Abstract: Compounds of the formula ##STR1## wherein R.sup.1 is an N-alkanoyl amino acyl group of the formula ##STR2## wherein: W is a divalent aminoacyl radical of the formula:a) ##STR3## wherein A is C.sub.1 -C.sub.10 alkylene or C.sub.5 -C.sub.6 cycloalkylene;(b) ##STR4## wherein R.sup.3 is hydroxymethyl, hydroxyethyl, mercaptomethyl, mercaptoethyl, methylthioethyl, 2-thienyl, 3-indolemethyl, phenyl, benzyl, or substituted phenyl or substituted benzyl in which the benzene ring thereof is substituted with chloro, bromo, iodo, nitro, C.sub.1 -C.sub.3 alkyl, hydroxy, C.sub.1 -C.sub.3 alkylthio, carbamyl, or C.sub.1 -C.sub.3 alkylcarbamyl;(c) ##STR5## wherein X is hydrogen, chloro, bromo, iodo, nitro C.sub.1 -C.sub.3 alkyl, hydroxy, C.sub.1 -C.sub.3 alkoxy, mercapto, C.sub.1 -C.sub.3 alkylthio, carbamyl, or C.sub.1 -C.sub.3 alkylcarbamyl;(d) ##STR6## wherein X.sup.1 is chloro, bromo, or iodo; (e) ##STR7## (f) ##STR8## wherein B is a divalent radical of the formula: --(CH.sub.2).sub.

Abstract: Compounds of the formula ##STR1## wherein R.sup.1 is a group of the formula: ##STR2## wherein A is divalent oxygen, sulfur, sulfinyl, or sulfonyl; A.sup.1 is divalent oxygen, sulfur, sulfinyl, sulfonyl or --NH--; X is hydrogen, chloro, bromo, iodo, nitro, C.sub.1 -C.sub.3 alkyl, hydroxy, C.sub.1 -C.sub.3 alkoxy, mercapto, C.sub.1 -C.sub.3 alkylthio, carbamyl or C.sub.1 -C.sub.3 alkylcarbamyl; X.sup.1 is chloro, bromo or iodo; R.sup.2 is hydrogen, C.sub.1 -C.sub.18 alkyl or C.sub.2 -C.sub.18 alkenyl; W is C.sub.1 -C.sub.10 alkylene or C.sub.2 -C.sub.10 alkenylene; m, n and p are 0 or 1, but if m=0, n must=0; provided: that the sum of the carbon atoms in the R.sup.2 and W groups must be greater than 4 but cannot exceed 21; that when X is mercapto, A and A.sup.1 cannot be sulfinyl or sulfonyl; and that when A and A.sup.1 are sulfinyl or sulfonyl, they must be in equal oxidation states.

Abstract: Iodo-A-23187 derivatives, prepared by reaction of antibiotic A-23187 with iodine monochloride, and salts thereof, which are (1) useful biochemical tools for the study of transport of ions in cellular systems and (2) useful chemical tools for removal of recovery of ions.

Abstract: Halo-A-23187 derivatives, prepared by reaction of antibiotic A-23187 with an N-halo-type halogenating agent, and salts thereof, which are (1) useful biochemical tools for the study of transport of ions in cellular systems, (2) useful chemical tools for removal and recovery of ions, and (3) potential cardiotonic agents.

Abstract: Bromo-A-23187 derivatives, prepared by reaction of antibiotic A-23187 with pyridinium hydrobromide perbromide and salts thereof, which are (1) useful biochemical tools for the study of transport of ions in cellular systems, and (2) useful chemical tools for removal and recovery of ions.

Abstract: Antibiotic A-35512B aglycone, prepared from A-35512 factor B by acid hydrolysis, is a useful antibacterial agent.