Abstract: An anchoring device for anchoring a floating object to an anchor structure, including a first attachment suitable for being secured to the floating object; a second attachment for being secured to the anchor structure; a damping member for damping the relative motion between the attachments for securing the first attachment to the second attachment and including a slide chamber, a piston for sliding in the slide chamber according to a relative motion between the attachments and a damper for damping the sliding of the piston in the slide chamber; and a control unit including a measurement sensor for measuring the sliding of the piston; and a control board for varying the damping of the damper according to the sliding of the piston detected by the measurement sensor.

Abstract: Techniques regarding quantum computation of molecular excited states are provided. For example, one or more embodiments described herein can comprise a system, which can comprise a memory that can store computer executable components. The system can also comprise a processor, operably coupled to the memory, and that can execute the computer executable components stored in the memory. The computer executable components can comprise an initialization component that can categorize a plurality of excited operators from a mapped qubit Hamiltonian into sectors based on a commutation property of the plurality of excited operators with a symmetry from the mapped qubit Hamiltonian. The computer executable components can also comprise a matrix component that can generate an equation of motion matrix from an excited operator from the plurality of excited operators based on the sectors categorized by the initialization component.

Abstract: The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.

Abstract: An embodiment inertial measurement system includes: at least one motion sensor to output motion data with an output data rate (ODR) period; and a control unit coupled to the motion sensor to control operation thereof based on a power mode switching, according to which each ODR period includes: a first phase, in which the motion sensor is controlled in a condition of low power consumption; and a subsequent measurement phase, in which the motion sensor is controlled to perform measurements for generation of measurement data. The control unit adaptively adjusts the duration of the ODR period based on at least one check related to the measurement data generated during the measurement phase.

Abstract: The present invention concerns platelets transfected with exogenous genetic material and microparticles deriving from said transfected platelets having a high percentage of transfection and able to transport and to transfect acceptor cells with genetic material and then used for example in gene and cell therapy. The invention further concerns a method for the preparation of mature platelets transfected with exogenous genetic material and microparticles deriving from said transfected platelets and microparticles deriving from said transfected mature platelets which permits to obtain high percentages of transfection.

Abstract: A method for the computer-supported monitoring of the operation of a vehicle service includes providing in a test environment, a telematics control device of the vehicle type for which the vehicle service is intended to be monitored. The methods also includes simulating the vehicle using a first simulation unit generating test data and making the test data available to the telematics control device as status data on a vehicle bus. The method further includes simulating the data sink using a second simulation unit, wherein the simulated data sink is assigned to the simulated vehicle via a unique test vehicle identifier, at least in part by retrieving the status data stored for the simulated vehicle from the central computing system. The test data generated by the first simulation unit and the status data retrieved by the second simulation unit are evaluated at least in part using a comparison.

Abstract: This disclosure describes a fentanyl hapten, a fentanyl hapten-carrier conjugate, methods of making the fentanyl hapten and the fentanyl hapten-carrier conjugate, and methods of using the fentanyl hapten and the fentanyl hapten-carrier conjugate. The fentanyl hapten-carrier conjugate may be used, for example, as a prophylactic vaccine to counteract toxicity from exposure to fentanyl and its analogues. In some embodiments, the fentanyl hapten-carrier conjugate or a composition including the fentanyl hapten-carrier conjugate may be used in an anti-opioid vaccine.

Abstract: A hybrid classical-quantum computing device to execute a quantum circuit corresponding to a variational problem, is configured. The configuring further comprises causing the hybrid classical-quantum computing device to execute the quantum circuit by performing an adiabatic progression operation, wherein the adiabatic progression operation comprises increasing the difficulty of the variational problem from a simplified version of the problem to the variational problem.

Abstract: A multi-source illumination apparatus for illuminating a sample with charged particles, wherein beams, from a plurality of sources, are arranged such that a beam from at least one source intersects, at a plane of a condenser lens, with at least part of one other beam from a different one of the plurality of sources. The condenser lens is configured to separately collimate the received beams from each source. A manipulator array arrangement is configured to manipulate the collimated beams to generate one or more beams, in a single column, that include charged particles from the plurality of sources. The manipulator array arrangement includes a multi-beam generator configured to receive the plurality of substantially parallel substantially collimated beams generated by the deflector array, and generate a multibeam in dependence on the received plurality of substantially parallel substantially collimated beams, wherein the multi-beam includes a plurality of substantially collimated sub-beams.

Abstract: A flexible sensor is provided which has a flexible substrate of polymeric material, a bottom electrode layer arranged on the flexible substrate and configured to be a reference electrode, an active layer of piezoelectric material arranged on the bottom electrode layer, a top electrode layer arranged on the active layer and configured to be connected to a signal conductor, and a flexible coating layer of polymeric material that cooperates with the flexible substrate to encapsulate the bottom electrode layer, the active layer, and the top electrode layer. The flexible sensor has an additional layer of metal material arranged on the flexible coating layer and short-circuited to the bottom electrode layer, the additional layer and the bottom electrode layer acting as an electromagnetic shield for the flexible sensor.

Abstract: A rotor for an electric machine, in particular for a brushless DC motor, includes a hollow cylindrical main body that is rotationally fixed to a machine shaft. The main body includes a plurality of radial protrusions arranged over its casing surface in the circumferential direction and in the axial direction and offset relative to one another by a defined offset angle. Each radial protrusion is limited over an angular range, which is smaller than the offset angle. The hollow cylindrical main body is permanently connected, in particular adhered, to a hollow cylindrical body surrounding same in the circumferential direction by way of a joining process. A method for producing a rotor for an electric machine is also disclosed.

Abstract: A system may include a memory and a processor in communication with the memory. The processor may be configured to perform operations to accept ecosystem data and detect, analyze, and notify a user about a species in an environment. The system analysis and notification may include impact determination of the species on the environment and shall learn from the received and analyzed data, bringing intelligence to the system.

Abstract: The present invention relates to a device and a method for the analytical and/or sensory determination of the release of an active substance or several active substances from a release system. In particular, the present invention relates to a device and a method for determining the release of an active substance or active substances, in particular of an odiferous substance or flavoring or an odiferous substance or flavoring mixture, from a capsule or a precursor. Furthermore, the present invention relates to a device and a method for determining the properties of a release system, in particular of a capsule or a precursor. Ultimately, the present invention relates to the use of the device and method according to the invention for the analytical and/or sensory determination of the release of one or more active substances from a release system.

Abstract: Methods for processing HDPE recyclates including, but not limited to, polyethylene and polypropylene and compositions therefrom are provided. HDPE recyclate can be visbroken to improve processing characteristics and/or devolatilized to remove waste byproducts to produce processed HDPE recyclates. Processed HDPE recyclates are compounded with pre-consumer polyolefins to produce blend compositions having acceptable or even improved processing characteristics. Such pre-consumer polyolefins can also be visbroken to further tailor processing characteristics of such polymer blends. A combination of extruders and/or extruder zones can be used at the same or different locations for visbreaking and/or compounding of both HDPE recyclate and/or pre-consumer polyolefins.

Abstract: A scroll compressor is described. The scroll compressor comprises a case having a high-pressure side and a low-pressure side, a stationary scroll plate having a base plate with a first side having at least one projection, which forms a spiral wrap, and a second side having a first annular protrusion, a pilot plate for separating the high-pressure side of the case from the low-pressure side of the case and the pilot plate abutting the second side of the stationary scroll plate, wherein the pilot plate has a first side, wherein the first side faces the second side of the stationary scroll plate and wherein the first side has a second annular protrusion, and a seal, wherein the seal seals a radial gap between the first annular protrusion and the second annular protrusion.

Abstract: A method for manufacturing a spiral spring may include: (a) providing a blank with an Nb—Ti core; (b) beta-quenching the blank; (c) deforming the blank in several sequences; (d) winding to form the spiral spring; (e) final heat treatment on the spiral spring. The blank in (a) may include a layer of X including Cu, Sn, Fe, Pt, Pd, Rh, Al, Au, Ni, Ag, Co and Cr or an alloy of one of these elements around the Nb—Ti core. The method may include heat treating to partially transform the layer of X into a layer of X, Ti intermetals around the Nb—Ti core, and may be carried out between (b) and (c) or between two sequences of (c). The method may include removing the part of the layer of X, which may be carried out between (b) and (c), between two sequences of (c) or between (c) and (d).

Abstract: System, method, and circuitry for utilizing sequential input inertial sensor data to calculate recursive features for training a machine learning algorithm or for classifying the data as a known class. The recursive feature values of a current data sample are calculating based on comparisons between the current data sample value and previous recursive feature values. The recursive features include a recursive maximum, recursive minimum, recursive peak to peak, recursive average, recursive root mean square, and recursive variance.

Abstract: In an approach for explaining a theorem proving model, a processor predicts a truth value of a query through a pre-trained theorem proving model, based on the query and one or more facts and rules in a knowledge base. A processor ranks the one or more facts and rules according to contribution, calculated in a pre-defined scoring method, made to the predicted truth value of the query. A processor generates a proof of the predicted truth value, wherein the proof is one or more logical steps that demonstrate the predicted truth value in a natural language. A processor outputs the proof.

Abstract: An engine assembly is provided with a split-cycle internal combustion engine having a compression section and an expansion section and with a cooling circuit for circulating a heat-exchange fluid; said fluid has a boiling temperature such that at least a fraction of the fluid changes phase from liquid to vapour flowing through the expansion section of the engine, when the latter operates in steady conditions; the circuit comprises a turbine arranged downstream of the engine so as to receive vapour and produce mechanical energy from the expansion of the vapour.

Abstract: A spinal therapy apparatus includes one or more manipulating assemblies. In some examples a first manipulating member is arranged to engage a spine at a first vertebral area between a spinous process and a transverse process on a first side of a spine and a second manipulating member is arranged to engage the spine at a second vertebral area between a spinous process and a transverse process on the first side of the spine. The first and second manipulating members are coupled together at their proximal ends to permit the first and second manipulating members to be driven simultaneously and the coupling permits motion of the first and second manipulating members relative to one another in an axial direction. In other examples a drive system is adapted to drive first and second manipulating members simultaneously and independently. The disclosure also relates to a spinal therapy bed including such manipulating assemblies and methods of using and training spinal therapy devices.