Abstract: Herein described is an apparatus for disgregating a biological tissue, such as an adipose tissue including stem and/or multipotent cells for use in regenerative medicine. The apparatus comprises a disposable device having a first duct for the passage of the biological tissue, the first duct having a first end and a second end. Each end of the first duct is configured for connection to an inlet/outlet opening of a respective handling and/or collecting device, particularly a pump device, such as a syringe. The disposable device further comprises an adjustment arrangement operable to cause a reduction of a passage section of the first duct.

Abstract: A detection and/or control device for a liquid-conducting appliance or system comprises:—a hydraulic body (2) defining a duct (3) for a flow of a liquid, the duct (3) having an inlet (4) and an outlet (5), and being made at least in part of an electrically insulating material;—a flow sensor located at least in part on the hydraulic body (2), which comprises:—an electromagnetic arrangement, configured for generating an electromagnetic field through said part of the duct (3), in a direction transverse to the flow of the liquid, —a detection arrangement, which comprises at least two electrode units (20) for detecting a potential difference induced by the flow of the liquid through the electromagnetic field, the at least two electrode units (20) being arranged for being in contact with the liquid in a respective working position.

Abstract: A co-continuous mouldable polymeric composite with PTC effect has a matrix that comprises at least two immiscible polymers (HDPE, POM), and an electrically conductive filler (CB) in the matrix. At least one of said immiscible polymers is high-density polyethylene (HDPE), and at least one other of said immiscible polymers is polyoxymethylene (POM).

Abstract: Component of tank of liquid additive of system for treating exhaust gases of internal combustion engine, has body positioned in fluid-tight way at opening of the tank and incorporates plurality of functional devices for managing liquid additive to be delivered to treatment system. Body of tank component is moulded using plastic material chemically resistant to liquid additive and is provided with at least one passageway for liquid additive. The plurality of functional devices comprises pump and pressure sensor having pressure-sensitive element. Passageway comprises delivery path for the liquid additive, which is defined at least in part in first wall of body of tank component and has inlet end configured for connection to delivery duct of the pump. Defined at outer side of first wall is at least one seat for positioning at least one part of pressure sensor.

Abstract: A mechanical-stress sensor comprises a piezoelectric transducer (10), which is able to generate an electrical signal representing a shear stress. The piezoelectric transducer (10) comprises: a layer of piezoelectric material (11), which extends in a longitudinal direction and has a polarization axis (A), which extends in a direction transverse to the longitudinal direction; and at least one first electrode (E1) and one second electrode (E2), each having a plurality of fingers (F1, F2), which extend at a first major face and a second major face, respectively, of the layer of piezoelectric material (11).

Abstract: An optical sensor device for detection of a characteristic of a liquid substance comprises a device body having an inner surface and an outer surface, one portion of the outer surface of the device body being designed to be in contact with the liquid substance, and the inner surface of the device body being designed to be isolated from the liquid substance. Associated to the device body is a detection arrangement, which comprises an emitter and a receiver of a given optical radiation. A first portion of the device body is made of a material designed for propagation of the given optical radiation, the emitter and the receiver being optically coupled to the inner surface of the device body in the first portion.

Abstract: A device (20) for creating cell-exclusion zones comprises a baseplate (21) having a first major face from which a plurality of exclusion reliefs (22) project, each exclusion relief (22) having at least one distal end (23) configured for contact with a bottom (11b) of a respective well (11) of a multi-well cell-culture plate (10). The baseplate (21) and the plurality of exclusion reliefs (22) are defined at least in part by an elastic or flexible material in such a way that at least the baseplate (21) is elastically deformable at least during removal thereof from a multi-well cell-culture plate (10), the elastic or flexible material preferably being an elastomer.

Abstract: A medical device for the separation of a concentrate enriched with cells from a biological fluid, in particular a concentrate of stromal or stem cells from medullar aspirate or venous blood, comprises: a treatment container for receiving and treating the biological fluid for the purposes of its separation into a number of fractions; a first collection container, for receiving a first fraction of the fluid, in particular a fraction poor in said cells; a second collection container, for receiving a second concentrated fraction of the fluid enriched with said cells; a deviator valve having a first way connected or prearranged for connection to the treatment container, a second way connected or prearranged for connection to the first collection container, and a third way connected or prearranged for connection to the second collection container; a first line for connection of the treatment container to the first way of the deviator valve, a second line for connection of the first collection container to the se

Abstract: An electrical heating device comprises: a first electrode layer (13), made of electrically conductive material; a second electrode layer (14), made of electrically conductive material; and a heating layer, made of a material having a PTC effect, wherein the first electrode layer (13) and the second electrode layer (14) face one another, with at least one part of the heating layer that is set between the first electrode layer (13) and the second electrode layer (14), in contact with them.

Abstract: A sensor device for a container of a liquid substance comprises a body with a housing portion having a closing structure, the body having an inner surface and an outer surface. The housing portion is pre-arranged for assembly on the container, in such a way that a portion of the outer surface of the body faces the inside of the container to be in contact with the liquid substance, and the inner surface of the body is isolated from the inside of the container. Associated to the body is a first arrangement for detection of the level of the substance. Associated to the body of the device is a second arrangement for detection of a characteristic of the liquid substance, which comprises an emitter and a receiver of a given optical radiation. A first portion of the body of the device is made of a material designed for propagation of the given optical radiation, the emitter and the receiver being optically coupled to the inner surface of the body at the first portion.

Abstract: An electrical heating device (10) comprises: a first electrode layer (13), made of electrically conductive material, a second electrode layer (14), made of electrically conductive material, a heating layer (15) made of at least one polymer-based material, the heating layer (15) having two opposite major sides, a casing (10a) made at least in part of polymer-based electrically insulating material. The first electrode layer (13) and the second electrode layer (14) are each associated at a respective major side of the heating layer (15), with at least one part (15?) of the heating layer (15) that is set between the first electrode layer (13) and the second electrode layer (14), in contact with them. The casing (10a) comprises at least one first casing layer (11) and one second casing layer (12), each facing a respective major side of the heating layer (15) and being made at least in part of a polymer-based material.

Abstract: A medical device for separating a fluid, in particular for separating platelet-rich plasma from whole blood, includes three containers and at least one corresponding connection line having an intermediate bifurcation. Provided on the connection line are valve means for enabling or preventing a flow of fluid. At least one container includes a hollow container body and a plunger associated in a movable way to the container body. The device also includes a filtering member on the connection line.

Abstract: A medical device for separating a fluid, in particular for separating platelet-rich plasma from whole blood, includes three containers and at least one corresponding connection line having an intermediate bifurcation. Provided on the connection line are valve means for enabling or preventing a flow of fluid. At least one container includes a hollow container body and a plunger associated in a movable way to the container body. A modular structure has modules connected to enable separation thereof. A first module includes at least the first container and a corresponding portion of the first connection line, and a second module, which has at least one between the second and third containers with a corresponding portion of the first connection line. Provided at least at the interface between two modules of the modular structure are releasable connectors, in particular hydraulic connectors having at least two parts that can be coupled together, each of which belongs to a corresponding module.

Abstract: A sensor device for a container of a liquid substance comprises a body with a housing portion having a closing structure, the body having an inner surface and an outer surface. The housing portion is pre-arranged for assembly on the container, in such a way that a portion of the outer surface of the body faces the inside of the container to be in contact with the liquid substance, and the inner surface of the body is isolated from the inside of the container. Associated to the body is a first arrangement for detection of the level of the substance. Associated to the body of the device is a second arrangement for detection of a characteristic of the liquid substance, which comprises an emitter and a receiver of a given optical radiation. A first portion of the body of the device is made of a material designed for propagation of the given optical radiation, the emitter and the receiver being optically coupled to the inner surface of the body at the first portion.

Abstract: Component of tank of liquid additive of system for treating exhaust gases of internal combustion engine, has body positioned in fluid-tight way at opening of the tank and incorporates plurality of functional devices for managing liquid additive to be delivered to treatment system. Body of tank component is moulded using plastic material chemically resistant to liquid additive and is provided with at least one passageway for liquid additive. The plurality of functional devices comprises pump and pressure sensor having pressure-sensitive element. Passageway comprises delivery path for the liquid additive, which is defined at least in part in first wall of body of tank component and has inlet end configured for connection to delivery duct of the pump. Defined at outer side of first wall is at least one seat for positioning at least one part of pressure sensor.

Abstract: Herein described is an apparatus for disgregating a biological tissue, such as an adipose tissue including stem and/or multipotent cells for use in regenerative medicine. The apparatus comprises a disposable device having a first duct for the passage of the biological tissue, the first duct having a first end and a second end. Each end of the first duct is configured for connection to an inlet/outlet opening of a respective handling and/or collecting device, particularly a pump device, such as a syringe. The disposable device further comprises an adjustment arrangement operable to cause a reduction of a passage section of the first duct.

Abstract: A heater device comprises a supporting body (5) and a plurality of heating elements in the supporting body (5). Each heating element includes a first electrode (14), a second electrode (15), and a material having a PTC effect (16) arranger at least in part between the two electrodes (14, 15). The first electrodes (14), respectively the second electrodes (15), are set at a distance apart in the supporting body (5), with the first electrodes (14) generally parallel to and facing the second electrodes (15). The first electrodes (14) are connected to a first common electrical conductor element (17), and the second electrodes (15) are connected to a second common electrical conductor element (18), and the material having a PTC effect (16) comprises a plastic-based or polymeric-based material moulded or overmoulded at least in part between facing surfaces of the first and second electrodes (14, 15).

Abstract: A medical device for the separation of a concentrate enriched with cells from a biological fluid, in particular a concentrate of stromal or stem cells from medullar aspirate or venous blood, comprises: a treatment container for receiving and treating the biological fluid for the purposes of its separation into a number of fractions; a first collection container, for receiving a first fraction of the fluid, in particular a fraction poor in said cells; a second collection container, for receiving a second concentrated fraction of the fluid enriched with said cells; a deviator valve having a first way connected or prearranged for connection to the treatment container, a second way connected or prearranged for connection to the first collection container, and a third way connected or prearranged for connection to the second collection container; a first line for connection of the treatment container to the first way of the deviator valve, a second line for connection of the first collection container to the se

Abstract: A medical device for separating a fluid, in particular for separating platelet-rich plasma from whole blood, includes three containers and at least one corresponding connection line having an intermediate bifurcation. Provided on the connection line are valve means for enabling or preventing a flow of fluid. At least one container includes a hollow container body and a plunger associated in a movable way to the container body. A modular structure has modules connected to enable separation thereof A first module includes at least the first container and a corresponding portion of the first connection line, and a second module, which has at least one between the second and third containers with a corresponding portion of the first connection line. Provided at least at the interface between two modules of the modular structure are releasable connectors, in particular hydraulic connectors having at least two parts that can be coupled together, each of which belongs to a corresponding module.

Abstract: A device for electrochemotherapy comprises an electric micro- or nano-capacitor which can be injected in the blood circulation of a human or animal body, including a pyroelectric or piezoelectric layer which can be excited from the outside of the human or animal body, for generating an electric field in the immediate vicinity of a tumor cell, together with the administration of a chemotherapeutic agent. The chemotherapeutic agent may be administered with independent means, but preferably is bound to the outer surface of the microcapacitor and is delivered because of the temperature increase which is generated at the time of the microcapacitor excitation.