Abstract: Exemplary methods and systems for managing an e-reader interface are disclosed herein. An exemplary method includes an e-reader interface management system directing an e-reader device to display a plurality of graphical objects representative of a plurality of segments of an e-publication and arranged in a plurality of overlapping rows, detecting that a user has accessed a particular segment within the plurality of segments and represented by a particular graphical object within the plurality of graphical objects, and dynamically altering at least one display attribute associated with the particular graphical object to indicate that the particular segment has been accessed by the user. Corresponding methods and systems are also disclosed.

Abstract: Exemplary methods and systems for managing an e-reader interface are disclosed herein. An exemplary method includes an e-reader interface management system directing an e-reader device to display a plurality of graphical objects representative of a plurality of segments of an e-publication, detecting a user interaction with a graphical object within the plurality of graphical objects and representative of a segment within the plurality of segments, and directing the e-reader device to remove at least one other graphical object within the graphical objects from the display of the graphical objects, wherein the at least one other graphical object is representative of at least one other segment within the plurality of segments that is unrelated to the segment. Corresponding methods and systems are also disclosed.

Abstract: Exemplary methods and systems for managing an e-reader interface are disclosed herein. An exemplary method includes an e-reader interface management system directing an e-reader device to display a plurality of graphical objects representative of a plurality of segments of an e-publication and arranged in a plurality of overlapping rows, detecting that a user has accessed a particular segment within the plurality of segments and represented by a particular graphical object within the plurality of graphical objects, and dynamically altering at least one display attribute associated with the particular graphical object to indicate that the particular segment has been accessed by the user. Corresponding methods and systems are also disclosed.

Abstract: A strategy for inducing immune T lymphocytes to respond in such a fashion to their target antigen at first exposure so as to enable them to mount a response of greater magnitude upon any subsequent exposure to the same target is provided. The strategy involves exposure of T cells or animals being immunized to the commonly used phosphodiesterase inhibitor drug, pentoxifylline (POX/PF/Trental), during immune priming. Evidence is provided showing that such exposure leads to enhancement of immune T cells responses upon re-exposure. The strategy is relevant and useful for increasing the efficiency of vaccinations.