Patents by Inventor Manfred Raschack

Manfred Raschack has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 1,7-diphenyl-3-methylaza-7-cyano-8-methylnonane for use in the treatment of diseases
    Patent number: 4596820
    Abstract: 1,7-diphenyl-3-methylaza-7-cyano-8-methylnonane and its antipodes and salts are used for the treatment of diseases.
    Type: Grant
    Filed: December 10, 1984
    Date of Patent: June 24, 1986
    Assignee: BASF Aktiengesellschaft
    Inventors: Manfred Raschack, Horst Kreiskott, Werner Seitz
  • Aminopropanol derivatives of 2-hydroxy-.beta.-phenyl-propiophenones, their preparation and therapeutic agents containing these compounds
    Patent number: 4571409
    Abstract: Novel aminopropanol derivatives of 2-hydroxy-.beta.-phenyl-propiophenones and their physiologically acceptable acid addition compounds, processes for their preparation and therapeutic agents which contain these derivatives and are useful as antiarrhythmic drugs.
    Type: Grant
    Filed: May 13, 1985
    Date of Patent: February 18, 1986
    Assignee: BASF Aktiengesellschaft
    Inventors: Albrecht Franke, Josef Mueller, Helmut Lietz, Walter-Wielant Wiersdorff, Hans-Guenther Hege, Claus D. Mueller, Josef Gries, Dieter Lenke, Gerda von Philipsborn, Manfred Raschack
  • Bispidine derivatives and antiarrhythmic compositions
    Patent number: 4556662
    Abstract: Bispidine derivatives of the formula I ##STR1## where R is hydrogen or amino, and their salts with physiologically tolerated acids. The compounds have antiarrhythmic properties.
    Type: Grant
    Filed: September 30, 1983
    Date of Patent: December 3, 1985
    Assignee: BASF Aktiengesellschaft
    Inventors: Fritz Binnig, Claus D. Mueller, Manfred Raschack, Gerda von Philipsborn
  • Aminopropanol derivatives of 2-hydroxy-.beta.-phenyl-propiophenones, pharmaceutical compositions and use
    Patent number: 4540697
    Abstract: Novel aminopropanol derivatives of 2-hydroxy-.beta.-phenyl-propiophenones and their physiologically acceptable acid addition compounds, processes for their preparation and therapeutic agents which contain these derivatives and are useful as antiarrhythmic drugs.
    Type: Grant
    Filed: May 23, 1984
    Date of Patent: September 10, 1985
    Assignee: BASF Aktiengesellschaft
    Inventors: Albrecht Franke, Josef Muller, Helmut Lietz, Walter-Wielant Wiersdorff, Hans-Gunther Hege, Claus D. Muller, Josef Gries, Dieter Lenke, Gerda von Philipsborn, Manfred Raschack
  • Method of treating cardiac disorders using bispidine derivatives
    Patent number: 4459301
    Abstract: Bispidine derivatives of the formula I ##STR1## where R is hydrogen or amino, and their salts with physiologically tolerated acids. The compounds possess antiarrhythmic properties.
    Type: Grant
    Filed: March 3, 1982
    Date of Patent: July 10, 1984
    Assignee: BASF Aktiengesellschaft
    Inventors: Fritz Binnig, Claus D. Mueller, Manfred Raschack, Gerda von Philipsborn
  • .OMEGA.-Cyano-1, .OMEGA.-diphenyl-azaalkane derivatives, their preparation and drugs containing them
    Patent number: 4438131
    Abstract: .omega.-Cyano-1,.omega.-diphenyl-azaalkane derivatives of the formula I ##STR1## where R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.8, m and n have the meanings given in the description, and salts thereof with physiologically tolerated acids, are useful in treating cardiovascular disorders.
    Type: Grant
    Filed: March 30, 1982
    Date of Patent: March 20, 1984
    Assignee: BASF Aktiengesellschaft
    Inventors: Oskar Ehrmann, Manfred Raschack, Josef Gries, Rolf Kretzschmar, Hans D. Lehmann, Ludwig Friedrich, Dirk Wuppermann, Frank Zimmermann, Werner Seitz, Hans J. Treiber, Ferdinand Dengel, Wolfram Frank, Hans-Georg Kurbjuweit, Claus D. Mueller
  • 4,5-Methano-bufadienolide-rhamnosides, their preparation, and drugs containing these compounds
    Patent number: 4242332
    Abstract: 4,5-methano-bufadienolide-rhamnosides of the formula I ##STR1## where R.sup.1 is hydrogen or alkyl or acyl of 1 to 4 carbon atoms, R.sup.2 and R.sup.3 are identical or different and each is hydrogen or alkyl or acyl of 1 to 4 carbon atoms, or both together are ##STR2## where R.sup.4 and R.sup.5 are identical or different and each is hydrogen or alkyl or alkoxy of 1 or 2 carbon atoms.The novel compounds may be used for counteracting cardiac insufficiency.
    Type: Grant
    Filed: September 6, 1979
    Date of Patent: December 30, 1980
    Assignee: BASF Aktiengesellschaft
    Inventors: Hans P. Albrecht, Gerda von Philipsborn, Hans U. Siebeneick, Manfred Raschack
  • Bispidine derivatives, their preparation, and drugs containing same
    Patent number: 4183935
    Abstract: Bispidine derivatives of the formula ##STR1## where R.sup.1 is H or C.sub.6 H.sub.5, R.sup.2 is H, Cl or CF.sub.3, R.sup.3 is H, F or Cl and X is 0 or 1, and drugs which contain these compounds. The compounds are prepared by condensing N-monobenzylbispidine with appropriately substituted phenylethyl halides or by a Mannich reaction of N-benzylpiperid-4-one with appropriately substituted phenylalkylamines, followed by reduction. They exhibit mainly anti-arrhythmic action.
    Type: Grant
    Filed: June 13, 1978
    Date of Patent: January 15, 1980
    Assignee: BASF Aktiengesellschaft
    Inventors: Fritz Binnig, Ludwig Friedrich, Hans P. Hofmann, Horst Kreiskott, Claus Mueller, Manfred Raschack
  • Alkylenedioxy piperazine derivatives
    Patent number: 4088763
    Abstract: Alkylenedioxy piperazine compounds of the formula ##STR1## and salts thereof with physiologically tolerated acids, useful for the treatment of vascular and cardiac diseases, are disclosed, as are methods for making the compounds and pharmaceutical compositions containing the compounds.
    Type: Grant
    Filed: January 19, 1977
    Date of Patent: May 9, 1978
    Assignee: Knoll A.G. Chemische Fabriken
    Inventors: Richard Cyrus, Manfred Raschack
  • N-Benzhydryl-3-methyl-3-(dialkoxy)benzyl-piperazines
    Patent number: 4079137
    Abstract: Piperazine compounds of the formula ##STR1## and salts thereof with physiologically tolerable acids useful for the treatment of vascular and cardiac diseases, are disclosed, as are methods for making the compounds and pharmaceutical compositions containing the compounds.
    Type: Grant
    Filed: January 19, 1977
    Date of Patent: March 14, 1978
    Assignee: Knoll A.G. Chemische Fabriken
    Inventors: Richard Cyrus, Manfred Raschack
  • 3-(3,4-Dialkoxy-benzyl)-3-methyl-piperazines
    Patent number: 4031216
    Abstract: Cardioactive 3-methyl-3-(3,4-dialkoxybenzyl)-piperazine compounds of the formula ##STR1## and their salts with physiologically tolerable acids; methods for making the same; pharmaceutical compositions containing the compounds as an active ingredient; and methods of treating cardiac diseases such as arrhythmia with said compounds.
    Type: Grant
    Filed: August 31, 1976
    Date of Patent: June 21, 1977
    Assignee: Knoll A.G. Chemische Fabriken
    Inventors: Richard Cyrus, Manfred Raschack
  • Isoquinoline compounds
    Patent number: 4013663
    Abstract: Isoquinoline compounds having .beta.-receptor blocking activity, particularly for the heart, and having the formula ##STR1## and salts thereof with physiologically tolerable acids, wherein R.sub.1 is hydrogen or methyl, R.sub.2 is hydrogen or lower alkyl, R.sub.3 is hydrogen or methoxy, and R.sub.4 is isopropyl or tertiary butyl. A method for making such compounds. Pharmaceutical compositions containing such compounds.
    Type: Grant
    Filed: October 30, 1975
    Date of Patent: March 22, 1977
    Assignee: Knoll A.G. Chemische Fabriken
    Inventors: Albert Westermann, Frank Zimmermann, Dirk Wuppermann, Ludwig Friedrich, Manfred Raschack
  • Anti-arrhythmic agents
    Patent number: 4010282
    Abstract: Methods of treating cardiac arrhythmia by the oral or parenteral administration of N,N'-dibenzyl-alkylene diamine compounds of the formula ##STR1## or salts thereof with pharmaceutically acceptable acids, wherein A, B, D, and E are hydrogen, chlorine, or methoxy, and n is 2, 3, or 4; therapeutic compositions containing these anti-arrhythmic agents in combination with a pharmaceutical excipient.
    Type: Grant
    Filed: June 25, 1975
    Date of Patent: March 1, 1977
    Assignee: Knoll A.G. Chemische Fabriken
    Inventors: Fritz Binnig, Manfred Raschack
  • Piperazine compounds
    Patent number: 3996360
    Abstract: Cardioactive 3-methyl-3-(3,4-dialkoxybenzyl)-piperazine compounds of the formula ##STR1## and their salts with physiologically tolerable acids; methods for making the same; pharmaceutical compositions containing the compounds as an active ingredient; and methods of treating cardiac diseases such as arrhythmia with said compounds.
    Type: Grant
    Filed: July 31, 1975
    Date of Patent: December 7, 1976
    Assignee: Knoll A.G. Chemische Fabriken
    Inventors: Richard Cyrus, Manfred Raschack
  • Cardioactive bispidones and bispidines
    Patent number: 3962449
    Abstract: Cardioactive bispidones and bispidines of the formula ##SPC1##Wherein R is =C=O or --CH.sub.2 -- and R' and R" are alkyl mono- or di-substituted by phenyl, made by a Mannich reaction from formaldehyde, piperidones of the formula ##SPC2##And amines of the formula R"--NH.sub.2.
    Type: Grant
    Filed: June 10, 1975
    Date of Patent: June 8, 1976
    Assignee: Knoll A.G. Chemische Fabriken
    Inventors: Fritz Binnig, Manfred Raschack, Hans-Joerg Treiber