Abstract: A downhole well screen has a base pipe with a filter mounted thereon with the filter comprising plurality of spaced layers including a screen layer. A longitudinally extending channel is formed in the well screen by plastically deforming the filter. The channel is selected to be of a size and shape to accommodate well control lines.

Abstract: A jumper tube for use with a shunt tube assembly comprises a first tubular member configured to engage a first shunt tube, a second tubular member axially disposed within the first tubular member, and a locking member configured to prevent the second tubular member from axially displacing into the first tubular member. The second tubular member is configured to slidingly engage within the first tubular member, and the second tubular member is configured to engage a second shunt tube.

Abstract: A method of variably restricting flow in a subterranean well can include resisting flow through a flow path, and then selectively opening a pressure barrier which previously prevented flow through another flow path. The flow paths are configured for parallel flow. A flow restrictor system for use with a subterranean well can include at least two flow paths configured for parallel flow, a flow restrictor which resists flow through one flow path, and a pressure barrier which prevents flow through another flow path. The pressure barrier is selectively openable to permit flow through the second flow path.

Abstract: This invention provides devices and methods for remodeling the female genital tissue, the device comprising a treatment tip, wherein the distal end of the treatment tip is conical, spherical, hemispherical, oval or circular in shape. The device further comprises one or more energy delivery elements for simultaneous cooling of the vaginal epithelium and transmission of energy for heating the tissues underneath the epithelium. In one embodiment, said device may further comprise one or more of the following: one or more temperature sensors for measuring the temperature at or below the epithelium; one or more directional sensors mounted on the hand piece or treatment tip; and one or more depth markers to show the depth of penetration of the treatment tip into the vagina. In another embodiment, this invention provides a device having a finger holder with electrodes for remodeling the female genital tissue.

Abstract: Disclosed are wellbore flow control devices that allow on-site field adjustments to flow characteristics. One autonomous inflow control device (AICD) assembly includes a base pipe defining one or more flow ports and an interior, at least one AICD arranged on the base pipe and having at least one fluid inlet and an outlet in fluid communication with one of the one or more flow ports, and a plug configured to be arranged in at least one of the at least one fluid inlet and the outlet of the at least one AICD by a well operator on-site.

Abstract: An assembly for restricting fluid flow into a completion string of a well and restricting fluids based on one or more fluid characteristics is presented. The assembly includes an adjustable inflow control device. The adjustable inflow control device is for restricting flow of production fluids into the completion string. The assembly also includes a first autonomous inflow control device fluidly coupled to the inflow control device for restricting fluids based on one or more fluid characteristics. Others systems and methods are presented.

Abstract: Described herein are gravel pack assemblies capable of performing complete gravel pack jobs when flow restricting devices, such as inflow control devices (“ICD”), are utilized. A gravel pack assembly includes a well screen attached to a flow restricting device and a relief valve. The relief valve is positioned in parallel with the flow restricting device so that the relief valve may provide an alternative path for fluid during dehydration of the gravel pack slurry, thus allowing extra fluid flow through the completion string during the gravel pack operation only.

Abstract: A gravel packing apparatus has first and second joints each including a sand control screen assembly having a filter medium positioned exteriorly of a base pipe and a slurry delivery subassembly positioned exteriorly of the sand control screen assembly. Each slurry delivery subassembly includes a transport tube extending longitudinally along at least a portion of the sand control screen assembly. A jumper tube extends between and is sealably coupled to the transport tube of the first joint and the transport tube of the second joint. A first locking assembly is positioned between the jumper tube and the transport tube of the first joint and a second locking assembly is positioned between the jumper tube and the transport tube of the second joint.

Abstract: A flow direction controlling layer for use in controlling the flow of fluids in subterranean well tools. The control layer comprises micro check valve arrays formed in the tool.

Abstract: This invention relates to wellbore equipment utilized in conjunction with operations performed in subterranean wells and, in particular, sand control screen assemblies providing secondary flow capabilities. Once sand control screen assembly includes a base pipe having an exterior surface and defining one or more perforations therein, a screen jacket disposed about the exterior surface of the base pipe and having a primary screen axially adjacent a secondary screen, and at least one relief valve configured to open upon experiencing a predetermined fluid pressure, wherein, once opened, the at least one relief valve diverts fluid flow from the primary screen and provides the fluid flow to the secondary screen.

Abstract: An inflow control assembly can be adjusted subsequent to manufacture and prior to being run downhole in a wellbore. The inflow control assembly can include an outer body and a chamber internal to the outer body. The chamber can define a flow path for fluid flow through the inflow control assembly when the inflow control assembly is in a wellbore traversing a subterranean formation. The flow path is injectable with a pre-determined volume of material from a source external to the outer body for reducing fluid flow through the flow path.

Abstract: Systems for simultaneously injecting and producing in a well having multiple zones. One system includes a wellbore providing first perforations extending into a first subterranean formation and second perforations extending into a second subterranean formation, a production tubing having influx ports defined therein and an annulus defined between the wellbore and the production tubing, first and second pairs of wellbore isolation devices arranged about the production tubing and axially straddling the first and second perforations to define first and second formation zones, respectively, a first bypass conduit extending between the first pair of wellbore isolation devices, a second bypass conduit extending between the second pair of wellbore isolation devices, and an injection outlet defined on the first bypass conduit for injecting a portion of the fluid into the first subterranean formation and push hydrocarbons toward the second formation zone to be produced.

Abstract: A jumper tube for use with a shunt tube assembly comprises a first tubular member configured to engage a first shunt tube, a second tubular member axially disposed within the first tubular member, and a locking member configured to prevent the second tubular member from axially displacing into the first tubular member. The second tubular member is configured to slidingly engage within the first tubular member, and the second tubular member is configured to engage a second shunt tube.

Abstract: A flow control device includes an annular inner shroud coupled to a work string that defines one or more flow ports therein, and an annular outer shroud also coupled to the work string and radially offset from the inner shroud such that a channel is defined between at least a portion of the inner and outer shrouds. The channel is in fluid communication with at least one of the one or more flow ports and configured to restrict a flow rate of a fluid. The work string has a central axis and the inner and outer shrouds extend longitudinally within the work string.

Abstract: This invention relates generally to apparatus and methods for tightening tissue of the female genitalia by heating targeted connective tissue with radiant energy, while cooling the mucosal epithelial surface over the target tissue to protect it from the heat. Embodiments include a handle and treatment tip that has both an energy delivery element and a cooling mechanism. The handle may be a two-handed handle allowing control even while rotating and maneuvering the treatment around the genital opening. The apparatus or system may also include an integrated controller, which may confirm tissue contact without applying RF energy, based only on the temperature of the applicator and the time since the last application of energy from the applicator.

Abstract: Disclosed are annular flow control devices and their methods of use. One flow control device includes an annular inner shroud coupled to a work string that defines one or more flow ports therein, and an annular outer shroud also coupled to the work string and radially offset from the inner shroud such that a channel is defined between at least a portion of the inner and outer shrouds, the channel being in fluid communication with at least one of the one or more flow ports and configured to restrict a flow rate of a fluid.

Abstract: This invention relates generally to apparatus and methods for tightening tissue of the female genitalia by heating targeted connective tissue with radiant energy, while cooling the mucosal epithelial surface over the target tissue to protect it from the heat. Embodiments include a handle and treatment tip that has both an energy delivery element and a cooling mechanism. The handle may be a two-handed handle allowing control even while rotating and maneuvering the treatment around the genital opening. The apparatus or system may also include an integrated controller, which may confirm tissue contact without applying RF energy, based only on the temperature of the applicator and the time since the last application of energy from the applicator.

Abstract: Certain aspects of the present invention are directed to a liquid valve assembly that can be disposed in a wellbore through a fluid-producing formation. The liquid valve assembly can include a housing and a liquid valve. The housing can define an inner chamber and an opening adapted to allow fluid to flow between the inner chamber and a passageway. The liquid valve can be disposed in the inner chamber. The liquid valve can include a yield stress fluid. The yield stress fluid can prevent fluid from flowing between the inner chamber and the passageway.

Abstract: The invention relates to antigen peptide derived from the Nectin4 and its use for preventing and treating cancer.

Abstract: A shunt tube assembly comprises a plurality of shunt tubes, a jumper tube, and a coupling member configured to provide fluid communication between the jumper tube and the plurality of shunt tubes. The coupling member can comprise a first end and a second end. The coupling member may be configured to provide a sealing engagement between the coupling member and the jumper tube at the first end, and the coupling member may be configured to provide a sealing engagement between the coupling member and the plurality of jumper tubes at the second end.