Abstract: The instant invention provides compounds of Formula Ia which are leukotriene biosynthesis inhibitors. Compounds of Formula Ia are useful as anti-atherosclerotic, anti-asthmatic, anti-allergic, anti-inflammatory and cytoprotective agents.

Abstract: Heteroaromatic compounds of structural formula (I) are selective inhibitors of stearoyl-coenzyme A delta-9 desaturase (SCD1) relative to other known stearoyl-coenzyme A desaturases. The compounds of the present invention are useful for the prevention and treatment of conditions related to abnormal lipid synthesis and metabolism, including cardiovascular disease; atherosclerosis; lipid disorders; obesity; diabetes; neurological disease; metabolic syndrome; insulin resistance; and fatty liver disease.

Abstract: The invention encompasses novel compounds of Formula I or pharmaceutically acceptable salts thereof. These compounds are inhibitors of the microsomal prostaglandin E synthase-1 (mPGES-1) enzyme and are therefore useful to treat pain and/or inflammation from a variety of diseases or conditions, such as osteoarthritis, rheumatoid arthritis and acute or chronic pain. Methods of treating diseases or conditions mediated by the mPGES-1 enzyme and pharmaceutical compositions are also encompassed.

Abstract: The instant invention provides compounds of Formula Ia which are leukotriene biosynthesis inhibitors. Compounds of Formula Ia are useful as anti-atherosclerotic, anti-asthmatic, anti-allergic, anti-inflammatory and cytoprotective agents.

Abstract: The invention encompasses novel compounds of Formula I or pharmaceutically acceptable salts thereof. These compounds are inhibitors of the microsomal prostaglandin E synthase-1 (mPGES-1) enzyme and are therefore useful to treat pain and/or inflammation from a variety of diseases or conditions, such as osteoarthritis, rheumatoid arthritis and acute or chronic pain. Methods of treating diseases or conditions mediated by the mPGES-1 enzyme and pharmaceutical compositions are also encompassed.

Abstract: The instant invention provides compounds of Formula I which are leukotriene biosynthesis inhibitors. Compounds of Formula I are useful as anti-atherosclerotic, anti-asthmatic, anti-allergic, anti-inflammatory and cytoprotective agents.

Abstract: A vehicle has a vehicle body, a seat, an engine, an ECU, a throttle body, a throttle valve, a throttle valve actuator, a throttle operator, and a throttle operator position sensor. A shifter is disposed on the vehicle in proximity to the seat for selecting a vehicle operation direction between a forward direction and a reverse direction. A vehicle operation direction sensor senses the vehicle operation direction. The ECU limits a maximum speed of the vehicle when it operates in the reverse direction. In another aspect, the ECU limits the degree of opening of the throttle valve when it operates in the reverse direction. Methods of controlling an engine are also disclosed.

Abstract: A vehicle has a straddle seat, a handlebar, an engine, an electronic control unit (ECU), a throttle valve, a throttle valve actuator, and a throttle operator. A throttle operator position sensor senses a throttle operator position. A vehicle speed sensor senses a vehicle speed. The ECU sends a control signal to the throttle valve actuator based on the throttle operator position and the vehicle speed. The throttle valve actuator adjusts the opening of the throttle valve in response to the control signal. If the vehicle speed is lower than a predetermined maximum vehicle speed, the throttle valve actuator adjusts the opening of the throttle valve based on the throttle operator position signal. If the vehicle speed is higher than the predetermined maximum vehicle speed, the throttle valve actuator reduces the degree of opening of the throttle valve. A method of controlling an engine is also disclosed.

Abstract: This invention relates to class of compounds which are cysteine protease inhibitors, including but not limited to, inhibitors of cathepsins K, L, S and B. These compounds are useful for treating diseases in which inhibition of bone resorption is indicated, such as osteoporosis.

Abstract: The invention encompasses novel compounds of Formula I or pharmaceutically acceptable salts thereof. These compounds are inhibitors of the microsomal prostaglandin E synthase-1 (mPGES-1) enzyme and are therefore useful to treat pain and/or inflammation from a variety of diseases or conditions, such as osteoarthritis, rheumatoid arthritis and acute or chronic pain. Methods of treating diseases or conditions mediated by the mPGES-1 enzyme and pharmaceutical compositions are also encompassed.

Abstract: The instant invention provides compounds of Formula Ia which are leukotriene biosynthesis inhibitors. Compounds of Formula Ia are useful as anti-atherosclerotic, anti-asthmatic, anti-allergic, anti-inflammatory and cytoprotective agents.

Abstract: A communications system in which a plurality of transmitter and receiver stations, wherein the transmitter stations are co-located in the same geographic area and capable of communication with each other and an improved method of Automatic Transmitter Power Control (ATPC) operation, wherein the method allows only one transmitter to engage in ATPC at a time per channel set and another improved method of ATPC in which there exists at least two co-located transmitters capable of ATPC operation and wherein the transmitters share transmitter ATPC status.

Abstract: This invention relates to class of compounds which are cysteine protease inhibitors, including but not limited to, inhibitors of cathepsins K, L, S and B. These compounds are useful for treating diseases in which inhibition of bone resorption is indicated, such as osteoporosis. They have the following structure: Formula (I).

Abstract: The invention provides a shirt suitable for being worn by a sports player. The shirt comprises a torso portion having a head opening and a lower trunk opening; and first and second sleeves, each of the first and second sleeves comprising biceps, elbow and forearm portions and a gripping zone provided on one of the biceps, elbow and forearm portions. The gripping zone is made of a material having a coefficient of friction sufficient for preventing movement between said shirt and an elbow pad worn by the sports player.

Abstract: A communications system in which a plurality of transmitter and receiver stations, wherein the transmitter stations are co-located in the same geographic area and capable of communication with each other and an improved method of Automatic Transmitter Power Control (ATPC) operation, wherein the method allows only one transmitter to engage in ATPC at a time per channel set and another improved method of ATPC in which there exists at least two co-located transmitters capable of ATPC operation and wherein the transmitters share transmitter ATPC status.

Abstract: An accurate method for characterizing optical fiber using a modest enhancement to equipment that is already in place for other purposes within an optical transmission system is thereby disclosed. In particular, optical amplifier light sources already embedded in transmission equipment are used to provide accurate characterization information in addition to their conventional purpose. Therefore, the invention permits fiber characterization at little additional cost over the optical amplifier light sources already present in a system. Furthermore, the need of going out to the field, disconnecting the transmission equipment and performing the field measurements with separate test equipment is eliminated.