Patents by Inventor Maria Prat

Maria Prat has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240084390
    Abstract: The present invention refers to an in vitro method for the prognosis of patients suffering from HER2+ breast cancer and/or for the prediction of response to anti-HER2 therapies in patients suffering from HER2+ breast cancer.
    Type: Application
    Filed: July 26, 2021
    Publication date: March 14, 2024
    Inventors: Aleix Prat Aparicio, Laia Peré Brunet, Pierfranco Conte, Maria Vittoria Dieci, Valentina Guarneri
  • Publication number: 20220143212
    Abstract: Biomimetic magnetic nanoparticles comprising MamC. The present invention provides superparamagnetic biomimetic nanoparticles comprising magnetite, which can be produced using a scalable process. In addition, these nanoparticles exhibit promising properties, since, if functionalized, they can be converted into drug carriers or contrast agents for obtaining clinical images. They can also be used in clinical setting to purge bone marrow, as molecule separators, and/or for environmental applications as biosensors. These nanoparticles, coupled to a drug, can be encapsulated in liposomes, thereby obtaining magnetoliposomes, which can be functionalized for use in the targeted delivery/release of drugs.
    Type: Application
    Filed: November 4, 2019
    Publication date: May 12, 2022
    Inventors: Concepción JIMÉNEZ LÓPEZ, Carmen VALVERDE TERCEDOR, Ana PEIGNEUX NAVARRO, Ylenia María JABALERA RUZ, María PRAT, Francesca OLTOLINA
  • Patent number: 10588895
    Abstract: Provided is a method for treating chronic obstructive pulmonary disease or chronic bronchitis, or inhibiting bronchospasm, which method comprises use of a powder inhaler to administer to a human patient in need of such treatment an effective amount of a powder inhalant, wherein the powder inhalant comprises 3(R)-(2-hydroxy-2,2-dithien-2-ylacetoxy)-1-(3-phenoxypropyl)-1-azoniabicyclo[2.2.2]octane bromide.
    Type: Grant
    Filed: July 25, 2018
    Date of Patent: March 17, 2020
    Assignee: ALMIRALL, S.A.
    Inventors: Maria Dolors Fernandez Forner, Maria Prat Quinones, Maria Antonia Buil Albero
  • Publication number: 20190183867
    Abstract: Provided is a method for treating chronic obstructive pulmonary disease or chronic bronchitis, or inhibiting bronchospasm, which method comprises use of a powder inhaler to administer to a human patient in need of such treatment an effective amount of a powder inhalant, wherein the powder inhalant comprises 3(R)-(2-hydroxy-2,2-dithien-2-ylacetoxy)-1-(3-phenoxypropy1)-1-azoniabicyclo[2.2.2]octane bromide.
    Type: Application
    Filed: July 25, 2018
    Publication date: June 20, 2019
    Inventors: Maria Dolors FERNANDEZ FORNER, Maria PRAT QUINONES, Maria Antonia BUIL ALBERO
  • Patent number: 10300072
    Abstract: The present invention relates to novel compounds having ?2 adrenergic agonist and M3 muscarinic antagonist dual activity, to pharmaceutical compositions containing them, to the process for their preparation and to their use in respiratory therapies.
    Type: Grant
    Filed: August 4, 2017
    Date of Patent: May 28, 2019
    Assignee: Almirall, S.A.
    Inventors: Jose Aiguade Bosch, Silvia Gual Roig, Maria Prat Quinones, Carlos Puig Duran
  • Patent number: 10034867
    Abstract: Provided is a powder inhaler comprising a powder inhalant comprising 3(R)-(2-hydroxy-2,2-dithien-2-ylacetoxy)-1-(3-phenoxypropyl)-1-azoniabicyclo[2.2.2]octane wherein an anion X? is associated with the positive charge of the nitrogen atom and wherein X? is a pharmaceutically acceptable anion of a mono- or polyvalent acid.
    Type: Grant
    Filed: May 19, 2017
    Date of Patent: July 31, 2018
    Assignee: ALMIRALL, S.A.
    Inventors: Maria Dolors Fernandez Forner, Maria Prat Quinones, Maria Antonia Buil Albero
  • Patent number: 10005771
    Abstract: The present invention relates to novel compounds having ?2 adrenergic agonist and M3 muscarinic antagonist dual activity, to pharmaceutical compositions containing them, to the process for their preparation and to their use in respiratory therapies.
    Type: Grant
    Filed: September 25, 2015
    Date of Patent: June 26, 2018
    Assignee: Almirall, S.A.
    Inventors: Carlos Puig Duran, Jose Aiguade Bosch, Silvia Gual Roig, Maria Prat Quiñones
  • Publication number: 20180015097
    Abstract: The present invention relates to novel compounds having ?2 adrenergic agonist and M3 muscarinic antagonist dual activity, to pharmaceutical compositions containing them, to the process for their preparation and to their use in respiratory therapies.
    Type: Application
    Filed: August 4, 2017
    Publication date: January 18, 2018
    Inventors: Jose AIGUADE BOSCH, Silvia Gual Roig, Maria Prat Quinones, Carlos Puig Duran
  • Publication number: 20170319557
    Abstract: Provided is a powder inhaler comprising a powder inhalant comprising 3(R)-(2-hydroxy-2,2-dithien-2-ylacetoxy)-1-(3-phenoxypropyl)-1-azoniabicyclo[2.2.
    Type: Application
    Filed: May 19, 2017
    Publication date: November 9, 2017
    Inventors: Maria Dolors FERNANDEZ FORNER, Maria PRAT QUINONES, Maria Antonia BUIL ALBERO
  • Publication number: 20170275277
    Abstract: The present invention relates to novel compounds having ?2 adrenergic agonist and M3 muscarinic antagonist dual activity, to pharmaceutical compositions containing them, to the process for their preparation and to their use in respiratory therapies.
    Type: Application
    Filed: September 24, 2015
    Publication date: September 28, 2017
    Inventors: Carlos PUIG DURAN, Jose AIGUADE BOSCH, Silvia GUAL ROIG, Maria PRAT QUIÑONES
  • Patent number: 9757383
    Abstract: The present invention relates to novel compounds having ?2 adrenergic agonist and M3 muscarinic antagonist dual activity, to pharmaceutical compositions containing them, to the process for their preparation and to their use in respiratory therapies.
    Type: Grant
    Filed: December 2, 2015
    Date of Patent: September 12, 2017
    Assignee: Almirall, S.A.
    Inventors: Jose Aiguade Bosch, Silvia Gual Roig, Maria Prat Quinones, Carlos Puig Duran
  • Patent number: 9687478
    Abstract: Provided is an aerosol container comprising a powder inhalant comprising 3(R)-(2-hydroxy-2,2-dithien-2-ylacetoxy)-1-(3-phenoxypropyl)-1-azoniabicyclo[2.2.2]octane wherein an anion X? is associated with the positive charge of the nitrogen atom and wherein X? is a pharmaceutically acceptable anion of a mono- or polyvalent acid.
    Type: Grant
    Filed: April 9, 2016
    Date of Patent: June 27, 2017
    Assignee: ALMIRALL, S.A.
    Inventors: Maria Dolors Fernandez Forner, Maria Prat Quinones, Maria Antonia Buil Albero
  • Patent number: 9643961
    Abstract: The present invention relates to novel compounds having ?2 adrenergic agonist and M3 muscarinic antagonist dual activity, to pharmaceutical compositions containing them, to the process for their preparation and to their use in respiratory therapies.
    Type: Grant
    Filed: March 14, 2016
    Date of Patent: May 9, 2017
    Assignee: Almirall, S.A.
    Inventors: Maria Prat Quinones, Silvia Fonquerna Pou, Carlos Puig Duran, Wenceslao Lumeras Amador, Jose Aiguade Bosch, Juan Francisco Caturla Javaloyes
  • Patent number: 9579316
    Abstract: The present invention is directed to crystalline addition salts of (i) 8-hydroxyquinolin-2(1H)-one derivatives and (ii) a dicarboxylic acid or a sulfimide, or a pharmaceutically acceptable solvates thereof.
    Type: Grant
    Filed: July 24, 2014
    Date of Patent: February 28, 2017
    Assignee: Almirall, S.A.
    Inventors: Montserrat Julia Jane, Francesc Carrera Carrera, Maria Prat Quiñones, Carlos Puig Duran, Francesca Pajuelo Lorenzo, Juan Antonio Perez Andres
  • Patent number: 9562039
    Abstract: The present invention is directed to crystalline addition salts of (i) 8-hydroxyquinolin-2(1H)-one derivatives and (ii) a hydroxycarboxylic acid, a sulfonic acid or a sulfimide, or a pharmaceutically acceptable solvates thereof.
    Type: Grant
    Filed: February 27, 2014
    Date of Patent: February 7, 2017
    Assignee: Almirall, S.A.
    Inventors: Montserrat Julia Jane, Francesc Carrera Carrera, Maria Prat Quiñones, Carlos Puig Duran, Francesca Pajuelo Lorenzo, Juan Antonio Perez Andres
  • Patent number: 9549934
    Abstract: The present invention relates to novel compounds having ?2 adrenergic agonist and M3 muscarinic antagonist dual activity, to pharmaceutical compositions containing them, to the process for their preparation and to their use in respiratory therapies.
    Type: Grant
    Filed: December 2, 2015
    Date of Patent: January 24, 2017
    Assignee: Almirall, S.A.
    Inventors: Jose Aiguade Bosch, Silvia Gual Roig, Maria Prat Quinones, Carlos Puig Duran
  • Publication number: 20160296503
    Abstract: Provided is an aerosol container comprising a powder inhalant comprising 3(R)-(2-hydroxy-2,2-dithien-2-ylacetoxy)-1-(3-phenoxypropyl)-1-azoniabicyclo[2.2.2]octane wherein an anion X? is associated with the positive charge of the nitrogen atom and wherein X? is a pharmaceutically acceptable anion of a mono- or polyvalent acid.
    Type: Application
    Filed: April 9, 2016
    Publication date: October 13, 2016
    Inventors: Maria Dolors FERNANDEZ FORNER, Maria PRAT QUINONES, Maria Antonia BUIL ALBERO
  • Publication number: 20160264557
    Abstract: The present invention relates to novel compounds having ?2 adrenergic agonist and M3 muscarinic antagonist dual activity, to pharmaceutical compositions containing them, to the process for their preparation and to their use in respiratory therapies.
    Type: Application
    Filed: March 14, 2016
    Publication date: September 15, 2016
    Inventors: Maria PRAT QUINONES, Silvia FONQUERNA POU, Carlos PUIG DURAN, Wenceslao LUMERAS AMADOR, Jose AIGUADE BOSCH, Juan Francisco CATURLA JAVALOYES
  • Publication number: 20160200718
    Abstract: The present invention relates to novel compounds having ?2 adrenergic agonist and M3 muscarinic antagonist dual activity, to pharmaceutical compositions containing them, to the process for their preparation and to their use in respiratory therapies.
    Type: Application
    Filed: December 2, 2015
    Publication date: July 14, 2016
    Inventors: Jose AIGUADE BOSCH, Silvia GUAL ROIG, Maria PRAT QUINONES, Carlos PUIG DURAN
  • Patent number: RE46417
    Abstract: A compound according to formula (I) wherein: © is a phenyl ring, a C4 to C9 heteroaromatic compound containing one or more heteroatoms, or a naphthalenyl, 5,6,7,8-tetrahydronaphthalenyl or biphenyl group; which shows high affinity for muscarinic M3 receptors (Hm3).
    Type: Grant
    Filed: February 9, 2016
    Date of Patent: May 30, 2017
    Assignee: Almirall, S.A.
    Inventors: Dolors Fernandez Forner, Maria Prat Quiñones, Maria Antonia Buil Albero