Patents by Inventor Mark A. Conkling

Mark A. Conkling has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tobacco products with reduced nicotine
    Patent number: 7795509
    Abstract: DNA encoding a plant quinolate phosphoribosyl transferase (QPRTase) enzyme, and constructs comprising such DNA are provided. Methods of altering quinolate phosphoribosyl transferase expression are provided.
    Type: Grant
    Filed: May 3, 2006
    Date of Patent: September 14, 2010
    Assignee: North Carolina State University
    Inventors: Mark A. Conkling, Wen Song, Nandini Mendu
  • Tobacco products with increased nicotine
    Patent number: 7645925
    Abstract: DNA encoding a plant quinolate phosphoribosyl transferase (QPRTase) enzyme, and constructs comprising such DNA are provided. Methods of altering quinolate phosphoribosyl transferase expression are provided.
    Type: Grant
    Filed: May 3, 2006
    Date of Patent: January 12, 2010
    Assignee: North Carolina State University
    Inventors: Mark A. Conkling, Wen Song, Nandini Mendu
  • Regulation of quinolate phosphoribosyl transferase expression
    Patent number: 7605308
    Abstract: DNA encoding a plant quinolate phosphoribosyl transferase (QPRTase) enzyme, and constructs comprising such DNA are provided. Methods of altering quinolate phosphoribosyl transferase expression are provided.
    Type: Grant
    Filed: September 24, 2001
    Date of Patent: October 20, 2009
    Assignee: North Carolina State University
    Inventors: Mark A. Conkling, Wen Song, Nandini Mendu
  • Methods and compositions for protein production in tobacco plants with reduced nicotine
    Patent number: 7425670
    Abstract: DNA encoding a plant quinolate phosphoribosyl transferase (QPRTase) enzyme, and constructs comprising such DNA are provided. Methods of altering quinolate phosphoribosyl transferase expression are provided.
    Type: Grant
    Filed: May 3, 2006
    Date of Patent: September 16, 2008
    Assignee: North Carolina State University
    Inventors: Mark A. Conkling, Wen Song, Nandini Mendu
  • Regulation of quinolate phosphoribosyl transferase expression
    Patent number: 7408098
    Abstract: DNA encoding a plant quinolate phosphoribosyl transferase (QPRTase) enzyme, and constructs comprising such DNA are provided. Methods of altering quinolate phosphoribosyl transferase expression are provided.
    Type: Grant
    Filed: December 30, 2003
    Date of Patent: August 5, 2008
    Assignee: North Carolina State University
    Inventors: Mark A. Conkling, Wen Song, Nandini Mendu
  • Regulation of quinolate phosphoribosyl transferase expression
    Patent number: 7304220
    Abstract: DNA encoding a plant quinolate phosphoribosyl transferase (QPRTase) enzyme, and constructs comprising such DNA are provided. Methods of altering quinolate phosphoribosyl transferase expression are provided.
    Type: Grant
    Filed: January 31, 2003
    Date of Patent: December 4, 2007
    Assignee: North Carolina State University
    Inventors: Mark A. Conkling, Wen Song, Nandini Mendu
  • Plant promoter sequence
    Patent number: 7192771
    Abstract: Aspects of the invention concern an isolated nucleic acid consisting of the nucleotide sequence of SEQ ID NO:1 operably associated with a heterologous nucleotide sequence.
    Type: Grant
    Filed: August 28, 2001
    Date of Patent: March 20, 2007
    Assignee: North Carolina State University
    Inventors: Mark A. Conkling, Yan Li
  • Promoter fragment that is recognized by the product of the tobacco Nic gene
    Patent number: 6911541
    Abstract: The present application describes an isolated promoter fragment that is recognized by the product of the Nic gene of tobacco.
    Type: Grant
    Filed: August 28, 2001
    Date of Patent: June 28, 2005
    Assignee: North Carolina State University
    Inventors: Mark A. Conkling, Yan Li
  • Modifying nicotine and nitrosamine levels in tobacco
    Patent number: 6907887
    Abstract: The present invention generally relates to tobacco and tobacco products having a reduced amount of nicotine and/or tobacco specific nitrosamines (TSNA). More specifically, several ways to make tobacco plants that have reduced nicotine and TSNA levels have been discovered. Embodiments include tobacco harvested from said tobacco plants, cured tobacco from said tobacco plants, tobacco products made with said cured tobacco and methods of making these compositions.
    Type: Grant
    Filed: December 5, 2003
    Date of Patent: June 21, 2005
    Assignee: Vector Tobacco Ltd.
    Inventor: Mark A. Conkling
  • Regulation of quinolate phosphoribosyl transferase expression
    Publication number: 20040168211
    Abstract: DNA encoding a plant quinolate phosphoribosyl transferase (QPRTase) enzyme, and constructs comprising such DNA are provided. Methods of altering quinolate phosphoribosyl transferase expression are provided.
    Type: Application
    Filed: December 30, 2003
    Publication date: August 26, 2004
    Inventors: Mark A. Conkling, Wen Song, Nandini Mendu
  • Modifying nicotine and nitrosamine levels in tobacco
    Publication number: 20040144397
    Abstract: The present invention generally relates to tobacco and tobacco products having a reduced amount of nicotine and/or tobacco specific nitrosamines (TSNA). More specifically, several ways to make tobacco plants that have reduced nicotine and TSNA levels have been discovered. Embodiments include tobacco harvested from said tobacco plants, cured tobacco from said tobacco plants, tobacco products made with said cured tobacco and methods of making these compositions.
    Type: Application
    Filed: December 4, 2003
    Publication date: July 29, 2004
    Inventor: Mark A. Conkling
  • Transgenic plants containing molecular decoys that alter protein content therein
    Publication number: 20040103454
    Abstract: The present application describes isolated nucleic acids that contain a Nic gene product responsive element, and the use thereof in methods of producing transgenic tobacco plants having reduced levels of nicotine and/or TSNA therein, as well as other plants or host cells that contain altered levels of a protein of interest therein due to inclusion of a cis-acting decoy element therein.
    Type: Application
    Filed: July 14, 2003
    Publication date: May 27, 2004
    Inventors: Mark A. Conkling, Yan Li
  • Putrescine-n-methyltransferase promotor
    Publication number: 20040031074
    Abstract: Putrescine-N-Methyltransferase promoters, particularly promoters isolated from tobacco, are disclosed, along with recombinant nucleic acids containing the same, expression vectors containing the same, and transgenic plants produced therewith. Methods of use thereof are also disclosed.
    Type: Application
    Filed: August 20, 2003
    Publication date: February 12, 2004
    Inventors: Mark A. Conkling, Yan Li
  • Regulation of quinolate phosphoribosyl transferase expression
    Publication number: 20030140366
    Abstract: DNA encoding a plant quinolate phosphoribosyl transferase (QPRTase) enzyme, and constructs comprising such DNA are provided. Methods of altering quinolate phosphoribosyl transferase expression are provided.
    Type: Application
    Filed: January 31, 2003
    Publication date: July 24, 2003
    Inventors: Mark A. Conkling, Wen Song, Nandini Mendu
  • Regulation of quinolate phosphoribosyl transferase expression by transformation with a tobacco quinolate phosphoribosyl transferase nucleic acid
    Patent number: 6586661
    Abstract: DNA encoding a tobacco quinolate phosphoribosyl transferase (QPRTase) enzyme, and constructs comprising such DNA are provided. Methods of altering quinolate phosphoribosyl transferase expression are provided.
    Type: Grant
    Filed: February 10, 1998
    Date of Patent: July 1, 2003
    Assignee: North Carolina State University
    Inventors: Mark A. Conkling, Wen Song, Nandini Mendu
  • Transgenic plants containing molecular decoys that alter protein content therein
    Publication number: 20030018997
    Abstract: The present application describes isolated nucleic acids that contain a Nic gene product responsive element, and the use thereof in methods of producing transgenic tobacco plants having reduced levels of nicotine and/or TSNA therein, as well as other plants or host cells that contain altered levels of a protein of interest therein due to inclusion of a cis-acting decoy element therein.
    Type: Application
    Filed: August 28, 2001
    Publication date: January 23, 2003
    Inventors: Mark A. Conkling, Yan Li
  • Regulation of quinolate phosphoribosyl transferase expression
    Publication number: 20020108151
    Abstract: DNA encoding a plant quinolate phosphoribosyl transferase (QPRTase) enzyme, and constructs comprising such DNA are provided. Methods of altering quinolate phosphoribosyl transferase expression are provided.
    Type: Application
    Filed: September 24, 2001
    Publication date: August 8, 2002
    Inventors: Mark A. Conkling, Wen Song, Nandini Mendu
  • Regulation of quinolate phosphoribosyl transferase expression
    Patent number: 6423520
    Abstract: DNA encoding a plant quinolate phosphoribosyl transferase (QPRTase) enzyme, and constructs comprising such DNA are provided. Methods of altering quinolate phosphoribosyl transferase expression are provided.
    Type: Grant
    Filed: October 29, 1999
    Date of Patent: July 23, 2002
    Assignee: North Carolina State University
    Inventors: Mark A. Conkling, Wen Song, Nandini Mendu
  • Nematode-resistant transgenic plants
    Patent number: 6008436
    Abstract: Nematode-resistant transgenic plants are disclosed. The plants comprise plant cells containing a DNA construct comprising a transcription cassette, which construct comprises, in the 5' to 3' direction, a promoter operable in the plant cells, and a DNA comprising at least a portion of a DNA sequence encoding a nematode-inducible transmembrane pore protein in either the sense or antisense orientation. Intermediates for producing the same along with methods of making and using the same are also disclosed. In an alternate embodiment of the invention, the sense or antisense DNA is replaced with a DNA encoding an enzymatic RNA molecule directed against the mRNA transcript of a DNA sequence encoding a nematode-inducible transmembrane pore protein.
    Type: Grant
    Filed: May 23, 1996
    Date of Patent: December 28, 1999
    Assignee: North Carolina State University
    Inventors: Mark A. Conkling, Charles H. Opperman, Gregoria N. Acedo, Wen Song
  • Root cortex specific gene promoter
    Patent number: 5837876
    Abstract: An isolated DNA molecule which comprises a DNA promoter sequence which directs root cortex specific transcription of a downstream heterologous DNA segment in a plant cell. A DNA construct which comprises an expression cassette comprising, in the 5' to 3' direction, a promoter of the present invention and a heterologous DNA segment positioned downstream from the promoter and operatively associated therewith. Transformed plants, such as tobacco plants, comprise transformed plant cells containing a heterologous DNA construct comprising an expression cassette as described above.
    Type: Grant
    Filed: July 28, 1995
    Date of Patent: November 17, 1998
    Assignee: North Carolina State University
    Inventors: Mark A. Conkling, Nandini Mendu, Wen Song