Abstract: The present invention relates to a novel method for analyzing nucleic acid sequences based on real-time detection of DNA polymerase-catalyzed incorporation of each of the four nucleotide bases, supplied individually and serially in a microfluidic system, to a reaction cell containing a template system comprising a DNA fragment of unknown sequence and an oligonucleotide primer. Incorporation of a nucleotide base into the template system can be detected by any of a variety of methods including but not limited to fluorescence and chemiluminescence detection. Alternatively, microcalorimetic detection of the heat generated by the incorporation of a nucleotide into the extending template system using thermopile, thermistor and refractive index measurements can be used to detect extension reactions.

Abstract: The present invention relates to a novel method for analyzing nucleic acid sequences based on real-time detection of DNA polymerase-catalyzed incorporation of each of the four nucleotide bases, supplied individually and serially in a microfluidic system, to a reaction cell containing a template system comprising a DNA fragment of unknown sequence and an oligonucleotide primer. Incorporation of a nucleotide base into the template system can be detected by any of a variety of methods including but not limited to fluorescence and chemiluminescence detection. Alternatively, microcalorimetic detection of the heat generated by the incorporation of a nucleotide into the extending template system using thermopile, thermistor and refractive index measurements can be used to detect extension reactions.

Abstract: An apparatus having flotation ballasts or tanks, a flotation platform having a frame, and on the frame and flotation platform, intake equipment, such as a screen, check valve and/or pump intake and a coupling for a discharge pipe. An embodiment comprises a plurality of substantially symmetrical flotation ballasts, each having a ballast tank forming a chamber with an internal bladder therein, or in lieu of the ballast chamber, at least one exposed bladder coupled to the frame and flotation platform. The method includes the steps of using an apparatus as herein described to ascend and descend intake equipment.

Abstract: An apparatus having flotation ballasts, a flotation platform and on the flotation platform, an intake equipment, such as a screen, check valve and/or pump intake and a coupling for a discharge pipe. In an embodiment of the present invention comprises, there are a plurality of substantially symmetrical flotation ballasts, each having a ballast chamber. The composition of the flotation ballast may be made of a material having a density appropriate for the fluid in which it is to be submerged. The method includes the steps of using an apparatus as herein described to ascend and descend intake equipment.

Abstract: The present invention relates to a novel method for analyzing nucleic acid sequences based on real-time detection of DNA polymerase-catalyzed incorporation of each of the four nucleotide bases, supplied individually and serially in a microfluidic system, to a reaction cell containing a template system comprising a DNA fragment of unknown sequence and an oligonucleotide primer. Incorporation of a nucleotide base into the template system can be detected by any of a variety of methods including but not limited to fluorescence and chemiluminescence detection. Alternatively, microcalorimetic detection of the heat generated by the incorporation of a nucleotide into the extending template system using thermopile, thermistor and refractive index measurements can be used to detect extension reactions.

Abstract: The present invention relates to a novel method for analyzing nucleic acid sequences based on real-time detection of DNA polymerase-catalyzed incorporation of each of the four nucleotide bases, supplied individually and serially in a microfluidic system, to a reaction cell containing a template system comprising a DNA fragment of unknown sequence and an oligonucleotide primer. Incorporation of a nucleotide base into the template system can be detected by any of a variety of methods including but not limited to fluorescence and chemiluminescence detection. Alternatively, microcalorimetic detection of the heat generated by the incorporation of a nucleotide into the extending template system using thermopile, thermistor and refractive index measurements can be used to detect extension reactions.

Abstract: The invention relates to a method for identifying the source of shed bioparticles and an apparatus that implements the method. The method involves collecting a sample of bioparticles from the environment, selecting from that sample the bioparticles most effective in identifying their source, and gathering data from those bioparticles to form bioparticle signatures. The bioparticle signatures are then processed into a multi-dimensional vector which is then compared to the multi-dimensional vector derived from a standard using a pattern recognition strategy that identifies the source. The apparatus has a particle collection device to collect the sample, a transfer device that selects information-rich bioparticles and a detector that restricts the movement of the information-rich bioparticles. The restricted movement is then translated into a bioparticle signature.

Abstract: The present invention relates to a novel method for analyzing nucleic acid sequences based on real-time detection of DNA polymerase-catalyzed incorporation of each of the four nucleotide bases, supplied individually and serially in a microfluidic system, to a reaction cell containing a template system comprising a DNA fragment of unknown sequence and an oligonucleotide primer. Incorporation of a nucleotide base into the template system can be detected by any of a variety of methods including but not limited to fluorescence and chemiluminescence detection. Alternatively, microcalorimetic detection of the heat generated by the incorporation of a nucleotide into the extending template system using thermopile, thermistor and refractive index measurements can be used to detect extension reactions.

Abstract: The present invention relates to a novel method for analyzing nucleic acid sequences based on real-time detection of DNA polymerase-catalyzed incorporation of each of the four nucleotide bases, supplied individually and serially in a microfluidic system, to a reaction cell containing a template system comprising a DNA fragment of unknown sequence and an oligonucleotide primer. Incorporation of a nucleotide base into the template system can be detected by any of a variety of methods including but not limited to fluorescence and chemiluminescence detection. Alternatively, microcalorimetic detection of the heat generated by the incorporation of a nucleotide into the extending template system using thermopile, thermistor and refractive index measurements can be used to detect extension reactions.

Abstract: The present invention relates to a novel method for analyzing nucleic acid sequences based on real-time detection of DNA polymerase-catalyzed incorporation of each of the four nucleotide bases, supplied individually and serially in a microfluidic system, to a reaction cell containing a template system comprising a DNA fragment of unknown sequence and an oligonucleotide primer. Incorporation of a nucleotide base into the template system can be detected by any of a variety of methods including but not limited to fluorescence and chemiluminescence detection. Alternatively, microcalorimetic detection of the heat generated by the incorporation of a nucleotide into the extending template system using thermopile, thermistor and refractive index measurements can be used to detect extension reactions.

Abstract: An apparatus having flotation ballasts, a flotation platform and on the flotation platform, an intake equipment, such as a screen, check valve and/or pump intake and a coupling for a discharge pipe. In an embodiment of the present invention comprises, there are a plurality of substantially symmetrical flotation ballasts, each having a ballast chamber. The composition of the flotation ballast may be made of a material having a density appropriate for the fluid in which it is to be submerged. The method includes the steps of using an apparatus as herein described to ascend and descend intake equipment.

Abstract: An apparatus having flotation ballasts, a flotation platform and on the flotation platform, an intake equipment, such as a screen, check valve and/or pump intake and a coupling for a discharge pipe. In an embodiment of the present invention comprises, there are a plurality of substantially symmetrical flotation ballasts, each having a ballast chamber. The composition of the flotation ballast may be made of a material having a density appropriate for the fluid in which it is to be submerged. The method includes the steps of using an apparatus as herein described to ascend and descend intake equipment.

Abstract: The present invention relates to a novel method for analyzing nucleic acid sequences based on real-time detection of DNA polymerase-catalyzed incorporation of each of the four nucleotide bases, supplied individually and serially in a microfluidic system, to a reaction cell containing a template system comprising a DNA fragment of unknown sequence and an oligonucleotide primer. Incorporation of a nucleotide base into the template system can be detected by any of a variety of methods including but not limited to fluorescence and chemiluminescence detection. Alternatively, microcalorimetic detection of the heat generated by the incorporation of a nucleotide into the extending template system using thermopile, thermistor and refractive index measurements can be used to detect extension reactions.

Abstract: A low-profile apparatus for converting water current into electricity. Fabric scoops are spaced along a continuous belt and, when submerged in a current of moving water, are pushed by the current thereby causing the continuous belt to move. The current pushes the fabric scoops downstream and then fold closed as the fabric scoops are rotated out of the water and travel back upstream. The moving continuous belt is used to turn an electric generator, which causes the apparatus to produce electrical energy. The apparatus includes one or more floats to support the continuous belt, electric generator, and other components of the apparatus. The apparatus can be moored or anchored in a variety of locations where there is moving water or currents. The apparatus maintains a low profile by using fabric scoops that collapse and fold flat when not submerged thereby reducing wind resistance and visible surface area above the waterline.

Abstract: The present invention relates to a novel method for analyzing nucleic acid sequences based on real-time detection of DNA polymerase-catalyzed incorporation of each of the four nucleotide bases, supplied individually and serially in a microfluidic system, to a reaction cell containing a template system comprising a DNA fragment of unknown sequence and an oligonucleotide primer. Incorporation of a nucleotide base into the template system can be detected by any of a variety of methods including but not limited to fluorescence and chemiluminescence detection. Alternatively, microcalorimetic detection of the heat generated by the incorporation of a nucleotide into the extending template system using thermopile, thermistor and refractive index measurements can be used to detect extension reactions.

Abstract: An apparatus having flotation ballasts, a flotation platform and on the flotation platform, an intake equipment, such as a screen, check valve and/or pump intake and a coupling for a discharge pipe. In an embodiment of the present invention comprises, there are a plurality of substantially symmetrical flotation ballasts, each having a ballast chamber. The composition of the flotation ballast may be made of a material having a density appropriate for the fluid in which it is to be submerged. The method includes the steps of using an apparatus as herein described to ascend and descend intake equipment.

Abstract: The present invention relates to a novel method for analyzing nucleic acid sequences based on real-time detection of DNA poly-merase-catalyzed incorporation of each of the four nucleotide bases, supplied individually and serially in a microfluidic system, to a reaction cell containing a template system comprising a DNA fragment of unknown sequence and an oligonucleotide primer. Incorporation of a nucleotide base into the template system can be detected by any of a variety of methods including but not limited to fluorescence and chemiluminescence detection. Alternatively, microcalorimetic detection of the heat generated by the incorporation of a nucleotide into the extending template system using thermopile, thermistor and refractive index measurements can be used to detect extension reactions.

Abstract: The present invention discloses the use of fetuin and fetuin producing agents in methods and compositions for treating burn injuries in animals.

Abstract: Disclosed are compositions and methods for producing movement of liquid across surfaces.

Abstract: A low-profile apparatus for converting water current into electricity. Fabric scoops are spaced along a continuous belt and, when submerged in a current of moving water, are pushed by the current thereby causing the continuous belt to move. The current pushes the fabric scoops downstream and then fold closed as the fabric scoops are rotated out of the water and travel back upstream. The moving continuous belt is used to turn an electric generator, which causes the apparatus to produce electrical energy. The apparatus includes one or more floats to support the continuous belt, electric generator, and other components of the apparatus. The apparatus can be moored or anchored in a variety of locations where there is moving water or currents. The apparatus maintains a low profile by using fabric scoops that collapse and fold flat when not submerged thereby reducing wind resistance and visible surface area above the waterline.