Patents by Inventor Mark A. Conkling

Mark A. Conkling has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20060185684
    Abstract: The present invention generally relates to the reduction of the harmful effects of orally or transdermally delivered nicotine in conventional tobacco-use cessation programs. More specifically, embodiments concern methods of reducing the harmful effects of nicotine intake, associated with conventional tobacco-use cessation programs, by providing tobacco products, which contain a reduced amount of nicotine and/or tobacco specific nitrosamines (TSNAs).
    Type: Application
    Filed: May 2, 2006
    Publication date: August 24, 2006
    Inventors: Anthony Albino, Mark Conkling, Wendy Jin
  • Publication number: 20060191036
    Abstract: DNA encoding a plant quinolate phosphoribosyl transferase (QPRTase) enzyme, and constructs comprising such DNA are provided. Methods of altering quinolate phosphoribosyl transferase expression are provided.
    Type: Application
    Filed: May 3, 2006
    Publication date: August 24, 2006
    Inventors: Mark Conkling, Wen Song, Nandini Mendu
  • Publication number: 20060191035
    Abstract: DNA encoding a plant quinolate phosphoribosyl transferase (QPRTase) enzyme, and constructs comprising such DNA are provided. Methods of altering quinolate phosphoribosyl transferase expression are provided.
    Type: Application
    Filed: May 3, 2006
    Publication date: August 24, 2006
    Inventors: Mark Conkling, Wen Song, Nandini Mendu
  • Publication number: 20060157072
    Abstract: The present invention generally relates to the reduction of the harmful effects of orally or transdermally delivered nicotine in conventional tobacco-use cessation programs. More specifically, embodiments concern methods of reducing the harmful effects of nicotine intake, associated with conventional tobacco-use cessation programs, by providing tobacco products, which contain a reduced amount of nicotine and/or tobacco specific nitrosamines (TSNAs).
    Type: Application
    Filed: December 2, 2005
    Publication date: July 20, 2006
    Inventors: Anthony Albino, Mark Conkling, Wendy Jin
  • Publication number: 20060060211
    Abstract: The present invention generally relates to tobacco and tobacco products having a reduced amount of nicotine and/or tobacco specific nitrosamines (TSNA). More specifically, several ways to make tobacco plants that have reduced nicotine and TSNA levels have been discovered. Embodiments include tobacco harvested from said tobacco plants, cured tobacco from said tobacco plants, tobacco products made with said cured tobacco and methods of making these compositions.
    Type: Application
    Filed: November 22, 2005
    Publication date: March 23, 2006
    Inventor: Mark Conkling
  • Publication number: 20060057723
    Abstract: The present application describes isolated nucleic acids that contain a Nic gene product responsive element, and the use thereof in methods of producing transgenic tobacco plants having reduced levels of nicotine and/or TSNA therein, as well as other plants or host cells that contain altered levels of a protein of interest therein due to inclusion of a cis-acting decoy element therein.
    Type: Application
    Filed: November 10, 2004
    Publication date: March 16, 2006
    Inventors: Mark Conkling, Yan Li
  • Publication number: 20050161056
    Abstract: The present invention generally relates to tobacco and tobacco products having a reduced amount of nicotine and/or tobacco specific nitrosamines (TSNA). More specifically, several ways to make tobacco plants that have reduced nicotine and TSNA levels have been discovered. Embodiments include tobacco harvested from said tobacco plants, cured tobacco from said tobacco plants, tobacco products made with said cured tobacco and methods of making these compositions.
    Type: Application
    Filed: March 10, 2005
    Publication date: July 28, 2005
    Inventor: Mark Conkling
  • Patent number: 6911541
    Abstract: The present application describes an isolated promoter fragment that is recognized by the product of the Nic gene of tobacco.
    Type: Grant
    Filed: August 28, 2001
    Date of Patent: June 28, 2005
    Assignee: North Carolina State University
    Inventors: Mark A. Conkling, Yan Li
  • Patent number: 6907887
    Abstract: The present invention generally relates to tobacco and tobacco products having a reduced amount of nicotine and/or tobacco specific nitrosamines (TSNA). More specifically, several ways to make tobacco plants that have reduced nicotine and TSNA levels have been discovered. Embodiments include tobacco harvested from said tobacco plants, cured tobacco from said tobacco plants, tobacco products made with said cured tobacco and methods of making these compositions.
    Type: Grant
    Filed: December 5, 2003
    Date of Patent: June 21, 2005
    Assignee: Vector Tobacco Ltd.
    Inventor: Mark A. Conkling
  • Publication number: 20050072047
    Abstract: Aspects of the present invention concern tobacco having reduced nicotine and nitrosamines, which is used to manufacture consumer tobacco products, and methods to produce such tobacco. More specifically, embodiments include methods to reduce nicotine and nitrosamines in tobacco crops by applying auxin, auxin analogs, and jasmonate antagonists during the cultivation of such tobacco crops. Tobacco generated using said methods and consumer tobacco products obtained therefrom are also embodiments.
    Type: Application
    Filed: September 17, 2004
    Publication date: April 7, 2005
    Inventors: Mark Conkling, Yan Li
  • Publication number: 20040168211
    Abstract: DNA encoding a plant quinolate phosphoribosyl transferase (QPRTase) enzyme, and constructs comprising such DNA are provided. Methods of altering quinolate phosphoribosyl transferase expression are provided.
    Type: Application
    Filed: December 30, 2003
    Publication date: August 26, 2004
    Inventors: Mark A. Conkling, Wen Song, Nandini Mendu
  • Publication number: 20040144397
    Abstract: The present invention generally relates to tobacco and tobacco products having a reduced amount of nicotine and/or tobacco specific nitrosamines (TSNA). More specifically, several ways to make tobacco plants that have reduced nicotine and TSNA levels have been discovered. Embodiments include tobacco harvested from said tobacco plants, cured tobacco from said tobacco plants, tobacco products made with said cured tobacco and methods of making these compositions.
    Type: Application
    Filed: December 4, 2003
    Publication date: July 29, 2004
    Inventor: Mark A. Conkling
  • Publication number: 20040103454
    Abstract: The present application describes isolated nucleic acids that contain a Nic gene product responsive element, and the use thereof in methods of producing transgenic tobacco plants having reduced levels of nicotine and/or TSNA therein, as well as other plants or host cells that contain altered levels of a protein of interest therein due to inclusion of a cis-acting decoy element therein.
    Type: Application
    Filed: July 14, 2003
    Publication date: May 27, 2004
    Inventors: Mark A. Conkling, Yan Li
  • Publication number: 20040031074
    Abstract: Putrescine-N-Methyltransferase promoters, particularly promoters isolated from tobacco, are disclosed, along with recombinant nucleic acids containing the same, expression vectors containing the same, and transgenic plants produced therewith. Methods of use thereof are also disclosed.
    Type: Application
    Filed: August 20, 2003
    Publication date: February 12, 2004
    Inventors: Mark A. Conkling, Yan Li
  • Publication number: 20030140366
    Abstract: DNA encoding a plant quinolate phosphoribosyl transferase (QPRTase) enzyme, and constructs comprising such DNA are provided. Methods of altering quinolate phosphoribosyl transferase expression are provided.
    Type: Application
    Filed: January 31, 2003
    Publication date: July 24, 2003
    Inventors: Mark A. Conkling, Wen Song, Nandini Mendu
  • Patent number: 6586661
    Abstract: DNA encoding a tobacco quinolate phosphoribosyl transferase (QPRTase) enzyme, and constructs comprising such DNA are provided. Methods of altering quinolate phosphoribosyl transferase expression are provided.
    Type: Grant
    Filed: February 10, 1998
    Date of Patent: July 1, 2003
    Assignee: North Carolina State University
    Inventors: Mark A. Conkling, Wen Song, Nandini Mendu
  • Publication number: 20030018997
    Abstract: The present application describes isolated nucleic acids that contain a Nic gene product responsive element, and the use thereof in methods of producing transgenic tobacco plants having reduced levels of nicotine and/or TSNA therein, as well as other plants or host cells that contain altered levels of a protein of interest therein due to inclusion of a cis-acting decoy element therein.
    Type: Application
    Filed: August 28, 2001
    Publication date: January 23, 2003
    Inventors: Mark A. Conkling, Yan Li
  • Publication number: 20020108151
    Abstract: DNA encoding a plant quinolate phosphoribosyl transferase (QPRTase) enzyme, and constructs comprising such DNA are provided. Methods of altering quinolate phosphoribosyl transferase expression are provided.
    Type: Application
    Filed: September 24, 2001
    Publication date: August 8, 2002
    Inventors: Mark A. Conkling, Wen Song, Nandini Mendu
  • Patent number: 6423520
    Abstract: DNA encoding a plant quinolate phosphoribosyl transferase (QPRTase) enzyme, and constructs comprising such DNA are provided. Methods of altering quinolate phosphoribosyl transferase expression are provided.
    Type: Grant
    Filed: October 29, 1999
    Date of Patent: July 23, 2002
    Assignee: North Carolina State University
    Inventors: Mark A. Conkling, Wen Song, Nandini Mendu
  • Patent number: 6008436
    Abstract: Nematode-resistant transgenic plants are disclosed. The plants comprise plant cells containing a DNA construct comprising a transcription cassette, which construct comprises, in the 5' to 3' direction, a promoter operable in the plant cells, and a DNA comprising at least a portion of a DNA sequence encoding a nematode-inducible transmembrane pore protein in either the sense or antisense orientation. Intermediates for producing the same along with methods of making and using the same are also disclosed. In an alternate embodiment of the invention, the sense or antisense DNA is replaced with a DNA encoding an enzymatic RNA molecule directed against the mRNA transcript of a DNA sequence encoding a nematode-inducible transmembrane pore protein.
    Type: Grant
    Filed: May 23, 1996
    Date of Patent: December 28, 1999
    Assignee: North Carolina State University
    Inventors: Mark A. Conkling, Charles H. Opperman, Gregoria N. Acedo, Wen Song