Patents by Inventor Manik Reddy Pullagurla

Manik Reddy Pullagurla has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL PROCESS FOR THE PREPARATION OF PASIREOTIDE
    Publication number: 20180186829
    Abstract: The present invention relates to a novel process for the preparation of Pasireotide of formula 11 [Cyclo [Phe-{4-(OCO—NH—CH2—CH2—NH2)) Pro}-Phg-DTrp-Lys-Tyr(Bzl)]]. The invention also relates to a novel intermediate compound of formula 8 and process thereof which is used for preparation of compound of formula 11.
    Type: Application
    Filed: June 22, 2016
    Publication date: July 5, 2018
    Inventors: Manik Reddy PULLAGURLA, Radha NAGARAPU, Jagadeesh Babu RANGISETTY
  • Process for the synthesis of melphalan and the hydrochloride salt
    Patent number: 9963422
    Abstract: The present invention relates to an improved process for the preparation of Melphalan, more specifically the invention relates to an efficient process for the preparation of substantially pure Melphalan hydrochloride (I).
    Type: Grant
    Filed: March 4, 2014
    Date of Patent: May 8, 2018
    Assignee: Biophore India Pharmaceuticals PVT. Ltd.
    Inventors: Manik Reddy Pullagurla, Jagadeesh Babu Rangisetty, Mecheril Valsan Nandakumar, Madhava Reddy Vedururi, Sreenu Samireddi
  • Process for the Preparation of (S)-4-Methyl-N-((S)-1-(((S)-4-Methyl-1-((R)-2-Methyloxiran-2-YL)-1-OXO Pentan-2-YL) Amino)-1-OXO-3-Phenylpropan-2-YL)-2-((S)-2-(2-Morpholinoacetamido)-4-Phenylbutanamido) Pentanamide
    Publication number: 20170298093
    Abstract: Novel methods for preparation of Carfilzomib and intermediates thereof with high stereo selection are reported. The synthetic procedures result in substantially pure Carfilzomib (I).
    Type: Application
    Filed: August 29, 2015
    Publication date: October 19, 2017
    Applicant: Biophore India Pharmaceuticals Pvt. Ltd
    Inventors: Manik Reddy Pullagurla, Jagadeesh Babu Rangisetty, Mecheril Valsan Nanda Kumar, Surya Bala Subrahmanyam Pendyala, Bhaskar Reddy Pitta
  • Polymorph of regadenoson
    Patent number: 9624258
    Abstract: The invention provides a novel polymorph of Regadenoson. More particularly, the invention provides propylene glycol solvate of Regadenoson. The invention also provides a process for the preparation of propylene glycol solvate of Regadenoson.
    Type: Grant
    Filed: May 28, 2014
    Date of Patent: April 18, 2017
    Assignee: Biophore India Pharmaceuticals PVT. Ltd.
    Inventors: Jagadeesh Babu Rangisetty, Manik Reddy Pullagurla, Mecheril Valsan Nandakumar, Dokula Neelam Naidu
  • AN IMPROVED PROCESS FOR THE SYNTHESIS OF DIMETHYL FUMARATE
    Publication number: 20170096384
    Abstract: The present invention describes an improved process for the industrial scale production of dimethyl fumarate. The process involves a one-pot ring opening reaction of maleic anhydride to monomethyl maleate and isomerization into the corresponding monomethyl fumarate in presence of a Lewis acid. Finally the mono methyl fumarate was converted into the dimethyl fumarate by an acid catalyzed esterification reaction.
    Type: Application
    Filed: December 29, 2014
    Publication date: April 6, 2017
    Inventors: Manik Reddy Pullagurla, Jagadeesh Babu Rangisetty, Mecheril Vaisan Nandakumar, Nagarapu Radha
  • Process for the preparation of (1-{9-[(4S, 2R, 3R, 5R)-3, 4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl)-6-aminopurin-2-yl}pyrazole-4-yl)-N-methylcarboxamide
    Patent number: 9580457
    Abstract: The present invention relates to a novel process for the preparation of (1-{9-[(4S,2R,3R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl)-6-aminopurin-2-yl}pyrazole-4-yl)-N-methylcarboxamide.
    Type: Grant
    Filed: October 28, 2013
    Date of Patent: February 28, 2017
    Assignee: Biophore India Pharmaceuticals PVT. Ltd.
    Inventors: Manik Reddy Pullagurla, Jagadeesh Babu Rangisetty, Mecheril Valsan Nandakumar
  • Process for the Synthesis of Dabigatran Etexilate and Its Intermediates
    Publication number: 20170050948
    Abstract: The present invention describes an improved process for the preparation of Dabigatran Etexilate (Formula-VII) or it's pharmaceutically acceptable salt for the treatment of thrombosis, cardiovascular diseases etc. and intermediates involved in the synthesis.
    Type: Application
    Filed: October 12, 2016
    Publication date: February 23, 2017
    Inventors: Manik Reddy PULLAGURLA, Jagadeesh Babu RANGISETTY, Mecheril Valsan NANDAKUMAR
  • Process for the synthesis of dabigatran and its intermediates
    Patent number: 9533971
    Abstract: The present invention describes an improved process for the preparation of Dabigatran Etexilate (Formula-VII) or it's pharmaceutically acceptable salt for the treatment of thrombosis, cardiovascular diseases etc. and intermediates involved in the synthesis.
    Type: Grant
    Filed: October 28, 2013
    Date of Patent: January 3, 2017
    Assignee: Biophore India Pharmaceuticals PVT. Ltd
    Inventors: Manik Reddy Pullagurla, Jagadeesh Babu Rangisetty, Mecheril Valsan Nandakumar
  • Novel Polymorph of Regadenoson
    Publication number: 20160115191
    Abstract: The invention provides a novel polymorph of Regadenoson. More particularly, the invention provides propylene glycol solvate of Regadenoson. The invention also provides a process for the preparation of propylene glycol solvate of Regadenoson.
    Type: Application
    Filed: May 28, 2014
    Publication date: April 28, 2016
    Inventors: Jagadeesh Babu RANGISETTY, Manik Reddy PULLAGURLA, Mecheril Valsan NANDAKUMAR, Dokula Neelam NAIDU
  • An Improved Process for the Synthesis of Melphalan and the Hydrochloride Salt
    Publication number: 20160016889
    Abstract: The present invention relates to an improved process for the preparation of Melphalan, more specifically the invention relates to an efficient process for the preparation of substantially pure Melphalan hydrochloride (I).
    Type: Application
    Filed: March 4, 2014
    Publication date: January 21, 2016
    Inventors: Manik Reddy PULLAGURLA, Jagadeesh Babu RANGISETTY, Mecheril Valsan NANDAKUMAR, Madhava Reddy VEDURURI, Sreenu SAMIREDDI
  • Novel Process for the Preparation of (1-pyrazole-4-yl)-N-methylcarboxamide
    Publication number: 20150353593
    Abstract: The present invention relates to a novel process for the preparation of (1-{9-[(4S,2R,3R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl)-6-aminopurin-2-yl}pyrazole-4-yl)-N-methylcarboxamide.
    Type: Application
    Filed: October 28, 2013
    Publication date: December 10, 2015
    Inventors: Manik Reddy PULLAGURLA, Jagadeesh Babu RANGISETTY, Mecheril Valsan NANDAKUMAR
  • Process for the Synthesis of Etravirine and Its Intermediates
    Publication number: 20150336900
    Abstract: The invention discloses the synthesis of Etravirine via intermediate 4-((4-amino-5-bromo-6-chloropyrimidin-2-yl) amino)benzonitrile and process for the preparation of Etravirine of the formula-I.
    Type: Application
    Filed: October 28, 2013
    Publication date: November 26, 2015
    Applicant: Biophore India Pharmaceuticals PVT. Ltd.
    Inventors: Manik Reddy PULLAGURLA, Jagadeesh Babu RANGISETTY, Mecheril Valsan NANDAKUMAR
  • Process for the Synthesis of Dabigatran and Its Intermediates
    Publication number: 20150246900
    Abstract: The present invention describes an improved process for the preparation of Dabigatran Etexilate (Formula-I), a pharmaceutically acceptable salt for the treatment of thromboses, cardiovascular diseases etc. and intermediates involved in the synthesis.
    Type: Application
    Filed: October 28, 2013
    Publication date: September 3, 2015
    Applicant: Biophore India Pharmeuticals PVT. Ltd.
    Inventors: Manik Reddy Pullagurla, Jagadeesh Babu Rangisetty, Mecheril Valsan Nandakumar
  • Process for the preparation of taurolidine and its intermediates thereof
    Patent number: 8952148
    Abstract: The present invention relates to a process for the preparation of substantially pure Taurolidine.
    Type: Grant
    Filed: November 18, 2011
    Date of Patent: February 10, 2015
    Assignee: Biophore India Pharmaceuticals Pvt Ltd
    Inventors: Manik Reddy Pullagurla, Jagadeesh Babu Rangisetty, Neelam Naidu Dokula
  • Process for the preparation of eletriptan
    Patent number: 8633239
    Abstract: The present invention relates to a novel process for the preparation of (R)-3-((1-methylpyrrolidin-2-yl)methyl)-5-(2-(phenylsulfonyl)ethyl)-1H-indole and its intermediates thereof.
    Type: Grant
    Filed: October 29, 2009
    Date of Patent: January 21, 2014
    Assignee: Biophore India Pharmaceuticals Private Limited
    Inventors: Manik Reddy Pullagurla, Jagadeesh Babu Rangisetty, Neelam Naidu, Nagaraju Maddela, Radha Nagarapu, Pulla Rao Polagani
  • Process for Preparation of Intermediates of Bendamustine
    Publication number: 20130317234
    Abstract: The present invention relates to a process for the preparation of 4-{5-{Bis-(2-hydroxyl-ethyl)-amino}-1-methyl-1H-Benzoimidazol-2yl}-butyric acid alkyl ester of formula IV, a key intermediate in the process for the preparation of Bendamustine HCl (I)
    Type: Application
    Filed: July 14, 2011
    Publication date: November 28, 2013
    Applicant: BIOPHORE INDIA PHARMACEUTICALS PVT. LTD
    Inventors: Manik Reddy Pullagurla, Jagadeesh Babu Rangisetty, S. I. Davis Presley, Radha Nagarapu
  • PROCESS FOR THE PREPARATION OF TAUROLIDINE AND ITS INTERMEDIATES THEREOF
    Publication number: 20130237700
    Abstract: The present invention relates to a process for the preparation of substantially pure Taurolidine.
    Type: Application
    Filed: November 18, 2011
    Publication date: September 12, 2013
    Applicant: BIOPHORE INDIA PHARMACEUTICALS PVT. LTD.
    Inventors: Manik Reddy Pullagurla, Jagadeesh Babu Rangisetty, Neelam Naidu Dokula
  • Formulations of Temozolomide for Parenteral Administration
    Publication number: 20120283304
    Abstract: The present invention relates to a parenteral formulation of Temozolomide comprising an excipient selected from the group consisting of bulking agents, buffers, pH adjusting agents, with the proviso that the formulation is free of dissolution enhancing agents.
    Type: Application
    Filed: December 22, 2010
    Publication date: November 8, 2012
    Applicant: SAHAJ LIFE SCIENCES PVT. LTD.
    Inventors: Manik Reddy Pullagurla, Jagadeesh Babu Rangisetty
  • NOVEL PROCESS FOR THE PREPARATION OF ELETRIPTAN
    Publication number: 20110207943
    Abstract: The present invention relates to a novel process for the preparation of (R)-3-((1-methylpyrrolidin-2-yl)methyl)-5-(2-(phenylsulfonyl)ethyl)-1H-indole and its intermediates thereof.
    Type: Application
    Filed: October 29, 2009
    Publication date: August 25, 2011
    Inventors: Manik Reddy Pullagurla, Jagadeesh Babu Rangisetty, Neelam Naidu, Nagaraju Maddela, Radha Nagarapu, Pulla Rao Polagani