Abstract: Methods of generating websites using any combination of remotely and locally stored content are contemplated. Content is procured by a user on a client computer, and a request to add that content to a source folder is sent to a server. The server adds the content to the source folder, where it is made available for website creation. When a client requests creation of a website using the contents of a source folder, the server then generates that website. In some embodiments, the website can be generated according to a user-selected theme or a default theme.

Abstract: A method for referencing an image comprises the steps of displaying the image on a first display device, receiving selection of at least a portion of the image via the first display device, receiving content, wherein the content is associated with and digitally linked to at least the portion of the image for which selection was received, transmitting the image as part of a message included in a continuous stream of messages from the first display device to a second display device, displaying at least a portion of the message on the second display device as part of the continuous stream of messages, and displaying the content on the second display device and indicating that the content is associated with the specific portion of the image.

Abstract: The present invention provides compositions comprising methylnaltrexone or a salt thereof, and compositions and formulations thereof, for oral administration.

Abstract: A method for referencing a message comprises the steps of receiving selection of an area or object associated with the message on a display, optionally providing an indication that the selection of the area or object has been received, allowing a further message to be formed with a link to the message, wherein the link is associated with the further message responsive to the selection, and causing display of the information associated with the message responsive to selection of a further area or portion.

Abstract: Embodiments of the present invention include methods and systems for sharing content in a group slideshow. A plurality of devices, including at least one host device and one or more participant devices, executes a client application by which users can save and organize a plurality of content items on a server storage system. The host can select two or more content items for inclusion in a group slideshow session. With each selection, the server automatically transmits participant copies of the content items to participants, and the participants' client applications automatically display the content items. The participants can view and interact with (e.g., zoom in, save, edit) their respective copies of the content items. When the host adds more content items to the group slideshow session, the participants can catch up to see the content item that the host is currently viewing.

Abstract: Methods of generating websites using any combination of remotely and locally stored content are contemplated. Content is procured by a user on a client computer, and a request to add that content to a source folder is sent to a server. The server adds the content to the source folder, where it is made available for website creation. When a client requests creation of a website using the contents of a source folder, the server then generates that website. In some embodiments, the website can be generated according to a user-selected theme or a default theme.

Abstract: A method of managing message communication improves computer security, the method comprising the steps of: first selecting or creating a first group wave rule that identifies a subset of a plurality of message actors; first providing the subset of the plurality of message actors with access to a message sidebar, wherein the plurality of message actors communicate with each other in a message channel associated with the sidebar, and an excluded actor of the plurality of message actors is excluded from access to the sidebar; second selecting or creating a second group wave rule that relates to the excluded actor; receiving one or more responsive messages in the sidebar from the subset responsive to the first providing; and second providing the excluded actor with access to the sidebar.

Abstract: A health care provider (HCP) engagement engine is disclosed. The HCP engagement engine facilitates effective communication between pharmaceutical sales representatives (pharma reps) and HCPs by tracking actions performed by pharma reps to sell products to HCPs, analyzing the actions, and eliminating confounding effects due to inbound and outbound activities. Inbound activities include behaviors performed by pharma reps to the HCPs, while outbound activities are taken by HCPs in response to the inbound activities. Reducing confounding allows the pharma reps to have better information about which behaviors best drive HCP engagement.

Abstract: The present invention provides compositions comprising methylnaltrexone or a salt thereof, and compositions and formulations thereof, for oral administration.

Abstract: A computer-implemented content suggestion engine provides content suggestions to a requesting user based on information about content items that other users may have independently categorized or organized into folders within a content repository. Embodiments of the method comprise a content repository having a plurality of content items, where each content item is associated with one or more user-created folders. Embodiments further comprise receiving, via a network, a suggestion request for suggested content, where the suggestion request identifies a first content item for which suggestions are sought. Other content items in the content repository are then identified as potential suggestions based on the application of a formal relationship between the first content item and the potential suggested content items. One or more of the potential suggested content items may then be provided in response to the suggestion request via the network.

Abstract: The present invention provides compositions comprising methylnaltrexone or a salt thereof, and compositions and formulations thereof, for oral administration.

Abstract: When a user conducts a search for content using one or more of the many search engines known in the art, embodiments of the present invention may receive results returned to the user's browser by the search engine, and may then proceed to filter, organize, modify, or enhance those results and/or their presentation by performing various editing and/or presentation operations on the search results, based on information relating to the user's prior interactions with the search results and the user's interests and preferences. Search results may also be modulated based on information about the way other users have responded to or interacted with each of the search results in the past.

Abstract: The embodiments of the present invention provide a novel way of searching and interacting with content available via a network, such as the Internet, and the World Wide Web. In some embodiments, systems and methods provide a semantically-oriented structure for organizing and accessing content items. The semantic organization can be derived by leveraging user interactions with the content items. The systems and methods leverage the semantics of the content items and to help the user find content items that are consistent with the purpose of the user's search. In addition, the embodiments provide a novel navigation paradigm of search results and content items so that the user can more intuitively and more efficiently get information form an information space.

Abstract: A method of displaying messages on a display device comprises the steps of: a) displaying on the display device a first plurality of messages including a first new message exchanged in a first messaging channel while at least partially preventing display of a second plurality of messages exchanged in a second messaging channel; b) detecting receipt of a second new message of the second plurality of messages without displaying the second plurality of messages in the second messaging channel; c) providing a physical indication of the detecting; d) enabling interaction with the display device; and e) displaying the second message in said second channel responsive to said interaction.

Abstract: A computer-implemented content suggestion engine provides content suggestions to a requesting user based on information about content items that other users may have independently categorized or organized into folders within a content repository. Embodiments of the method comprise a content repository having a plurality of content items, where each content item is associated with one or more user-created folders. Embodiments further comprise receiving, via a network, a suggestion request for suggested content, where the suggestion request identifies a first content item for which suggestions are sought. Other content items in the content repository are then identified as potential suggestions based on the application of a formal relationship between the first content item and the potential suggested content items. One or more of the potential suggested content items may then be provided in response to the suggestion request via the network.

Abstract: The present invention provides compositions comprising methylnaltrexone or a salt thereof, and compositions and formulations thereof, for oral administration.

Abstract: A method of managing message communication improves computer security, the method comprising the steps of: first selecting or creating a first group wave rule that identifies a subset of a plurality of message actors; first providing the subset of the plurality of message actors with access to a message sidebar, wherein the plurality of message actors communicate with each other in a message channel associated with the sidebar, and an excluded actor of the plurality of message actors is excluded from access to the sidebar; second selecting or creating a second group wave rule that relates to the excluded actor; receiving one or more responsive messages in the sidebar from the subset responsive to the first providing; and second providing the excluded actor with access to the sidebar.

Abstract: The disclosure features, inter alia, combination therapies comprising durvalumab and one or more immunogenic XBP1-, CD138-, and CS1-derived peptides. The therapies herein can be used, e.g., for inducing an immune response in a subject having a solid tumor, and treating a solid tumor, e.g., breast cancer, e.g., triple negative breast cancer.

Abstract: When a user conducts a search for content using one or more of the many search engines known in the art, embodiments of the present invention may receive results returned to the user's browser by the search engine, and may then proceed to filter, organize, modify, or enhance those results and/or their presentation by performing various editing and/or presentation operations on the search results, based on information relating to the user's prior interactions with the search results and the user's interests and preferences. Search results may also be modulated based on information about the way other users have responded to or interacted with each of the search results in the past.

Abstract: The present invention provides compositions comprising methylnaltrexone or a salt thereof, and compositions and formulations thereof, for oral administration.