Abstract: Embolization, as well as related particles and methods, are described.

Abstract: An implantable port for accessing internal body structures, the port comprises a proximal housing including an opening providing access to an interior of the port and a distal housing adapted for assembly with the proximal housing, the distal housing including a reservoir which, when the distal housing is mated with the proximal housing is in fluid communication with the opening of the proximal housing in combination with a radiopaque element in one of the proximal and distal housings, a shape of the radiopaque element identifying, when imaged, a structural characteristic of the port not otherwise identifiable visually.

Abstract: Embolic polymer particles are described.

Abstract: Described herein are various implant delivery methods and systems that include an implantable medical device secured to a pusher wire with biomaterial. The biomaterial is selected to controllably decouple the implantable medical device from the pusher wire after exposure to a flushing agent.

Abstract: Described herein is a coil anchor having an anchor body configured for placement within a large diameter blood vessel, wherein the anchor body includes a radially expandable sidewall, a proximal opening dimensioned to receive an embolic coil, and a distal opening dimensioned to permit blood flow within the blood vessel. The coil anchor further includes at least one coil retaining element configured to retain the embolic coil within the blood vessel while permitting blood flow within the blood vessel.

Abstract: Described herein are various implant delivery systems and methods of use. The systems can include an implantable medical device mated to a pusher wire via a detachable link. The user can detach the detachable link by rotating the pusher wire. For example, the detachable link can include first and second interlocking members, where the first interlocking member including a male mating surface and the second interlocking member including a female mating surface. The first and second body members can be mechanically interlocked, for example, with a pin and a slot.

Abstract: Described herein are various implant delivery methods and systems that include a detachable link for connecting an implantable device and a control wire. The detachable link can include an elongate body comprising a first arm with a mating surface having a slot extending the width of the elongate body and a second arm having a mating surface that includes a extension portion adapted to mate with the slot. A guide member can extend between the first and second arms and inhibit relative transverse and/or rotational movement between the first and second arms.

Abstract: A drug delivery particle including a reservoir region having primarily large pores and a metering region. The particle can be highly spherical.

Abstract: The present invention includes an introducer sheath. The sheath may comprise a first proximal elongated section having a first outer diameter and a first inner diameter, and a main body elongated section having a second inner diameter and a second outer diameter, wherein the second outer diameter is larger than the first outer diameter. The sheath may further include a distal section having an outer wall that tapers from the second outer diameter of the main body elongated section to a smaller distal outer diameter.

Abstract: Disclosed herein are various systems and methods for delivering implantable devices, such as, for example detachable embolic coils. The systems can include an embolic coil mated to a pusher wire via a detachable link comprising first and second engaging members and an expandable member or a sleeve. The expandable member or sleeve can reduce relative movement between the engaging members to inhibit premature detachment and/or jamming of the detachable link as the embolic coil is delivered through a catheter.

Abstract: Embolization, as well as related particles and methods, are described.

Abstract: A resection device includes an elongated probe shaft and a tissue resection member disposed at a distal end of the elongated probe shaft. The tissue resection member has a cutting surface configured for being placed in contact with tissue. In one aspect of the invention, at least one ejection port is located adjacent to the cutting surface of the tissue resection member, wherein the at least one ejection port is coupled to a source of a polymerizable hemostasis-promoting material that is delivered to the resection site of interest. In certain embodiments, polymerization of the hemostasis-promoting material may be accelerated by application of heat, radiofrequency energy, or ultra violet light.

Abstract: Embolization, as well as related particles and methods, are described.

Abstract: A delivery catheter for delivering material(s) into the body of a mammal can include a first elongated member and a second elongated member. At least a portion of the second elongated member can be slidably disposed within a lumen of the first elongated member. The delivery catheter can mix two materials and then introduce the mixed materials into the body of a mammal.

Abstract: Coils, such as embolic coils, and related methods, devices, and compositions, are disclosed.

Abstract: Coils, such as embolic coils, and related methods, devices, and compositions, are disclosed.

Abstract: Coils, such as embolic coils, and related methods, devices, and compositions, are disclosed.

Abstract: Embolic coil introducer sheath locking mechanisms, as well as related components, systems and methods are disclosed.

Abstract: Coil assemblies and related components and methods are disclosed. The coil assemblies can include two or more embolic coils having one or more different coil parameters.

Abstract: A method of treating tissue includes placing substantially spherical polymer particles in the tissue. The particles include an interior region having relatively large pores and a first region substantially surrounding the interior having fewer relatively large pores than the interior region.