Patents by Inventor Maria Laura Gennaro

Maria Laura Gennaro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for immunodominant antigens of
    Patent number: 10053687
    Abstract: Contemplated compositions, devices, and methods are drawn to various antigens from the pathogen M. tuberculosis and their use in vaccines, therapeutic agents, and various diagnostic tests. In particularly preferred aspects, the antigens are immunodominant and have quantified and known relative reactivities with respect to sera of a population infected with the pathogen, and/or have a known association with a disease parameter.
    Type: Grant
    Filed: June 22, 2016
    Date of Patent: August 21, 2018
    Assignee: Immport Therapeutics, Inc.
    Inventors: Philip Felgner, Xiaowu Liang, Maria Laura Gennaro
  • Proteins expressed by and not by BCG and their use as diagnostic reagents and vaccines
    Patent number: 9782495
    Abstract: The present invention is directed to reagents useful for generating immune responses to Mycobacterium tuberculosis and for diagnosing infection and disease in a subject that has been exposed to M. tuberculosis.
    Type: Grant
    Filed: October 27, 2016
    Date of Patent: October 10, 2017
    Assignee: Rutgers, The State University of New Jersey
    Inventor: Maria Laura Gennaro
  • PROTEINS EXPRESSED BY MYCOBACTERIUM TUBERCULOSIS AND NOT BY BCG AND THEIR USE AS DIAGNOSTIC REAGENTS AND VACCINES
    Publication number: 20170043038
    Abstract: The present invention is directed to reagents useful for generating immune responses to Mycobacterium tuberculosis and for diagnosing infection and disease in a subject that has been exposed to M. tuberculosis.
    Type: Application
    Filed: October 27, 2016
    Publication date: February 16, 2017
    Applicant: Rutgers, The State University of New Jersey
    Inventor: Maria Laura Gennaro
  • Compositions And Methods For Immunodominant Antigens of Mycobacterium Tuberculosis
    Publication number: 20170023586
    Abstract: Contemplated compositions, devices, and methods are drawn to various antigens from the pathogen M. tuberculosis and their use in vaccines, therapeutic agents, and various diagnostic tests.
    Type: Application
    Filed: June 22, 2016
    Publication date: January 26, 2017
    Inventors: Philip Felgner, Xiaowu Liang, Maria Laura Gennaro
  • Compositions and methods for immunodominant antigens of
    Patent number: 9494586
    Abstract: Contemplated compositions, devices, and methods are drawn to various antigens from the pathogen M. tuberculosis and their use in vaccines, therapeutic agents, and various diagnostic tests. In particularly preferred aspects, the antigens are immunodominant and have quantified and known relative reactivities with respect to sera of a population infected with the pathogen, and/or have a known association with a disease parameter.
    Type: Grant
    Filed: October 12, 2014
    Date of Patent: November 15, 2016
    Assignee: Immport Theerapeutics, Inc.
    Inventors: Philip Felgner, Xiaowu Liang, Maria Laura Gennaro
  • PROTEINS EXPRESSED BY MYCOBACTERIUM TUBERCULOSIS AND NOT BY BCG AND THEIR USE AS DIAGNOSTIC REAGENTS AND VACCINES
    Publication number: 20160153986
    Abstract: The present invention is directed to reagents useful for generating immune responses to Mycobacterium tuberculosis and for diagnosing infection and disease in a subject that has been exposed to M. tuberculosis.
    Type: Application
    Filed: January 6, 2016
    Publication date: June 2, 2016
    Applicant: Rutgers, The State University of New Jersey
    Inventor: Maria Laura Gennaro
  • Compositions and methods for immunodominant antigens
    Patent number: 9297803
    Abstract: Contemplated compositions, devices, and methods comprise immunodominant antigens from selected human pathogens (Burkholderia pseudomallei, Borrelia burgdorferi, Brucella melitensis, Chlamydia muridarum, Coxiella burnetii, Francisella tularensis, human Herpes virus 1 and 2, Mycobacterium tuberculosis, Plasmodium falciparum, and Vaccinia virus) can be used as a vaccine, as diagnostic markers, and as therapeutic agents. In particularly preferred aspects, the antigens have quantified and known relative reactivities with respect to sera of a population infected with the pathogen, and have a known association with a disease parameter.
    Type: Grant
    Filed: November 1, 2007
    Date of Patent: March 29, 2016
    Assignees: Immport Therapeutics, Inc., Rutgers, The State University of New Jersey
    Inventors: Philip Felgner, David Huw Davies, Xiaowu Liang, Maria Laura Gennaro
  • Compositions And Methods For Immunodominant Antigens of Mycobacterium Tuberculosis
    Publication number: 20150168401
    Abstract: Contemplated compositions, devices, and methods are drawn to various antigens from the pathogen M. tuberculosis and their use in vaccines, therapeutic agents, and various diagnostic tests. In particularly preferred aspects, the antigens are immunodominant and have quantified and known relative reactivities with respect to sera of a population infected with the pathogen, and/or have a known association with a disease parameter.
    Type: Application
    Filed: October 12, 2014
    Publication date: June 18, 2015
    Inventors: Philip Felgner, Xiaowu Liang, Maria Laura Gennaro
  • Proteins expressed by and not by BCG and their use as diagnostic reagents and vaccines
    Patent number: 8992942
    Abstract: The present invention is directed to reagents useful for generating immune responses to Mycobacterium tuberculosis and for diagnosing infection and disease in a subject that has been exposed to M. tuberculosis.
    Type: Grant
    Filed: August 4, 2011
    Date of Patent: March 31, 2015
    Assignee: Rutgers, The State University of New Jersey
    Inventor: Maria Laura Gennaro
  • Proteins expressed by mycobacterium tuberculosis and not by BCG and their use as diagnostic reagents and vaccines
    Patent number: 8974800
    Abstract: The present invention is directed to reagents useful for generating immune responses to Mycobacterium tuberculosis and for diagnosing infection and disease in a subject that has been exposed to M. tuberculosis.
    Type: Grant
    Filed: May 14, 2013
    Date of Patent: March 10, 2015
    Assignee: Rutgers, The State University of New Jersey
    Inventor: Maria Laura Gennaro
  • Compositions and methods for immunodominant antigens of
    Patent number: 8883431
    Abstract: Contemplated compositions, devices, and methods are drawn to various antigens from the pathogen M. tuberculosis and their use in vaccines, therapeutic agents, and various diagnostic tests. In particularly preferred aspects, the antigens are immunodominant and have quantified and known relative reactivities with respect to sera of a population infected with the pathogen, and/or have a known association with a disease parameter.
    Type: Grant
    Filed: November 19, 2012
    Date of Patent: November 11, 2014
    Assignee: Immport Therapeutics, Inc.
    Inventors: Philip Felgner, Xiaowu Liang, Maria Laura Gennaro
  • Antibody profiles characteristic of tuberculosis state
    Patent number: 8722061
    Abstract: Serum antibody assays capable of distinguishing cases of inactive TB from cases of active TB include a combination of at least three M. tuberculosis protein antigens, at least one for which a positive response is consistent with inactive TB and antigens, and at least one for which a negative response is consistent with inactive TB.
    Type: Grant
    Filed: April 18, 2012
    Date of Patent: May 13, 2014
    Assignee: Rutgers, The State University of New Jersey
    Inventor: Maria Laura Gennaro
  • PROTEINS EXPRESSED BY MYCOBACTERIUM TUBERCULOSIS AND NOT BY BCG AND THEIR USE AS DIAGNOSTIC REAGENTS AND VACCINES
    Publication number: 20130251739
    Abstract: The present invention is directed to reagents useful for generating immune responses to Mycobacterium tuberculosis and for diagnosing infection and disease in a subject that has been exposed to M. tuberculosis.
    Type: Application
    Filed: May 14, 2013
    Publication date: September 26, 2013
    Applicant: University of Medicine & Dentistry of New Jersey
    Inventor: Maria Laura Gennaro
  • Compositions And Methods For Immunodominant Antigens of Mycobacterium Tuberculosis
    Publication number: 20130072398
    Abstract: Contemplated compositions, devices, and methods are drawn to various antigens from the pathogen M. tuberculosis and their use in vaccines, therapeutic agents, and various diagnostic tests. In particularly preferred aspects, the antigens are immunodominant and have quantified and known relative reactivities with respect to sera of a population infected with the pathogen, and/or have a known association with a disease parameter.
    Type: Application
    Filed: November 19, 2012
    Publication date: March 21, 2013
    Applicants: UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY, IMMPORT THERAPEUTICS, INC.
    Inventors: Philip Felgner, Xiaowu Liang, Maria Laura Gennaro
  • Compositions and methods for immunodominant antigens of
    Patent number: 8329418
    Abstract: Contemplated compositions, devices, and methods are drawn to various antigens from the pathogen M. tuberculosis and their use in vaccines, therapeutic agents, and various diagnostic tests. In particularly preferred aspects, the antigens are immunodominant and have quantified and known relative reactivities with respect to sera of a population infected with the pathogen, and/or have a known association with a disease parameter.
    Type: Grant
    Filed: February 14, 2012
    Date of Patent: December 11, 2012
    Assignee: ImmportTherapeutics, Inc.
    Inventors: Philip Felgner, Xiaowu Liang, Maria Laura Gennaro
  • Antibody Profiles Characteristic of Tuberculosis State
    Publication number: 20120202228
    Abstract: Serum antibody assays capable of distinguishing cases of inactive TB from cases of active TB include a combination at least three M. tuberculosis protein antigens, at least one for which a positive response is consistent with inactive TB and antigens, and at least one for which a negative response is consistent with inactive TB. Preferred assays further distinguish other TB classes. Also, antigen kits for performing such assays.
    Type: Application
    Filed: April 18, 2012
    Publication date: August 9, 2012
    Applicant: UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY
    Inventor: Maria Laura Gennaro
  • Compositions And Methods For Immunodominant Antigens of Mycobacterium Tuberculosis
    Publication number: 20120142555
    Abstract: Contemplated compositions, devices, and methods are drawn to various antigens from the pathogen M. tuberculosis and their use in vaccines, therapeutic agents, and various diagnostic tests. In particularly preferred aspects, the antigens are immunodominant and have quantified and known relative reactivities with respect to sera of a population infected with the pathogen, and/or have a known association with a disease parameter.
    Type: Application
    Filed: February 14, 2012
    Publication date: June 7, 2012
    Inventors: Philip Felgner, Xiaowu Liang, Maria Laura Gennaro
  • Proteins Expressed by Mycobacterium Tuberculosis and not by BCG and their Use as Diagnostic Reagents and Vaccines
    Publication number: 20120107247
    Abstract: The present invention is directed to reagents useful for generating immune responses to Mycobacterium tuberculosis and for diagnosing infection and disease in a subject that has been exposed to M. tuberculosis.
    Type: Application
    Filed: August 4, 2011
    Publication date: May 3, 2012
    Applicant: UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY
    Inventor: Maria Laura Gennaro
  • Compositions and methods for immunodominant antigens of
    Patent number: 8114614
    Abstract: Contemplated compositions, devices, and methods are drawn to various antigens from the pathogen M. tuberculosis and their use in vaccines, therapeutic agents, and various diagnostic tests. In particularly preferred aspects, the antigens are immunodominant and have quantified and known relative reactivities with respect to sera of a population infected with the pathogen, and/or have a known association with a disease parameter.
    Type: Grant
    Filed: March 31, 2011
    Date of Patent: February 14, 2012
    Inventors: Philip Felgner, Xiaowu Liang, Maria Laura Gennaro
  • Antibody Profiles Characteristic of Tuberculosis State
    Publication number: 20110306067
    Abstract: Serum antibody assays capable of distinguishing cases of inactive TB from cases of active TB include a combination at least three M. tuberculosis protein antigens, at least one for which a positive response is consistent with inactive TB and antigens, and at least one for which a negative response is consistent with inactive TB. Preferred assays further distinguish other TB classes. Also, antigen kits for performing such assays.
    Type: Application
    Filed: June 17, 2011
    Publication date: December 15, 2011
    Applicant: UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY
    Inventor: Maria Laura Gennaro