Abstract: The present invention concerns methods, in particular in vitro methods, for diagnosing liver fibrosis in a subject suffering from obesity, or for selecting a subject suffering from obesity for liver biopsy or for treatment. The present invention also pertains to methods for screening a probiotic, a prebiotic, a chemical compound or a biological compound suitable for preventing and/or treating liver fibrosis.

Abstract: A positioning device with tolerance compensation including: a screw; a primary tightening member, and a secondary nut. The screw includes a driving portion cooperating with a driving tool to rotatably drive the screw and is located in an axial end portion of the screw; primary and secondary external threads, the primary external thread being further from the driving portion than the secondary external thread, the directions of the secondary external thread and the primary external thread are opposing; and an abutment projecting between the primary and secondary external threads. The primary tightening member includes a primary internal thread adapted to cooperate with the primary external thread, the primary tightening member and the abutment secured to an intermediate component. The secondary nut includes a secondary internal thread cooperating with the secondary external thread and is configured to bear against the intermediate component to fasten a first component on a second component.

Abstract: The present invention concerns methods for diagnosing liver fibrosis in an obese subject, said method comprising the steps of a) determining bacterial diversity in a biological sample from the subject, and b) based on the result of the bacterial diversity determination in step a), diagnosing liver fibrosis in the subject, or comprising the steps of a1) determining the proportion of bacteria belonging to a particular taxon and the proportion of bacteria belonging to at least one other particular taxon, in a biological sample of said subject, a2) combining the proportions determined in step a1) to obtain a combination value, and b) based on the combination value obtained in step a2), diagnosing liver fibrosis in the subject.

Abstract: Compound for treatment of myotonic dystrophy type The present invention relates to a compound, or a salt thereof, and a pharmaceutical composition comprising said compound, or a salt thereof, for use in the prevention and/or treatment of myotonic dystrophy type 1 in a patient, in particular by reducing the levels of autophagy and apoptosis that are elevated in myotonic muscular dystrophy type 1.

Abstract: The present invention relates to the a bismuth-based composition, particularly involving the use of bismuth ions, particularly the Bi+3 ion, for prevention and/or treatment of the haemolytic uremic syndrome, with the invention also relating to the use of a bismuth ion in the manufacture of a medicament for the prevention and/or treatment of an infection caused by a Shiga-toxin producing Escherichia coli strain, as well as to a method for preventing and/or treating the haemolytic uremic syndrome comprising administering bismuth ions to a patient in need thereof, and a method for inhibiting dissemination of the gene encoding virulence factors of a Shiga-toxin producing Escherichia coli strain in animals and humans.

Abstract: A method and a node for storing subscription-related information and a method carried out in a node including a call session control function or applications server function and a corresponding node. There is a need to diminish signaling load in an IMS and/or shorten signaling time, particularly when updating user profiles in respect to service profiles. This is addressed by a method including the steps of receiving a request message identifying a user; determining whether the received request message comprises an indication of support of a user type associated with the user, the user type indicating that the user shares a certain user profile with other users; and storing for the user an attribute associated with the user type, which attribute is common for a plurality of users all associated with the same user type, if the received request message comprises the indication of support of the user type.

Abstract: There is provided a method of processing an IMS session originated by a UE after restart of a S-CSCF that was previously assigned to a user of the UE during registration with the IMS, when a further S-CSCF is currently assigned to the user. The method comprises, at a HSS, receiving a request to register a user identity of the user from the previously assigned S-CSCF, determining that the previously assigned S-CSCF is not the same as a S-CSCF currently assigned to the user, determining if IMS restoration procedures are supported for the UE, and, if IMS restoration procedures are not supported for the UE, sending a response to the previously assigned S-CSCF, the response identifying the further S-CSCF currently assigned to the user.

Abstract: A positioning device with tolerance compensation including: a screw; a primary tightening member, and a secondary nut. The screw includes a driving portion cooperating with a driving tool to rotatably drive the screw and is located in an axial end portion of the screw; primary and secondary external threads, the primary external thread being further from the driving portion than the secondary external thread, the directions of the secondary external thread and the primary external thread are opposing; and an abutment projecting between the primary and secondary external threads. The primary tightening member includes a primary internal thread adapted to cooperate with the primary external thread, the primary tightening member and the abutment secured to an intermediate component. The secondary nut includes a secondary internal thread cooperating with the secondary external thread and is configured to bear against the intermediate component to fasten a first component on a second component.

Abstract: The present invention concerns methods, in particular in vitro methods, for diagnosing liver fibrosis in a subject suffering from obesity, or for selecting a subject suffering from obesity for liver biopsy or for treatment. The present invention also pertains to methods for screening a probiotic, a prebiotic, a chemical compound or a biological compound suitable for preventing and/or treating liver fibrosis.

Abstract: The present invention relates to the a bismuth-based composition, particularly involving the use of bismuth ions, particularly the Bi+3 ion, for prevention and/or treatment of the haemolytic uremic syndrome, with the invention also relating to the use of a bismuth ion in the manufacture of a medicament for the prevention and/or treatment of an infection caused by a Shiga-toxin producing Escherichia coli strain, as well as to a method for preventing and/or treating the haemolytic uremic syndrome comprising administering bismuth ions to a patient in need thereof, and a method for inhibiting dissemination of the gene encoding virulence factors of a Shiga-toxin producing Escherichia coli strain in animals and humans.

Abstract: The present invention relates to the a bismuth-based composition, particularly involving the use of bismuth ions, particularly the Bi+3 ion, for prevention and/or treatment of the haemolytic uremic syndrome, with the invention also relating to the use of a bismuth ion in the manufacture of a medicament for the prevention and/or treatment of an infection caused by a Shiga-toxin producing Escherichia coli strain, as well as to a method for preventing and/or treating the haemolytic uremic syndrome comprising administering bismuth ions to a patient in need thereof, and a method for inhibiting dissemination of the gene encoding virulence factors of a Shiga-toxin producing Escherichia coli strain in animals and humans.

Abstract: A subscriber server routes a terminating call in a network that includes a circuit switched (CS) network, a packet switched (PS) network, and an IP Multimedia Subsystem (IMS). The server receives a request for routing information in relation to the terminating call from a CS node in the CS network. A determination is made at server based on whether a UE associated with the terminating call is registered in the IMS and the UE has access to the PS network. The server instructs the CS node to route the terminating call in the CS network when the UE is not registered in the IMS or when the UE does not have access to the PS network. The server instructs the CS node to send the terminating call to the IMS for handling when the UE is registered in the IMS and when the UE has access to the PS network.

Abstract: A system and method for protecting an instrument panel circuit from overcurrents includes a differential amplifier that magnifies a voltage drop across at least one power input component. The magnified voltage drop is provided to a hysteresis comparator that compares the voltage drop against a pair of hysteresis thresholds. When the voltage drop exceeds the thresholds, an overcurrent is detected and a default state of a power switching element is changed from closed to open.

Abstract: The present application provides a turbine rotor and blade assembly for a steam turbine. The turbine rotor and blade assembly may include a rotor, a number of buckets positioned about the rotor, and a locking blade positioned about the rotor. The locking blade may include a multi-piece configuration.

Abstract: A striking watch including a watch case delimiting an internal chamber, as well as the insert partition defining an acoustic sound emission membrane, the insert partition divides the internal chamber into an acoustic cavity and a tight housing which receives a timepiece movement and a gong provided to vibrate after having received an impact from a striking mechanism associated with the timepiece movement, and the acoustic cavity is delimited at least by the insert partition and by a back cover, and the insert partition bears the gong.

Abstract: A striking watch including a watch case delimiting an internal chamber, as well as the insert partition defining an acoustic sound emission membrane, the insert partition divides the internal chamber into an acoustic cavity and a tight housing which receives a timepiece movement and a gong provided to vibrate after having received an impact from a striking mechanism associated with the timepiece movement, and the acoustic cavity is delimited at least by the insert partition and by a back cover, and the insert partition bears the gong.

Abstract: According to a first aspect there is provided a method of processing an IP Multimedia Subsystem (IMS) session originated by a User Equipment (UE) after failure of a Serving Call Session Control Function (S-CSCF) that was previously assigned to a user of the UE during registration with the IMS. The method comprises, at a Proxy Call Session Control Function (P-CSCF), upon determining that the P-CSCF is unable to forward a session establishment request for the session to the previously assigned S-CSCF, selecting an alternative S-CSCF from a S-CSCF pool, and sending the session establishment request for the session to the alternative S-CSCF.

Abstract: There is provided a method of processing an IMS session originated by a UE after restart of a S-CSCF that was previously assigned to a user of the UE during registration with the IMS, when a further S-CSCF is currently assigned to the user. The method comprises, at a HSS, receiving a request to register a user identity of the user from the previously assigned S-CSCF, determining that the previously assigned S-CSCF is not the same as a S-CSCF currently assigned to the user, determining if IMS restoration procedures are supported for the UE, and, if IMS restoration procedures are not supported for the UE, sending a response to the previously assigned S-CSCF, the response identifying the further S-CSCF currently assigned to the user.

Abstract: A transport container includes a container body (14) and a container lid (12) pivotably mounted at the container body, with a multitude of guide rollers (58) at the container body (14) and a telescopic handle (64) spaced apart from the guide rollers (58), each at the side of the container body (14) opposite the container lid (12). A stacking frame (50) is attached to the rectangular container body (14), or is integrated into the rectangular container body (14). The container body (14) has rounded corners, but is free of supports or recesses (82) for guide rollers (58). The stacking frame (50) forms at least three stacking guides (52, 54), and the guide rollers (58) are mounted inside or at the stacking frame (50).

Abstract: The present invention faces the issue of UE enabled to communicate with an IP Multimedia Subsystem following protocol versions older than Release 9, and provides for an alternative P-CSCF restoration procedure.