Abstract: This invention is related to an anti-tumoral composition for the treatment of neoplastic pathologies of malignant kind, and for the treatment of eg7 thymic lymphoma. Said composition comprises a TMEM176A/B inhibitor formulated in nanoparticles. This invention is also related to a method of treating neoplastic pathologies of malignant kind. Said method comprises the steps of administering to a subject a TMEM176A/B inhibitor formulated in nanoparticles.

Abstract: The present invention concerns the use of enzymes for removing soil from a surface during the rising of the surface, wherein the rinsing is following a washing cycle. The invention further concerns a rinse aid composition for rinsing the surface and a method for removing soil from the surface during a rinsing step.

Abstract: The present invention provides an in vitro method for detecting tumor growth and diagnosing or prognosticating the risk of metastasis in a human subject that has been diagnosed with uveal melanoma, wherein the method comprises using, as an indicator, the levels of PMEL/ME20-S/gp 100 positive exosomes, obtained from a biological sample isolated from the human subject selected from the list consisting of blood, or serum, of at least melanocyte protein PMEL/ME20-S/gp 100, and obtaining a result of the method by comparing the levels of at least said protein with a reference value or with the levels of a control, wherein an increase of melanocyte protein PMEL/ME20-S/gp 100 is indicative of a risk of the patient having or suffering from metastasis.

Abstract: The present invention concerns the use of enzymes for removing soil from a surface during the rising of the surface, wherein the rinsing is following a washing cycle. The invention further concerns a rinse aid composition for rinsing the surface and a method for removing soil from the surface during a rinsing step.

Abstract: A lace undergarment includes a waistband and a crotch element connected to the waistband. The waistband includes a pair of waistband elements connected together, each waistband element including a first end with a first width and a second end, positioned opposite the first end, the second end having a second width, larger than the first width. The first ends of each of the waistband elements are joined together to form a front of the waistband and the second ends of each waistband element is joined together to form a rear of the waistband. The crotch element includes a first end connected to the front of the waistband and a second end connected to the rear of the waistband.

Abstract: A lightweight brassiere is described that provides intended support to the user while increasing comfort by its structure and/or shape, and also by reduced weight. In particular a cup is made of a spacer fabric to provide the desired support at a minimum weight. Additional features include use of Ti-alloy materials in place of traditionally steel components, a narrower fabric channel for the underwire, and elimination of stitching by using sonic seal wherever possible.

Abstract: A brassiere garment having a pair of cup portions, each cup portion with an inner foam cup molded generally to the shape of the wearer's bust, and an outer fabric layer overlying the foam cup. Each foam cup has a first lower portion comprising a foam ply that is substantially inelastic in its lateral dimension, and a second upper portion that exhibits one or more of a lighter weight, lower density, greater elasticity and lesser thickness than the lower first portion. The lower first portion and upper second portion join with one another along a line generally traversing the foam cup from a lower and inward side of the foam cup and extending upward and laterally outward in direction. In certain embodiments, the line along which the lower first portion and upper second portion are joined with one another generally extends to or through the apex of the foam cup.

Abstract: Artificial niches which provide growth, differentiation, and/or anti-aging environments for stem cells and progenitor cells are described.

Abstract: The invention provides a novel method of vaccination of an animal of the felidae family against feline leukemia. The FeLV recombinant vaccine based on viral vector with the aid of a liquid jet needle-free injector can result in distribution of the vaccine essentially in the dermis and the hypodermis of the animal.