Abstract: An iontophoresis device (10) includes a membrane applied to said skin having a drug delivery aperture, a solvent delivery aperture and a vent aperture for applying a vacuum between the membrane and skin. A drug cartridge defines a drug containing chamber in communication with the drug delivery aperture and a drug air chamber separated by a first flexible membrane. A solvent cartridge defines a solvent containing chamber and a solvent air chamber separated by a second flexible membrane. An electrode is positioned between the membrane and the skin and surrounds the drug delivery aperture and the solvent delivery aperture. A drug cartridge may also include two separate chambers, one containing a lyophilized agent, the other containing a solvent. The solvent and the agent remain separate until mixed during operation of the device.

Abstract: Examples provided herein involve a playback history for media items played by playback zones of a media playback system. An example implementation involves a mobile device querying, via a network interface, a database hosted by one or more servers for a particular portion of a playback history stored in the database, the particular portion of the playback history corresponding to media items played by the media playback system during the particular time period. The mobile device displays graphical representations of the particular media items played during the particular time period by the media playback system. The mobile device may receive input data selecting one or more particular media items played during the particular time period by the media playback system and add the selected one or more particular media items to a queue.

Abstract: This invention, in embodiments, relates to a roofing drip edge device that includes a drip edge comprising (i) an upper drip edge that is configured to be installed along an edge of a roofing surface, and (ii) a lower drip edge that is approximately at a right angle to the upper drip edge, a flashing strip member that is secured to the upper drip edge of the drip edge, such that a portion of the flashing strip member overhangs a first side edge of the drip edge, and a connecting member that is secured to the drip edge, such that a portion of the connecting member overhangs a second side edge of the drip edge. This invention, in embodiments, further relates to a method of installing a roofing drip edge device.

Abstract: The present disclosure provides methods for the acute treatment of migraine with or without aura, comprising the administration of ubrogepant. In particular, the present disclosure provides methods for the acute treatment of migraine in patients having hepatic impairment; in patients with renal impairment; and in patients concurrently taking CYP3A4 modulators or BCRP and/or P-gp only inhibitors.

Abstract: Methods and systems of managing dynamic response to wind in a solar tracker system are provided. The method includes determining a wind speed, comparing the wind speed to a predetermined threshold value to determine if the wind speed equals or exceeds the predetermined threshold, positioning a windward most solar tracker to a predetermined angle based on the comparing, and positioning a leeward most solar tracker to the predetermined angle based on the comparing. The solar trackers are positioned at the predetermined angle at a predetermined interval starting at the windward most solar tracker and the remaining solar trackers remain in a normal operating condition.

Abstract: A molded container of plastic material. The molded container including a neck finish defining an opening into the molded container, a body extending from the neck finish and including a shoulder adjacent the neck finish, a base defining a closed end of the container, and a sidewall extending between the shoulder and the base. Formed on a surface of the container and being defined by the plastic material forming the container are a series of raised dots defining a tactile writing feature.

Abstract: An impact tool includes a housing having a motor housing portion and an impact housing portion. The impact housing portion has a front end defining a front end plane. An electric motor is supported in the motor housing, a battery pack is supported by the housing for providing power to the motor, and a drive assembly is supported by the impact housing portion. The drive assembly includes an anvil extending from the front end of the front housing portion with an end defining an anvil end plane. The drive assembly also includes a hammer rotationally and axially movable relative to the anvil for imparting the consecutive rotational impacts upon the anvil, and a spring for biasing the hammer in an axial direction toward the anvil. A distance between the front end plane and the anvil end plane is greater than or equal to 6 inches.

Abstract: A system and system for personal pathogen status verifying allows an entity to control access to an area of congregation (AOC) at one or more points of entry (POE) is a configurable manner. In one embodiment, the system may be used for the SARS-CoV-2 virus, but may be similarly used for other pathogens.

Abstract: Flange for a vacuum apparatus comprises a housing to be connected to the vacuum apparatus defining an opening wherein the opening has rectangular narrow shape. The flange further comprises a metal seal arranged around the opening to create a vacuum tight seal.

Abstract: A computing network comprising a computing service provider and an edge computing network is managed. A trusted device establishes a root of trust at the edge computing network via a trusted component on the trusted device. In response to receiving a first indication of a disconnection or degradation of communications between the computing service provider and the edge computing network, the edge computing network initiates an autonomous mode at the edge computing network. While the edge computing network is operating in the autonomous mode, the trusted device detects new devices that are attempting to access computing resources in the edge computing network. The trusted device stores data pertaining to new devices that were not authorized to access the computing resources in the edge computing network.

Abstract: The present disclosure provides methods for the acute treatment of migraine with or without aura, comprising the administration of ubrogepant. In particular, the present disclosure provides methods for the acute treatment of migraine in patients having hepatic impairment; in patients with renal impairment; and in patients concurrently taking CYP3A4 modulators or BCRP and/or P-gp only inhibitors.

Abstract: Connectors and methods for contactless transfer of fluid between containers are disclosed. According to an aspect, a connector includes a body that defines a first end, a second end, and a passageway that extends between the first end and the second end, wherein the first end and second end are configured to attach to a first container and a second container, respectively. The passageway provides a pathway between the first and second containers when the first and second containers are attached to the first and second ends, respectively. Further, the connector includes an opener configured to engage and open the first container for release of a fluid from within the first container through the passageway and into the second container when the first and second containers are attached to the first and second ends, respectively.

Abstract: This invention, in embodiments, relates to a roofing system that includes a roof deck, a plurality of tapered insulation panels applied onto the roof deck, at least one non-tapered insulation panel applied onto the plurality of tapered insulation panels, and a membrane layer applied onto the at least one non-tapered insulation panel. This invention, in embodiments, further relates to a roof assembly kit that includes a plurality of tapered insulation panels and instructions for installation, as well as a method of installing such a roofing system.

Abstract: The present disclosure relates to systems, methods, and computer readable media for facilitating placement of network functions based on a network slice profile that is received and based on internal knowledge of a cloud computing system having network resources thereon. The systems described herein involve tagging the network resources with various characteristics, generating resource management profiles including instructions that may be used to supplement information from the slice profile(s), and matching an incoming slice profile with a resource management profile. The systems described herein facilitate rolling out a deployment of network functions on the network resources in accordance with information from the resource management profile in a way that optimizes resources and allows automated placement of network functions based on a received network slice.

Abstract: The present disclosure relates to systems, methods, and computer readable media for receiving and processing a request to deploy network functions across one or more deployment areas of a telecommunications network. Systems described herein process a request by applying a hierarchical configuration model including a hierarchy of configuration management instructions that can be applied to a request that complies with a format of the hierarchical configuration model. Features described herein facilitate deployment of unique configuration instructions across multiple network functions and across multiple deployment areas based on a single request and without further user interaction with respect to each of multiple network functions.

Abstract: The present disclosure relates to a network function configuration system that efficiently, accurately, and flexibly manages network function configurations in a cloud computing system for a 5G (and beyond) telecommunications network. For example, the network function configuration system utilizes configuration snapshots to perform batches of configuration updates atomically to network functions of a mobile packet core that is implemented in a cloud computing system. To illustrate, in a cloud computing system (such as a core network), network functions run in a current state. To modify the configuration snapshot to a desired state, numerous network function configuration changes must often be applied.

Abstract: This invention relates to an oligonucleotide comprising one or more 2?-modified nucleosides, wherein the 2?-position of the nucleoside has a structure of formula (I). The invention also relates to a pharmaceutical composition comprising the oligonucleotide described herein and a method of reducing or inhibiting the expression of a target gene by administering to the subject a therapeutically effective amount of the oligonucleotide described herein.

Abstract: A medical device inspection scope may include a cylindrical outer layer having a diameter of less than 2 millimeters or even less than 1 millimeter, a cylindrical inner layer disposed concentrically within the outer layer, a circumferential space between the outer layer and the inner layer, and an inner lumen formed by the inner layer. The scope also includes multiple light transmitting fibers disposed in the circumferential space and a camera module disposed in the inner lumen. The light fibers may be designed to transmit illumination light and ultraviolet light. The scope may also optionally include a stiffening member.

Abstract: This invention, in embodiments, relates to a roofing drip edge device that includes a drip edge comprising (i) an upper drip edge that is configured to be installed along an edge of a roofing surface, and (ii) a lower drip edge that is approximately at a right angle to the upper drip edge, a flashing strip member that is secured to the upper drip edge of the drip edge, such that a portion of the flashing strip member overhangs a first side edge of the drip edge, and a connecting member that is secured to the drip edge, such that a portion of the connecting member overhangs a second side edge of the drip edge. This invention, in embodiments, further relates to a method of installing a roofing drip edge device.

Abstract: The present application provides an aft plate removal tool for servicing a combustor. The combustor includes an aft plate with a central passage and a number of tubes extending through the aft plate. The aft plate removal tool includes a central screw, a lower housing attached to the central screw, the lower housing including a number of spring loaded lower housing feet, and an upper housing attached to the center screw, the upper housing including a number of spring loaded upper housing feet. The aft plate removal tool is inserted through the central passage of the aft plate such that rotation of the upper housing advances the spring loaded upper housing feet against the aft plate until the spring loaded upper housing feet push the aft plate off of the tubes.