Abstract: A connector device for connecting two containers with first and second members slidably displaceable in regard to each other along an axis between a first and a second position is presented. The first member comprises a needle parallel to the axis so that the first container's septum is penetrated by one end of the needle when the first container is introduced into the first member. The second member comprises a coupling to the second container. The other needle end penetrates the second container's septum when the members are in the second position establishing a connection between the two containers. The first member comprises a coupling to the second container coupled to the second member. The first member can couple to the second container when the two members are in the second position and cannot couple to the second container when the two members are in the first position.

Abstract: A system is configured to create or enlarge a cavity in a tissue body and generally includes a cannula, a friction reduction covering, and a cavity creation member. The cavity creation member includes an end portion that is configured to transition between a first shape and a second shape that is different from the first shape. In operation, retracting the friction reduction covering relative to end portion causes the end portion to change shape from the first shape to the second shape such that the cavity creation member is configured to create or enlarge a cavity in the tissue body as the second end portion exits the friction reduction member.

Abstract: A system to stabilize and guide the growth of the spinal column includes an elongated support member having a width and a length and a guiding connector having a bone connecting portion and a guiding portion. The bone connecting portion secures the guiding connector to a vertebrae and the guiding portion has a bearing element with a passageway adapted to receive the elongated support member. The bearing element permits relative sliding movement of the elongated support element in the passageway of the bearing element. The system may further include a bone fixation element has an elongated support member receiving channel, a locking mechanism and a bone anchoring portion. The bone anchoring portion secures the bone fixation element to bone. The locking mechanism secures the elongated support member in the channel. The guiding connector is moveable along the elongated support member to permit and control the growth of the spinal column along a predetermined path.

Abstract: A connector device for connecting two containers with first and second members slidably displaceable in regard to each other along an axis between a first and a second position is presented. The first member comprises a needle parallel to the axis so that the first container's septum is penetrated by one end of the needle when the first container is introduced into the first member. The second member comprises a coupling to the second container. The other needle end penetrates the second container's septum when the members are in the second position establishing a connection between the two containers. The first member comprises a coupling to the second container coupled to the second member. The first member can couple to the second container when the two members are in the second position and cannot couple to the second container when the two members are in the first position.

Abstract: A system to stabilize and guide the growth of the spinal column includes an elongated support member having a width and a length and a guiding connector having a bone connecting portion and a guiding portion. The bone connecting portion secures the guiding connector to a vertebrae and the guiding portion has a bearing element with a passageway adapted to receive the elongated support member. The bearing element permits relative sliding movement of the elongated support element in the passageway of the bearing element. The system may further include a bone fixation element has an elongated support member receiving channel, a locking mechanism and a bone anchoring portion. The bone anchoring portion secures the bone fixation element to bone. The locking mechanism secures the elongated support member in the channel. The guiding connector is moveable along the elongated support member to permit and control the growth of the spinal column along a predetermined path.

Abstract: In one embodiment, a method of filling a container with a liquid drug from a drug reservoir may include: a) connecting a container and a drug reservoir with a cannula such that the drug reservoir and the container fluidically communicate with each other via the cannula, while being hermetically sealed; b) reducing a first volume contained within the container to displace a gaseous medium from the first volume of the container via the cannula into a second volume contained within the drug reservoir; c) increasing the first volume of the container to displace the liquid drug from the second volume of the drug reservoir into the first volume of the container to fill the container; and d) disconnecting the container and the drug reservoir. Before performing action d), action b) and action c) can be successively performed more than once to stepwise increase an amount of liquid drug displaced.

Abstract: In one embodiment, a method of filling a container with a liquid drug from a drug reservoir may include: a) connecting a container and a drug reservoir with a cannula such that the drug reservoir and the container fluidically communicate with each other via the cannula, while being hermetically sealed; b) reducing a first volume contained within the container to displace a gaseous medium from the first volume of the container via the cannula into a second volume contained within the drug reservoir; c) increasing the first volume of the container to displace the liquid drug from the second volume of the drug reservoir into the first volume of the container to fill the container; and d) disconnecting the container and the drug reservoir. Before performing action d), action b) and action c) can be successively performed more than once to stepwise increase an amount of liquid drug displaced.

Abstract: A filling device is described which is configured to control the process of filling a medical or therapeutic fluid from a supply container containing the medical or therapeutic fluid into an administration container that is in fluid connection with the supply container. The filling device includes a volume control system configured to control the volume of the administration container and a pressure detection system configured to detect a pressure value related to the pressure inside the supply container. The filling device is further configured to perform the process steps of filling the administration container by: directing the volume control system to decrease the volume of the administration container, directing the pressure detection system to detect a pressure value, and directing the volume control system to increase the volume of the administration container if an increase criterion depending on the pressure value is fulfilled.

Abstract: Included are embodiments of an infusion set for administering a liquid. One embodiment includes an infusion head to be placed on the tissue of a patient, a coupler for connecting the infusion head to an administering device, and a cannula that is configured for connection to the infusion head. Some embodiments include a display device for displaying an application period of at least a portion of the liquid administered using the infusion set.

Abstract: Included are embodiments of an infusion set for administering a liquid. One embodiment includes an infusion head to be placed on the tissue of a patient, a coupler for connecting the infusion head to an administering device, and a cannula that is configured for connection to the infusion head. Some embodiments include a display device for displaying an application period of at least a portion of the liquid administered using the infusion set.

Abstract: A device for moving a piston inside a cartridge having a cartridge body and the piston displaceable along a longitudinal axis of the cartridge body is presented. The device comprises a first portion having first coupler for coupling the cartridge body to the first portion such that in both directions of the longitudinal axis, a connection exists between the cartridge body and the first portion; and a second portion having second coupler for coupling the piston to the second portion such that in both directions of the longitudinal axis, a connection exists between the piston and the second portion. The first and second portions move relative to each other to effect at least a forward displacement of the piston coupled to the second portion inside the cartridge body coupled to the first portion along the longitudinal axis. The second coupler establishes and releases the connection with the piston.

Abstract: A method of preparing at least part of a medical device for application and a medical assembly for preparing or storing the at least one disposable unit of the medical device is presented. The medical assembly comprises a chemical or physical monitoring device for counting and/or displaying a time period of application and/or time remaining before required disposal or replacement of the disposable unit. The monitoring device is automatically activated by moving the at least one disposable unit relative to a second unit of the medical assembly for preparing or positioning the disposable unit for use with the medical device; assembling the at least one disposable unit and the medical device; and/or withdrawing the disposable unit of a storage compartment of the second unit.

Abstract: A connector device for connecting two containers with first and second members slidably displaceable in regard to each other along an axis between a first and a second position is presented. The first member comprises a needle parallel to the axis so that the first container's septum is penetrated by one end of the needle when the first container is introduced into the first member. The second member comprises a coupling to the second container. The other needle end penetrates the second container's septum when the members are in the second position establishing a connection between the two containers. The first member comprises a coupling to the second container coupled to the second member. The first member can couple to the second container when the two members are in the second position and cannot couple to the second container when the two members are in the first position.

Abstract: Devices and methods are disclosed which automatically reconstitute a drug, such as e.g., a lyophilized drug. A vial (30) containing the drug is fluidly coupled to a cartridge (12) containing a reconstitution liquid with a fluid conduit (14f), wherein an entry point is defined where the fluid conduit enters the vial (30). The device (10) automatically adjusts orientation of the vial (30) such that the entry point of the vial is gravitationally higher than the drug in the vial (30), and automatically transfers the reconstitution liquid out of the cartridge (12) and into the vial (30) to create a reconstituted drug. The device (10) also automatically adjusts the orientation of the vial (30) such that the entry point of the vial is gravitationally lower than the reconstituted drug, and automatically transfers the reconstituted drug from the vial (30) and into the cartridge (12).

Abstract: In one embodiment, a method of filling a container with a liquid drug from a drug reservoir may include: a) connecting a container and a drug reservoir with a cannula such that the drug reservoir and the container fluidically communicate with each other via the cannula, while being hermetically sealed; b) reducing a first volume contained within the container to displace a gaseous medium from the first volume of the container via the cannula into a second volume contained within the drug reservoir; c) increasing the first volume of the container to displace the liquid drug from the second volume of the drug reservoir into the first volume of the container to fill the container; and d) disconnecting the container and the drug reservoir. Before performing action d), action b) and action c) can be successively performed more than once to stepwise increase an amount of liquid drug displaced.

Abstract: A system to stabilize and guide the growth of the spinal column includes an elongated support member having a width and a length and a guiding connector having a bone connecting portion and a guiding portion. The bone connecting portion secures the guiding connector to a vertebrae and the guiding portion has a bearing element with a passageway adapted to receive the elongated support member. The bearing element permits relative sliding movement of the elongated support element in the passageway of the bearing element. The system may further include a bone fixation element has an elongated support member receiving channel, a locking mechanism and a bone anchoring portion. The bone anchoring portion secures the bone fixation element to bone. The locking mechanism secures the elongated support member in the channel. The guiding connector is moveable along the elongated support member to permit and control the growth of the spinal column along a predetermined path.

Abstract: Included are embodiments of an infusion set for administering a liquid. One embodiment includes an infusion head to be placed on the tissue of a patient, a coupler for connecting the infusion head to an administering device, and a cannula that is configured for connection to the infusion head. Some embodiments include a display device for displaying an application period of at least a portion of the liquid administered using the infusion set.

Abstract: An extrusion die assembly has a body member which rotatably houses a barrel member which provides a tubular passage. The body member has an inlet channel for passage of a plasticized, especially edible, substance to the barrel member tubular passage which extends from a junction with the body member to at least one outlet channel. A rotary seal is provided at a junction between the body member and barrel member.