Patents by Inventor Mariya Ivanova Doneva

Mariya Ivanova Doneva has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11953571
    Abstract: A medical system including a memory storing machine executable instructions is disclosed. The medical system also includes a computational system. The execution of the machine executable instructions causes the computational system to receive k-space data descriptive of a region of interest of a subject. The k-space data are acquired using a magnetic resonance fingerprinting pulse sequence configured for encoding chemical shifts. The execution of the machine executable instructions also causes the computational system to receive fat peak weights descriptive of a magnetic resonance fat spectrum. The fat peak weights are matched to a pulse train of the magnetic resonance fingerprinting pulse sequence. The execution of the machine executable instructions also causes the computational system to reconstruct a quantitative magnetic resonance image from the k-space data and the fat peak weights.
    Type: Grant
    Filed: March 7, 2022
    Date of Patent: April 9, 2024
    Assignee: Koninklijke Philips N.V.
    Inventors: Dominick Johannes Weidlich, Stefan Ruschke, Elizabeth Huaroc, Mariya Ivanova Doneva, Dimitrios Karampinos
  • Publication number: 20230288514
    Abstract: Disclosed herein is a medical system (100, 300) comprising a memory (110) storing machine executable instructions (120) and an MRF scoring module (122). The MRF scoring module is configured for outputting an MRF quality score (126) in response to receiving MRF data (124) as input. The medical system further comprises a computational system (106) configured for controlling the medical system, wherein execution of the machine executable instructions causes the computational system to: receive (200) the MRF data; receive (202) the MRF quality score in response to inputting the MRF data into an MRF scoring module; append (206) the MRF quality score to the MRF data if the MRF quality score is within a predetermined range (128); and provide (208) a signal (132) if the MRF quality score is outside of the predetermined range.
    Type: Application
    Filed: July 1, 2021
    Publication date: September 14, 2023
    Inventors: Thomas Erik Amthor, Mariya Ivanova Doneva, Peter Koken, Kay Nehrke
  • Patent number: 11579230
    Abstract: The invention provides for a magnetic resonance imaging system (100) for acquiring magnetic resonance data (142) from a subject (118) within a measurement zone (108). The magnetic resonance imaging system (100) comprises: a processor (130) for controlling the magnetic resonance imaging system (100) and a memory (136) storing machine executable instructions (150, 152, 154), pulse sequence commands (140) and a dictionary (144). The pulse sequence commands (140) are configured for controlling the magnetic resonance imaging system (100) to acquire the magnetic resonance data (142) of multiple steady state free precession (SSFP) states per repetition time. The pulse sequence commands (140) are further configured for controlling the magnetic resonance imaging system (100) to acquire the magnetic resonance data (142) of the multiple steady state free precession (SSFP) states according to a magnetic resonance fingerprinting protocol. The dictionary (144) comprises a plurality of tissue parameter sets.
    Type: Grant
    Filed: December 6, 2017
    Date of Patent: February 14, 2023
    Assignee: Koninklijke Philips N.V.
    Inventors: Karsten Sommer, Mariya Ivanova Doneva, Thomas Erik Amthor, Peter Koken, Jan Jakob Meineke
  • Publication number: 20220283252
    Abstract: Disclosed herein is a medical system comprising a memory storing machine executable instructions. The medical system further comprises a computational system. The execution of the machine executable instructions causes the computational system to: receive k-space data descriptive of a region of interest of a subject, wherein the k-space data is acquired using a magnetic resonance fingerprinting pulse sequence configured for encoding chemical shifts; receive fat peak weights descriptive of a magnetic resonance fat spectrum, wherein the fat peak weights are matched to a pulse train of the magnetic resonance fingerprinting pulse sequence; and reconstruct a quantitative magnetic resonance image from the k-space data and the fat peak weighs.
    Type: Application
    Filed: March 7, 2022
    Publication date: September 8, 2022
    Inventors: DOMINICK JOHANNES WEIDLICH, STEFAN RUSCHKE, ELIZABETH HUAROC, MARIYA IVANOVA DONEVA, DIMITRIOS KARAMPINOS
  • Patent number: 11435422
    Abstract: The invention provides for a medical imaging system comprising: a memory for storing machine executable instructions; a processor for controlling the medical instrument. Execution of the machine executable instructions causes the processor to: receive MRF magnetic resonance data acquired according to an MRF magnetic resonance imaging protocol of a region of interest; reconstruct an MRF vector for each voxel of a set of voxels descriptive of the region of interest using the MRF magnetic resonance data according to the MRF magnetic resonance imaging protocol; calculate a preprocessed MRF vector (126) for each of the set of voxels by applying a predetermined preprocessing routine to the MRF vector for each voxel, wherein the predetermined preprocessing routine comprises normalizing the preprocessed MRF vector for each voxel; calculate an outlier map for the set of voxels by assigning an outlier score to the preprocessed MRF vector using a machine learning algorithm.
    Type: Grant
    Filed: September 22, 2020
    Date of Patent: September 6, 2022
    Assignee: Koninklijke Philips N.V.
    Inventors: Thomas Erik Amthor, Mariya Ivanova Doneva, Jan Jakob Meineke
  • Publication number: 20220252688
    Abstract: It is an object of present invention to provide for a faster method of multi-component analysis. This object is achieved by a method for multi-component analysis on MRI measurement data, wherein a component is defined by one or more tissue component parameters among which preferably one is a T2 or T1 value.
    Type: Application
    Filed: April 14, 2020
    Publication date: August 11, 2022
    Inventors: MARIYA IVANOVA DONEVA, MARTIJN ARIE NAGTEGAAL
  • Patent number: 11269037
    Abstract: The invention relates to a method of MR imaging of an object (10) placed in an examination volume of a MR device (1). It is an object of the invention to enable MR imaging using a radial (or spiral) acquisition scheme with a reduced level of motion artefacts. The method of the invention comprises the following sequence of steps: —detecting a momentary motion—induced displacement (?) of the object (10); —attributing the detected displacement (A) to a motion state (M1-M5), each motion state (M1-M5) corresponding to one of a plurality of contiguous ranges of displacements (?); —determining angular coordinates of a radial or spiral k-space profile by incrementing the angular coordinates individually for each motion state (M1-M5) starting from initial angular coordinates; —acquiring the k-space profile; —repeating steps a-d a number of times; and —reconstructing an MR image from at least the k-space profiles attributed to one of the motion states (M1-M5).
    Type: Grant
    Filed: October 5, 2018
    Date of Patent: March 8, 2022
    Assignee: Koninklijke Philips N.V.
    Inventors: Mariya Ivanova Doneva, Jan Hendrik Wulbern, Gabriele Marianne Beck
  • Patent number: 11241162
    Abstract: A method of operating a magnetic resonance imaging system (10) with regard to acquiring multiple-phase dynamic contrast-enhanced magnetic resonance images, the method comprising steps of acquiring (48) a first set of magnetic resonance image data (xpre) prior to administering a contrast agent to the subject of interest (20), by employing a water/fat magnetic resonance signal separation technique, determining (52) a first image of the spatial distribution of fat (Ipre) of at least the portion of the subject of interest (20), acquiring (50) at least a second set of magnetic resonance image data (x2) of at least the portion of the subject of interest (20) after administering the contrast agent to the subject of interest (20), by employing a water/fat magnetic resonance signal separation technique, determining (54) at least a second image of the spatial distribution of fat (I2ph) of at least the portion of the subject of interest (20), applying (56) an image registration method to the second image of the spatial
    Type: Grant
    Filed: March 31, 2015
    Date of Patent: February 8, 2022
    Assignees: Koninklijke Philips N.V., Board of Regents of the University of Texas Systems
    Inventors: Nadine Gdaniec, Peter Boernert, Mariya Ivanova Doneva, Ivan Pedrosa
  • Patent number: 11112478
    Abstract: The invention provides for a magnetic resonance imaging system (100) for acquiring MRF magnetic resonance data (144) from a subject (118) within a region of interest (109). The magnetic resonance imaging system comprises a processor (130) for controlling the magnetic resonance imaging system and a memory (134) for storing machine executable instructions (140) and MRF pulse sequence commands (142). The MRF pulse sequence commands are configured for controlling the magnetic resonance imaging system to acquire the MRF magnetic resonance data according to a magnetic resonance fingerprinting protocol.
    Type: Grant
    Filed: March 30, 2018
    Date of Patent: September 7, 2021
    Assignee: Koninklijke Philips N.V.
    Inventors: Peter Boernert, Thomas Erik Amthor, Mariya Ivanova Doneva, Fabian Wenzel
  • Patent number: 11092659
    Abstract: A magnetic resonance imaging (MRI) system (100) includes a memory (134) for storing machine executable instructions (140) and magnetic resonance fingerprinting (MRF) pulse sequence commands (142) which cause the MRI system to acquire MRF magnetic resonance data (144) according to an MRF protocol. The pulse sequence commands are configured for acquiring the MRF magnetic resonance data in two-dimensional slices (410, 412, 414, 416, 418, 420), having a slice selection direction. A train of pulse sequence repetitions includes a sampling event where the MRF data is repeatedly sampled.
    Type: Grant
    Filed: March 30, 2018
    Date of Patent: August 17, 2021
    Assignee: Koninklijke Philips N.V.
    Inventors: Thomas Erik Amthor, Mariya Ivanova Doneva, Karsten Sommer, Peter Koken
  • Patent number: 11085985
    Abstract: A magnetic resonance imaging (MRI) system includes a memory for storing machine executable instructions and MRF pulse sequence commands. The MRF pulse sequence commands are configured for controlling the MRI system to acquire MRF magnetic resonance data according to a magnetic resonance fingerprinting protocol. The memory further includes a Fourier transformed magnetic resonance finger printing dictionary. The finger printing dictionary includes entries for at least one intrinsic property.
    Type: Grant
    Filed: July 3, 2018
    Date of Patent: August 10, 2021
    Assignee: Koninklijke Philips N.V.
    Inventors: Karsten Sommer, Thomas Erik Amthor, Jan Jakob Meineke, Peter Koken, Mariya Ivanova Doneva
  • Publication number: 20210109180
    Abstract: The invention provides for a magnetic resonance imaging system (100) for acquiring MRF magnetic resonance data (144) from a subject (118) within a region of interest (109). The magnetic resonance imaging system comprises a processor (130) for controlling the magnetic resonance imaging system and a memory (134) for storing machine executable instructions (140) and MRF pulse sequence commands (142). The MRF pulse sequence commands are configured for controlling the magnetic resonance imaging system to acquire the MRF magnetic resonance data according to a magnetic resonance fingerprinting protocol.
    Type: Application
    Filed: March 30, 2018
    Publication date: April 15, 2021
    Inventors: PETER BOERNERT, THOMAS ERIK AMTHOR, MARIYA IVANOVA DONEVA, FABIAN WENZEL
  • Publication number: 20210003650
    Abstract: The invention provides for a medical imaging system comprising: a memory for storing machine executable instructions; a processor for controlling the medical instrument. Execution of the machine executable instructions causes the processor to: receive MRF magnetic resonance data acquired according to an MRF magnetic resonance imaging protocol of a region of interest; reconstruct an MRF vector for each voxel of a set of voxels descriptive of the region of interest using the MRF magnetic resonance data according to the MRF magnetic resonance imaging protocol; calculate a preprocessed MRF vector (126) for each of the set of voxels by applying a predetermined preprocessing routine to the MRF vector for each voxel, wherein the predetermined preprocessing routine comprises normalizing the preprocessed MRF vector for each voxel; calculate an outlier map for the set of voxels by assigning an outlier score to the preprocessed MRF vector using a machine learning algorithm.
    Type: Application
    Filed: September 22, 2020
    Publication date: January 7, 2021
    Inventors: Thomas Erik AMTHOR, Mariya Ivanova DONEVA, Jan Jakob MEINEKE
  • Patent number: 10816625
    Abstract: The invention provides for a magnetic resonance imaging system (100) for acquiring magnetic resonance data (142) from a subject (118) within an imaging zone (108). The magnetic resonance imaging system comprises a memory (134, 136) for storing machine executable instructions (160), and pulse sequence commands (140, 400, 502, 600, 700), wherein the pulse sequence commands are configured to cause the magnetic imaging resonance system to acquire the magnetic resonance data according to a magnetic resonance fingerprinting technique. The pulse sequence commands are further configured to control the magnetic resonance imaging system to perform spatial encoding using a zero echo time magnetic resonance imaging protocol.
    Type: Grant
    Filed: April 26, 2017
    Date of Patent: October 27, 2020
    Assignee: Koninklijke Philips N.V.
    Inventors: Peter Bornert, Kay Nehrke, Mariya Ivanova Doneva, Thomas Erik Amthor, Peter Koken, George Randall Duensing
  • Patent number: 10788556
    Abstract: A magnetic resonance imaging system (100) acquires magnetic resonance data (142) from a subject (118) within a measurement zone (108). Pulse sequence commands (140) control the magnetic resonance imaging system to acquire the magnetic resonance data according to a magnetic resonance fingerprinting protocol. The pulse sequence commands are configured for controlling the magnetic resonance imaging system to repeatedly generate an RF pulse train (300) and acquire the magnetic resonance data as multiple k-space traces. The machine executable instructions causes the processor to: sequentially acquire (200) the multiple k-space traces of magnetic resonance data by controlling the magnetic resonance imaging system with pulse sequence commands and calculate (202) the abundance of each of a set of predetermined substances for k-space traces that are acquired after a predetermined number of k-space traces of the multiple k-space traces has been acquired and the acquired magnetization has reached a steady state.
    Type: Grant
    Filed: February 6, 2017
    Date of Patent: September 29, 2020
    Assignee: Koninklijke Philips N.V.
    Inventors: Thomas Erik Amthor, Peter Koken, Karsten Sommer, Mariya Ivanova Doneva, Peter Boernert
  • Publication number: 20200300952
    Abstract: The invention relates to a method of MR imaging of an object (10) placed in an examination volume of a MR device (1). It is an object of the invention to enable MR imaging using a radial (or spiral) acquisition scheme with a reduced level of motion artefacts. The method of the invention comprises the following sequence of steps: —detecting a momentary motion—induced displacement (?) of the object (10); —attributing the detected displacement (A) to a motion state (M1-M5), each motion state (M1-M5) corresponding to one of a plurality of contiguous ranges of displacements (?); —determining angular coordinates of a radial or spiral k-space profile by incrementing the angular coordinates individually for each motion state (M1-M5) starting from initial angular coordinates; —acquiring the k-space profile; —repeating steps a-d a number of times; and —reconstructing an MR image from at least the k-space profiles attributed to one of the motion states (M1-M5).
    Type: Application
    Filed: October 5, 2018
    Publication date: September 24, 2020
    Inventors: MARIYA IVANOVA DONEVA, JAN HENDRIK WULBERN, GABRIELE MARIANNE BECK
  • Publication number: 20200166596
    Abstract: The invention relates to a magnetic resonance imaging system (100, 400) comprising a memory (134) for storing machine executable instructions (140) and MRF pulse sequence commands (142). The MRF pulse sequence commands are configured for controlling the magnetic resonance imaging system to acquire MRF magnetic resonance data (144) according to a magnetic resonance fingerprinting protocol. The memory further contains a Fourier transformed magnetic resonance finger printing dictionary (150). The Fourier transformed magnetic resonance finger printing dictionary comprises entries for at least one intrinsic property (152). The magnetic resonance imaging system further comprises a processor (130) for controlling the magnetic resonance imaging system.
    Type: Application
    Filed: July 3, 2018
    Publication date: May 28, 2020
    Applicant: KONINKLIJKE PHILIPS N.V.
    Inventors: Karsten Sommer, Thomas Erik Amthor, Jan Jakob Meineke, Peter Koken, Mariya Ivanova Doneva
  • Publication number: 20200096589
    Abstract: The invention provides for a magnetic resonance imaging system (100) for acquiring magnetic resonance data (142) from a subject (118) within a measurement zone (108). The magnetic resonance imaging system (100) comprises: a processor (130) for controlling the magnetic resonance imaging system (100) and a memory (136) storing machine executable instructions (150, 152, 154), pulse sequence commands (140) and a dictionary (144). The pulse sequence commands (140) are configured for controlling the magnetic resonance imaging system (100) to acquire the magnetic resonance data (142) of multiple steady state free precession (SSFP) states per repetition time. The pulse sequence commands (140) are further configured for controlling the magnetic resonance imaging system (100) to acquire the magnetic resonance data (142) of the multiple steady state free precession (SSFP) states according to a magnetic resonance fingerprinting protocol. The dictionary (144) comprises a plurality of tissue parameter sets.
    Type: Application
    Filed: December 6, 2017
    Publication date: March 26, 2020
    Inventors: KARSTEN SOMMER, MARIYA IVANOVA DONEVA, THOMAS ERIK AMTHOR, PETER KOKEN, JAN JAKOB MEINEKE
  • Publication number: 20200088823
    Abstract: The invention provides for a magnetic resonance imaging system (100) for acquiring magnetic resonance data (146) from a subject (118) from a region of interest (109) within an imaging zone (108). The magnetic resonance imaging system comprises a memory (134) for storing machine executable instructions (140) and pulse sequence commands (142). The pulse sequence commands are configured for controlling the magnetic resonance imaging system to perform magnetization preparation pulses which causes magnetization inversion within the region of interest and initiates a T1 relaxation process. The pulse sequence commands are configured for acquiring portions of the magnetic resonance data as discrete units during a rest and relaxation interval of a heart phase of the subject. The magnetic resonance imaging system further comprises a processor (130) for controlling the magnetic resonance imaging system.
    Type: Application
    Filed: December 20, 2017
    Publication date: March 19, 2020
    Inventors: CHRISTIAN STEHNING, PETER BOERNERT, THOMAS ERIK AMTHOR, MARIYA IVANOVA DONEVA, JOUKE SMINK, MARC KOUWENHOVEN
  • Publication number: 20200041594
    Abstract: The invention provides for a magnetic resonance imaging (MRI) system (100) that comprises a memory (134) for storing machine executable instructions (140) and MRF pulse sequence commands (142). The MRF pulse sequence commands cause the MRI system to acquire MRF magnetic resonance data (144) according to a magnetic resonance (MR) fingerprinting protocol. The pulse sequence commands are configured for acquiring the MRF magnetic resonance data in two dimensional slices (410, 412, 414, 416, 418, 420), wherein the two dimensional slices have a slice selection direction, wherein the pulse sequence commands comprises a train of pulse sequence repetitions. The train of pulse sequence repetitions comprises a sampling event where the MRF magnetic resonance data is repeatedly sampled. The MRI system further comprises a processor for controlling the magnetic resonance imaging system.
    Type: Application
    Filed: March 30, 2018
    Publication date: February 6, 2020
    Inventors: THOMAS ERIK AMTHOR, MARIYA IVANOVA DONEVA, KARSTEN SOMMER, PETER KOKEN