Patents by Inventor Maria S. Nightingale

Maria S. Nightingale has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mammalian muscle NAD: arginine ADP-ribosyltransferase
    Patent number: 5834310
    Abstract: This invention relates to the identification and molecular characterization of NAD:arginine ADP-ribosyltransferases. Sequences from the rabbit skeletal muscle NAD:arginine ADP-ribosyltransferase and the human NAD:arginine ADP-ribosyltransferase are provided herein. Recombinant protein is expressed from a recombinant gene vector containing at least 15 continuous bases of genes encoding these sequences.
    Type: Grant
    Filed: July 18, 1997
    Date of Patent: November 10, 1998
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Joel Moss, Ian Okazaki, Anna Zolkiewska, Maria S. Nightingale
  • Clones encoding mammalian ADP-ribosylarginine hydrolases
    Patent number: 5716816
    Abstract: The present invention relates to the production of mammalian ADP-ribosylarginine hydrolases. These enzymes can be manufactured using recombinant DNA technology and are useful in regulation of proteins involved in key metabolic pathways.
    Type: Grant
    Filed: January 14, 1994
    Date of Patent: February 10, 1998
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Joel Moss, Sally J. Stanley, Maria S. Nightingale, Lucia Monaco, James J. Murtagh, Jr., Tatsuyuki Takada
  • Mammalian guanine nucleotide binding protein with an ADP-ribosylation factor domain
    Patent number: 5514600
    Abstract: The invention provides a method for detecting the presence of ARD 1 protein in a sample. The method includes the steps of providing labeled or immobilized anti-ARD 1 antibody in a reaction zone, introducing sample into the reaction zone such that ARD 1 protein in the sample, if present, will react with said antibody to form an immunological complex, and detecting the formation of said immunological complex. Cells, nucleotide and amino acid sequences and vectors associated with ARD 1 are also described.
    Type: Grant
    Filed: September 27, 1994
    Date of Patent: May 7, 1996
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Joel Moss, Koichi Mishima, Maria S. Nightingale, Mikako Tsuchiya
  • Mammalian guanine nucleotide binding protein with an ADP-rybosylation factor domain
    Patent number: 5386021
    Abstract: The invention provides a method for detecting the presence of ARD 1 protein in a sample. The method includes the steps of providing labeled or immobilized anti-ARD 1 antibody in a reaction zone, introducing sample into the reaction zone such that ARD 1 protein in the sample, if present, will react with said antibody to form an immunological complex, and detecting the formation of said immunological complex. Cells, nucleotide and amino acid sequences and vectors associated with ARD 1 are also described.
    Type: Grant
    Filed: April 19, 1993
    Date of Patent: January 31, 1995
    Assignee: The United States of America, as represented by the Department of Health & Human Services
    Inventors: Joel Moss, Koichi Mishima, Maria S. Nightingale, Mikako Tsuchiya