Abstract: Methods and compositions are disclosed for treating disorders of the contact activation system, comprising the administration of at least one C1-Inhibitor (C1-INH) and at least one Factor XII (FXII) inhibitor.

Abstract: The present invention relates to the use of a direct Factor XII (FXII) inhibitor in the treatment of a neurotraumatic disorder resulting from a traumatic injury of the brain (traumatic brain injury, TBI) or the spinal cord (spinal cord injury, SCI).

Abstract: The invention relates to an agrochemical composition comprising the potassium salt of dicamba and an adjuvant selected from a) a polyalkylene oxide block-copolymer, b) a hyperbranched polycarbonate, and c) a solvent selected from C1-C6-alkyl lactate, C3-C6-lactone and N—C1-C15-alkyl pyrrolidone. It also relates to a method of controlling undesired vegetation, and/or for regulating the growth of plants, wherein the agrochemical composition is allowed to act on the respective pests, their environment, or the crop plants to be protected from the respective pest, on the soil and/or on the crop plants and/or on their environment; to a method for producing the agrochemical composition; to an adjuvant composition for increasing the solubility of the potassium salt of dicamba in an aqueous composition comprising a mixture of additive a) or additive b) with additive c) fine droplet formation.

Abstract: The invention relates to an agrochemical composition comprising a salt of dicamba and an N—C2-C15-alkyl pyrrolidone. It also relates to a method of controlling undesired vegetation, and/or for regulating the growth of plants, wherein the agrochemical composition is allowed to act on the respective pests, their environment, or the crop plants to be protected from the respective pest, on the soil and/or on the crop plants and/or on their environment; to a method for producing the agrochemical composition; to an adjuvant composition for increasing the solubility of the salt of dicamba in an aqueous composition comprising an N—C2-C15-alkyl pyrrolidone.

Abstract: Agrochemical aqueous formulations comprising A) An agriculturally acceptable salt of dicamba, B) At least one anionic surfactant that comprises at least one naphthalene sulfonate C) an aqueous solvent, D) Optionally at least one thickener, E) Optionally other pesticides, F) Optionally other formulation auxiliaries.

Abstract: The present invention relates to a salt comprising an anionic pesticide (A) and a cationic polyamine of the formula (B) as described in the description. The invention further relates to an agrochemical composition comprising said salt. It also relates to a method for preparing said salt comprising combining the pesticide in its neutral form or as salt, and the polyamine in its neutral form or as salt. In addition, the invention relates to a method of combating harmful insects and/or phytopathogenic fungi. It also relates to a method of controlling undesired vegetation. Finally, the invention relates to seed comprising said salt.

Abstract: The invention relates to an inhibitor of Factor XII (FXII) for use in treating or preventing chronic kidney disease, renal fibrosis, glomerulosclerosis, renal scarring, ischemia/reperfusion injury in native or transplant kidneys and/or acute kidney injury, a kit for use in treating or preventing chronic kidney disease, renal fibrosis, glomerulosclerosis, renal scarring, ischemia/reperfusion injury in native or transplant kidneys, acute kidney injury, renal fibrosis as a result of rejection of a kidney transplant/allograft, and/or fibrosis of a kidney transplant/allograft as a result of rejection or recurrent underlying disease comprising one inhibitor of Factor XII, and an anti-Factor XII (FXII) antibody or antigen binding fragment thereof for use in treating or preventing chronic kidney disease, renal fibrosis, glomerulosclerosis, renal scarring, ischemia/reperfusion injury in native or transplant kidneys and/or acute kidney injury comprising one inhibitor of Factor XII.

Abstract: The invention relates to inhibitory anti-factor XII/FXIIa antibodies and methods of their use.

Abstract: The present invention relates to a portable spraying device (1) for discharging a fluid, in particular an agricultural formulation, having a container (2) for holding the fluid, a pump (15), which is in fluid connection with the container (2), for pumping the fluid out of the container (2), a spray gun (21), which comprises a spray opening (27) and an electrically controllable application valve (20) for opening and closing a passage to the spray opening (27), an application line (17), which establishes a fluid connection between the pump (15) and the spray gun (21).

Abstract: The present invention relates to a contact activation system inhibitor, preferably a C1INH, for use in the treatment and/or prevention of remote ischemia-reperfusion injury (IRI), comprising administering the contact activation system inhibitory to an individual.

Abstract: The invention relates to an inhibitor of Factor XII (FXII) for use in treating or preventing chronic kidney disease, renal fibrosis, glomerulosclerosis, renal scarring, ischemia/reperfusion injury in native or transplant kidneys and/or acute kidney injury, a kit for use in treating or preventing chronic kidney disease, renal fibrosis, glomerulosclerosis, renal scarring, ischemia/reperfusion injury in native or transplant kidneys, acute kidney injury, renal fibrosis as a result of rejection of a kidney transplant/allograft, and/or fibrosis of a kidney transplant/allograft as a result of rejection or recurrent underlying disease comprising one inhibitor of Factor XII, and an anti-Factor XII (FXII) antibody or antigen binding fragment thereof for use in treating or preventing chronic kidney disease, renal fibrosis, glomerulosclerosis, renal scarring, ischemia/reperfusion injury in native or transplant kidneys and/or acute kidney injury comprising one inhibitor of Factor XII.

Abstract: The present invention relates to a portable spraying device (1) for discharging a fluid, in particular an agricultural formulation, having a container (2) for holding the fluid, a pump (15), which is in fluid connection with the container (2), for pumping the fluid out of the container (2), a spray gun (21), which comprises a spray opening (27) and an electrically controllable application valve (20) for opening and closing a passage to the spray opening (27), an application line (17), which establishes a fluid connection between the pump (15) and the spray gun (21).

Abstract: The present invention relates to the use of a direct Factor XII (FXII) inhibitor in the treatment of a neurotraumatic disorder resulting from a traumatic injury of the brain (traumatic brain injury, TBI) or the spinal cord (spinal cord injury, SCI).

Abstract: Methods and compositions are disclosed for treating disorders of the contact activation system, comprising the administration of at least one C1-Inhibitor (C1-INH) and at least one Factor XII (FXII) inhibitor.

Abstract: The present invention relates to clinically relevant dosing regimens of prophylactic subcutaneously administered long-acting factor IX (i.e., human FIX fused to human albumin) in human patients.

Abstract: The invention relates to inhibitory anti-factor XII/FXIIa antibodies and methods of their use.

Abstract: The invention relates to inhibitory anti-factor XII/FXIIa antibodies and methods of their use.

Abstract: A method for controlling unwanted vegetation including the application of a water-insoluble herbicide and a soil mobilizer to a soil. The weight ratio of the herbicide to the soil mobilizer is from 1:0.8 to 1:50, and the soil mobilizer is of the formula I as defined in the disclosure. Also disclosed is a composition including a water-insoluble herbicide and the soil mobilizer. The weight ratio of the herbicide to the soil mobilizer is from 1:0.8 to 1:50. A use of the soil mobilizer for enhancement of the herbicidal activity of a herbicide applied to soil is disclosed.

Abstract: The present invention relates to microcapsules comprising a core, wherein the core comprises cinmethylin, and a polyurea shell, wherein the shell comprises a polyaddition product of diphenylmethane diisocyanate or an oligomer thereof and at least one amine having at least two primary amino groups; to a composition comprising such microcapsules; to a method for preparing such microcapsules or such a composition; to a composition obtainable by said preparation method; and to the use of such microcapsules or compositions for controlling undesired vegetation.

Abstract: The present invention relates to a composition comprising microcapsules, wherein the micro-capsules comprise a polyurea shell and a core, wherein the core comprises cinmethylin and the shell comprises a polymerization product of a tetramethylxylylene and an aliphatic diamine diisocyanate, and, optionally, a cycloaliphatic diisocyanate; to a method for preparing the composition comprising the steps of contacting water, cinmethylin, the diisocyanate and the aliphatic diamine; and to a method of controlling undesired plant growth and/or for regulating the growth of plants, wherein the composition is allowed to act on the soil and/or on undesired plants and/or on the crop plants and/or on their environment.