Patents by Inventor Mark A. Rogers

Mark A. Rogers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • [1,2,3]triazolo[4,5-D]pyrimidine derivatives
    Patent number: 9056866
    Abstract: The invention relates to a compound of formula (I) wherein A, R1 and R2 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.
    Type: Grant
    Filed: April 11, 2014
    Date of Patent: June 16, 2015
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Jean-Michel Adam, Caterina Bissantz, Uwe Grether, Atsushi Kimbara, Matthias Nettekoven, Stephan Roever, Mark Rogers-Evans
  • NOVEL ADAMANTYL DERIVATIVES AS CANNABINOID RECEPTOR 2 AGONISTS
    Publication number: 20150111886
    Abstract: The invention relates to a compound of formula (I) wherein A1, R1 and R2 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.
    Type: Application
    Filed: December 22, 2014
    Publication date: April 23, 2015
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Atsushi Kimbara, Uwe Grether, Matthias Nettekoven, Bernd Puellmann, Mark Rogers-Evans, Tanja Schulz-Gasch
  • LINKING OF CONTENT BETWEEN INSTALLATIONS OF A CONTENT MANAGEMENT SYSTEM
    Publication number: 20150100548
    Abstract: Content maintained in a first repository of a first installation (which can optionally be an on-premise installation) of a content management system, as well as metadata associated with the content, can be shared via an approach in which content items maintained in the first repository are synchronized with a copy of the content items maintained in a second repository of a second installation (which can optionally be a cloud-based installation). The first installation can be optionally firewall protected. The copy of the content items can be accessed by collaborative users both within and external to a firewall. Related systems, methods, products, etc. are described.
    Type: Application
    Filed: January 31, 2014
    Publication date: April 9, 2015
    Applicant: Alfresco Software, Inc.
    Inventors: Neil Mc Erlean, Tuna Aksoy, Nick Burch, Michael Farman, Paul Holmes-Higgin, John Newton, Brian Remmington, Mark Rogers, Jan Vonka, David Webster
  • HYBRID SYNCHRONIZATION BETWEEN CLOUD AND ON-PREMISE SYSTEMS IN A CONTENT MANAGEMENT SYSTEM
    Publication number: 20150101021
    Abstract: Content maintained in a first repository of a first installation (which can optionally be an on-premise installation) of a content management system, as well as metadata associated with the content, can be shared via an approach in which content items maintained in the first repository are synchronized with a copy of the content items maintained in a second repository of a second installation (which can optionally be a cloud-based installation). The first installation can be optionally firewall protected. The copy of the content items can be accessed by collaborative users both within and external to a firewall. Related systems, methods, products, etc. are described.
    Type: Application
    Filed: January 31, 2014
    Publication date: April 9, 2015
    Applicant: Alfresco Software, Inc.
    Inventors: Neil Mc Erlean, Tuna Aksoy, Nick Burch, Michael Farman, Paul Holmes-Higgin, John Newton, Brian Remmington, Mark Rogers, Jan Vonka, David Webster
  • APPARATUSES AND METHODS FOR SECURING DEEP BRAIN STIMULATION LEADS
    Publication number: 20150039063
    Abstract: Various examples are provided for securing deep brain stimulation (DBS) leads. In one example, among others, a DBS cap for securing a DBS lead includes a base ring adapted to be mounted within a counterbore opening formed in the skull, a lead securing element that mounts to the base ring, and a top cover that mounts to the base ring. In another example, a method for securing a DBS lead includes forming a counterbore opening in the skull, securing a DBS cap within the counterbore opening, passing a DBS lead through the DBS cap and the counterbore opening and positioning a tip of the lead in brain tissue, and securing the DBS lead to the DBS cap using an adhesive. The skull opening includes a lower bore, a concentric upper bore, and a step positioned at the interface of the upper and lower bores.
    Type: Application
    Filed: July 31, 2014
    Publication date: February 5, 2015
    Inventors: Michael Scott Okun, Kelly D. Foote, Mark Roger Davidson
  • 1,4,5,6-TETRAHYDRO-PYRIMIDIN-2-YLAMINE COMPOUNDS
    Publication number: 20140336208
    Abstract: This invention relates to compounds of the formula wherein R1 to R9 are as described below, or to pharmaceutically acceptable salts thereof. These compounds are BACE2 inhibitors and can be used as medicaments for the therapeutic and/or prophylactic treatment of diseases such as diabetes, particularly type 2 diabetes, and other metabolic disorders.
    Type: Application
    Filed: July 9, 2014
    Publication date: November 13, 2014
    Inventors: David Banner, Emanuele Gabellieri, Wolfgang Guba, Hans Hilpert, Benoit Hornsperger, Roland Humm, Harald Mauser, Alexander V. Mayweg, Robert Narquizian, Emmanuel Pinard, Mark Rogers-Evans, Thomas Woltering, Wolfgang Wostl
  • LAYERED AUDIO CODING AND TRANSMISSION
    Publication number: 20140303984
    Abstract: Embodiments of systems and methods are described for generating layered audio such that computing devices can request a variable amount of data based on criteria such as their available bandwidth, device capability, or user selection. A base layer and one or more enhancement layers that incrementally enhance the previous layers may be generated. A computing device may retrieve the base layer and/or one or more enhancement layers, adjusting, in real-time or near real-time, which layers are retrieved based on fluctuations in the available bandwidth among other possible criteria.
    Type: Application
    Filed: April 4, 2014
    Publication date: October 9, 2014
    Applicant: DTS, Inc.
    Inventors: Mark Rogers Johnson, Phillip L. Maness
  • LAYERED AUDIO RECONSTRUCTION SYSTEM
    Publication number: 20140303762
    Abstract: A computing device may receive or otherwise access a base audio layer and one or more enhancement audio layers. The computing device can reconstruct the retrieved base layer and/or enhancement layers into a single data stream or audio file. The local computing device may process audio frames in a highest enhancement layer retrieved in which the data can be validated (or a lower layer if the data in audio frames in the enhancement layer(s) cannot be validated) and build a stream or audio file based on the audio frames in that layer.
    Type: Application
    Filed: April 4, 2014
    Publication date: October 9, 2014
    Applicant: DTS, Inc.
    Inventors: Mark Rogers Johnson, Phillip L. Maness
  • NOVEL [1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE DERIVATIVES
    Publication number: 20140288046
    Abstract: The invention relates to a compound of formula (I) wherein A, R1 and R2 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.
    Type: Application
    Filed: April 11, 2014
    Publication date: September 25, 2014
    Applicant: HOFFMANN-LA ROCHE INC.
    Inventors: Jean-Michel Adam, Caterina Bissantz, Uwe Grether, Atsushi Kimbara, Matthias Nettekoven, Stephan Roever, Mark Rogers-Evans
  • 1,4,5,6-tetrahydro-pyrimidin-2-ylamine compounds
    Patent number: 8815881
    Abstract: This invention relates to compounds of the formula wherein R1 to R9 are as described below, or to pharmaceutically acceptable salts thereof. These compounds are BACE2 inhibitors and can be used as medicaments for the therapeutic and/or prophylactic treatment of diseases such as diabetes, particularly type 2 diabetes, and other metabolic disorders.
    Type: Grant
    Filed: August 3, 2011
    Date of Patent: August 26, 2014
    Assignees: Hoffmann-La Roche Inc., Siena Biotech S.p.A.
    Inventors: David Banner, Emanuele Gabellieri, Wolfgang Guba, Hans Hilpert, Benoit Hornsperger, Roland Humm, Harald Mauser, Alexander V. Mayweg, Robert Narquizian, Emmanuel Pinard, Mark Rogers-Evans, Thomas Woltering, Wolfgang Wostl
  • Systems and Methods for Detecting the Presence of Anomalous Material within Tissue
    Publication number: 20140219535
    Abstract: In one embodiment, the presence of anomalous material within tissue is detected by scanning a patient using magnetic resonance imaging (MRI) to obtain MRI data, identifying individual voxels of the MRI data, identifying multiple parameters of each voxel, and determining as to each voxel based upon the identified parameters the likelihood of tissue represented by the voxel containing anomalous material.
    Type: Application
    Filed: September 6, 2012
    Publication date: August 7, 2014
    Inventors: Yunmei Chen, Mark Rogers Davidson, Keith David White, Jon Paul Dobson
  • 1,3-oxazines as BACE 1 and/or BACE2 inhibitors
    Patent number: 8785436
    Abstract: The present invention provides compounds of formula I having BACE1 and/or BACE2 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease and type 2 diabetes.
    Type: Grant
    Filed: May 9, 2012
    Date of Patent: July 22, 2014
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Hans Hilpert, Robert Narquizian, Emmanuel Pinard, Alessandra Polara, Mark Rogers-Evans, Thomas Woltering, Wolfgang Wostl
  • Pyrrolidin-3yl-methylamine quinoxaline derivatives
    Patent number: 8748430
    Abstract: The present invention is concerned with novel sulfonamides of formula I wherein R1, R2, Ar, Hetaryl, m and n are as described in the description and claims. The compounds are orexin receptor antagonists, useful in the treatment of disorders, in which orexin pathways are involved.
    Type: Grant
    Filed: May 23, 2012
    Date of Patent: June 10, 2014
    Assignee: Hoffmann-La Roche Inc
    Inventors: Henner Knust, Matthias Nettekoven, Emmanuel Pinard, Olivier Roche, Mark Rogers-Evans
  • 1,4-oxazepines as BACE1 and/or BACE2 inhibitors
    Patent number: 8748418
    Abstract: The present invention relates to 1,4-Oxazepines of formula I having BACE1 and/or BACE2 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease and type 2 diabetes.
    Type: Grant
    Filed: March 9, 2012
    Date of Patent: June 10, 2014
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Emanuele Gabellieri, Wolfgang Guba, Hans Hilpert, Harald Mauser, Alexander V. Mayweg, Mark Rogers-Evans, Didier Rombach, Andrew Thomas, Thomas Woltering, Wolfgang Wostl
  • ENHANCED RE-HOSTING CAPABILITY FOR LEGACY HARDWARE AND SOFTWARE
    Publication number: 20140152103
    Abstract: Embodiments of the invention are directed toward systems and methods that execute legacy semiconductor applications using a non-legacy controller. In some embodiments a hardware abstraction layer and/or an emulator can be used to provide communication between a non-legacy operating system and legacy components including legacy applications. In some embodiments various methods and/or devices can be used to emulate and/or translate communications between legacy and non-legacy components.
    Type: Application
    Filed: February 20, 2013
    Publication date: June 5, 2014
    Applicant: APPLIED MATERIALS, INC.
    Inventors: Ronald Vern Schauer, Mark Roger Covington, Suresh Kumaraswami, Amitabh Puri
  • [1,2,3]triazolo[4,5-D]pyrimidine derivatives
    Patent number: 8741906
    Abstract: The invention relates to a compound of formula (I) wherein A, R1 and R2 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.
    Type: Grant
    Filed: November 6, 2012
    Date of Patent: June 3, 2014
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Jean-Michel Adam, Caterina Bissantz, Uwe Grether, Atsushi Kimbara, Matthias Nettekoven, Stephan Roever, Mark Rogers-Evans
  • Apparatus and methods of flow testing formation zones
    Patent number: 8720554
    Abstract: A method of flow testing multiple zones in a wellbore includes lowering a tool string into the wellbore. The tool string includes an inflatable packer or plug and an electric pump. The method further includes operating the pump, thereby inflating the packer or plug and isolating a first zone from one or more other zones; monitoring flow from the first zone; deflating the packer or plug; moving the tool string in the wellbore; and operating the pump, thereby inflating the packer or plug and isolating a second zone from one or more other zones; and monitoring flow from the second zone. The zones are monitored in one trip.
    Type: Grant
    Filed: October 11, 2012
    Date of Patent: May 13, 2014
    Assignee: Weatherford/Lamb, Inc.
    Inventors: Timothy Dale Clapp, Robert Murphy, Paul James Wilson, Mark Rogers
  • SYNCHRONIZED STREAM PACKING
    Publication number: 20140126886
    Abstract: There are provided methods and apparatus for synchronized stream packing of packets that differ contextually between A/V streams in a parallel presentation. A method includes the step of identifying sub-picture/subtitle packets and/or audio packets having arrival timestamps and/or presentation timestamps that match an arrival timestamp and/or a presentation timestamp, respectively, of video packets. The method also includes the step of packing a Video Object Unit (VOBU) and/or a Transport Stream (TS) with the identified sub-picture/subtitle and audio packets and the video packets having the matching timestamps.
    Type: Application
    Filed: January 15, 2014
    Publication date: May 8, 2014
    Applicant: THOMSON LINCENSING
    Inventors: Mark Rogers JOHNSON, Ralf OSTERMANN, Joseph Sanderson RICE
  • SYNCHRONIZED STREAM PACKING
    Publication number: 20140126885
    Abstract: There are provided methods and apparatus for synchronized stream packing of packets that differ contextually between A/V streams in a parallel presentation. A method includes the step of identifying sub-picture/subtitle packets and/or audio packets having arrival timestamps and/or presentation timestamps that match an arrival timestamp and/or a presentation timestamp, respectively, of video packets. The method also includes the step of packing a Video Object Unit (VOBU) and/or a Transport Stream (TS) with the identified sub-picture/subtitle and audio packets and the video packets having the matching timestamps.
    Type: Application
    Filed: January 15, 2014
    Publication date: May 8, 2014
    Applicant: THOMSON LICENSING
    Inventors: Mark Rogers JOHNSON, Ralf OSTERMANN, Joseph Sanderson RICE
  • Piperidine sulphonamide derivatives
    Patent number: 8691846
    Abstract: The present invention relates to piperidine sulphonamide derivatives of formula wherein Ar1, Ar2, R1, R2, m and n are as defined in the description and claims, or pharmaceutically suitable acid addition salts thereof. The compounds of formula I are orexin receptor antagonists and the related compounds can be useful in the treatment of sleep apnea, narcolepsy, insomnia, parasomnia, jet lag syndrome, circadian rhythms disorder or sleep disorders associated with neurological diseases.
    Type: Grant
    Filed: April 2, 2013
    Date of Patent: April 8, 2014
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Henner Knust, Matthias Nettekoven, Emmanuel Pinard, Olivier Roche, Mark Rogers-Evans