Patents by Inventor Marc Holtwick

Marc Holtwick has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160317753
    Abstract: Assembly for a drug delivery device and drug delivery device An assembly for a drug delivery device (1) is described comprising an activation member (6A) adapted and arranged to be axially moved in a delivery direction for triggering a dose delivery operation of the assembly, a first interaction member (17) and a second interaction member (18) which are adapted and arranged to mechanically cooperate with one another during a dose delivery operation of the assembly and to be rotated with respect to one another during the dose delivery operation, wherein the assembly is configured such that movement of the activation member (6A) in the delivery direction brings the interaction members (17, 18) into mechanical contact for generating a friction between the interaction members (17, 18), wherein an amount of friction controls a relative rotational speed of the interaction members (17, 18) during a dose delivery operation. Furthermore, a drug delivery device comprising the assembly is described.
    Type: Application
    Filed: December 18, 2014
    Publication date: November 3, 2016
    Inventors: Michael JUGL, Axel TEUCHER, Marc HOLTWICK
  • Publication number: 20160317750
    Abstract: An assembly for a drug delivery device (1) is described comprising at least one drive member (19, 26) adapted and arranged to be moved in a delivery direction during a dose delivery operation of the assembly and in a direction opposite to the delivery direction during a dose setting operation of the assembly, an energy storing member (16) adapted and arranged to store energy and to cause movement of the drive member (19, 26) in the delivery direction, and an interaction system adapted and arranged to generate a friction onto the drive member (19, 26), wherein an amount of friction regulates a speed of movement of the drive member (19, 26) when drive member (19, 26) is moved in the delivery direction. Furthermore, a drug delivery device comprising the assembly is described.
    Type: Application
    Filed: December 18, 2014
    Publication date: November 3, 2016
    Applicant: Sanofi-Aventis Deutschland GMBH
    Inventors: Michael Jugl, Axel Teucher, Marc Holtwick
  • Publication number: 20160317749
    Abstract: An assembly for a drug delivery device (1) is described comprising a piston rod (12) adapted and arranged to be displaceable in a delivery direction for dispensing a dose of a drug (10) from the device (1), an energy storing member (16) which is adapted and arranged to store energy and to move the piston rod (12) in the delivery direction, and an interaction member (7) adapted and arranged to mechanically cooperate with the piston rod (12), wherein the interaction member (7) is displaceable between a first position and a second position with respect to the piston rod (12), wherein the interaction member (7) is configured to be moved from the first position towards the second position to increase a friction onto the piston rod (12) and, wherein the interaction member (7) is configured to be moved from the second position back into the first position to decrease the friction onto the piston rod (12). Furthermore, a drug delivery device (1) comprising the assembly is described.
    Type: Application
    Filed: December 18, 2014
    Publication date: November 3, 2016
    Inventors: Michael Jugl, Axel Teucher, Marc Holtwick
  • Publication number: 20160288974
    Abstract: The invention relates to a blister package (500, 700, 800, 1000, 1100, 1200, 1320, 1420) for packaging a dispense interface (200, 2000) of a medicament ejection device, with a blister (510, 710, 810, 1010, 1110, 1210) having a cavity portion (512, 712, 812, 1012, 1112, 1212) and a flange (514, 1014, 1214), the cavity portion (512, 712, 812, 1012, 1112, 1212) defining a cavity (516) and being configured to hold a dispense interface (200, 2000) of a medicament ejection device within the cavity (516), and with a lid (520, 720, 1020, 1120, 820) bonded to the flange (514, 1014, 1214) of said blister (510, 710, 810, 1010, 1110, 1210), wherein the cavity portion (512, 712, 812, 1012, 1112, 1212) of said blister (510, 710, 810, 1010, 1110, 210) comprises at least one undercut portion configured to interact with a corresponding part of a dispense interface (200, 2000) to be packaged in the blister package (500, 700, 800, 1000, 1100, 1200, 1320, 1420) to lock the dispense interface (200, 2000) within the cavity (516).
    Type: Application
    Filed: November 19, 2014
    Publication date: October 6, 2016
    Inventors: Marc Holtwick, Jens Schnur, Andreas Krämmerer, Gilbert Robel
  • Patent number: 9402965
    Abstract: A medicament delivery device comprises a housing having a longitudinal axis, a medicament delivery mechanism within the housing, a dispense interface disengagement actuator and a detachable dispense interface. The interface is moveable between a first operative position in which the dispense interface is securely engaged and at least partially contained within the housing, and a second non-operative position in which the dispense interface is partially engaged and at least partially extending from the housing such that it can be detached from the housing manually. The travel of the dispense interface from the first position to the second position is along the longitudinal axis in a direction away from the housing and the movement from the first to the second position is actuated by the dispense interface disengagement actuator.
    Type: Grant
    Filed: May 24, 2012
    Date of Patent: August 2, 2016
    Assignee: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Marc Holtwick, Ilona Eggert, Christopher Nigel Langley, Aled Meredydd James
  • Publication number: 20160213849
    Abstract: The invention relates to an apparatus for ejecting a fluid having a control unit (510) for controlling the apparatus, the control unit (510) being configured to control fluid dose ejection steps and to determine a priming time length (Tprime), the priming time length (Tprime) being the length of time since the last ejection of a fluid volume through the ejection channel, wherein the control unit (510) is further configured to perform a priming test step (612-618) comprising the steps of: determining whether the priming time length (Tprime) is longer than a predefined priming threshold time length (Tthreshold); and setting the apparatus into a status, in which a further fluid dose ejection step is only allowed after execution of an ejection channel priming step (622-628) if the priming time length (Tprime) is longer than the priming threshold time length (Tthreshold).
    Type: Application
    Filed: September 18, 2014
    Publication date: July 28, 2016
    Inventor: Marc HOLTWICK
  • Patent number: 9375562
    Abstract: The present invention inter-alia relates to an apparatus comprising a diaphragm valve, wherein a diaphragm of said diaphragm valve is made from a substantially rigid material, having at least partially an flexible cross-sectional shape.
    Type: Grant
    Filed: May 4, 2012
    Date of Patent: June 28, 2016
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventor: Marc Holtwick
  • Publication number: 20160067416
    Abstract: An assembly for a drug delivery device is provided, the assembly having a compression spring, wherein the compression spring is compressed during the setting of a dose of a drug. The assembly further comprises a sleeve member, wherein the compression spring is in direct contact with the sleeve member and wherein the compression spring and the sleeve member are configured such that a relaxation of the compression spring effects a rotational and an axial movement of the sleeve member in a proximal direction, thereby causing a dispensing of a dose from the drug delivery device.
    Type: Application
    Filed: May 13, 2014
    Publication date: March 10, 2016
    Inventors: Marc HOLTWICK, Michael JUGL, Axel TEUCHER
  • Publication number: 20150265771
    Abstract: The present invention is directed at a dose setting mechanism for a drug delivery device, comprising an outer sleeve and an inner sleeve located at least partially within the outer sleeve wherein the outer sleeve is connected to the inner sleeve. To reduce noise excitations of the dose setting mechanism, at least one intermediate element is at least partially located in a clearance between the inner sleeve and the outer sleeve in such way that it reduces the relative movement of the inner sleeve and the outer sleeve along a play between the inner sleeve and the outer sleeve. The invention is further directed to a pen-type injector equipped with a respective dose setting mechanism.
    Type: Application
    Filed: November 5, 2013
    Publication date: September 24, 2015
    Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Marc Holtwick, Michael Jugl, Axel Teucher
  • Publication number: 20150224258
    Abstract: The invention inter alia relates to a dispense interface for an ejection device comprises at least two inlets; at least one outlet; a body portion; and a cover film; wherein the body portion and the cover film are bonded together; wherein the body portion and the cover film are configured to form a fluid channel arrangement between surfaces of the body portion and the cover film facing each other when the body portion and the cover film are bonded together; and wherein the fluid channel arrangement is configured to provide fluid communication between the at least two inlets and the at least one outlet.
    Type: Application
    Filed: August 7, 2013
    Publication date: August 13, 2015
    Inventors: Marc Holtwick, Wolfgang Marx, Frederic Laugere, Cristian Popa, Ben Impey, Andrew McLeod
  • Publication number: 20140364811
    Abstract: The present invention relates to method of manufacturing a fluid guiding assembly for a drug delivery device and to a respective fluid guiding assembly. Said method comprising the steps of: providing a first member having at least one recess in a first surface portion, at least partially filling the recess with a joining component at least partially protruding from the first surface portion of the first member, arranging a second member having a second surface portion adjacent to the first member such that first and second surface portions thereof face towards each other to form an interface area between the first and the second members, wherein the joining component comprises a material different to the material of the first and/or second member wherein at least one channel structure extending along the interface area is formed by at least one deepening of the first member and/or of the second member, selectively providing thermal energy to the joining component to bond together first and second members.
    Type: Application
    Filed: November 15, 2012
    Publication date: December 11, 2014
    Applicant: Sanofi-Aventis Deutschland GmbH
    Inventors: Marc Holtwick, Martin Haupt
  • Publication number: 20140316341
    Abstract: A fluid guiding assembly for a drug delivery device is presented having a first member, a cover part adjacently disposed to the first member and being in non-bonded surface contact with a surface portion of the first member thereby forming an interface area, at least one channel structure extending along the interface area of first member and cover part and being formed by at least one recess in either the first member and/or in the cover part, and a second member being in contact with the cover part and being bonded to the first member by way of injection moulding to fix the cover part relative to the first member.
    Type: Application
    Filed: November 15, 2012
    Publication date: October 23, 2014
    Inventors: Marc Holtwick, Martin Haupt
  • Publication number: 20140200520
    Abstract: The invention faces the technical problem of reducing the manufacturing costs of medical devices while at the same time a secure, quick and easy reception of a needle by said medical device is guaranteed. The technical problem is solved by a needle guide configured to receive a needle in a first opening in an axial direction of the needle guide, comprising a guide area comprising the first opening and a second opening, a flange area and a connection area, wherein said connection area is configured to non-detachably connect said needle guide to a medical device and wherein said needle guide is made of metal. The technical problem is further solved by a method to produce a needle guide, wherein said needle guide comprises a guide area, a flange area and a connection area, comprising the steps of deep drawing a metal sheet to produce the guide area.
    Type: Application
    Filed: May 4, 2012
    Publication date: July 17, 2014
    Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventor: Marc Holtwick
  • Publication number: 20140088558
    Abstract: The present invention inter alia relates to an apparatus, comprising a detecting arrangement comprising a first and a second detecting unit, wherein the detecting arrangement is configured to at least detect a partial attaching of an attachable unit to the apparatus and a complete attaching of the attachable unit to the apparatus, wherein the attachable unit is configured to be removably attached to the apparatus, and wherein the detecting arrangement is configured to only enable at least one function of the apparatus, when a complete attaching of the attachable unit to the apparatus is detected.
    Type: Application
    Filed: May 24, 2012
    Publication date: March 27, 2014
    Inventors: Marc Holtwick, Michael Caspers, Llona Eggert
  • Publication number: 20140081215
    Abstract: A medicament delivery device comprises a housing having a longitudinal axis, a medicament delivery mechanism within the housing, a dispense interface disengagement actuator and a detachable dispense interface. The interface is moveable between a first operative position in which the dispense interface is securely engaged and at least partially contained within the housing, and a second non-operative position in which the dispense interface is partially engaged and at least partially extending from the housing such that it can be detached from the housing manually. The travel of the dispense interface from the first position to the second position is along the longitudinal axis in a direction away from the housing and the movement from the first to the second position is actuated by the dispense interface disengagement actuator.
    Type: Application
    Filed: May 24, 2012
    Publication date: March 20, 2014
    Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Marc Holtwick, Ilona Eggert, Christopher Nigel Langley, Aled Meredydd James
  • Publication number: 20140081217
    Abstract: The present invention inter-alia relates to an apparatus comprising a diaphragm valve, wherein a diaphragm of said diaphragm valve is made from a substantially rigid material, having at least partially an flexible cross-sectional shape.
    Type: Application
    Filed: May 4, 2012
    Publication date: March 20, 2014
    Applicant: SANOFI-AVENTIS DEUTSCHLAND GmbH
    Inventor: Marc Holtwick
  • Publication number: 20140066879
    Abstract: The invention is related to an apparatus comprising an inner body of a dispense interface and a manifold, wherein the inner body comprises a recess configured to receive a distal needle from a distal end of the inner body, a first fluid reservoir and a second fluid reservoir, and wherein the manifold comprises a filling block configured to redirect flow, a fluid groove arrangement configured to provide a fluid connection to the filling block, wherein the inner body and the manifold are assembled such that there is formed a channel providing a fluid connection from the first fluid reservoir and the second fluid reservoir, respectively, via the fluid groove arrangement and the filling block to the recess.
    Type: Application
    Filed: April 26, 2012
    Publication date: March 6, 2014
    Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Marc Holtwick, James Alexander Davies, Simon Lewis Bilton, David Moore, Steven Wimpenny, Christopher Nigel Langley
  • Publication number: 20140054295
    Abstract: The present invention inter alia relates to an apparatus and a method. The apparatus comprises a body part and a cover part, wherein the body part and the cover part are configured to at least partially form a fluid channel between a surface of the body part and a surface of the cover part. The surfaces of the body part and the cover part may be facing surfaces. The method comprises manufacturing the apparatus according to the present invention.
    Type: Application
    Filed: April 26, 2012
    Publication date: February 27, 2014
    Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Marc Holtwick, James Alexander Davies, Simon Lewis Bilton, David Moore, Steven Wimpenny, Christopher Nigel Langley
  • Publication number: 20140052077
    Abstract: The invention faces the technical problem of providing a tight connection between a tube and an dispense interface, while at the same time the biocompatibility of the connection can be improved. The technical problem is solved by an apparatus comprising a tube configured to guide a medium and a dispense interface. The tube comprises a first opening and a second opening, while the dispense interface comprises a recess. The recess has a first opening and a second opening and the tube is at least in part inserted into the recess. The tube is permanently affixed to the dispense interface by a combination of an interference fit and an adhesive, such that the interference fit prevents the adhesive from contaminating the medium.
    Type: Application
    Filed: April 26, 2012
    Publication date: February 20, 2014
    Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Marc Holtwick, Jeffrey Zajac, James Alexander Davies, Simon Lewis Bilton, David Moore, Steven Wimpenny, Christopher Nigel Langley
  • Publication number: 20140046267
    Abstract: The invention is related to a manifold comprising at least two valve receptacles, further comprising a fluid groove arrangement comprising at least two fluid grooves, wherein a first fluid groove of the at least two fluid grooves has a starting point near a first valve receptacle of the at least two valve receptacles and an end point near a second valve receptacle of the at least two valve receptacles and wherein a second fluid groove of the at least two fluid grooves has a starting point near a second valve receptacle of the at least two valve receptacles. The invention is further related to an apparatus comprising a manifold of the aforementioned kind and further comprising an inner body of a dispense interface.
    Type: Application
    Filed: April 26, 2012
    Publication date: February 13, 2014
    Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Marc Holtwick, James Alexander Davies, Simon Lewis Bilton, David Moore, Steven Wimpenny, Christopher Nigel Langley