Patents by Inventor Manfred Reiter

Manfred Reiter has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANIMAL PROTEIN-FREE MEDIA FOR CULTIVATION OF CELLS
    Publication number: 20080009040
    Abstract: The present invention relates to animal protein-free cell culture media comprising polyamines and a plant- and/or yeast-derived hydrolysate. The invention also relates to animal protein-free culturing processes, wherein cells can be cultivated, propagated and passaged without adding supplementary animal proteins in the culture medium. These processes are useful in cultivating cells, such as recombinant cells or cells infected with a virus, and for producing biological products by cell culture processes.
    Type: Application
    Filed: September 20, 2007
    Publication date: January 10, 2008
    Applicant: Baxter Healthcare Corporation
    Inventors: Leopold Grillberger, Manfred Reiter, Wolfgang Mundt, Friedrich Dorner
  • Method of isolation and purification of trypsin from pronase protease and use thereof
    Publication number: 20070249015
    Abstract: The present invention provides methods of isolation and purification of Streptomyces griseus trypsin (SGT) from PRONASE protease mixture in a single affinity chromatography step and uses of the purified SGT.
    Type: Application
    Filed: April 20, 2007
    Publication date: October 25, 2007
    Applicant: Baxter Healthcare S.A.
    Inventors: Artur Mitterer, Christa Tauer, Manfred Reiter, Wolfgang Mundt
  • Oligopeptide-free cell culture media
    Publication number: 20070212770
    Abstract: The present invention relates to oligopeptide-free cell culture media comprising at least 0.5 mg/L of a polyamine and to methods for cultivating cells in said oligopeptide-free cell culture media comprising at least 0.5 mg/L of a polyamine. The invention also relates to methods for expressing at least one protein in a medium comprising at least 0.5 mg/L of a polyamine and to methods for producing at least one virus in a medium comprising at least 0.5 mg/L of a polyamine.
    Type: Application
    Filed: January 3, 2007
    Publication date: September 13, 2007
    Applicants: Baxter International Inc., Baxter Healthcare, S.A.
    Inventors: Leopold Grillberger, Manfred Reiter, Wolfgang Mundt, Artur Mitterer
  • Recombinant cell clones having increased stability and methods of making and using the same
    Publication number: 20070161079
    Abstract: Disclosed are a stable recombinant cell clones which are stable in serum- and protein-free medium for at least 40 generations, a biomass obtained by multiplying the stable cell clone under serum- and protein-free culturing conditions, and a method of preparing recombinant proteins by means of the biomass. Furthermore, the invention relates to a method of recovering stable recombinant cell clones.
    Type: Application
    Filed: July 7, 2006
    Publication date: July 12, 2007
    Applicant: Baxter Aktiengesellschaft
    Inventors: Manfred Reiter, Wolfgang Mundt, Friedrich Dorner
  • Enveloped virus vaccine and method for production
    Publication number: 20070141617
    Abstract: The present invention provides methods of production of a purified enveloped virus antigen. In particular, it provides purified Ross River Virus (RRV) antigens, and vaccines comprising purified, inactivated Ross River Virus (RRV) antigen.
    Type: Application
    Filed: January 24, 2007
    Publication date: June 21, 2007
    Applicant: Baxter Healthcare S.A.
    Inventors: Otfried Kistner, Manfred Reiter, Axel Bruehmann, Noel Barrett, Wolfgang Mundt, Friedrich Dorner
  • Use of purified trypsin for production of a biomass of cells and viral propagation
    Patent number: 7223595
    Abstract: The present invention provides methods of isolation and purification of Streptomyces griseus trypsin (SGT) from PRONASE protease mixture in a single affinity chromatography step and uses of the purified SGT.
    Type: Grant
    Filed: September 17, 2004
    Date of Patent: May 29, 2007
    Assignee: Baxter Healthcare S.A.
    Inventors: Artur Mitterer, Christa Tauer, Manfred Reiter, Wolfgang Mundt
  • Enveloped virus vaccine and method for production
    Patent number: 7195905
    Abstract: The present invention provides methods of production of a purified enveloped virus antigen. In particular, it provides purified Ross River Virus (RRV) antigens, and vaccines comprising purified, inactivated Ross River Virus (RRV) antigen.
    Type: Grant
    Filed: December 10, 2001
    Date of Patent: March 27, 2007
    Assignee: Baxter Healthcare S.A.
    Inventors: Otfried Kistner, Manfred Reiter, Axel Bruehmann, Noel Barrett, Wolfgang Mundt, Friedrich Dorner
  • Inactivation of a pathogen in a sample by a treatment with formalin and UV light
    Publication number: 20060270017
    Abstract: The present invention relates to a method for inactivating virus in a sample by treating a virus containing sample with an effective concentration of formalin and by treating the sample with an effective dose of UV light in a flow-through apparatus.
    Type: Application
    Filed: May 26, 2005
    Publication date: November 30, 2006
    Inventors: Manfred Reiter, Wolfgang Mundt, Noel Barrett, Otfried Kistner
  • Recombinant cell clones having increased stability and methods of making and using the same
    Patent number: 7094574
    Abstract: Disclosed are a stable recombinant cell clones which are stable in serum- and protein-free medium for at least 40 generations, a biomass obtained by multiplying the stable cell clone under serum- and protein-free culturing conditions, and a method of preparing recombinant proteins by means of the biomass. Furthermore, the invention relates to a method of recovering stable recombinant cell clones.
    Type: Grant
    Filed: May 6, 2005
    Date of Patent: August 22, 2006
    Assignee: Baxter Aktiengesellschaft
    Inventors: Manfred Reiter, Wolfgang Mundt, Friedrich Dorner
  • Animal protein-free media for cultivation of cells
    Publication number: 20060094104
    Abstract: The present invention relates to animal protein-free cell culture media comprising polyamines and a plant and/or yeast-derived hydrolysate. The invention also relates to animal protein-free culturing processes, wherein cells can be cultivated, propagated and passaged without adding supplementary animal proteins in the culture medium. These processes are useful in cultivating cells, such as recombinant cells or cells infected with a virus, and for producing biological products by cell culture processes.
    Type: Application
    Filed: October 29, 2004
    Publication date: May 4, 2006
    Inventors: Leopold Grillberger, Manfred Reiter, Wolfgang Mundt, Friedrich Dorner
  • Method for large scale production of virus antigen
    Patent number: 6951752
    Abstract: The present invention provides improved methods of production of viral antigen on a culture of adherent cells bound to a microcarrier, wherein the methods provide for increased viral antigen yield per culture medium volume. The invention is also directed to a cell culture biomass of adherent cells having increased cell density and microcarrier concentration compared to the respective confluent cell culture.
    Type: Grant
    Filed: December 10, 2001
    Date of Patent: October 4, 2005
    Assignee: Bexter Healthcare S.A.
    Inventors: Manfred Reiter, Wolfgang Mundt
  • Recombinant cell clones having increased stability and methods of making and using the same
    Publication number: 20050196843
    Abstract: Disclosed are a stable recombinant cell clones which are stable in serum- and protein-free medium for at least 40 generations, a biomass obtained by multiplying the stable cell clone under serum- and protein-free culturing conditions, and a method of preparing recombinant proteins by means of the biomass. Furthermore, the invention relates to a method of recovering stable recombinant cell clones.
    Type: Application
    Filed: May 6, 2005
    Publication date: September 8, 2005
    Applicants: Baxter Aktiengesellschaft, Baxter Healthcare Corporation
    Inventors: Manfred Reiter, Wolfgang Mundt, Friedrich Dorner
  • Recombinant cell clones having increased stability and methods of making and using the same
    Patent number: 6936441
    Abstract: Disclosed are a stable recombinant cell clones which are stable in serum- and protein-free medium for at least 40 generations, a biomass obtained by multiplying the stable cell clone under serum- and protein-free culturing conditions, and a method of preparing recombinant proteins by means of the biomass. Furthermore, the invention relates to a method of recovering stable recombinant cell clones.
    Type: Grant
    Filed: June 12, 2002
    Date of Patent: August 30, 2005
    Assignee: Baxter Aktiengesellschaft
    Inventors: Manfred Reiter, Wolfgang Mundt, Friedrich Dorner
  • Large scale productions of virus antigen
    Publication number: 20050181495
    Abstract: The present invention provides improved methods of production of viral antigen on a culture of adherent cells bound to a microcarrier, wherein the methods provide for increased viral antigen yield per culture medium volume. The invention is also directed to a cell culture biomass of adherent cells having increased cell density and microcarrier concentration compared to the respective confluent cell culture.
    Type: Application
    Filed: March 17, 2005
    Publication date: August 18, 2005
    Applicant: Baxter Healthcare S.A.
    Inventors: Manfred Reiter, Wolfgang Mundt
  • Method of isolation and purification of trypsin from pronase protease and use thereof
    Publication number: 20050069534
    Abstract: The present invention provides methods of isolation and purification of Streptomyces griseus trypsin (SGT) from pronase in a single affinity chromatography step and uses of the purified SGT.
    Type: Application
    Filed: September 17, 2004
    Publication date: March 31, 2005
    Applicant: Baxter Healthcare S.A.
    Inventors: Artur Mitterer, Christa Tauer, Manfred Reiter, Wolfgang Mundt
  • Method of large scale production of Hepatitis A virus
    Patent number: 6855535
    Abstract: The present invention provides methods of large scale production of Hepatitis A Virus (HAV) on VERO cells bound to microcarrier. The invention also provides for methods of isolation of HAV from the cell culture supernatant of HAV infected VERO cells.
    Type: Grant
    Filed: December 10, 2001
    Date of Patent: February 15, 2005
    Assignee: Baxter Healthcare S.A.
    Inventors: Heidi Meyer, Manfred Reiter, Wolfgang Mundt, Noel Barrett, Friedrich Dorner
  • Method of isolation and purification of trypsin from pronase protease and use thereof
    Patent number: 6830917
    Abstract: The present invention is directed to methods of isolation and purification of Streptomyces griseus trypsin (SGT) from PRONASE protease in a single affinity chromatography step and uses of the purified SGT.
    Type: Grant
    Filed: December 10, 2001
    Date of Patent: December 14, 2004
    Assignee: Baxter Healthcare S.A.
    Inventors: Artur Mitterer, Christa Tauer, Manfred Reiter, Wolfgang Mundt
  • Animal protein free media for cultivation of cells
    Publication number: 20040077086
    Abstract: The present invention relates to animal protein free cell culture media comprising a combination of non-animal derived peptides derived from soy hydrolysate and yeast hydrolysate. The invention also provides an animal protein free culture process, wherein cells are cultivated, propagated and passaged without animal-derived components. This process is useful for cultivating cells, such as recombinant cells or cells infected with a virus, and for production biological products by cell culture processes under conditions devoid of animal protein components.
    Type: Application
    Filed: July 8, 2003
    Publication date: April 22, 2004
    Inventors: Manfred Reiter, Wolfgang Mundt, Leopold Grillberger, Barbara Kraus
  • Medium for the protein-free and serum-free cultivation of cells
    Publication number: 20030203448
    Abstract: A medium is described for the protein-free and serum-free cultivation of cells, especially mammalian cells, whereby the medium contains a proportion of soy hydrolysate.
    Type: Application
    Filed: April 1, 2003
    Publication date: October 30, 2003
    Inventors: Manfred Reiter, Wolfgang Mundt, Friedrich Dorner, Leopold Grillberger, Artur Mitterer
  • Method of isolation and purification of trypsin from pronase and use thereof
    Publication number: 20030124650
    Abstract: The present invention provides methods of isolation and purification of Strepomyces griseus trypsin (SGT) from pronase in a single affinity chromatography step and uses of the purified SGT.
    Type: Application
    Filed: December 10, 2001
    Publication date: July 3, 2003
    Inventors: Artur Mitterer, Christa Tauer, Manfred Reiter, Wolfgang Mundt