Abstract: The invention relates to inhibitory anti-factor XII/FXIIa antibodies and methods of their use.

Abstract: The invention relates to inhibitory anti-factor XII/FXIIa antibodies and methods of their use.

Abstract: Silent brain ischemia (SBI) or ischemia of other organs can result from an embolism that is introduced into the arterial system during a medical procedure. The application provides a method of administering a FXII inhibitor in a patient receiving a medical procedure and animal models useful for studying ischemia including SBI and ischemia in other organs, and for evaluating candidate therapeutics.

Abstract: The invention relates to inhibitory anti-factor XII/FXIIa antibodies and methods of their use.

Abstract: The present invention relates to an aqueous composition comprising dicamba and a drift control agent; to a method for preparing a tank mix, which comprises the step of contacting water and said composition, and optionally further pesticides; to a method of controlling phytopathogenic fungi and/or undesired vegetation and/or unde-sired insect or mite attack and/or for regulating the growth of plants, wherein the composition is allowed to act on the respective pests, their environment or the plants to be protected from the respective pest, on the soil and/or on undesired plants and/or the crop plants and/or their environment; and finally to a use of the alkoxylate of the formula (I) as defined below for reducing the wind drift of an aqueous composition comprising a pesticide.

Abstract: The subject of the present invention is, in the most general aspect, the prevention and/or treatment of a secondary edema. In particular, the present invention relates to a C1-Inhibitor for use in a method of preventing the formation and/or reducing the size of a secondary edema of the central nervous system (CNS) in a subject wherein the subject has or has had at least one disorder selected from the group consisting of stroke, ischemic stroke, hemorrhagic stroke, perinatal stroke, traumatic brain injury and spinal cord injury. Preferably the secondary edema of the CNS is a secondary brain edema. Another subject of the present invention is the treatment of disorders associated with an increased permeability of the blood brain barrier or the blood spinal cord barrier. And a third subject is a plasma-derived C1-inhibitor for use in a method of preventing, reducing or treating brain ischemia-reperfusion injury.

Abstract: An inhibitor of FXII/FXIIa for the prevention of the formation and/or stabilization of thrombi during and/or after a medical procedure performed on a human or animal subject comprising contacting blood of said human or animal subject with artificial surfaces, wherein said inhibitor of FXII/FXIIa is administered before and/or during and/or after said medical procedure.

Abstract: The present invention relates to a composition comprising a pesticide and an alkoxylate. Moreover, the invention relates to the alkoxylate, to a process for its preparation and to its use as adjuvant in pesticide-comprising spray mixtures. The invention furthermore relates to a method of controlling phytopathogenic fungi and/or undesired vegetation and/or undesired insect or mite attack and/or for regulating the growth of plants, wherein the composition is allowed to act on the respective pests, their environment or the plants to be protected from the respective pest, on the soil and/or on undesirable plants and/or the crop plants and/or their environment. Furthermore, the invention relates to seed comprising the composition.

Abstract: The present invention relates to a method for enhancing the performance of a pesticide comprising the step of contacting an adjuvant and the pesticide, wherein the pesticide is present in a concentration of less than 10 wt % in the resulting composition containing the adjuvant and the pesticide, and wherein the adjuvant contains a guanidine of formula (A) as defined below, and/or a salt thereof. The invention also relates to a composition comprising an auxin-herbicide and said adjuvant; to a use of said adjuvant for enhancing the performance of a pesticide; and to a method of controlling undesired vegetation, which comprises allowing a herbicidal effective amount of said composition to act on plants, their habitat or on seed of said plants.

Abstract: The present invention relates to an adjuvant comprising a sugar-based surfactant; a drift control agent and/or a humectant; and an alkoxylate, wherein the alkoxylate is an amine alkoxylate (A) or a quaternized derivative (AQ) of the amine alkoxylate (A) as defined below. It further relates to a method of preparing said adjuvant by contacting the sugar-based surfactant; the drift control agent and/or the humectant; and the amine alkoxylate (A) or the quaternized derivative (AQ) of the amine alkoxylate (A); and to a method of controlling phytopathogenic fungi and/or undesired vegetation and/or undesired insect or mite attack and/or for regulating the growth of plants, wherein the tank mix according is allowed to act on the respective pests, their environment or the plants to be protected from the respective pest, on the soil and/or on undesired plants and/or the crop plants and/or their environment.

Abstract: The present invention relates to an aqueous composition comprising dicamba and a drift control agent; to a method for preparing a tank mix, which comprises the step of contacting water and said composition, and optionally further pesticides; to a method of controlling phytopathogenic fungi and/or undesired vegetation and/or unde-sired insect or mite attack and/or for regulating the growth of plants, wherein the composition is allowed to act on the respective pests, their environment or the plants to be protected from the respective pest, on the soil and/or on undesired plants and/or the crop plants and/or their environment; and finally to a use of the alkoxylate of the formula (I) as defined below for reducing the wind drift of an aqueous composition comprising a pesticide.

Abstract: The present invention relates to an aqueous composition comprising at least 200 g/l of an anionic pesticide and at least 50 g/l of an inorganic base. It further relates to a method for preparing the composition comprising the step of contacting the anionic pesticide and the inorganic base; a method of combating harmful insects and/or phytopathogenic fungi, which comprises contacting plants, seed, soil or habitat of plants in or on which the harmful insects and/or phytopathogenic fungi are growing or may grow, plants, seed or soil to be protected from attack or infestation by said harmful insects and/or phytopathogenic fungi with an effective amount of the composition; and to a method of controlling undesired vegetation, which comprises allowing a herbicidal effective amount of the composition to act on plants, their habitat or on seed of said plants.

Abstract: The present invention relates to a method for preparing a tank mix, which comprises the step of contacting a pesticide formulation, water, and a tank mix adjuvant which comprises a polypropylene glycol and a triblock polymer comprising at least one polyethyleneoxide moiety and at least one polypropyleneoxide moiety; to the tank mix adjuvant; to a pesticide formulation comprising the tank mix adjuvant: to a method of controlling phytopathogenic fungi and/or undesired vegetation and/or undesired insect or mite attack and/or for regulating the growth of plants, wherein the tank mix is allowed to act on the respective pests, their environment or the plants to be protected from the respective pest, on the soil and/or on undesired plants and/or the crop plants and/or their environment, and to a use of the tank mix adjuvant or reducing the wind drift of a pesticide formulation.

Abstract: The present invention relates to a method for controlling arthropods comprising the application of an aqueous gel which contains an insecticide, an attractant and a thickener, wherein the aqueous gel is applied in the form of spots on fruit trees. The invention further relates to an aqueous gel comprising an insecticide, an attractant, a thickener, a humectant and a feeding stimulant. The invention also relates to a concentrated gel for preparing the aqueous gel.

Abstract: The present invention relates to a method for preparing a tank mix, which comprises the step of contacting a glyphosate formulation, water, and a tank mix adjuvant, wherein the tank mix adjuvant comprises a base selected from a carbonate or an alkali salt of a phosphate, and wherein the tank mix adjuvant is present in form of an aqueous liquid, which contains at least 50 g/l of the base, or in form of a particulate solid, which contains at least 10 wt % of the base, wherein the tank mix has a tank mix acidity of at least pH 8.0, and wherein the tankmix contains at least 50 wt % water. The invention also relates to a method of controlling phytopathogenic fungi and/or undesired vegetation and/or undesired insect or mite attack and/or for regulating the growth of plants, wherein the tank mix is allowed to act on the respective pests, their environment or the plants to be protected from the respective pest, on the soil and/or on undesired plants and/or the crop plants and/or their environment.

Abstract: The present invention relates to q method for preparing a tank mix, which comprises the step of contacting a pesticide formulation, water, and a tank mix adjuvant, wherein the tank mix adjuvant comprises a base, which contains a mixture of an alkali salt of carbonate and an alkali salt of hydrogencarbonate, and wherein the tank mix adjuvant is present in form of an aqueous liquid, which contains at least 50 g/l of the base, or in form of a particulate solid, which contains at least 10 wt % of the base.

Abstract: The present invention relates to q method for preparing a tank mix, which comprises the step of contacting a pesticide formulation, water, and a tank mix adjuvant, wherein the tank mix adjuvant comprises a base selected from a carbonate and/or a phosphate, and wherein the tank mix adjuvant is present in form of a particulate solid, which contains at least 10 wt % of the base.

Abstract: The present invention relates to a method for preparing a tank mix, which comprises the step of contacting a pesticide formulation, water, and a tank mix adjuvant, wherein the tank mix adjuvant comprises an alkyl polyglucoside and a base selected from a carbonate and/or a phosphate, and wherein the tank mix adjuvant is present in form of an aqueous liquid, which contains at least 50 g/l of the base, or in form of a particulate solid, which contains at least 10 wt % of the base.

Abstract: This application relates to neurological inflammatory diseases, such as multiple sclerosis, and to methods of administering a Factor XII inhibitor to prevent, treat, or otherwise ameliorate the effects of a neurological inflammatory disease, such as multiple sclerosis. Agents and pharmaceutical compositions comprising agents which inhibit the activity of FXII are also provided.

Abstract: The subject of the present invention is, in the most general aspect, the prevention and/or treatment of a secondary edema. In particular, the present invention relates to a C1-Inhibitor for use in a method of preventing the formation and/or reducing the size of a secondary edema of the central nervous system (CNS) in a subject wherein the subject has or has had at least one disorder selected from the group consisting of stroke, ischemic stroke, hemorrhagic stroke, perinatal stroke, traumatic brain injury and spinal cord injury. Preferably the secondary edema of the CNS is a secondary brain edema. Another subject of the present invention is the treatment of disorders associated with an increased permeability of the blood brain barrier or the blood spinal cord barrier. And a third subject is a plasma-derived C1-inhibitor for use in a method of preventing, reducing or treating brain ischemia-reperfusion injury.