Patents by Inventor Marc Fine

Marc Fine has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190333955
    Abstract: Among other things, an integral image sensor includes a sensor surface having a surface area at which light-sensitive pixels are arranged in rows and columns. The surface area includes two or more light-sensitive subareas each of the subareas having been configured to have been diced from a wafer along two orthogonal dimensions to form a discrete image sensor. The two or more light-sensitive subareas are arranged along one of the two orthogonal dimensions. The sensor surface of the integral image sensor is flat and continuous across the two or more subareas.
    Type: Application
    Filed: February 22, 2019
    Publication date: October 31, 2019
    Inventors: Alan Marc Fine, Madhuranga Srinath Rankaduwa
  • Patent number: 10461112
    Abstract: Among other things, an integral image sensor includes a sensor surface having a surface area at which light-sensitive pixels are arranged in rows and columns. The surface area includes two or more light-sensitive subareas each of the subareas having been configured to have been diced from a wafer along two orthogonal dimensions to form a discrete image sensor. The two or more light-sensitive subareas are arranged along one of the two orthogonal dimensions. The sensor surface of the integral image sensor is flat and continuous across the two or more subareas.
    Type: Grant
    Filed: February 22, 2019
    Date of Patent: October 29, 2019
    Assignee: Alentic Microscience Inc.
    Inventors: Alan Marc Fine, Madhuranga Srinath Rankaduwa
  • Patent number: 10459213
    Abstract: Among other things, a first surface is configured to receive a sample and is to be used in a microscopy device. There is a second surface to be moved into a predefined position relative to the first surface to form a sample space that is between the first surface and the second surface and contains at least part of the sample. There is a mechanism configured to move the second surface from an initial position into the predefined position to form the sample space. When the sample is in place on the first surface, the motion of the second surface includes a trajectory that is not solely a linear motion of the second surface towards the first surface.
    Type: Grant
    Filed: June 1, 2018
    Date of Patent: October 29, 2019
    Assignee: Alentic Microscience Inc.
    Inventors: Alan Marc Fine, Hershel Macaulay, Noah Hymes-Vandermeulen
  • Publication number: 20190324258
    Abstract: Among other things, a first surface is configured to receive a sample and is to be used in a microscopy device. There is a second surface to be moved into a predefined position relative to the first surface to form a sample space that is between the first surface and the second surface and contains at least part of the sample. There is a mechanism configured to move the second surface from an initial position into the predefined position to form the sample space. When the sample is in place on the first surface, the motion of the second surface includes a trajectory that is not solely a linear motion of the second surface towards the first surface.
    Type: Application
    Filed: June 27, 2019
    Publication date: October 24, 2019
    Inventors: Alan Marc Fine, Hershel Macaulay, Noah Hymes-Vandermeulen
  • Publication number: 20190324239
    Abstract: Among other things, an imaging device has a photosensitive array of pixels, and a surface associated with the array is configured to receive a specimen with at least a part of the specimen at a distance from the surface equivalent to less than about half of an average width of the pixels.
    Type: Application
    Filed: June 12, 2019
    Publication date: October 24, 2019
    Applicant: Alentic Microscience Inc.
    Inventors: Alan Marc Fine, Peter Hodges Gregson
  • Publication number: 20190317309
    Abstract: Among other things, a first surface is configured to receive a sample and is to be used in a microscopy device. There is a second surface to be moved into a predefined position relative to the first surface to form a sample space that is between the first surface and the second surface and contains at least part of the sample. There is a mechanism configured to move the second surface from an initial position into the predefined position to form the sample space. When the sample is in place on the first surface, the motion of the second surface includes a trajectory that is not solely a linear motion of the second surface towards the first surface.
    Type: Application
    Filed: June 27, 2019
    Publication date: October 17, 2019
    Inventors: Alan Marc Fine, Hershel Macaulay, Noah Hymes-Vandermeulen
  • Publication number: 20190293524
    Abstract: Among other things, a diluted sample is generated based on mixing a small sample of blood with a one or more diluents. A thin film of the diluted sample is formed on the surface of a contact optical microscopy sensor. Red blood cells within a portion of the thin film of the diluted sample are illuminated using light of a predetermined wavelength. One or more images of the diluted sample are acquired based on illuminating the red blood cells within the portion of the thin film of the diluted sample. The acquired one or more images of the diluted sample are then processed. The mean corpuscular hemoglobin in the red blood cells within the portion of the thin film of the diluted sample is determined based on processing the acquired images of the diluted sample.
    Type: Application
    Filed: March 10, 2016
    Publication date: September 26, 2019
    Inventors: Alan Marc Fine, Hershel Macaulay
  • Publication number: 20190278075
    Abstract: In some instances, an apparatus can include a light sensitive imaging sensor having a surface to receive a fluid sample, a body to be moved relative to the light sensitive imaging sensor and having a surface to touch a portion of the fluid sample, and a carrier to move the body toward the surface of the light sensitive imaging sensor to cause the surface of the body to touch the portion of the fluid sample, so that as the surface of the body touches the portion of the fluid, the surface of the body (i) is parallel to the surface of the light sensitive imaging sensor, and (ii) settles on top of the fluid sample independently of motion of the carrier.
    Type: Application
    Filed: May 6, 2019
    Publication date: September 12, 2019
    Inventor: Alan Marc Fine
  • Publication number: 20190242794
    Abstract: Among other things, a diluted sample is generated based on mixing a small sample of blood with a one or more diluents. A thin film of the diluted sample is formed on the surface of a contact optical microscopy sensor. Red blood cells within a portion of the thin film of the diluted sample are illuminated using light of a predetermined wavelength. One or more images of the diluted sample are acquired based on illuminating the red blood cells within the portion of the thin film of the diluted sample. The acquired one or more images of the diluted sample are then processed. The mean corpuscular hemoglobin in the red blood cells within the portion of the thin film of the diluted sample is determined based on processing the acquired images of the diluted sample.
    Type: Application
    Filed: March 28, 2019
    Publication date: August 8, 2019
    Inventors: Alan Marc Fine, Hershel Macaulay
  • Patent number: 10345564
    Abstract: Among other things, an imaging device has a photosensitive array of pixels, and a surface associated with the array is configured to receive a specimen with at least a part of the specimen at a distance from the surface equivalent to less than about half of an average width of the pixels.
    Type: Grant
    Filed: August 27, 2018
    Date of Patent: July 9, 2019
    Assignee: Alentic Microscience Inc.
    Inventors: Alan Marc Fine, Peter Hodges Gregson
  • Patent number: 10317662
    Abstract: In some instances, an apparatus can include a light sensitive imaging sensor having a surface to receive a fluid sample, a body to be moved relative to the light sensitive imaging sensor and having a surface to touch a portion of the fluid sample, and a carrier to move the body toward the surface of the light sensitive imaging sensor to cause the surface of the body to touch the portion of the fluid sample, so that as the surface of the body touches the portion of the fluid, the surface of the body (i) is parallel to the surface of the light sensitive imaging sensor, and (ii) settles on top of the fluid sample independently of motion of the carrier.
    Type: Grant
    Filed: April 7, 2017
    Date of Patent: June 11, 2019
    Assignee: Alentic Microscience Inc.
    Inventor: Alan Marc Fine
  • Publication number: 20190162648
    Abstract: Among other things, an imaging sensor includes a two-dimensional array of photosensitive elements and a surface to receive a sample within a near-field distance of the photosensitive elements. Electronics classify microbeads in the sample as belonging to different classes based on the effects of different absorption spectra of the different classes of microbeads on light received at the surface. In some examples, the number of different distinguishable classes of microbeads can be very large based on combinations of the effects on light received at the surface of the different absorption spectra together, spatial arrangements of colorants in the microbeads that impart the different absorption spectra, different sizes of microbeads, and different shapes of microbeads, among other things.
    Type: Application
    Filed: November 20, 2018
    Publication date: May 30, 2019
    Inventor: Alan Marc Fine
  • Patent number: 10249669
    Abstract: Among other things, an integral image sensor includes a sensor surface having a surface area at which light-sensitive pixels are arranged in rows and columns. The surface area includes two or more light-sensitive subareas each of the subareas having been configured to have been diced from a wafer along two orthogonal dimensions to form a discrete image sensor. The two or more light-sensitive subareas are arranged along one of the two orthogonal dimensions. The sensor surface of the integral image sensor is flat and continuous across the two or more subareas.
    Type: Grant
    Filed: December 5, 2018
    Date of Patent: April 2, 2019
    Assignee: Alentic Microscience Inc.
    Inventors: Alan Marc Fine, Madhuranga Srinath Rankaduwa
  • Publication number: 20190094509
    Abstract: Among other things, an imaging device has a photosensitive array of pixels, and a surface associated with the array is configured to receive a specimen with at least a part of the specimen at a distance from the surface equivalent to less than about half of an average width of the pixels.
    Type: Application
    Filed: August 27, 2018
    Publication date: March 28, 2019
    Applicant: Alentic Microscience Inc.
    Inventors: Alan Marc Fine, Peter Hodges Gregson
  • Publication number: 20190094510
    Abstract: Among other things, a method comprises imaging a sample displaced between a sensor surface and a surface of a microscopy sample chamber to produce an image of at least a part of the sample. The image is produced using lensless optical microscopy, and the sample contains at least blood from a subject. The method also comprises automatically differentiating cells of different types in the image, generating a count of one or more cell types based on the automatic differentiation, and deriving a radiation dose the subject has absorbed based on the count.
    Type: Application
    Filed: October 11, 2018
    Publication date: March 28, 2019
    Applicant: Alentic Microscience Inc.
    Inventor: Alan Marc Fine
  • Patent number: 10153317
    Abstract: Among other things, an integral image sensor includes a sensor surface having a surface area at which light-sensitive pixels are arranged in rows and columns. The surface area includes two or more light-sensitive subareas each of the subareas having been configured to have been diced from a wafer along two orthogonal dimensions to form a discrete image sensor. The two or more light-sensitive subareas are arranged along one of the two orthogonal dimensions. The sensor surface of the integral image sensor is flat and continuous across the two or more subareas.
    Type: Grant
    Filed: April 26, 2018
    Date of Patent: December 11, 2018
    Assignee: Alentic Microscience Inc.
    Inventors: Alan Marc Fine, Madhuranga Srinath Rankaduwa
  • Patent number: 10114203
    Abstract: Among other things, an imaging device has a photosensitive array of pixels, and a surface associated with the array is configured to receive a specimen with at least a part of the specimen at a distance from the surface equivalent to less than about half of an average width of the pixels.
    Type: Grant
    Filed: July 6, 2017
    Date of Patent: October 30, 2018
    Assignee: Alentic Microscience Inc.
    Inventors: Alan Marc Fine, Peter Hodges Gregson
  • Patent number: 10107997
    Abstract: Among other things, a method comprises imaging a sample displaced between a sensor surface and a surface of a microscopy sample chamber to produce an image of at least a part of the sample. The image is produced using lensless optical microscopy, and the sample contains at least blood from a subject. The method also comprises automatically differentiating cells of different types in the image, generating a count of one or more cell types based on the automatic differentiation, and deriving a radiation dose the subject has absorbed based on the count.
    Type: Grant
    Filed: April 2, 2018
    Date of Patent: October 23, 2018
    Assignee: Alentic Microscience Inc.
    Inventor: Alan Marc Fine
  • Publication number: 20180284416
    Abstract: Among other things, a first surface is configured to receive a sample and is to be used in a microscopy device. There is a second surface to be moved into a predefined position relative to the first surface to form a sample space that is between the first surface and the second surface and contains at least part of the sample. There is a mechanism configured to move the second surface from an initial position into the predefined position to form the sample space. When the sample is in place on the first surface, the motion of the second surface includes a trajectory that is not solely a linear motion of the second surface towards the first surface.
    Type: Application
    Filed: June 1, 2018
    Publication date: October 4, 2018
    Inventors: Alan Marc Fine, Hershel Macaulay, Noah Hymes-Vandermeulen
  • Publication number: 20180231753
    Abstract: Among other things, a method comprises imaging a sample displaced between a sensor surface and a surface of a microscopy sample chamber to produce an image of at least a part of the sample. The image is produced using lensless optical microscopy, and the sample contains at least blood from a subject. The method also comprises automatically differentiating cells of different types in the image, generating a count of one or more cell types based on the automatic differentiation, and deriving a radiation dose the subject has absorbed based on the count.
    Type: Application
    Filed: April 2, 2018
    Publication date: August 16, 2018
    Applicant: Alentic Microscience Inc.
    Inventor: Alan Marc Fine