Abstract: The present invention relates to a group of compounds with a structural nucleus derived from phenylacetamide, having the following formula (I): that can modulate the DREAM neuronal calcium sensor. Consequently, the present invention also relates to the use of these compounds for the treatment or prevention of disorders or diseases in which DREAM levels are above or below physiologically normal levels.

Abstract: The present invention provides uses of a glucokinase activator in combination with metformin. Uses include treating type 2 diabetes, lowering blood glucose, improving insulin sensitivity, enhancing phosphorylation of glucose, and improving the therapeutic effectiveness of metformin. The invention also provides pharmaceutical compositions that comprise a GK activator and metformin. The invention also provides a salt formed between metformin and a GK activator.

Abstract: The present invention provides uses of a glucokinase activator in combination with metformin. Uses include treating type 2 diabetes, lowering blood glucose, improving insulin sensitivity, enhancing phosphorylation of glucose, and improving the therapeutic effectiveness of metformin. The invention also provides pharmaceutical compositions that comprise a GK activator and metformin. The invention also provides a salt formed between metformin and a GK activator.

Abstract: The present invention relates to methods of treatment using [3-(4-{2-butyl-1-[4-(4-chloro-phenoxy)-phenyl]-1H-imidazol-4-yl}-phenoxy)-propyl]-diethyl amine (“COMPOUND I”) or a pharmaceutically acceptable salt thereof. In various embodiments, the methods of treatment include treatment of mild-to-moderate dementia of Alzheimer's type, diabetes, insomnia, and other indications. The present invention also relates to pharmaceutical compositions comprising COMPOUND I or a pharmaceutically acceptable salt thereof.

Abstract: The present invention relates to a new application of phosphodiesterase inhibitors for couple infertility treatment which forms an effective alternative to the invasive assisted reproductive techniques such as conjugal artificial insemination and which consists of the transvaginal administration of a phosphodiesterase inhibitor immediately before and/or after coitus. It also relates to dosage forms suitable for the intravaginal administration of phosphodiesterase inhibitors.

Abstract: A method for passivating a metal surface including, generating an atmospheric plasma beam by electrical discharge in a working gas, introducing an acid-containing passivating agent into the plasma beam, applying the plasma beam containing the passivating agent to the metal surface, and depositing a passivating salt on the metal surface by a reaction between the acid-containing passivating agent and the metal surface. This method simplifies the process for passivating a metal surface and renders it more effective.

Abstract: The present invention relates to methods of treatment using [3-(4-{2-butyl-1-[4-(4-chloro-phenoxy)-phenyl]-1H-imidazol-4-yl}-phenoxy)-propyl]-diethyl amine (“COMPOUND I”) or a pharmaceutically acceptable salt thereof. In various embodiments, the methods of treatment include treatment of mild-to-moderate dementia of Alzheimer's type, diabetes, insomnia, and other indications. The present invention also relates to pharmaceutical compositions comprising COMPOUND I or a pharmaceutically acceptable salt thereof.

Abstract: This invention relates to a powder mixture of absorbent fibers with oleophilic and hydrophobic properties, to a process for separating and/or collect oil, petroleum and all kinds of hydrocarbons, solvent or other selected liquid from oil, gasoline, diesel, solvents, antifreezes, acetone, ether, paraffins, waxes or oil paints, or combinations thereof, both in water and earthy soils involves the use of a powder mixture of absorbent fibers and recyclable adsorbents, the method for producing the mixture and their applications.

Abstract: Hanging shelf system comprising one or more vertical posts and one or more shelves fastened to said vertical posts, characterized in that said vertical posts are supporting cables which suspend from at least one support.

Abstract: The present invention provides methods for reducing loss of muscle strength, muscle mass, or Type I muscle fibers in an immobilized limb by administering (E)-[4-[3-(4-Fluorophenyl)-3-[4-[3-(morpholin-4-yl)propynyl]phenyl]allyloxy]-2-methyl-phenoxy]acetic acid or a pharmaceutically acceptable salt thereof.

Abstract: A portable information handling system keyboard rests on a support surface of a housing with securing actions taken from above the housing, such as by screws that insert through the keyboard and then into the housing. A lattice cover having key openings fits over the keyboard to align adapters of its bottom surface with posts extending from the support surface through openings formed in the keyboard. The adapters snap to the posts to couple the cover against the keyboard so that the cover bottom surface presses the keyboard against the information handling systems upper support surface.

Abstract: The present invention relates to a method for purifying a gas comprising: a) feeding the gas (1) to an absorber (5) and bringing into contact said gas (1) with a stream (3) (or alternatively (3?)) to obtain a liquid (4) and a purified gas stream (2); b) feeding the liquid (4) to a conditioning tank (9) and adding a mineral nutrient medium (6) and a suitable amount of base (7) to the liquid (4) to obtain a liquid effluent (8); c) feeding the liquid effluent (8) to an anaerobic bioreactor (14) to obtain a biomethane stream (11) and a liquid stream (12); d) feeding the liquid stream (12) to a degasser (20) to obtain a gas stream (18) and a stream (3?); and e) recirculating the stream (3?) by feeding it to the absorber (5).

Abstract: The present invention provides methods for treating muscle atrophy by administering a PPAR? agonist.

Abstract: A Home Subscriber Server for handling IP Multimedia Subsystem subscriptions comprises means for maintaining associations between public user identities and Service Profiles, where two or more public user identities can be associated with a common Service Profile, and means for identifying to a network node all public user identities that are associated with a common Service Profile.

Abstract: The present invention relates to a new application of phosphodiesterase inhibitors for couple infertility treatment which forms an effective alternative to the invasive assisted reproductive techniques such as conjugal artificial insemination and which consists of the transvaginal administration of a phosphodiesterase inhibitor immediately before and/or after coitus. It also relates to dosage forms suitable for the intravaginal administration of phosphodiesterase inhibitors.

Abstract: The present invention provides novel pyridyloxyacetyl tetrahydroisoquinoline compounds that inhibit NAMPT and may be useful in the treatment of cancer.

Abstract: A portable information handling system keyboard rests on a support surface of a housing with securing actions taken from above the housing, such as by screws that insert through the keyboard and then into the housing. A lattice cover having key openings fits over the keyboard to align adapters of its bottom surface with posts extending from the support surface through openings formed in the keyboard. The adapters snap to the posts to couple the cover against the keyboard so that the cover bottom surface presses the keyboard against the information handling systems upper support surface.

Abstract: A Home Subscriber Server for handling IP Multimedia Subsystem subscriptions comprises means for maintaining associations between public user identities and Service Profiles, where two or more public user identities can be associated with a common Service Profile, and means for identifying to a network node all public user identities that are associated with a common Service Profile.

Abstract: The present invention provides uses of a glucokinase activator in combination with metformin. Uses include treating type 2 diabetes, lowering blood glucose, improving insulin sensitivity, enhancing phosphorylation of glucose, and improving the therapeutic effectiveness of metformin. The invention also provides pharmaceutical compositions that comprise a GK activator and metformin. The invention also provides a salt formed between metformin and a GK activator.

Abstract: A method and apparatus capable of identifying a unique user across multiple devices in a computer network are provided. Device-specific and behavioral features associated with an event and a device are extracted. The device-specific features form a device signature associated the device. Hardware mobile device identifiers (IDs) are also associated with mobile application devices. Over a period of time, the behavioral features of such devices are monitored. Similarity scores between various devices are calculated based on the behavioral features and device types. The devices in the computer network are clustered and a device graph is generated representing the connections between the devices based on the similarity scores. A unique user ID associated with the multiple devices is generated from the device graph.