Abstract: Dimensions of a surface feature are determined by capturing an image of the surface feature and determining a scale associated with the image. Structured light may be projected onto the surface, such that the position of structured light in the captured image allows determination of scale. A non-planar surface may be unwrapped. The surface may alternatively be projected into a plane to correct for the scene being tilted with respect to the camera axis. A border of the surface feature may be input manually by a user. An apparatus and system for implementing the method are also disclosed.

Abstract: Provided are polypeptides and compositions comprising novel HSP-binding peptides. Such polypeptides and compositions are particularly useful as immunotherapeutics (e.g., cancer vaccines). Also provided are methods of inducing a cellular immune response using such polypeptides and compositions, methods of treating a disease using such polypeptides and compositions, kits comprising such polypeptides and compositions, and methods of making such compositions.

Abstract: The instant disclosure provides antibodies that specifically bind to CTLA-4 (e.g., human CTLA-4) and antagonize CTLA-4 function. Also provided are pharmaceutical compositions comprising these antibodies, nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodies, and methods of treating a subject using these antibodies.

Abstract: An upper of an article of footwear comprises a plurality of stretch zones each having a respective stretching capability. Suitable example stretch zones may include four-way stretch zones, two-way stretch zones, and/or lock-out zones. In some examples, an upper having a plurality of stretch zones comprises a single continuous piece of material configured to have regions of different stretching capability. The single piece of material may comprise a layered material having two stretchable outer layers, wherein a plurality of stretch zones of the piece of material are defined by corresponding intermediate layers disposed at selected locations between the outer layers. Examples of intermediate layers providing two-way stretch, four-way stretch, and little or no stretch are disclosed.

Abstract: A dual-layered midsole for footwear includes an internal midsole layer and an external midsole layer, which are coupled to and separated by a Strobel board. The internal midsole layer may compress and expand with the movement of a wearer of an article of footwear including the dual-layered midsole, while the external midsole may provide stability and cushion for the wearer. Materials selected for the internal and external midsole layers may provide tuned viscoelastic properties to different areas of the midsole as a function of midsole layer thickness at each sole area.

Abstract: The instant disclosure provides antibodies that specifically bind to CTLA-4 (e.g., human CTLA-4) and antagonize CTLA-4 function. Also provided are pharmaceutical compositions comprising these antibodies, nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodies, and methods of treating a subject using these antibodies.

Abstract: The instant disclosure provides antibodies that specifically bind to CD137 (e.g., human CD137) and increases CD137 function. Also provided are pharmaceutical compositions comprising these antibodies, nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodies, and methods of treating a subject using these antibodies.

Abstract: The instant disclosure provides antibodies that specifically bind to CTLA-4 (e.g., human CTLA-4) and antagonize CTLA-4 function. Also provided are pharmaceutical compositions comprising these antibodies, nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodies, and methods of treating a subject using these antibodies.

Abstract: The instant disclosure provides antibodies that specifically bind to CTLA-4 (e.g., human CTLA-4) and antagonize CTLA-4 function. Also provided are pharmaceutical compositions comprising these antibodies, nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodies, and methods of treating a subject using these antibodies.

Abstract: Dimensions of a surface feature are determined by capturing an image of the surface feature and determining a scale associated with the image. Structured light may be projected onto the surface, such that the position of structured light in the captured image allows determination of scale. A non-planar surface may be unwrapped. The surface may alternatively be projected into a plane to correct for the scene being tilted with respect to the camera axis. A border of the surface feature may be input manually by a user. An apparatus and system for implementing the method are also disclosed.

Abstract: A sports electronic training system, and applications thereof, are disclosed. In an embodiment, a portable performance monitoring system for monitoring an individual's performance during a physical activity includes a motion monitor adapted to be physically coupled to the individual during the activity and a portable electronic processing device adapted to be physically coupled to the individual during the activity. The portable electronic processing device includes a wireless personal-area network transceiver adapted for wireless communication with the motion monitor, a memory adapted to store workout program data, a processor adapted to determine performance information for the individual, and an output adapted to provide feedback to the individual based on the performance information and the workout program data.

Abstract: A facility for procuring and analyzing information about an anatomical surface feature from a caregiver that is usable to generate an assessment of the surface feature is described. The facility displays information about the surface feature used in the assessment of the surface feature. The facility obtains user input and/or data generated by an image capture device to assess the surface feature or update an existing assessment of the surface feature.

Abstract: A multi-touch sensor panel is disclosed that can include a glass subassembly having a plurality of column traces of substantially transparent conductive material that can be formed on the back side, wherein the glass subassembly can also act as a cover that can be touched on the front side. Row traces of the same or different substantially transparent conductive material can then be located near the column traces, and a layer of dielectric material can be coupled between the column traces and the row traces. The row and column traces can be oriented to cross over each other at crossover locations separated by the dielectric material, and the crossover locations can form mutual capacitance sensors for detecting one or more touches on the front side of the glass subassembly.

Abstract: Location-aware fitness monitoring program products, systems, and methods, and applications thereof, are disclosed. In an embodiment, a method for providing information about an athletic activity includes the steps of displaying to a user via a computer performance parameter information regarding an individual's performance during the athletic activity as a function of time, and displaying to the user via the computer the title of a music track that was played for the individual by a portable fitness monitoring device during the athletic activity, wherein the display of the title of the music track occurs in response to the user specifying via the computer a particular point in time during the athletic activity.

Abstract: A multi-touch sensor panel is disclosed that can be produced by forming a plurality of first traces of substantially transparent conductive material on a first substrate, forming a plurality of second traces of the substantially transparent material, and creating a fluid-tight gap between the plurality of first traces and the plurality of second traces. The fluid-tight gap can then be filled with a fluid having substantially no bubbles and an optical index similar to the optical index of the first and second traces to make the gap and the first and second traces substantially transparent. The second and first traces can be oriented to cross over each other at crossover locations separated by the fluid, the crossover locations forming mutual capacitance sensors for detecting touches.

Abstract: Portable fitness monitoring methods are disclosed. In an embodiment, a portable fitness monitoring method includes a method for providing audible output to a user during an athletic activity using a portable fitness monitoring device. The method includes the steps of receiving an audio feedback file package that includes a first audio feedback file, updating the audio feedback file package, and processing the updated audio feedback file package to provide audible output to the user through an audio output device during the athletic activity.

Abstract: Provided are antibodies that specifically bind to CTLA-4 and/or PD-1 and antagonize CTLA-4 and/or PD-1 function. Also provided are pharmaceutical compositions and kits comprising these antibodies, nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodies, and methods of treating a subject using these antibodies either alone or in combination.

Abstract: Provided are polypeptides and compositions comprising novel HSP-binding peptides. Such polypeptides and compositions are particularly useful as immunotherapeutics (e.g., cancer vaccines). Also provided are methods of inducing a cellular immune response using such polypeptides and compositions, methods of treating a disease using such polypeptides and compositions, kits comprising such polypeptides and compositions, and methods of making such compositions.

Abstract: Location-aware fitness monitoring program products, systems, and methods, and applications thereof, are disclosed. In an embodiment, a method for providing information about an athletic activity includes the steps of displaying to a user via a computer performance parameter information regarding an individual's performance during the athletic activity as a function of time, and displaying to the user via the computer the title of a music track that was played for the individual by a portable fitness monitoring device during the athletic activity, wherein the display of the title of the music track occurs in response to the user specifying via the computer a particular point in time during the athletic activity.

Abstract: A multi-touch sensor panel is disclosed that can include a glass subassembly having a plurality of column traces of substantially transparent conductive material that can be formed on the back side, wherein the glass subassembly can also act as a cover that can be touched on the front side. Row traces of the same or different substantially transparent conductive material can then be located near the column traces, and a layer of dielectric material can be coupled between the column traces and the row traces. The row and column traces can be oriented to cross over each other at crossover locations separated by the dielectric material, and the crossover locations can form mutual capacitance sensors for detecting one or more touches on the front side of the glass subassembly.