Patents by Inventor Maria Laura Avantaggiati

Maria Laura Avantaggiati has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREATING NON-ALCOHOLIC FATTY LIVER DISEASE AND INFLAMMATORY STEATOHEPATITIS WITH SLC25A1 INHIBITORS
    Publication number: 20220323389
    Abstract: Provided herein are methods for treating nonalcoholic fatty liver disease (NAFLD) or nonalcoholic steatohepatitis (NASH) in a subject, comprising administering to a subject having NAFLD or NASH an effective amount of a SLC25A1 inhibitor.
    Type: Application
    Filed: August 26, 2020
    Publication date: October 13, 2022
    Applicant: GEORGETOWN UNIVERSITY
    Inventor: Maria Laura AVANTAGGIATI
  • SMALL MOLECULE INHIBITORS OF SLC25A1
    Publication number: 20200246285
    Abstract: Methods of treating or preventing cancer, diabetes, and/or obesity in a subject are provided. The methods comprise administering to a subject a therapeutically effective amount of an SLC25A1 inhibitor as described herein. Also provided herein are pharmaceutical compositions comprising an SLC25A1 inhibitor and a chemotherapeutic agent. Further provided herein are methods of inhibiting SLC25A1 in a cell.
    Type: Application
    Filed: August 3, 2018
    Publication date: August 6, 2020
    Applicant: GEORGETOWN UNIVERSITY
    Inventors: Maria Laura Avantaggiati, Mikell Paige
  • BENZENETRICARBOXYLIC ACID AND METHODS OF USE
    Publication number: 20170087107
    Abstract: Methods of treating or preventing cancer and/or a neurodegenerative disorder in a subject are provided. The methods comprise administering to a subject a therapeutically effective amount of 1,2,3-benzenetricarboxylic acid or a hydrate or pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: December 12, 2016
    Publication date: March 30, 2017
    Applicant: GEORGETOWN UNIVERSITY
    Inventor: Maria Laura Avantaggiati
  • Benzenetricarboxylic acid and methods of use
    Patent number: 9545388
    Abstract: Methods of treating or preventing cancer and/or a neurodegenerative disorder in a subject are provided. The methods comprise administering to a subject a therapeutically effective amount of 1,2,3-benzenetricarboxylic acid or a hydrate or pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: October 22, 2013
    Date of Patent: January 17, 2017
    Assignee: GEORGETOWN UNIVERSITY
    Inventor: Maria Laura Avantaggiati
  • BENZENETRICARBOXYLIC ACID AND METHODS OF USE
    Publication number: 20150238449
    Abstract: Methods of treating or preventing cancer and/or a neurodegenerative disorder in a subject are provided. The methods comprise administering to a subject a therapeutically effective amount of 1,2,3-benzenetricarboxylic acid or a hydrate or pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: October 22, 2013
    Publication date: August 27, 2015
    Applicant: GEORGETOWN UNIVERSITY
    Inventor: Maria Laura Avantaggiati
  • COMPOSITIONS AND METHODS FOR DETECTING ACETYLATED SUMO PROTEINS
    Publication number: 20130288275
    Abstract: The invention is directed to methods of using antibodies or antibody fragments that specifically bind to an acetylation domain of a small ubiquitin-like modifier protein (SUMO protein) when the acetylation domain is at least partially acetylated. The invention is also directed towards antibodies or antibody fragments that specifically bind to an acetylation domain of a small ubiquitin-like modifier protein (SUMO protein) when the acetylation domain is at least partially acetylated.
    Type: Application
    Filed: May 6, 2011
    Publication date: October 31, 2013
    Applicant: Georgetown University
    Inventor: Maria Laura Avantaggiati