Patents by Inventor Marcel Hibert

Marcel Hibert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-inflammatory and protein kinase inhibitor compositions and related methods for downregulation of detrimental cellular responses and inhibition of cell death
    Publication number: 20030176437
    Abstract: A novel class of pyridazine compositions and related methods of use.
    Type: Application
    Filed: September 3, 2002
    Publication date: September 18, 2003
    Inventors: D.M. Watterson, Anu R. Sawkar, Thomas J. Lukas, Salida Mirzoeva, Linda J. Van Eldik, Marcel Hibert, Anastasia Velentza, Magdalena Zasadzki, Jacques Haiech, Jean-Jacques Bourguignon
  • Use of certain esters of hexahydro-8-hydroxy-2,6-methano-2H-quinolozin-3(4H)-one and related compounds for treating cognitive disorders
    Patent number: 5910501
    Abstract: This invention relates to the manufacture of certain esters of hexahydro-8-hydroxy-2,6-methano-2H-quinolizin-3(4H)-one and hexahydro-8-hydroxy-2,6-methano-2H-quinolizines and their use as medicaments in the treatment of cognitive disorders.
    Type: Grant
    Filed: August 26, 1997
    Date of Patent: June 8, 1999
    Assignee: Merrell Pharmaceuticals Inc.
    Inventors: Maurice W. Gittos, Marcel Hibert
  • 5H-Dibenzo (A,D) cycloheptenes as muscarinic receptor antagonists
    Patent number: 5508280
    Abstract: This invention relates to novel derivatives of 5H-dibenzo (a,d)cycloheptenes, to the processes for their preparation, to their muscarinic receptor antagonist properties and to their end-use application for treating Parkinson's Disease, tardive dyskinesia, and motion sickness.
    Type: Grant
    Filed: January 30, 1995
    Date of Patent: April 16, 1996
    Assignee: Merrell Pharmaceuticals, Inc.
    Inventors: Marcel Hibert, Luc Van Hijfte, Mary Richards, Paul Moser
  • Certain pharmaceutically active 6H-imidazo[1,2-a]pyridine-5-ones
    Patent number: 5109006
    Abstract: This invention relates to novel derivatives of 1,7'-[imidazo-[1,2-a]pyridine]5'-(6'H)ones, to the method for their preparation and to their use as anti-hypertensive, anxiety, anti-depressant and anti-migraine agents, and to their use as appetite regulators useful for the treatment of anorexia and obesity.
    Type: Grant
    Filed: August 22, 1991
    Date of Patent: April 28, 1992
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventor: Marcel Hibert
  • Aromatic 2-aminoalkyl-1,2-benzoisothiazol-3(2H)one-1,1-dioxide derivatives
    Patent number: 4954500
    Abstract: This invention relates to aromatic 2-aminoalkyl derivatives of 1,2-benzoisothiazol-3(2H)one-1,1-dioxides, processes for the preparation of same, and to their use as anxiolytic and antihypertensive agents.
    Type: Grant
    Filed: February 2, 1990
    Date of Patent: September 4, 1990
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Marcel Hibert, Maurice W. Gittos
  • Aromatic 2-aminoalkyl-1,2-benzoisothiazol-3(2H)-one-1,1-dioxide
    Patent number: 4857526
    Abstract: This invention relates to aromatic 2-aminoalkyl derivatives of 1,2-benzoisothiazol-3(2H)one-1,1-dioxides, processes for the preparation of same, and to their use as anxiolytic and antihypertensive agents.
    Type: Grant
    Filed: September 12, 1988
    Date of Patent: August 15, 1989
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Marcel Hibert, Maurice W. Gittos
  • Aromatic 2-aminoalkyl-1,2-benzoisothiazol-3(2H)one-1,1-dioxide derivatives, usefull as anxiolytic agents
    Patent number: 4789676
    Abstract: This invention relates to aromatic 2-aminoalkyl derivatives of 1,2-benzoisothiazol-3(2H)one-1,1-dioxides, processes for the preparation of same, and to their use as anxiolytic and antihypertensive agents.
    Type: Grant
    Filed: February 22, 1988
    Date of Patent: December 6, 1988
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Marcel Hibert, Maurice W. Gittos
  • Aromatic 2-aminoalkyl-1,2-benzoisothiazol-3(2H)one-1,1-dioxide derivatives and their use as anti-hypertensive and anxiolytic agents
    Patent number: 4748182
    Abstract: This invention relates to aromatic 2-aminoalkyl derivatives of 1,2-benzoisothiazol-3(2H)one-1,1-dioxides, processes for the preparation of same, and to their use as anxiolytic and antihypertensive agents.
    Type: Grant
    Filed: March 5, 1986
    Date of Patent: May 31, 1988
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Marcel Hibert, Maurice W. Gittos
  • Aromatic omega-alkyl-imino-tetrahydro-6H-1,3-thiazin-6-one derivatives
    Patent number: 4704389
    Abstract: This invention relates to aromatic .omega.-alkylimino-tetrahydro-6H-1,3-thiazine-6-one derivatives, to a process for the preparation of same, and to their use as anxiolytic and antihypertensive agents.
    Type: Grant
    Filed: January 16, 1987
    Date of Patent: November 3, 1987
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Maurice W. Gittos, Marcel Hibert
  • 4-(2-pyrimidinyl)-1-piperazinyl heterocyclic carbonyl derivatives
    Patent number: 4696927
    Abstract: This invention relates to 4-(2-pyrimidinyl)-1-piperazinyl heterocyclic carbonyl derivatives, to a process for their preparation, and to their use as anxiolytic agents.
    Type: Grant
    Filed: December 17, 1986
    Date of Patent: September 29, 1987
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Maurice W. Gittos, Marcel Hibert
  • Glutarimide antianxiety and antihypertensive agents
    Patent number: 4612312
    Abstract: Glutarimide derivatives of the formula which are useful antihypertensive and antianxiety agents ##STR1## wherein R.sub.1 and R.sub.2 each independently represent hydrogen, a 1 to 4 carbon alkyl, a 1 to 4 carbon alkoxy, halogen, nitro, hydroxy, SO.sub.3 H, SO.sub.2 NH.sub.2, and when R.sub.1 and R.sub.2 are taken together, form a fused phenyl group at the 1,2- or 3,4- positions, with the proviso that when R.sub.1 and R.sub.2 are identical they each represent a hydrogen, a 1 to 4 carbon alkyl, a 1 to 4 carbon alkoxy, hydroxy or a halogen group; A and B independently represent an oxo, a thio or an imino group having the formula --N(R.sub.6)-- wherein the R.sub.6 group is hydrogen or a 1 to 4 carbon alkyl group; R.sub.3 is a hydrogen, a 1 to 4 carbon alkyl or hydroxyethyl group; n is an integer of from 2 to 5; and R.sub.4 and R.sub.5 represent methyl groups or when taken together form a cyclopentane or cyclohexane ring; its enantiomers; and the pharmaceutically acceptable acid addition salts thereof.
    Type: Grant
    Filed: June 13, 1985
    Date of Patent: September 16, 1986
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Marcel Hibert, Maurice W. Gittos