Abstract: According to one embodiment, a system includes a medical device configured to provide a function to a user, communicate via a wireless communication channel with one or more other devices, and send a signal to shift a medical device application from a locked state to an unlocked state. The system also includes a computing device having wireless communication channels and a processor and logic integrated with and/or executable by the processor. The logic is configured to cause the computing device to communicate with the medical device, execute the medical device application, and shift from the locked state to the unlocked state in response to receiving the signal from the medical device. Core functionality of the medical device application is disabled when the medical device application is in the locked state, and some functionality applicable to the medical device is enabled when the medical device application is in the unlocked state.

Abstract: A system for detection of optically anisotropic tissue is provided. The system comprises an optical source, an optical detector, a processing unit and a probe. The probe has a shaft with a longitudinal axis and a front end, and a plurality of optical fibers; wherein an end of each of the optical fibers is arranged at the front end of the shaft, and at least one of the optical fibers is a source optical fiber adapted to transmit optical radiation emitted from the optical source to a tissue adjacent to the front end of the shaft. Another one of the optical fibers is a detector optical fiber adapted to transmit optical radiation reflected from the tissue to the optical detector, so that an optical path through the tissue is defined, wherein the optical paths differ from each other with respect to their spatial orientation, and wherein the optical paths cross each other.

Abstract: The present invention relates to determining a treatment response index. In order to improve and facilitate hypertension treatment procedures, a device (10) for determining a treatment response index is provided that comprises a data input (12), a data processor (14) and a data output (16). The data input is configured to receive a value (18) of at least one first measurement of a physiological parameter of a subjects vasculature under a first condition; and to provide a value (20) of at least one second measurement of the physiological parameter of the vasculature under a second condition. In the second condition, a pre-determined stimulation is provided, and the first condition is non-stimulated or at least differently stimulated. The data processor is configured to generate a treatment response index. In an example, the data output is configured to provide a classification of the subject into one of at least two groups of subjects, based on the treatment response index.

Abstract: A system and method is disclosed for measurement of pulse wave velocity of a vessel. An intravascular device comprises a first and a second marker provided at different locations along the length of the intravascular device of which positions are localizable by a tracking apparatus. The intravascular device provides plurality of measurements along the length of the vessel, while the intravascular device is moved from a first position to a second position, corresponding to a first and a second time. At the second time the position of the first marker in the vessel corresponds to the position of the second marker at the first time. The pulse wave velocity value of the vessel is ascertained based on measurements associated for the first time and the second time from the plurality of measurements and based on the distance between the locations of the two markers along the length of the intravascular device.

Abstract: The present invention relates to the supply of a sensor of an interventional device. In order to provide an interventional device with improved handling, an interventional device is provided, the device comprising a longitudinal elongated main body with a distal portion and a proximal portion; and a sensor provided on the distal portion. The elongated main body comprises a hollow shaft. The proximal portion of the main body comprises an optical energy generation section, in which the hollow shaft is at least partially provided as a transparent hypotube, and in which a doped material is provided inside the hollow shaft. Further, the doped material is configured to generate light as stimulated emission with a predetermined wavelength upon the doped material being radiated with a pumping wavelength. Still further, the transparent hypotube is configured to receive light from an external light source as a substantially transversal light input providing the pumping wavelength to the doped material.

Abstract: A seat and cooling system for the seat include a porous seat surface, an air spacer disposed on a side of the seat surface that defines an air channel, a substantially air impermeable barrier having an opening therein in communication with the air channel and a blower configured to draw air through the seat surface and from the air channel.

Abstract: A medical imaging system for identifying a target structure (TS), e.g. a tumor, in a biological tissue. A hyperspectral camera system is used for imaging a surface area (A1) of the tissue (BT), e.g. with a limited spectral resolution, but enough to allow identification of suspicious areas where the target structure (TS) may be, e.g. such areas can be visually indicated on a display to the operator. A probe (PR), e.g. an optical surface probe, is used to provide probe measurement of a smaller surface area (A2) of the tissue, but with more information indicative of the target structure. The probe is selected to provide a higher specificity with respect to identification of the target structure than the hyperspectral camera (HSC). The hyperspectral processing algorithm (PP) is then calibrated based on probe measurement data performed within the suspicious areas, thus providing a calibrated hyperspectral processing algorithm resulting in images with an enhanced sensitivity to identify the target structure.

Abstract: A System for image processing (IPS), in particular for lung imaging The system (IPS) comprises an interface (IN) for receiving at least a part of a 3D image volume (VL) acquired by an imaging apparatus (IA1) of a lung (LG) of a subject (PAT) by exposing the subject (PAT) to a first interrogating signal. A layer definer (LD) of the system (IPS) is configured to define, in the 3D image volume, a layer object (LO) that includes a representation of a surface (S) of the lung (LG). A renderer (REN) of the system (IPS) is configured to render at least a part of the layer object (LO) in 3D at a rendering view (Vp) for visualization on a display device (DD).

Abstract: A vehicle seat includes a support structure, a seat surface (14) and a molded polymeric frame (18). The frame has an edge region and the seat surface (14) is mounted to the frame (18) and the frame is mounted to the support structure. At least a portion of the edge region is flexible.

Abstract: The invention is directed to systems and methods for determining a fundamental pulse wave velocity value for a vessel with minimized effect of reflections originating from the vessel network connected distal to the respective vessel.

Abstract: According to one embodiment, a system includes a medical device configured to provide a function to a user, communicate via a wireless communication channel with one or more other devices, and send a signal to shift a medical device application from a locked state to an unlocked state. The system also includes a computing device having wireless communication channels and a processor and logic integrated with and/or executable by the processor. The logic is configured to cause the computing device to communicate with the medical device, execute the medical device application, and shift from the locked state to the unlocked state in response to receiving the signal from the medical device. Core functionality of the medical device application is disabled when the medical device application is in the locked state, and some functionality applicable to the medical device is enabled when the medical device application is in the unlocked state.

Abstract: The present invention relates to the context of renal denervation. In order to provide further improvement in relation to the outcome of renal denervation, an apparatus (10) for renal denervation preparation is provided that comprises an input unit (12), ha processing unit (14) and an output unit (16). The input unit is configured to receive first artery parameter data and second artery Ge parameter data. The first artery parameter data relates to artery stiffness of a renal artery part of a subject, and the second artery parameter In data relates to artery stiffness of a non-renal artery part of the subject.

Abstract: A load bearing surface includes a woven fabric surface and a carrier (18) overmolded onto the fabric surface. Portions of the woven fabric are bonded to the carriers(18) o as to remain fixed relative to the carrier during normal loading conditions and during abnormally high loading conditions. Other portions (14) of the woven fabric are bonded to the carrier so as to remain fixed relative to the carrier during normal loading conditions and to move or slip within the carrier, or to rupture, during abnormally high loading conditions.

Abstract: A catheter (12) has an image sensing system (S1-S5) for imaging the interior wall of a passageway in which the catheter is to be located. The catheter has a radial imaging system comprising a light source arrangement for generating a light output radially around the catheter and an image sensor for receiving the generally radial light after the light has been scattered back by the interior wall. The catheter is positioned within the passageway with a known position and orientation, for example a known angle with respect to the anterior-posterior plane along the length of the catheter, so that it is known where along the catheter length, and at which angular position around the catheter, it is close to the passageway wall. The light output has a different intensity at different radial directions and/or the catheter comprises a light transmission arrangement which gives rise to different transmission of the light output at different radial directions.

Abstract: A heater for vehicular sensors is configured to pass sensing energy and thereby permit placement of the heater directly over the sensing area in the path of the sensed energy. In this way, direct heating of the sensing area is provided minimizing the energy necessary to prevent icing and improving deicing speed.

Abstract: The present invention discloses an endovascular device arrangement (1) comprising a vascular access port (10); an endovascular device (20) for inserting into a patient's blood vessel through said vascular access port; and a near-field communication module (15) including an antenna (17), wherein at least the antenna of the near-field communication module is located within the vascular access port; and the endovascular device comprises an electronic device (25) and an antenna arrangement (21) communicatively coupled to said electronic device for maintaining a near-field communication link between the electronic device and the near-field communication module whilst the endovascular device passes through the vascular access port, said antenna arrangement comprising an array of antenna elements (21) located along a shaft of the endovascular device (20), each of said antenna elements being communicatively coupled to said electronic device (25).

Abstract: The present invention relates to a pressure sensing device (10) comprising an optical fiber (12), the optical fiber (12) comprises a central axis (L) and at least one optical fiber core (14), the at least one optical fiber core (14) having one or more reflective FBG structures, and a coating (16) surrounding the optical fiber (12), the coating (16) having mechanical properties which are radially asymmetric along the central axis (L).

Abstract: A monitoring system comprises an intra-vascular support device and a sensor mounted to the support device and projecting into the vessel. The sensor generates a signal which is dependent on the level of deformation of a free end. The sensor signal is interpreted to enable detection of changes in the length of a deformable part of the sensor thereby to determine a level of bio-layer formation and also determine a level of flow. The sensor remains able to detect flow even when a bio-layer is formed and it can also detect the presence (and thickness) of the bio-layer, because part of the sensor becomes rigid when constrained by the bio-layer.

Abstract: A monitoring system includes an implantable intra-vascular support device for positioning against a vessel wall and an implantable sensor-actuator mounted to the support device. The sensor-actuator is drivable between a non-deployed position in which it is against the support device and a deployed position in which it is displaced away from the support device. Sensor signals are generated when in the deployed position. This system is able to monitor flow away from the edge of a vessel by deploying the sensor-actuator towards the center of the vessel. When flow monitoring does not need to take place, it can be non-deployed so that it does not present an occlusion to the flow.

Abstract: The invention relates to a photonic probe apparatus and a method for probing tissue to detect and mark biological tissue with cancerous or precancerous states. The apparatus involves a probe for illuminating tissue and collecting light from an illuminated tissue region through the probe, a unit for analyzing collected light to determine whether a threshold measure of probability of a cancerous or precancerous lesion in the probed tissue region in contact with the probe is exceeded, and an integrated tissue marking facility which can be activated to mark the probed tissue region through the probe when the threshold measure is exceeded. The photonic probe apparatus and the method are especially suitable for probing regions in squamous and columnar epithelia to detect and mark regions with cervical cancer or cervical intraepithelial neoplasia (CIN).