Patents by Inventor Mark Brown
Mark Brown has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12540576Abstract: Inner structure diffuser/OGV assemblies for gas turbine engines are disclosed herein. A gas turbine engine includes a compressor section, a combustion section, and a turbine section in a serial flow arrangement. The combustion section includes an outer casing and an inner structure assembly coupled to the outer casing. The inner structure assembly includes an outer radial support arm, an inner radial support arm, and a diffuser coupled between the outer radial support arm and the inner radial support arm. The outer radial support arm extends at least partially in an axially downstream direction from the diffuser, and the inner radial support arm extends at least partially in the axially downstream direction from the diffuser. The outer radial support arm defines an opening therethrough.Type: GrantFiled: September 26, 2024Date of Patent: February 3, 2026Assignee: General Electric CompanyInventors: Ajay Kumar Verma, Jeremy K. Payne, Adam Robert Kahn, Trevor James Hahm, Veera Venkata Amarnath Manem, Mohan Hanumappa Reddy, Mark Brown
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Patent number: 12490735Abstract: A rodent-proof barrier material comprising a settable carrier medium and a plurality of filaments dispersed within the settable carrier medium. Each filament of the plurality of filaments comprises a central curved portion and first and second end portions.Type: GrantFiled: November 12, 2021Date of Patent: December 9, 2025Assignee: Rentokil Initial 1927 PLCInventors: Gary Wingett, Mark Brown, Robert Shand
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Patent number: 12486126Abstract: A seal for a dock levelling system including a movable ramp arranged within a recess. The seal is for sealing a gap between a side of the movable ramp and a wall of the recess, and including a flexible strip formed of a flexible material, and on each longitudinal edge of the flexible strip, an attachment strip for attaching the flexible strip to the side of the movable ramp. The seal is arranged so that when the attachment strips are attached adjacently to each other to the side of the movable ramp, the material of the flexible strip between the attachment strips forms a closed loop extending out from the side of the movable ramp to the wall of the recess, to seal the gap between the side of the movable ramp and the wall of the recess.Type: GrantFiled: January 20, 2021Date of Patent: December 2, 2025Assignee: Rentokil Initial 1927 PLCInventors: Gary Wingett, Mark Brown, Robert Shand
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Patent number: 12459761Abstract: A seal for a dock levelling system including a movable hinged ramp arranged within a recess. The seal is for sealing a horizontal gap between the hinged end of the movable ramp and a wall of the recess, and includes a rod and a tube of flexible material surrounding the rod.Type: GrantFiled: January 20, 2021Date of Patent: November 4, 2025Assignee: Rentokil Initial 1927 PLCInventor: Mark Brown
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Publication number: 20250314122Abstract: A door seal for spanning a gap between a door and a surface adjacent to the edge of the door to prevent the passage of rodents is provided. The door seal is arranged to be mounted on an edge of the door. The door seal includes a flexible hollow cylinder formed of an elastomeric material, and a cylinder of knitted barrier material positioned inside the flexible hollow cylinder. The exterior surface of the cylinder of knitted barrier material is in contact with the interior surface of the flexible hollow cylinder.Type: ApplicationFiled: May 17, 2023Publication date: October 9, 2025Applicant: RENTOKIL INTIAL 1927 PLCInventors: Craig Jones, Mark Brown, Emma Chisholm, Nikki Dexter, Sam Plowman
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Patent number: 12410606Abstract: An expansion joint for providing a rodent-proof barrier. The expansion joint comprises an elongate core formed of a resiliently deformable material, and a flexible sheath of a barrier material covering at least a part of the elongate portion of the elongate core. The elongate portion of the elongate core is compressible in a direction perpendicular to a line between the first and second ends of the elongate core, the elongate core being arranged to be compressed and inserted into a gap between first and second building structures, and to expand after insertion into the gap so that the expansion joint is held in place within the gap by friction between the surface of the flexible sheath and the surfaces of the first and second building structures.Type: GrantFiled: September 13, 2021Date of Patent: September 9, 2025Assignee: RENTOKIL INITIAL 1927 PLCInventors: Mark Brown, Craig Alan Jones
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Patent number: 12371896Abstract: An expansion joint for providing a rodent-proof barrier. The expansion joint comprises an elongate core formed of a resiliently deformable material, and a flexible sheath of a barrier material covering at least a part of the elongate portion of the elongate core. The elongate portion of the elongate core is compressible in a direction perpendicular to a line between the first and second ends of the elongate core, the elongate core being arranged to be compressed and inserted into a gap between first and second building structures, and to expand after insertion into the gap so that the expansion joint is held in place within the gap by friction between the surface of the flexible sheath and the surfaces of the first and second building structures.Type: GrantFiled: September 13, 2021Date of Patent: July 29, 2025Assignee: RENTOKIL INITIAL 1927 PLCInventors: Mark Brown, Craig Alan Jones
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Publication number: 20250145951Abstract: Disclosed are media, supplements and methods for expanding mammalian lymphocytes or progenitors thereof, such as B cells, T cells, or NK cells. The disclosed media, supplements and methods may be used to expand mammalian lymphocytes or progenitors thereof plated as single cells, or at a clonal cell density. In some embodiments, the disclosed media, supplements and methods may also differentiate/activate the lymphocytes during expansion. The media, supplements and methods of this disclosure may be used in serum-free and feeder-free culture workflows.Type: ApplicationFiled: February 16, 2023Publication date: May 8, 2025Inventors: Hitesh ARORA, Mark BROWN
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Patent number: 12109081Abstract: A medical device inspection scope may include a cylindrical outer layer having a diameter of less than 2 millimeters or even less than 1 millimeter, a cylindrical inner layer disposed concentrically within the outer layer, a circumferential space between the outer layer and the inner layer, and an inner lumen formed by the inner layer. The scope also includes multiple light transmitting fibers disposed in the circumferential space and a camera module disposed in the inner lumen. The light fibers may be designed to transmit illumination light and ultraviolet light. The scope may also optionally include a stiffening member.Type: GrantFiled: March 12, 2019Date of Patent: October 8, 2024Assignee: Clarus Medical, LLCInventors: Scott Allen Sundet, Cindy Trosen Sundet, Randal Alan Gatzke, Mark Brown
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Publication number: 20240309101Abstract: The present disclosure provides antibody sequences found in antibodies that bind to human CD25. In particular, the present disclosure provides sequences of anti-human CD25 antibodies, which do not block the binding of CD25 to IL-2 or IL-2 signalling. Antibodies and antigen-binding portions thereof including such sequences can be used in pharmaceutical composition and methods of treatment, in particular for treating cancer.Type: ApplicationFiled: September 20, 2023Publication date: September 19, 2024Inventors: Anne Goubier, Beatriz Goyenechea Corzo, Josephine Salimu, Kevin Moulder, Pascal Merchiers, Mark Brown, Sergio Quezada, James Geoghegan, Bianka Prinz
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Publication number: 20240046375Abstract: Examples can include a system for video chat cycles within a social media application. An organizer platform can be used to design a schedule for the video chat cycles. This can include scheduled organizer content before, after, and between video chats. The organizer content can include graphics, video, and even live streams by the organizer.Type: ApplicationFiled: August 21, 2023Publication date: February 8, 2024Inventors: Jeff Emile, Mark Brown
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Publication number: 20240023538Abstract: A rodent-proof barrier material comprising a settable carrier medium and a plurality of filaments dispersed within the settable carrier medium. Each filament of the plurality of filaments comprises a central curved portion and first and second end portions.Type: ApplicationFiled: November 12, 2021Publication date: January 25, 2024Applicant: RENTOKIL INITIAL 1927 PLCInventors: Gary Wingett, Mark Brown, Robert Shand
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Publication number: 20230374779Abstract: An expansion joint for providing a rodent-proof barrier. The expansion joint comprises an elongate core formed of a resiliently deformable material, and a flexible sheath of a barrier material covering at least a part of the elongate portion of the elongate core. The elongate portion of the elongate core is compressible in a direction perpendicular to a line between the first and second ends of the elongate core, the elongate core being arranged to be compressed and inserted into a gap between first and second building structures, and to expand after insertion into the gap so that the expansion joint is held in place within the gap by friction between the surface of the flexible sheath and the surfaces of the first and second building structures.Type: ApplicationFiled: September 13, 2021Publication date: November 23, 2023Applicant: RENTOKIL INITIAL 1927 PLCInventors: Mark Brown, Craig Alan Jones
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Patent number: 11814434Abstract: The present disclosure provides antibody sequences found in antibodies that bind to human CD25, in particular an anti CD25-a-672 antibody which do not block the binding of CD25 to IL-2 or IL-2 signalling. The claimed antibody binds to the epitopes: PHATFKAMA YKEGTM (42-56) and YQCVQGYRALH (150-160) on CD25. Antibodies and antigen-binding portions thereof including such sequences can be used in pharmaceutical compositions and methods of treatment, in particular for treating cancer.Type: GrantFiled: March 13, 2019Date of Patent: November 14, 2023Assignees: Tusk Therapeutics Ltd., Cancer Research Technology LimitedInventors: Anne Goubier, Beatriz Goyenechea Corzo, Josephine Salimu, Kevin Moulder, Pascal Merchiers, Mark Brown, James Geoghegan, Bianka Prinz, Sergio Quezada
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Patent number: 11802161Abstract: The present disclosure provides antibody sequences found in antibodies that bind to human CD25, in particular an anti CD25-a-634 antibody which do not block the binding of CD25 to IL-2 or IL-2 signalling. Antibodies and antigen-binding portions thereof including such sequences can be used in pharmaceutical compositions and methods of treatment, in particular for treating cancer.Type: GrantFiled: March 13, 2019Date of Patent: October 31, 2023Assignees: Tusk Therapeutics Ltd., Cancer Research Technology LimitedInventors: Anne Goubier, Beatriz Goyenechea Corzo, Josephine Salimu, Kevin Moulder, Pascal Merchiers, Mark Brown, James Geoghegan, Bianka Prinz, Sergio Quezada
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Patent number: 11802160Abstract: The present disclosure provides antibody sequences found in antibodies that bind to human CD25. In particular, the present disclosure provides sequences of anti-human CD25 antibodies, which do not block the binding of CD25 to IL-2 or IL-2 signalling. Antibodies and antigen-binding portions thereof including such sequences can be used in pharmaceutical composition and methods of treatment, in particular for treating cancer.Type: GrantFiled: February 5, 2020Date of Patent: October 31, 2023Assignees: Tusk Therapeutics Ltd., Cancer Research Technology LimitedInventors: Anne Goubier, Beatriz Goyenechea Corzo, Josephine Salimu, Kevin Moulder, Pascal Merchiers, Mark Brown, Sergio Quezada, James Geoghegan, Bianka Prinz
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Patent number: 11787866Abstract: The present disclosure provides antibody sequences found in antibodies that bind to human CD25. In particular, the present disclosure provides sequences of anti-human CD25 antibodies, which do not block the binding of CD25 to IL-2 or IL-2 signalling. Antibodies and antigen-binding portions thereof including such sequences can be used in pharmaceutical composition and methods of treatment, in particular for treating cancer.Type: GrantFiled: February 5, 2020Date of Patent: October 17, 2023Assignees: Tusk Therapeutics Ltd., Cancer Research Technology LimitedInventors: Anne Goubier, Beatriz Goyenechea Corzo, Josephine Salimu, Kevin Moulder, Pascal Merchiers, Mark Brown, Sergio Quezada, James Geoghegan, Bianka Prinz
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Patent number: 11736542Abstract: Examples can include a system for video chat cycles within a social media application. An organizer platform can be used to design a schedule for the video chat cycles. This can include scheduled organizer content before, after, and between video chats. The organizer content can include graphics, video, and even live streams by the organizer.Type: GrantFiled: April 19, 2022Date of Patent: August 22, 2023Assignee: Lynk Technology Holdings, Inc.Inventors: Jeff Emile, Mark Brown
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Patent number: 11718817Abstract: Devices and methods for the efficient disaggregation of tissue samples, separating the tissue into individual intact cells or small aggregates of cells for analysis. A device may include a chamber to receive fluid and a tissue specimen containing more than one cell to be disaggregated. The chamber may include an opening and an agitator in fluid contact with the fluid and the tissue specimen. The agitator may include a micromotor which provides rotational motion to a shaft and an impeller fixed to the shaft such that the impeller and the shaft rotate together upon provision of the rotational motion by the micromotor. The device may include an electrical energy source electrically coupled to the micromotor to rotate the impeller sufficient to disaggregate the one or more individual cells from the tissue specimen and in a manner which does not lyse the one or more individual cells.Type: GrantFiled: March 28, 2022Date of Patent: August 8, 2023Assignee: CLAREMONT BIOSOLUTIONS LLCInventors: Mark Brown, Robert Doebler, Gary Fife Blackburn
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Patent number: 11707396Abstract: An apparatus for mounting and securing medical/surgical devices may be attached to a litter (40), The medical/surgical devices may include. for example, IV holders (186), aspirators (144). cardiac monitors (148) , defibrillators (150) , infusion pumps 152 (152), ventilators (146) and other devices. The apparatus frame assembly (10) includes rails (12), (14), (16), (18), (20), (46), (48), (50), (52) having cross-sections of standard surgical rails, for attachment of slidable rail clamps (84), (104). Medical device mounts (108), (110), (112) are attached to the slidable rail clamps. The medical device mounts have height and/or rotational adjustment to improve patient access and view. The apparatus may be mounted longitudinally anywhere along the litter to maximize access to the patient.Type: GrantFiled: March 3, 2021Date of Patent: July 25, 2023Assignee: The Government of the United States, as Represented by the Secretary of the ArmyInventors: Mark Brown, Scott Walters, Mark Easterday, Jay Bartlett, Jaime Lee