Patents by Inventor Mariya Ivanova Doneva

Mariya Ivanova Doneva has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10509086
    Abstract: The invention provides for a method of operating an instrument (100). The instrument comprises a magnetic resonance system (102) for measuring dictionary magnetic resonance data (154) from a measurement zone (108). The magnetic resonance system comprises a magnet (104) for generating a main magnetic field within the measurement zone. The magnetic resonance system comprises a test fixture (124) for holding a test sample (132) within the measurement zone. The test fixture comprises a supplementary magnetic field coil (126) and a magnetic resonance antenna (128).
    Type: Grant
    Filed: June 8, 2016
    Date of Patent: December 17, 2019
    Assignee: Koninklijke Philips N.V.
    Inventors: Thomas Erik Amthor, Peter Boernert, Mariya Ivanova Doneva, Wim Crooijmans
  • Patent number: 10345407
    Abstract: The invention provides for a method of operating a magnetic resonance system for acquiring magnetic resonance data (152) from a phantom (124) within a measurement (zone 108). The phantom comprises a known volume of at least one predetermined substance ((128), 130). The method comprises the step of acquiring (300) the magnetic resonance data by controlling the magnetic resonance system with pulse sequence instructions (150). The pulse sequence instructions cause the magnetic resonance system to acquire the magnetic resonance data according to a magnetic resonance fingerprinting technique. The pulse sequence instructions specify a train of pulse sequence repetitions. Each pulse sequence repetition has a repetition time chosen from a distribution of repetition times. Each pulse sequence repetition comprises a radio frequency pulse chosen from a distribution of radio frequency pulses. The distribution of radio frequency pulses cause magnetic spins to rotate to a distribution of flip angles.
    Type: Grant
    Filed: January 22, 2016
    Date of Patent: July 9, 2019
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Peter Boernert, Mariya Ivanova Doneva, Thomas Erik Amthor, Peter Koken, Jochen Keupp
  • Patent number: 10321845
    Abstract: The invention provides for a magnetic resonance imaging system (100) which comprise a magnet (104) and a magnetic field gradient generator (110, 112) for generating a gradient magnetic field within an imaging zone (108). The gradient magnetic field is aligned with a predetermined direction. The magnetic resonance imaging system further comprise a memory (134, 136) for storing machine executable instructions (150, 152, 154), a pre-calculated magnetic resonance fingerprinting dictionary (144), and pulse sequence instructions (140). The pulse sequence instructions cause the magnetic resonance imaging system to acquire the magnetic resonance data according to a magnetic resonance fingerprinting technique. The magnetic resonance fingerprinting technique encodes the magnetic resonance data as slices (125).
    Type: Grant
    Filed: October 30, 2015
    Date of Patent: June 18, 2019
    Assignee: Koninklijke Philips N.V.
    Inventors: Thomas Erik Amthor, Mariya Ivanova Doneva, Peter Koken, Jochen Keupp, Peter Boernert
  • Publication number: 20190137585
    Abstract: The invention provides for a magnetic resonance imaging system (100) for acquiring magnetic resonance data (142) from a subject (118) within an imaging zone (108). The magnetic resonance imaging system comprises a memory (134, 136) for storing machine executable instructions (160), and pulse sequence commands (140, 400, 502, 600, 700), wherein the pulse sequence commands are configured to cause the magnetic imaging resonance system to acquire the magnetic resonance data according to a magnetic resonance fingerprinting technique. The pulse sequence commands are further configured to control the magnetic resonance imaging system to perform spatial encoding using a zero echo time magnetic resonance imaging protocol.
    Type: Application
    Filed: April 26, 2017
    Publication date: May 9, 2019
    Inventors: PETER BORNERT, KAY NEHRKE, MARIYA IVANOVA DONEVA, THOMAS ERIK AMTHOR, PETER KOKEN, GEORGE RANDALL DUENSING
  • Publication number: 20190033413
    Abstract: The invention provides for a magnetic resonance imaging system (100) for acquiring magnetic resonance data (142) from a subject (118) within a measurement zone (108), wherein the magnetic resonance imaging system comprises: a processor (130) for controlling the magnetic resonance imaging system and a memory (136) for storing machine executable instructions (150, 152, 154) and pulse sequence commands (140). The pulse sequence commands for controlling the magnetic resonance imaging system to acquire the magnetic resonance data according to a magnetic resonance fingerprinting protocol. The pulse sequence commands are configured for controlling the magnetic resonance imaging system to generate an RF pulse train (300). The pulse sequence commands are configured for controlling the magnetic resonance imaging system to acquire the magnetic resonance data as multiple k-space traces.
    Type: Application
    Filed: February 6, 2017
    Publication date: January 31, 2019
    Applicant: Koninklijke Philips N.V.
    Inventors: Thomas Erik AMTHOR, Peter KOKEN, Karsten SOMMER, Mariya Ivanova DONEVA, Peter BOERNERT
  • Patent number: 10107884
    Abstract: A parallel magnetic resonance imaging system (1) includes at least one radio frequency (RF) coil (10, 12) with a plurality of coil elements, a smart select unit (24), a parallel imaging parameter unit (28), and a sequence control (16). The smart select unit (24), from a pre-scan or prior scan of a subject with the at least one RF coil, constructs (60) a signal map and a plurality of noise maps based on different sets of reduction factors. The parallel imaging parameter unit (28) selects a set of reduction factors corresponding to a noise map which includes a highest signal-to-noise ratio (SNR). The sequence control (16) performs a magnetic resonance imaging scan of the subject based on the selected reduction factors.
    Type: Grant
    Filed: March 12, 2014
    Date of Patent: October 23, 2018
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Peter Boernert, Michel Paul Jurriaan Jurrissen, Mariya Ivanova Doneva, Adrianus Joseph Willibrordus Duijndam, Kay Nehrke
  • Patent number: 10088543
    Abstract: The invention relates to a method of MR imaging of an object (10) placed in an examination volume of a MR device (1). The method comprises the steps of: —subjecting the object (10) to an imaging sequence comprising phase-modulated multi-slice RF pulses for simultaneously exciting two or more spatially separate image slices, —acquiring MR signals, wherein the MR signals are received in parallel via a set of at least two RF coils (11, 12, 13) having different spatial sensitivity profiles within the examination volume, and —reconstructing a MR image for each image slice from the acquired MR signals, wherein MR signal contributions from the different image slices are separated on the basis of the spatial sensitivity profiles of the at least two RF coils (11, 12, 13) and on the basis of the phase modulation scheme of the RF pulses.
    Type: Grant
    Filed: March 11, 2014
    Date of Patent: October 2, 2018
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Peter Bornert, Mariya Ivanova Doneva, Kay Nehrke
  • Patent number: 10073160
    Abstract: A magnetic resonance imaging method includes acquisition of datasets of magnetic resonance data from an object. At least some of the datasets are undersampled in k-space. Each dataset relating to a motion state of the object. Images are reconstructed from each of the datasets by way of a compressed sensing reconstruction. Motion correction is applied to the reconstructed images relative to a selected motion state, so as to generate motion corrected images. A diagnostic image for the selected motion state is derived, e.g. by averaging from the motion corrected images.
    Type: Grant
    Filed: April 11, 2012
    Date of Patent: September 11, 2018
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Peter Boernert, Mariya Ivanova Doneva, Christian Stehning
  • Publication number: 20180180692
    Abstract: The invention provides for a method of operating an instrument (100). The instrument comprises a magnetic resonance system (102) for measuring dictionary magnetic resonance data (154) from a measurement zone (108). The magnetic resonance system comprises a magnet (104) for generating a main magnetic field within the measurement zone. The magnetic resonance system comprises a test fixture (124) for holding a test sample (132) within the measurement zone. The test fixture comprises a supplementary magnetic field coil (126) and a magnetic resonance antenna (128).
    Type: Application
    Filed: June 8, 2016
    Publication date: June 28, 2018
    Inventors: THOMAS ERIK AMTHOR, PETER BOERNERT, MARIYA IVANOVA DONEVA, WIM CROOIJMANS
  • Patent number: 9964615
    Abstract: The invention relates to a method of MR imaging of an object (10) placed in an examination volume of a MR device (1). The method comprises the steps of: subjecting the object (10) to an imaging sequence for acquiring MR signal data, wherein the MR signal data are acquired as a function of k-space position and time by using an irregular k-space sampling pattern with sub-sampling of k-space; reconstructing MR image data from the MR signal data, which MR image data comprise spatial dimensions and a frequency dimension, sparsity of the MR image data in a transform domain being exploited for suppressing sub-sampling artefacts in the MR image data. Moreover, the invention relates to a MR device (1) and to a computer program.
    Type: Grant
    Filed: March 12, 2014
    Date of Patent: May 8, 2018
    Assignee: Koninklijke Philips N.V.
    Inventors: Miha Fuderer, Mariya Ivanova Doneva
  • Publication number: 20180106876
    Abstract: The invention provides for a magnetic resonance system (100) comprising a magnet (104) for generating a main magnetic field within the measurement zone and a magnetic field gradient system (110, 112) for generating a gradient magnetic field within the measurement zone in at least one direction by supplying current to a set of magnetic gradient coils (112) for each of the at least one direction. Instructions cause a a processor (130) controlling the magnetic resonance system, wherein execution of the machine executable instructions causes the processor to acquire (200) the magnetic resonance data by controlling the magnetic resonance system with pulse sequence commands. The pulse sequence commands (140) cause the magnetic resonance system to acquire the magnetic resonance data according to a magnetic resonance fingerprinting technique. The pulse sequence commands specify a train (500) of pulse sequence repetitions (502, 504), each with a fixed repetition time (302).
    Type: Application
    Filed: April 13, 2016
    Publication date: April 19, 2018
    Inventors: TIM NIELSEN, PETER BOERNERT, KAY NEHRKE, THOMAS ERIK AMTHOR, MARIYA IVANOVA DONEVA
  • Publication number: 20180031653
    Abstract: The invention provides for a method of operating a magnetic resonance system for acquiring magnetic resonance data (152) from a phantom (124) within a measurement (zone 108). The phantom comprises a known volume of at least one predetermined substance ((128), 130). The method comprises the step of acquiring (300) the magnetic resonance data by controlling the magnetic resonance system with pulse sequence instructions (150). The pulse sequence instructions cause the magnetic resonance system to acquire the magnetic resonance data according to a magnetic resonance fingerprinting technique. The pulse sequence instructions specify a train of pulse sequence repetitions. Each pulse sequence repetition has a repetition time chosen from a distribution of repetition times. Each pulse sequence repetition comprises a radio frequency pulse chosen from a distribution of radio frequency pulses. The distribution of radio frequency pulses cause magnetic spins to rotate to a distribution of flip angles.
    Type: Application
    Filed: January 22, 2016
    Publication date: February 1, 2018
    Inventors: PETER BOERNERT, MARIYA IVANOVA DONEVA, THOMAS ERIK AMTHOR, PETER KOKEN, JOCHEN KEUPP
  • Publication number: 20170319097
    Abstract: The invention provides for a magnetic resonance imaging system (100) which comprise a magnet (104) and a magnetic field gradient generator (110, 112) for generating a gradient magnetic field within an imaging zone (108). The gradient magnetic field is aligned with a predetermined direction. The magnetic resonance imaging system further comprise a memory (134, 136) for storing machine executable instructions (150, 152, 154), a pre-calculated magnetic resonance fingerprinting dictionary (144), and pulse sequence instructions (140). The pulse sequence instructions cause the magnetic resonance imaging system to acquire the magnetic resonance data according to a magnetic resonance fingerprinting technique. The magnetic resonance fingerprinting technique encodes the magnetic resonance data as slices (125).
    Type: Application
    Filed: October 30, 2015
    Publication date: November 9, 2017
    Inventors: THOMAS ERIK AMTHOR, MARIYA IVANOVA DONEVA, PETER KOKEN, JOCHEN KEUPP, PETER BOERNERT
  • Publication number: 20170315193
    Abstract: The invention provides for a magnetic resonance system (100) for acquiring a magnetic resonance data from a subject (118) within a measurement zone (108) according to a magnetic resonance fingerprinting technique. The pulse sequence comprises a train of pulse sequence repetitions (302, 304). Each pulse sequence repetition has a repetition time chosen from a distribution of repetition times. Each pulse sequence repetition comprises a radio frequency pulse (306) chosen from a distribution of radio frequency pulses. The distribution of radio frequency pulses cause magnetic spins to rotate to a distribution of flip angles, and each pulse sequence repetition comprises a sampling event (310) at a sampling time chosen from a distribution of sampling times. Each pulse sequence repetition of the pulse sequence comprises a first 180 degree RF pulse (308) performed at a first temporal midpoint between the radio frequency pulse and the sampling event to refocus the magnetic resonance signal.
    Type: Application
    Filed: November 5, 2015
    Publication date: November 2, 2017
    Applicant: KONINKLIJKE PHILIPS N.V.
    Inventors: THOMAS ERIK AMTHOR, MARIYA IVANOVA DONEVA, PETER KOKEN, JOCHEN KEUPP, PETER BOERNERT
  • Patent number: 9733328
    Abstract: The invention relates to a method of MR imaging of at least a portion of a body (10) of a patient placed in an examination volume of a MR device (1), the method comprising the steps of: —subjecting the portion of the body (10) to a first imaging sequence for acquiring a first signal data set (21); —subjecting the portion of the body (10) to a second imaging sequence for acquiring a second signal data set (23), wherein the imaging parameters of the second imaging sequence differ from the imaging parameters of the first imaging sequence; —reconstructing a MR image from the second signal data set (23) by means of regularization using the first signal data set (21) as prior information. Moreover, the invention relates to a MR device (1) and to a computer program for a MR device (1).
    Type: Grant
    Filed: February 28, 2012
    Date of Patent: August 15, 2017
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Mariya Ivanova Doneva, Stefanie Remmele, Peter Börnert, Peter Mazurkewitz, Julien Senegas, Jochen Keupp, Kay Nehrke
  • Publication number: 20170027472
    Abstract: A method of operating a magnetic resonance imaging system (10) with regard to acquiring multiple-phase dynamic contrast-enhanced magnetic resonance images, the method comprising steps of acquiring (48) a first set of magnetic resonance image data (xpre) prior to administering a contrast agent to the subject of interest (20), by employing a water/fat magnetic resonance signal separation technique, determining (52) a first image of the spatial distribution of fat (Ipre) of at least the portion of the subject of interest (20), acquiring (50) at least a second set of magnetic resonance image data (x2) of at least the portion of the subject of interest (20) after administering the contrast agent to the subject of interest (20), by employing a water/fat magnetic resonance signal separation technique, determining (54) at least a second image of the spatial distribution of fat (I2ph) of at least the portion of the subject of interest (20), applying (56) an image registration method to the second image of the spatial
    Type: Application
    Filed: March 31, 2015
    Publication date: February 2, 2017
    Inventors: NADINE GDANIEC, PETER BOERNERT, MARIYA IVANOVA DONEVA, IVAN PEDROSA
  • Publication number: 20160291106
    Abstract: The invention relates to a method of MR imaging of an object (10) placed in an examination volume of a MR device (1). The method comprises the steps of: subjecting the object (10) to an imaging sequence for acquiring MR signal data, wherein the MR signal data are acquired as a function of k-space position and time by using an irregular k-space sampling pattern with sub-sampling of k-space; reconstructing MR image data from the MR signal data, which MR image data comprise spatial dimensions and a frequency dimension, sparsity of the MR image data in a transform domain being exploited for suppressing sub-sampling artefacts in the MR image data. Moreover, the invention relates to a MR device (1) and to a computer program.
    Type: Application
    Filed: March 12, 2014
    Publication date: October 6, 2016
    Inventors: Miha Fuderer, Mariya Ivanova Doneva
  • Publication number: 20160061921
    Abstract: The present invention relates to a magnetic resonance imaging, MRI, system (200) for acquiring magnetic resonance data from a target volume in a subject (218), the MRI system (200) comprising a memory (236) for storing machine executable instructions; and a processor (230) for controlling the MRI system (200), wherein execution of the machine executable instructions causes the processor (230) to use a first MRI sequence (401) containing a first selective RF pulse (413) followed by a first excitation RF pulse (415) to control the MRI system (200) to selectively excite and saturate exchangeable amide protons within a first frequency range in the target volume; irradiate said target volume with the first excitation RF pulse (415) that is adapted to excite bulk water protons in the target volume; and acquire first magnetic resonance imaging data from the target volume in response to the first excitation RF pulse (415); use a second MRI sequence (403) containing a second selective RF pulse (423) followed by a seco
    Type: Application
    Filed: March 26, 2014
    Publication date: March 3, 2016
    Inventors: ULRICH KATSCHER, MARIYA IVANOVA DONEVA, CHRISTIAN STEHNING, JOHAN SAMUEL VAN DEN BRINK, JOCHEN KEUPP
  • Publication number: 20160054418
    Abstract: The present invention relates to a magnetic resonance imaging MRI system (100) for acquiring magnetic resonance data from a target volume in a subject (118), the magnetic resonance imaging system (100) comprises: a memory (136) for storing machine executable instructions; and a processor (130) for controlling the MRI system (100), wherein execution of the machine executable instructions causes the processor (130) to: determine an energy distribution (301-305) over a k-space domain of the target volume; receive a reduction factor representing a degree of under-sampling of the k-space domain; derive from the energy distribution (301-305) and the received reduction factor a sampling density function; derive from the sampling density function an energy dependent sampling pattern of the k-space domain; control the MRI system (100) to acquire under-sampled k-space data using a pulse sequence that samples the k-space domain along the derived sampling pattern; apply a compressed sensing reconstruction to the acquired
    Type: Application
    Filed: March 7, 2014
    Publication date: February 25, 2016
    Inventors: MARIYA IVANOVA DONEVA, MICHAEL GUNTER HELLE, PETER BOERNERT
  • Publication number: 20160018499
    Abstract: The invention relates to a method of MR imaging of an object (10) placed in an examination volume of a MR device (1). The method comprises the steps of: —subjecting the object (10) to an imaging sequence comprising phase-modulated multi-slice RF pulses for simultaneously exciting two or more spatially separate image slices, —acquiring MR signals, wherein the MR signals are received in parallel via a set of at least two RF coils (11, 12, 13) having different spatial sensitivity profiles within the examination volume, and —reconstructing a MR image for each image slice from the acquired MR signals, wherein MR signal contributions from the different image slices are separated on the basis of the spatial sensitivity profiles of the at least two RF coils (11, 12, 13) and on the basis of the phase modulation scheme of the RF pulses.
    Type: Application
    Filed: March 11, 2014
    Publication date: January 21, 2016
    Applicant: KONINKLIJKE PHILIPS N.V.
    Inventors: PETER BORNERT, MARIYA IVANOVA DONEVA, KAY NEHRKE