Patents by Inventor Mariya Ivanova Doneva
Mariya Ivanova Doneva has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11953571Abstract: A medical system including a memory storing machine executable instructions is disclosed. The medical system also includes a computational system. The execution of the machine executable instructions causes the computational system to receive k-space data descriptive of a region of interest of a subject. The k-space data are acquired using a magnetic resonance fingerprinting pulse sequence configured for encoding chemical shifts. The execution of the machine executable instructions also causes the computational system to receive fat peak weights descriptive of a magnetic resonance fat spectrum. The fat peak weights are matched to a pulse train of the magnetic resonance fingerprinting pulse sequence. The execution of the machine executable instructions also causes the computational system to reconstruct a quantitative magnetic resonance image from the k-space data and the fat peak weights.Type: GrantFiled: March 7, 2022Date of Patent: April 9, 2024Assignee: Koninklijke Philips N.V.Inventors: Dominick Johannes Weidlich, Stefan Ruschke, Elizabeth Huaroc, Mariya Ivanova Doneva, Dimitrios Karampinos
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Publication number: 20230288514Abstract: Disclosed herein is a medical system (100, 300) comprising a memory (110) storing machine executable instructions (120) and an MRF scoring module (122). The MRF scoring module is configured for outputting an MRF quality score (126) in response to receiving MRF data (124) as input. The medical system further comprises a computational system (106) configured for controlling the medical system, wherein execution of the machine executable instructions causes the computational system to: receive (200) the MRF data; receive (202) the MRF quality score in response to inputting the MRF data into an MRF scoring module; append (206) the MRF quality score to the MRF data if the MRF quality score is within a predetermined range (128); and provide (208) a signal (132) if the MRF quality score is outside of the predetermined range.Type: ApplicationFiled: July 1, 2021Publication date: September 14, 2023Inventors: Thomas Erik Amthor, Mariya Ivanova Doneva, Peter Koken, Kay Nehrke
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Patent number: 11579230Abstract: The invention provides for a magnetic resonance imaging system (100) for acquiring magnetic resonance data (142) from a subject (118) within a measurement zone (108). The magnetic resonance imaging system (100) comprises: a processor (130) for controlling the magnetic resonance imaging system (100) and a memory (136) storing machine executable instructions (150, 152, 154), pulse sequence commands (140) and a dictionary (144). The pulse sequence commands (140) are configured for controlling the magnetic resonance imaging system (100) to acquire the magnetic resonance data (142) of multiple steady state free precession (SSFP) states per repetition time. The pulse sequence commands (140) are further configured for controlling the magnetic resonance imaging system (100) to acquire the magnetic resonance data (142) of the multiple steady state free precession (SSFP) states according to a magnetic resonance fingerprinting protocol. The dictionary (144) comprises a plurality of tissue parameter sets.Type: GrantFiled: December 6, 2017Date of Patent: February 14, 2023Assignee: Koninklijke Philips N.V.Inventors: Karsten Sommer, Mariya Ivanova Doneva, Thomas Erik Amthor, Peter Koken, Jan Jakob Meineke
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Publication number: 20220283252Abstract: Disclosed herein is a medical system comprising a memory storing machine executable instructions. The medical system further comprises a computational system. The execution of the machine executable instructions causes the computational system to: receive k-space data descriptive of a region of interest of a subject, wherein the k-space data is acquired using a magnetic resonance fingerprinting pulse sequence configured for encoding chemical shifts; receive fat peak weights descriptive of a magnetic resonance fat spectrum, wherein the fat peak weights are matched to a pulse train of the magnetic resonance fingerprinting pulse sequence; and reconstruct a quantitative magnetic resonance image from the k-space data and the fat peak weighs.Type: ApplicationFiled: March 7, 2022Publication date: September 8, 2022Inventors: DOMINICK JOHANNES WEIDLICH, STEFAN RUSCHKE, ELIZABETH HUAROC, MARIYA IVANOVA DONEVA, DIMITRIOS KARAMPINOS
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Patent number: 11435422Abstract: The invention provides for a medical imaging system comprising: a memory for storing machine executable instructions; a processor for controlling the medical instrument. Execution of the machine executable instructions causes the processor to: receive MRF magnetic resonance data acquired according to an MRF magnetic resonance imaging protocol of a region of interest; reconstruct an MRF vector for each voxel of a set of voxels descriptive of the region of interest using the MRF magnetic resonance data according to the MRF magnetic resonance imaging protocol; calculate a preprocessed MRF vector (126) for each of the set of voxels by applying a predetermined preprocessing routine to the MRF vector for each voxel, wherein the predetermined preprocessing routine comprises normalizing the preprocessed MRF vector for each voxel; calculate an outlier map for the set of voxels by assigning an outlier score to the preprocessed MRF vector using a machine learning algorithm.Type: GrantFiled: September 22, 2020Date of Patent: September 6, 2022Assignee: Koninklijke Philips N.V.Inventors: Thomas Erik Amthor, Mariya Ivanova Doneva, Jan Jakob Meineke
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Publication number: 20220252688Abstract: It is an object of present invention to provide for a faster method of multi-component analysis. This object is achieved by a method for multi-component analysis on MRI measurement data, wherein a component is defined by one or more tissue component parameters among which preferably one is a T2 or T1 value.Type: ApplicationFiled: April 14, 2020Publication date: August 11, 2022Inventors: MARIYA IVANOVA DONEVA, MARTIJN ARIE NAGTEGAAL
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Patent number: 11269037Abstract: The invention relates to a method of MR imaging of an object (10) placed in an examination volume of a MR device (1). It is an object of the invention to enable MR imaging using a radial (or spiral) acquisition scheme with a reduced level of motion artefacts. The method of the invention comprises the following sequence of steps: —detecting a momentary motion—induced displacement (?) of the object (10); —attributing the detected displacement (A) to a motion state (M1-M5), each motion state (M1-M5) corresponding to one of a plurality of contiguous ranges of displacements (?); —determining angular coordinates of a radial or spiral k-space profile by incrementing the angular coordinates individually for each motion state (M1-M5) starting from initial angular coordinates; —acquiring the k-space profile; —repeating steps a-d a number of times; and —reconstructing an MR image from at least the k-space profiles attributed to one of the motion states (M1-M5).Type: GrantFiled: October 5, 2018Date of Patent: March 8, 2022Assignee: Koninklijke Philips N.V.Inventors: Mariya Ivanova Doneva, Jan Hendrik Wulbern, Gabriele Marianne Beck
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Patent number: 11241162Abstract: A method of operating a magnetic resonance imaging system (10) with regard to acquiring multiple-phase dynamic contrast-enhanced magnetic resonance images, the method comprising steps of acquiring (48) a first set of magnetic resonance image data (xpre) prior to administering a contrast agent to the subject of interest (20), by employing a water/fat magnetic resonance signal separation technique, determining (52) a first image of the spatial distribution of fat (Ipre) of at least the portion of the subject of interest (20), acquiring (50) at least a second set of magnetic resonance image data (x2) of at least the portion of the subject of interest (20) after administering the contrast agent to the subject of interest (20), by employing a water/fat magnetic resonance signal separation technique, determining (54) at least a second image of the spatial distribution of fat (I2ph) of at least the portion of the subject of interest (20), applying (56) an image registration method to the second image of the spatialType: GrantFiled: March 31, 2015Date of Patent: February 8, 2022Assignees: Koninklijke Philips N.V., Board of Regents of the University of Texas SystemsInventors: Nadine Gdaniec, Peter Boernert, Mariya Ivanova Doneva, Ivan Pedrosa
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Patent number: 11112478Abstract: The invention provides for a magnetic resonance imaging system (100) for acquiring MRF magnetic resonance data (144) from a subject (118) within a region of interest (109). The magnetic resonance imaging system comprises a processor (130) for controlling the magnetic resonance imaging system and a memory (134) for storing machine executable instructions (140) and MRF pulse sequence commands (142). The MRF pulse sequence commands are configured for controlling the magnetic resonance imaging system to acquire the MRF magnetic resonance data according to a magnetic resonance fingerprinting protocol.Type: GrantFiled: March 30, 2018Date of Patent: September 7, 2021Assignee: Koninklijke Philips N.V.Inventors: Peter Boernert, Thomas Erik Amthor, Mariya Ivanova Doneva, Fabian Wenzel
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Patent number: 11092659Abstract: A magnetic resonance imaging (MRI) system (100) includes a memory (134) for storing machine executable instructions (140) and magnetic resonance fingerprinting (MRF) pulse sequence commands (142) which cause the MRI system to acquire MRF magnetic resonance data (144) according to an MRF protocol. The pulse sequence commands are configured for acquiring the MRF magnetic resonance data in two-dimensional slices (410, 412, 414, 416, 418, 420), having a slice selection direction. A train of pulse sequence repetitions includes a sampling event where the MRF data is repeatedly sampled.Type: GrantFiled: March 30, 2018Date of Patent: August 17, 2021Assignee: Koninklijke Philips N.V.Inventors: Thomas Erik Amthor, Mariya Ivanova Doneva, Karsten Sommer, Peter Koken
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Patent number: 11085985Abstract: A magnetic resonance imaging (MRI) system includes a memory for storing machine executable instructions and MRF pulse sequence commands. The MRF pulse sequence commands are configured for controlling the MRI system to acquire MRF magnetic resonance data according to a magnetic resonance fingerprinting protocol. The memory further includes a Fourier transformed magnetic resonance finger printing dictionary. The finger printing dictionary includes entries for at least one intrinsic property.Type: GrantFiled: July 3, 2018Date of Patent: August 10, 2021Assignee: Koninklijke Philips N.V.Inventors: Karsten Sommer, Thomas Erik Amthor, Jan Jakob Meineke, Peter Koken, Mariya Ivanova Doneva
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Publication number: 20210109180Abstract: The invention provides for a magnetic resonance imaging system (100) for acquiring MRF magnetic resonance data (144) from a subject (118) within a region of interest (109). The magnetic resonance imaging system comprises a processor (130) for controlling the magnetic resonance imaging system and a memory (134) for storing machine executable instructions (140) and MRF pulse sequence commands (142). The MRF pulse sequence commands are configured for controlling the magnetic resonance imaging system to acquire the MRF magnetic resonance data according to a magnetic resonance fingerprinting protocol.Type: ApplicationFiled: March 30, 2018Publication date: April 15, 2021Inventors: PETER BOERNERT, THOMAS ERIK AMTHOR, MARIYA IVANOVA DONEVA, FABIAN WENZEL
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Publication number: 20210003650Abstract: The invention provides for a medical imaging system comprising: a memory for storing machine executable instructions; a processor for controlling the medical instrument. Execution of the machine executable instructions causes the processor to: receive MRF magnetic resonance data acquired according to an MRF magnetic resonance imaging protocol of a region of interest; reconstruct an MRF vector for each voxel of a set of voxels descriptive of the region of interest using the MRF magnetic resonance data according to the MRF magnetic resonance imaging protocol; calculate a preprocessed MRF vector (126) for each of the set of voxels by applying a predetermined preprocessing routine to the MRF vector for each voxel, wherein the predetermined preprocessing routine comprises normalizing the preprocessed MRF vector for each voxel; calculate an outlier map for the set of voxels by assigning an outlier score to the preprocessed MRF vector using a machine learning algorithm.Type: ApplicationFiled: September 22, 2020Publication date: January 7, 2021Inventors: Thomas Erik AMTHOR, Mariya Ivanova DONEVA, Jan Jakob MEINEKE
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Patent number: 10816625Abstract: The invention provides for a magnetic resonance imaging system (100) for acquiring magnetic resonance data (142) from a subject (118) within an imaging zone (108). The magnetic resonance imaging system comprises a memory (134, 136) for storing machine executable instructions (160), and pulse sequence commands (140, 400, 502, 600, 700), wherein the pulse sequence commands are configured to cause the magnetic imaging resonance system to acquire the magnetic resonance data according to a magnetic resonance fingerprinting technique. The pulse sequence commands are further configured to control the magnetic resonance imaging system to perform spatial encoding using a zero echo time magnetic resonance imaging protocol.Type: GrantFiled: April 26, 2017Date of Patent: October 27, 2020Assignee: Koninklijke Philips N.V.Inventors: Peter Bornert, Kay Nehrke, Mariya Ivanova Doneva, Thomas Erik Amthor, Peter Koken, George Randall Duensing
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Patent number: 10788556Abstract: A magnetic resonance imaging system (100) acquires magnetic resonance data (142) from a subject (118) within a measurement zone (108). Pulse sequence commands (140) control the magnetic resonance imaging system to acquire the magnetic resonance data according to a magnetic resonance fingerprinting protocol. The pulse sequence commands are configured for controlling the magnetic resonance imaging system to repeatedly generate an RF pulse train (300) and acquire the magnetic resonance data as multiple k-space traces. The machine executable instructions causes the processor to: sequentially acquire (200) the multiple k-space traces of magnetic resonance data by controlling the magnetic resonance imaging system with pulse sequence commands and calculate (202) the abundance of each of a set of predetermined substances for k-space traces that are acquired after a predetermined number of k-space traces of the multiple k-space traces has been acquired and the acquired magnetization has reached a steady state.Type: GrantFiled: February 6, 2017Date of Patent: September 29, 2020Assignee: Koninklijke Philips N.V.Inventors: Thomas Erik Amthor, Peter Koken, Karsten Sommer, Mariya Ivanova Doneva, Peter Boernert
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Publication number: 20200300952Abstract: The invention relates to a method of MR imaging of an object (10) placed in an examination volume of a MR device (1). It is an object of the invention to enable MR imaging using a radial (or spiral) acquisition scheme with a reduced level of motion artefacts. The method of the invention comprises the following sequence of steps: —detecting a momentary motion—induced displacement (?) of the object (10); —attributing the detected displacement (A) to a motion state (M1-M5), each motion state (M1-M5) corresponding to one of a plurality of contiguous ranges of displacements (?); —determining angular coordinates of a radial or spiral k-space profile by incrementing the angular coordinates individually for each motion state (M1-M5) starting from initial angular coordinates; —acquiring the k-space profile; —repeating steps a-d a number of times; and —reconstructing an MR image from at least the k-space profiles attributed to one of the motion states (M1-M5).Type: ApplicationFiled: October 5, 2018Publication date: September 24, 2020Inventors: MARIYA IVANOVA DONEVA, JAN HENDRIK WULBERN, GABRIELE MARIANNE BECK
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Publication number: 20200166596Abstract: The invention relates to a magnetic resonance imaging system (100, 400) comprising a memory (134) for storing machine executable instructions (140) and MRF pulse sequence commands (142). The MRF pulse sequence commands are configured for controlling the magnetic resonance imaging system to acquire MRF magnetic resonance data (144) according to a magnetic resonance fingerprinting protocol. The memory further contains a Fourier transformed magnetic resonance finger printing dictionary (150). The Fourier transformed magnetic resonance finger printing dictionary comprises entries for at least one intrinsic property (152). The magnetic resonance imaging system further comprises a processor (130) for controlling the magnetic resonance imaging system.Type: ApplicationFiled: July 3, 2018Publication date: May 28, 2020Applicant: KONINKLIJKE PHILIPS N.V.Inventors: Karsten Sommer, Thomas Erik Amthor, Jan Jakob Meineke, Peter Koken, Mariya Ivanova Doneva
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Publication number: 20200096589Abstract: The invention provides for a magnetic resonance imaging system (100) for acquiring magnetic resonance data (142) from a subject (118) within a measurement zone (108). The magnetic resonance imaging system (100) comprises: a processor (130) for controlling the magnetic resonance imaging system (100) and a memory (136) storing machine executable instructions (150, 152, 154), pulse sequence commands (140) and a dictionary (144). The pulse sequence commands (140) are configured for controlling the magnetic resonance imaging system (100) to acquire the magnetic resonance data (142) of multiple steady state free precession (SSFP) states per repetition time. The pulse sequence commands (140) are further configured for controlling the magnetic resonance imaging system (100) to acquire the magnetic resonance data (142) of the multiple steady state free precession (SSFP) states according to a magnetic resonance fingerprinting protocol. The dictionary (144) comprises a plurality of tissue parameter sets.Type: ApplicationFiled: December 6, 2017Publication date: March 26, 2020Inventors: KARSTEN SOMMER, MARIYA IVANOVA DONEVA, THOMAS ERIK AMTHOR, PETER KOKEN, JAN JAKOB MEINEKE
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Publication number: 20200088823Abstract: The invention provides for a magnetic resonance imaging system (100) for acquiring magnetic resonance data (146) from a subject (118) from a region of interest (109) within an imaging zone (108). The magnetic resonance imaging system comprises a memory (134) for storing machine executable instructions (140) and pulse sequence commands (142). The pulse sequence commands are configured for controlling the magnetic resonance imaging system to perform magnetization preparation pulses which causes magnetization inversion within the region of interest and initiates a T1 relaxation process. The pulse sequence commands are configured for acquiring portions of the magnetic resonance data as discrete units during a rest and relaxation interval of a heart phase of the subject. The magnetic resonance imaging system further comprises a processor (130) for controlling the magnetic resonance imaging system.Type: ApplicationFiled: December 20, 2017Publication date: March 19, 2020Inventors: CHRISTIAN STEHNING, PETER BOERNERT, THOMAS ERIK AMTHOR, MARIYA IVANOVA DONEVA, JOUKE SMINK, MARC KOUWENHOVEN
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Publication number: 20200041594Abstract: The invention provides for a magnetic resonance imaging (MRI) system (100) that comprises a memory (134) for storing machine executable instructions (140) and MRF pulse sequence commands (142). The MRF pulse sequence commands cause the MRI system to acquire MRF magnetic resonance data (144) according to a magnetic resonance (MR) fingerprinting protocol. The pulse sequence commands are configured for acquiring the MRF magnetic resonance data in two dimensional slices (410, 412, 414, 416, 418, 420), wherein the two dimensional slices have a slice selection direction, wherein the pulse sequence commands comprises a train of pulse sequence repetitions. The train of pulse sequence repetitions comprises a sampling event where the MRF magnetic resonance data is repeatedly sampled. The MRI system further comprises a processor for controlling the magnetic resonance imaging system.Type: ApplicationFiled: March 30, 2018Publication date: February 6, 2020Inventors: THOMAS ERIK AMTHOR, MARIYA IVANOVA DONEVA, KARSTEN SOMMER, PETER KOKEN