of nodes and one or more edges connecting the plurality of nodes. Additionally, the disclosed systems receive, via the graphical user interface of the client device, an identifier associated with a user profile. The disclosed systems further modify, within the graphical user interface of the client device, the visual representation of the workflow journey to reflect a state of the user profile with respect to the workflow journey.

Abstract: The electric strike can have a housing having an internal face receivable against a receiving face of a door frame, an external strike face, a socket recessed into the strike face along a socket axis normal to the receiving face of the door frame, for receiving a male locking member retractably mounted to a door, the male locking member also being moveable transversally to the socket axis, along a horizontal escape path, by opening the door, the electric strike further having a keeper pivotally mounted around a pivot axis between a closed configuration and an open configuration, the pivot axis parallel to the socket axis and offset from the escape path on a first side of the socket, inside the housing, the keeper having a gate member forming a restraining wall of the socket blocking the escape path when in the closed configuration, and a distal end.

Abstract: Systems and methods for customer journey orchestration are described. One or more aspects of the systems and methods include identifying, by a customer journey orchestration application, a customer journey having a previously unidentified fault; initiating, by a mode selection component, a debug mode of the customer journey orchestration application for the customer journey; receiving, by a graphical user interface of the customer journey orchestration application, a user input corresponding to an event of a plurality of events of the customer journey; simulating, by an event simulation component, the event based on the user input and the debug mode; determining, by a status component, a status of the event based on the simulation; and identifying, by a fault identification component, the previously unidentified fault based on the status of the event.