Abstract: Provided herein are methods and systems configured to analyze exposomic features of subjects undergoing space travel.

Abstract: Present disclosure generally relates to devices and methods for conveying small amounts of fluids, and particularly relates to apparatus and method for scalable fluid delivery to achieve minimal motion of syringe plunger using multiple kinematic chain elements/pathways actuated by a single Motion Actuating Device (MAD). The scalable fluid delivery apparatus provides first kinematic pathway corresponding to high linear resolution mode of Piston Drive Member (PDM) and second kinematic pathway corresponding to low linear resolution mode of PDM. The first kinematic pathway includes final step of delivering fluid comprised in syringe, upon pushing plunger, and second kinematic pathway includes final step of performing forward motion or reverse motion of PDM. Forward motion, or reverse motion of PDM is for priming barrel and removable fluid delivery tube or to revert the PDM to an initial position, respectively, or to deliver the fluid.

Abstract: A memory circuit includes first and second write lines and memory segments. A first driver includes, between power and reference nodes, a PMOS transistor and a first inverter including an input coupled to a first driver first input and an output coupled to the first write line, and a second inverter coupled between the PMOS transistor gate and a first driver second input. A second driver includes, between the power and reference nodes, a PMOS transistor and a third inverter including an input coupled to a second driver first input and an output coupled to the second write line, and a fourth inverter coupled between the PMOS transistor gate and a second driver second input. Each of the first driver first input and second driver second input receives a first data signal, and each of the first driver second input and second driver first input receives a second data signal.

Abstract: A memory circuit includes first and second memory segments coupled to first and second write lines, and first and second write line circuits coupled to the first and second write lines and configured to receive first and second data signals. The first and second data signals have complementary low and high logical states during a write operation to the first or second memory segment, and each of the first and second data signals has the low logical state during a masked write operation to the first or second memory segment. The first and second write line circuits output, to the first and second write lines, first and second write line signals responsive to the first and second data signals during the write operation and float the first and second data lines during the masked write operation.

Abstract: Disclosed herein a method, tin Electrical Stimulation System (ESS) 101, and an electronic wearable unit 301 for controlling an electrical stimulation 113 to a pelvic region of a subject 103. The electronic wearable unit 301 comprises a non-skin contacting outer surface 307, a skin contacting inner surface 305 with a crotch part for removably attaching a urine collecting device 309, and the ESS 101 removably placed within a space bounded by the outer surface 307 and the inner surface 305. An input 105 for initiating a session is received. Further, at least one of, an activity level 107 of muscles in and around the pelvic region, an orientation 109 of one or more of the muscles, and a body posture 111 of the subject 103 is received, throughout the session. Based on the determination, the electrical stimulation 113 to the pelvic region of the subject 103 is controlled.

Abstract: The present disclosure relates to a system for additive manufacturing. The system includes a frame, a CNC bed configured with the frame. A metal dispensing mechanism configured to eject metal droplets on the CNC bed. The metal dispensing mechanism is configured to controllably move with respect to the CNC bed for manufacturing the object. The metal dispensing mechanism includes a first nozzle, functionally configured with the CNC bed, for controllably dispensing the metal droplets on the CNC bed, and the nozzle is fluidically configured with a reservoir having the metal. A piston configured with the reservoir, and the piston is configured to push the molten metal from the reservoir such the molten metal is released from the reservoir towards the first nozzle. The piston is made of thermally insulating material, and a transducer configured with the piston to facilitate mechanical jerking of the piston for facilitating the pushing of the molten metal from the reservoir.

Abstract: Provided are herein are devices, systems, and methods of measuring the topography of a biological surface and deriving a probabilistic prediction of the presence or lack thereof phenotypic feature.

Abstract: The present disclosure provides methods and systems for predicting a subject's diagnostic status with respect to a disease or disorder. The method may comprise exposing a biological sample of the subject to a laser, acquiring a plurality of Raman spectra from the exposed biological sample, processing the plurality of Raman spectra to generate a spatial map of the plurality of Raman spectra, and predicting a subject's diagnostic status with respect to disease or disorder based at least in part on the spatial map of the plurality of Raman spectra. The analyzing may comprise determining temporal dynamics of underlying biological processes.

Abstract: The present disclosure provides methods and systems for predicting a subjects diagnostic status with respect to a disease or disorder. The method may comprise staining a tooth, hair, or nail sample of the subject to produce a stained tooth sample, analyzing a fluorescence intensity spatially across the stained tooth, hair, or nail sample, and predicting a subjects diagnostic status with respect to a disease or disorder based at least in part on the analysis of the fluorescence intensity.

Abstract: A memory circuit includes first and second memory segments coupled to first and second write lines, and first and second write line circuits coupled to the first and second write lines and configured to receive first and second data signals. The first and second data signals have complementary low and high logical states during a write operation to the first or second memory segment, and each of the first and second data signals has the low logical state during a masked write operation to the first or second memory segment. The first and second write line circuits output, to the first and second write lines, first and second write line signals responsive to the first and second data signals during the write operation and float the first and second data lines during the masked write operation.

Abstract: Computer-implemented exposomics systems are provided that include an exposome biochemical signature database, comprising a corresponding plurality of exposomic features for each subject in a plurality of subjects, and an intervention outcome database, comprising information on intervention outcome information for at least one phase of at least one intervention of at least one subject of the plurality of subjects. An association software module determines an association between the corresponding plurality of exposomic features and the intervention outcome information. A recommendation software module provides an intervention recommendation for the at least one subject based at least in part on the corresponding plurality of exposomic features, the intervention outcome information, and the association between the corresponding plurality of exposomic features, the clinical phenotype information, and the intervention outcome information for the at least one subject.

Abstract: A write line circuit includes a power supply node configured to carry a power supply voltage level, a reference node configured to carry a reference voltage level, an output node, first and second switching devices coupled in series between the output node and the power supply node, and a third switching device directly coupled to each of the output node and the reference node. The first switching device is configured to selectively couple the output node to the second switching device responsive to a first data signal, the second switching device is configured to selectively couple the first switching device to the power supply node responsive to a second data signal, and the third switching device is configured to selectively couple the output node to the reference node responsive to the first data signal.

Abstract: Various circuit board embodiments are disclosed. In one aspect, an apparatus is provided that includes a circuit board and a first phase change material pocket positioned on or in the circuit board and contacting a surface of the circuit board.

Abstract: A method for evaluating a subject for a biological condition associated with metal metabolism includes sampling positions along a biological sample of the subject to obtain several ion samples. Each ion sample corresponds to a position on the biological sample and each position represents an amount of growth of the biological sample. The obtained ions are analyzed with a mass spectrometer thereby obtaining a plurality of traces. Each such trace represents a concentration of a corresponding elemental isotope, in a plurality of elemental isotopes, over time. A set of features is derived from the traces. Each feature is determined by a variation of a single isotope or a combination of isotopes in the plurality of traces. The set of features is inputted into a trained classifier to obtain a probability that the subject has the biological condition associated with metal metabolism.

Abstract: A telecommunications service provider's real time analysis system analyzes communications data to detect potentially fraudulent communications data, where the analysis is performed in real time in the routing path of the communications data. The communications data may include calls (e.g., SS7, VoIP, etc. based calls) and messages (e.g., SMS, MMS, etc.). The real time analysis system rejects potentially fraudulent communications data and non-fraudulent communications data in order to be used in real time in the routing path of the communications data. A rejection by the real time analysis system may cause non-fraudulent communications data to still be sent to the intended destination of the communications data. The real time analysis system can be in the routing path of the communications data without further routing non-fraudulent communications data traffic to the next appropriate hop in the routing path.

Abstract: Various circuit board embodiments are disclosed. In one aspect, an apparatus is provided that includes a circuit board and a first phase change material pocket positioned on or in the circuit board and contacting a surface of the circuit board.

Abstract: A plurality of thermal electric cooler (TEC) elements are formed in a TEC grid structure. Control logic dynamically varies a supply current supplied to each TEC element (or group of TEC elements) in the TEC grid based on changes in power density respectively associated with areas cooled by each of the TEC elements or group of TEC elements.

Abstract: A semiconductor memory device comprising a plurality of memory cells configured to store digital data and an input multiplexer configured to enable the selection of a particular memory cell from the plurality of memory cells. The semiconductor memory device further comprises a read/write driver circuit configured to read data from the selected memory cell and write data to the selected memory cell, and a write logic block configured to provide logical control to the read/write driver circuit for writing data to the selected of memory cell. The read/write driver circuit may be coupled to the read/write input multiplexer by a data line and an inverted data line and the read and the write operations to the selected memory cell occur over the same data line and inverted data line.