Abstract: Toll Like Receptor 3 (TLR3) antibody antagonists, polynucleotides encoding TLR3 antibody antagonists or fragments thereof, and methods of making and using the foregoing are disclosed.

Abstract: The present invention includes computerized method and apparatus for user interactivity with a network application executing on a server. The method and apparatus includes receiving, via a wireless network, an event message from a mobile device, the event message representing an input from a user interface on the mobile device where the user interface is executing based on a mobile application. The method and apparatus further includes generating data values based on the input in the event message and information relating to the mobile device. Moreover, the method and apparatus includes sending an update message to the mobile device based on the data values for updating a display of the mobile device.

Abstract: An anti-IL-23 antibody, including isolated nucleic acids that encode at least one anti-IL-23 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.

Abstract: Toll Like Receptor 3 (TLR3) antibody antagonists, polynucleotides encoding TLR3 antibody antagonists or fragments thereof, and methods of making and using the foregoing are disclosed.

Abstract: An intake assembly for a compressor providing compressed air to an internal combustion engine core, including an air conduit having at least one heat exchanger extending thereacross, an intake plenum for the compressor, a first intake conduit connected to the air conduit upstream of the heat exchanger(s), a second intake conduit connected to the air conduit downstream of the heat exchanger(s), and a selector valve configurable between a first configuration to allow a fluid communication between the intake plenum and the air conduit through the first intake conduit and a second configuration to prevent the fluid communication through the first intake conduit. Fluid communication between the intake plenum and the air conduit through the second intake conduit is allowed at least when the selector valve is in the second configuration. An engine assembly and method of supplying air to a compressor are also discussed.

Abstract: A compound engine assembly including a compressor, an engine core including at least one rotary internal combustion engine and having an inlet in fluid communication with an outlet of the compressor, a turbine section having an inlet in fluid communication with an outlet of the engine core and configured to compound power with the engine core, and an air conduit having at least one heat exchanger extending thereacross. An outer wall of the air conduit has a plurality of openings defined therethrough downstream of the heat exchanger(s), each selectively closable by a pivotable flap movable between a retracted position where the opening is obstructed and an extended position away from the opening. Each opening defines a fluid communication between the air conduit and the ambient air when the respective flap is in the extended position. A method of directing flow through a compound engine assembly is also discussed.

Abstract: A compound engine assembly including an air conduit having an inlet in fluid communication with ambient air around the compound engine assembly, a compressor having an inlet in fluid communication with the air conduit, an engine core including at least one rotary internal combustion engine and having an inlet in fluid communication with an outlet of the compressor, a turbine section having an inlet in fluid communication with an outlet of the engine core and configured to compound power with the engine core; and at least one heat exchanger in fluid communication with the air conduit, each heat exchanger configured to circulate a fluid of the engine assembly in heat exchange relationship with an airflow from the air conduit circulating therethrough. A method of supplying air to a compound engine assembly is also discussed.

Abstract: A human anti-IL-23p19 antibody, including isolated nucleic acids that encode at least one anti-IL-23p19 antibody, vectors, host cells, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.

Abstract: The present invention includes computerized method and apparatus for user interactivity with a network application executing on a server. The method and apparatus includes receiving, via a wireless network, an event message from a mobile device, the event message representing an input from a user interface on the mobile device where the user interface is executing based on a mobile application. The method and apparatus further includes generating data values based on the input in the event message and information relating to the mobile device. Moreover, the method and apparatus includes sending an update message to the mobile device based on the data values for updating a display of the mobile device.

Abstract: A human anti-IL-23p19 antibody, including isolated nucleic acids that encode at least one anti-IL-23p19 antibody, vectors, host cells, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.

Abstract: Toll Like Receptor 3 (TLR3) antibody antagonists, polynucleotides encoding TLR3 antibody antagonists or fragments thereof, and methods of making and using the foregoing are disclosed.

Abstract: An ejector comprises a primary nozzle having an annular wall forming part of an outer boundary of an exhaust portion of a primary flow path of a gas turbine engine. The annular wall has a downstream end defining a plurality of circumferentially distributed lobes. The ejector further comprises a secondary nozzle having an annular wall disposed about the primary nozzle, the primary nozzle and the secondary nozzle defining a secondary flow passage therebetween for channeling a secondary flow. The secondary nozzle defines a mixing zone downstream of an exit of the primary nozzle. A flow guide ring is mounted to the primary nozzle lobes. The ring has an aerodynamic surface extending from a leading edge to a trailing edge respectively disposed upstream and downstream of the exit of the primary nozzle. The aerodynamic surface of the ring is oriented to guide the high velocity primary flow into the mixing zone.

Abstract: Toll Like Receptor 3 (TLR3) antibody antagonists, polynucleotides encoding TLR3 antibody antagonists or fragments thereof, and methods of making and using the foregoing are disclosed.

Abstract: An anti-IL-23 antibody, including isolated nucleic acids that encode at least one anti-IL-23 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.

Abstract: An anti-IL-23 antibody, including isolated nucleic acids that encode at least one anti-IL-23 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.

Abstract: An anti-IL-23p19 antibody, including isolated nucleic acids that encode at least one anti-IL-23p19 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.

Abstract: An exhaust mixer for a gas turbine engine where each outer lobe has at the downstream end a circumferential offset in a direction corresponding to that of the swirl component of the flow entering the mixer. The mixer has a crest line having at least a downstream portion curved with respect with respect to a circumferential direction of the mixer and/or a center line at the downstream end tilted with respect to a radial line extending to the tip of the outer lobe to define the circumferential offset. A method of mixing a core flow and a bypass flow surrounding the core flow with an annular mixer is also provided.

Abstract: The present invention includes computerized method and apparatus for user interactivity with a network application executing on a server. The method and apparatus includes receiving, via a wireless network, an event message from a mobile device, the event message representing an input from a user interface on the mobile device where the user interface is executing based on a mobile application. The method and apparatus further includes generating data values based on the input in the event message and information relating to the mobile device. Moreover, the method and apparatus includes sending an update message to the mobile device based on the data values for updating a display of the mobile device.

Abstract: The present disclosure provides compounds of Formula I: or a pharmaceutically acceptable salt thereof, wherein R5, R6 and Z are as described herein. The disclosure also provides pharmaceutical compositions thereof; and methods for inhibiting DHFR activity; and methods for treating cell proliferative diseases, autoimmune disease, inflammatory disease or bacterial, fungal or parasitic infection by administering a compound of Formula I.

Abstract: Toll Like Receptor 3 (TLR3) antagonists, polynucleotides encoding TLR3 antagonists or fragments, and methods of making and using the foregoing are disclosed.