Patents by Inventor Manfred Raschack

Manfred Raschack has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6440975
    Abstract: The invention relates to amino acid derivatives of the formula I where the radicals have the meanings stated in the description, and to the use thereof as drugs.
    Type: Grant
    Filed: March 31, 1998
    Date of Patent: August 27, 2002
    Assignee: Abbott Laboratories
    Inventors: Dagmar Klinge, Wilhelm Amberg, Andreas Kling, Hartmut Riechers, Liliane Unger, Manfred Raschack
  • Publication number: 20020098186
    Abstract: The use of endothelin inhibitors for the preparation of drugs for treatment or prevention of fibrotic disorders.
    Type: Application
    Filed: January 14, 2002
    Publication date: July 25, 2002
    Inventors: Detlef Schuppan, Manfred Raschack
  • Publication number: 20020052495
    Abstract: Carboxylic acid derivatives 1
    Type: Application
    Filed: December 27, 2000
    Publication date: May 2, 2002
    Inventors: Hartmut Riechers, Dagmar Klinge, Wilhelm Amberg, Andreas Kling, Stefan Muller, Ernst Baumann, Joachim Rheinheimer, Uwe Josef Vogelbacher, Wolfgang Wernet, Liliane Unger, Manfred Raschack
  • Patent number: 6358983
    Abstract: The present invention relates to carboxylic acid derivatives of the formula I the substituents having the meanings explained in the description, preparation and use as endothelin receptor antagonists.
    Type: Grant
    Filed: April 27, 2000
    Date of Patent: March 19, 2002
    Assignee: Abbott Laboratories
    Inventors: Wilhelm Amberg, Rolf Jansen, Heinz Hillen, Stefan Hergenröder, Manfred Raschack, Liliane Unger
  • Patent number: 6197958
    Abstract: Carboxylic acid derivatives where R—R6, X, Y and Z have the meanings stated in the description, and the preparation thereof, are described. The novel compounds are suitable for controlling diseases.
    Type: Grant
    Filed: May 11, 1999
    Date of Patent: March 6, 2001
    Assignee: BASF Aktiengesellschaft
    Inventors: Hartmut Riechers, Dagmar Klinge, Wilhelm Amberg, Andreas Kling, Stefan Müller, Ernst Baumann, Joachim Rheinheimer, Uwe Josef Vogelbacher, Wolfgang Wernet, Liliane Unger, Manfred Raschack
  • Patent number: 6103732
    Abstract: Carboxylic acid derivatives of the formula I ##STR1## where the radicals have the meanings stated in the description, and the preparation of these agreements [sic] and their use as drugs are described.
    Type: Grant
    Filed: October 8, 1998
    Date of Patent: August 15, 2000
    Assignee: BASF Aktiengesellschaft
    Inventors: Wilhelm Amberg, Andreas Kling, Dagmar Klinge, Hartmut Riechers, Ernst Baumann, Liliane Unger, Manfred Raschack, Stefan Hergenroder, Sabine Schult
  • Patent number: 6004988
    Abstract: Carboxylic acid derivatives of the formula I ##STR1## here R.sup.1 is a tetrazole [sic], nitrile [sic], a group COOH or a radical which can be hydrolyzed to COOH, and the other substituents have the meaning explained in the description.
    Type: Grant
    Filed: February 24, 1998
    Date of Patent: December 21, 1999
    Assignee: BASF Aktiengesellschaft
    Inventors: Wilhelm Amberg, Andreas Kling, Dagmar Klinge, Hartmut Riechers, Liliane Unger, Manfred Raschack, Stefan Hergenroder, Bernd Elger, Sabine Schult
  • Patent number: 5969134
    Abstract: Carboxylic acid derivatives ##STR1## where R-R.sup.6, X, Y and Z have the meanings stated in the description, and the preparation thereof, are described. The novel compounds are suitable for controlling diseases.
    Type: Grant
    Filed: November 2, 1998
    Date of Patent: October 19, 1999
    Assignee: BASF Aktiengesellschaft
    Inventors: Hartmut Riechers, Dagmar Klinge, Wilhelm Amberg, Andreas Kling, Stefan Muller, Ernst Baumann, Joachim Rheinheimer, Uwe Josef Vogelbacher, Wolfgang Wernet, Liliane Unger, Manfred Raschack
  • Patent number: 5932730
    Abstract: Carboxylic acid derivatives ##STR1## where R-R.sup.6, X, Y and Z have the meanings stated in the description, and the preparation thereof, are described. The novel compounds are suitable for controlling diseases.
    Type: Grant
    Filed: March 27, 1997
    Date of Patent: August 3, 1999
    Assignee: BASF Aktiengesellschaft
    Inventors: Hartmut Riechers, Dagmar Klinge, Wilhelm Amberg, Andreas Kling, Stefan Muller, Ernst Baumann, Joachim Rheinheimer, Uwe Josef Vogelbacher, Wolfgang Wernet, Liliane Unger, Manfred Raschack
  • Patent number: 5840722
    Abstract: A method of inhibiting endothelin receptors by administering to a patient a compound of the formula I ##STR1##
    Type: Grant
    Filed: September 30, 1996
    Date of Patent: November 24, 1998
    Assignee: BASF Aktiengesellschaft
    Inventors: Ernst Baumann, Uwe Josef Vogelbacher, Joachim Rheinheimer, Dagmar Klinge, Hartmut Riechers, Burkhard Kroger, Siegfried Bialojan, Claus Bollschweiler, Wolfgang Wernet, Liliane Unger, Manfred Raschack
  • Patent number: 5693637
    Abstract: The description relates to bicyclene derivatives of formula (I) in which A, B, D, E, G, K, L, R.sup.1, R.sup.2, Z.sup.1 and Z.sup.2 have the meanings given in the description, and their production. These compounds are suitable for treating diseases.
    Type: Grant
    Filed: June 6, 1996
    Date of Patent: December 2, 1997
    Assignee: BASF Aktiengesellschaft
    Inventors: Dagmar Klinge, Liliane Unger, Manfred Raschack, Wolfgang Wernet
  • Patent number: 5342839
    Abstract: 2-Hydroxy-3-phenoxy-propyl-substituted piperazines of the formula I ##STR1## in which R.sup.1 -R.sup.5, Y, m and n have the meaning indicated in the description, and the preparation thereof are described. The novel compounds are suitable for the therapy of oxygen deficiency diseases of the brain.
    Type: Grant
    Filed: March 18, 1991
    Date of Patent: August 30, 1994
    Assignee: BASF Aktiengesellschaft
    Inventors: Hans-Joerg Treiber, Hans P. Hofmann, Laszlo Szabo, Liliane Unger, Manfred Raschack
  • Patent number: 5260318
    Abstract: Phenylpiperidylamines of the formula I ##STR1## R.sup.1 is H, NO.sub.2, R.sup.4 SO.sub.2 NH, ##STR2## N.dbd.C, CF.sub.3, CF.sub.3 O, F, Cl, Br, C.sub.1 -C.sub.4 -alkyl, R.sup.3 O, CO.sub.2 R.sup.3, CHO, CH.dbd.NOR.sup.3, CH.sub.3 OR.sup.3 andR.sup.2 is H, F, Cl, Br, C.sub.1 -C.sub.4 -alkyl or R.sup.4 O, where R.sup.1 and R.sup.2 are not both H,R.sup.3 is H or R.sup.4,R.sup.4 is C.sub.1 -C.sub.4 -alkyl or phenyl,n is 1, 2, 3 or 4 andAr is ##STR3## and the physiologically tolerated salts thereof, are used as active ingredients in drugs.
    Type: Grant
    Filed: September 16, 1991
    Date of Patent: November 9, 1993
    Assignee: BASF Aktiengesellschaft
    Inventors: Wilfried Lubisch, Sabine Schult, Rudolf Binder, Manfred Raschack, Roland Reinhardt, Dietmar Seemann
  • Patent number: 5175174
    Abstract: Phenylpiperidinylamines of the formula I ##STR1## where R.sup.1 is --NHSO.sub.2 R.sup.4 or ##STR2## R.sup.2 and R.sup.3 are each, independently of one another, H or C.sub.1 -C.sub.4 -alkyl or together are a (CH.sub.2).sub.n chain with n=4 or 5, andR.sup.4 is C.sub.1 -C.sub.4 -alkyl or phenyl,and the physiologically tolerated salts thereof, and pharmaceutical compositions containing these are described.
    Type: Grant
    Filed: September 16, 1991
    Date of Patent: December 29, 1992
    Assignee: BASF Aktiengesellschaft
    Inventors: Wilfried Lubisch, Sabine Schult, Rudolf Binder, Manfred Raschack, Roland Reinhardt, Dietmar Seemann
  • Patent number: 5118682
    Abstract: p-Hydroxy phenone derivatives of the general formula I ##STR1## where R.sup.1, R.sup.2 and R.sup.3 are identical or different and are methyl, chlorine, bromine and hydrogen, but R.sup.1, R.sup.2 and R.sup.3 are not all H,R.sup.4 and R.sup.5 are identical or different and are H, C.sub.1 -C.sub.4 -alkyl, or OR.sup.6, but R.sup.4 and R.sup.5 are not both H,X is a --CH.dbd.CH--, --CH.sub.2 CH.sub.2 or --CH.sub.2 -- bridge,Y is a straight-chain or branched, saturated or unsaturated C.sub.1 -C.sub.4 bridge, andZ is NR.sup.6 R.sup.7, where R.sup.6 and R.sup.7 are, independently of one another, hydrogen or C.sub.1-4 -alkyl, or Z is a 5- or 6-membered ring with a nitrogen atom in the 1 position and, where appropriate, additionally a second N atom or an O or S atom, the second N atom being substituted by R.sup.7, as well as the physiologically tolerated salts thereof,are used to prepare drugs antiarrhythmic of Vaughan-Williams class III.
    Type: Grant
    Filed: July 12, 1989
    Date of Patent: June 2, 1992
    Assignee: BASF Aktiengesellschaft
    Inventors: Wilfried Lubisch, Manfred Raschack, Gerda von Philipsborn
  • Patent number: 5039701
    Abstract: Benzofuran derivatives of the formula I ##STR1## where R.sup.1 to R.sup.5 and X have the meanings stated in the description, and therapeutic agents containing these derivatives.
    Type: Grant
    Filed: August 19, 1988
    Date of Patent: August 13, 1991
    Assignee: BASF Aktiengesellschaft
    Inventors: Rainer Schlecker, Manfred Raschack, Josef Gries
  • Patent number: 4968717
    Abstract: Compounds of the formula ##STR1## where R.sup.1 to R.sup.7, m, n and p have the meanings stated in the description, and certain derivatives which are p-substituted in the left-hand phenyl ring, are useful for the treatment of disorders.
    Type: Grant
    Filed: May 12, 1989
    Date of Patent: November 6, 1990
    Assignee: BASF Aktiengesellschaft
    Inventors: Liliane Unger, Manfred Raschack, Verena Baldinger, Ferdinand Dengel, Oskar Ehrmann, Hans J. Treiber, Werner Seitz
  • Patent number: 4940780
    Abstract: Basically substituted phenylacetonitriles ##STR1## where R.sup.1 to R.sup.6 and n have the meanings stated in the description, and their preparation are described. The compounds are useful for the treatment of disorders.
    Type: Grant
    Filed: December 10, 1987
    Date of Patent: July 10, 1990
    Assignee: BASF Aktiengesellschaft
    Inventors: Werner Seitz, Liliane Unger, Manfred Raschack, Verena Baldinger, Klaus Ruebsmen, Josef Gries
  • Patent number: 4723039
    Abstract: Phenylacetaldehydes which are substituted by basic groups, of the formula ##STR1## where R.sup.1 to R.sup.8, m and n have the meanings stated in the description, and their preparation are described. The substances are useful for the treatment of disorders.
    Type: Grant
    Filed: December 4, 1986
    Date of Patent: February 2, 1988
    Assignee: BASF Aktiengesellschaft
    Inventors: Werner Seitz, Verena Baldinger, Josef Gries, Dieter Lenke, Manfred Raschack, Klaus Ruebsamen
  • Patent number: 4710496
    Abstract: Novel pyrrol-1-ylphenyldihydropyridazinones of the formula ##STR1## their preparation and their use in the treatment of disorders.
    Type: Grant
    Filed: July 9, 1985
    Date of Patent: December 1, 1987
    Assignee: BASF Aktiengesellschaft
    Inventors: Karl-Heinz Geiss, Bernhard Schmied, Manfred Raschack, Hans-Dieter Lehmann, Josef Gries, Klaus Ruebsamen