Abstract: Disclosed herein are methods of identifying a compound for treating or preventing an infection with an infectious microbe, such as a coronavirus, in a subject in need thereof. Also disclosed herein are compounds and compositions identified by said methods, and methods of use thereof.

Abstract: The invention provides compositions including anti-tryptase antibodies and pharmaceutical compositions thereof, as well as methods of using the same.

Abstract: Systems and methods are described for generating record clusters. The methods comprise receiving a plurality of records from data sources and providing at least a subset of the records to a scoring model that determines scores for various pairings of the records, a score for a given pair of the records representing a probability that the given pair of records contain data elements about the same entity. The method further comprises generating a graph data structure that includes a plurality of nodes, individual nodes representing a different record from the records. The method also comprises assigning a different unique identifier to individual clusters of the final clusters and responding to a request for data regarding a given entity by providing aggregated data elements from those records of the records associated with a cluster of the final clusters having an identifier that represents the given entity.

Abstract: An example system includes a vehicle having a prime mover motively coupled to a drive line; a motor/generator selectively coupled to the drive line, and configured to selectively modulate power transfer between an electrical load and the drive line; a battery pack; a DC/DC converter electrically interposed between the motor/generator and the electrical load, and between the battery pack and the electrical load, the DC/DC converter comprising a DC/DC converter housing; and a covering tray positioned over a plurality of batteries of the battery pack, the covering tray comprising a connectivity layer configured to provide electrical connectivity to terminals of the plurality of batteries.

Abstract: The present disclosure provides for using multiple inertial measurement units (IMUs) to recognize particular user activity, such as particular types of exercises and repetitions of such exercises. The IMUs may be located in consumer products, such as smartwatches and earbuds. Each IMU may include an accelerometer and a gyroscope, each with three axes of measurement, for a total of 12 raw measurement streams. A training image includes a plurality of subplots or tiles, each depicting a separate data stream. The training image is then used to train a machine learning model to recognize IMU data as corresponding to a particular type of exercise.

Abstract: A computer-implemented method for processing and/or analyzing nucleic acid sequencing data comprises receiving a first data input and a second data input. The first data input comprises untargeted sequencing data generated from a first nucleic acid sample obtained from a subject. The second data input comprises target-specific sequencing data generated from a second nucleic acid sample obtained from the subject. Next, with the aid of a computer processor, the first data input and the second data input are combined to produce a combined data set. Next, an output derived from the combined data set is generated. The output is indicative of the presence or absence of one or more polymorphisms of the first nucleic acid sample and/or the second nucleic acid sample.

Abstract: A vehicle lighting assembly includes a primary lens and a light source on a first side of the primary lens. The light source is configured to emit light through the primary lens. A light blade is on an opposite, second side of the primary lens. A secondary lens covers a portion of the light blade. A vehicle lighting method includes emitting light from a light source, directing the light through a primary lens, directing the light from the primary lens through a light blade, and directing the light from the light blade through a secondary lens.

Abstract: A housing of a device comprises a screw boss that extends outwardly from a first base plate proximate to a corner of the housing. Additionally, the housing of the device includes a force dissipation member. The force dissipation member includes a central portion that is sized to detachably attach around the screw boss. The force dissipation member further includes at least two arms that extend outwardly from the central portion, wherein each arm of the at least two arms is attached to a different side of the two walls of the housing.

Abstract: Methods for detecting on-target and predicted off-target genome editing events by providing a multiplex PCR reaction mixture with an on-target oligonucleotide primer and one or more off-target oligonucleotide primers and then hybridizing the on-target oligonucleotide primer and the one or more off-target oligonucleotide primers to target nucleic acid sequences, followed by cleaving blocking groups from the primers and extending the primers.

Abstract: A method and apparatus for automatically generating a meeting summary is disclosed herein. Meeting audio is recorded and converted into a text-based transcript. Handwritten meeting notes are converted into notes text. The transcript and notes text are correlated to provide correlated meeting text. Meeting topics are determined from the correlated meeting text. A meeting summary is generated from the meeting topics.

Abstract: Techniques are generally described for fusing sensor data of different modalities using a transformer. In various examples, first sensor data may be received from a first sensor and second sensor data may be received from a second sensor. A first feature representation of the first sensor data may be generated using a first machine learning model and a second feature representation of the second sensor data may be generated using a second machine learning model. In some examples, a modified first feature representation of the first sensor data may be generated based at least in part on a self-attention mechanism of a transformer encoder. The modified first feature representation may be generated based at least in part on the first feature representation and the second feature representation. A computer vision task may be performed using the modified first feature representation.

Abstract: Disclosed herein are methods, systems, and computer-readable media for generating an image corresponding to a text input. In an embodiment, operations may include accessing a text description and inputting the text description into a text encoder. The operations may include receiving, from the text encoder, a text embedding, and inputting at least one of the text description or the text embedding into a first sub-model configured to generate, based on at least one of the text description or the text embedding, a corresponding image embedding. The operations may include inputting at least one of the text description or the corresponding image embedding, generated by the first sub-model, into a second sub-model configured to generate, based on at least one of the text description or the corresponding image embedding, an output image. The operations may include making the output image, generated by the first second sub-model, accessible to a device.

Abstract: Provided herein are polypeptides that bind to a transferrin receptor, methods of generating such polypeptides, and methods of using the polypeptides to target a composition to a transferrin receptor-expressing cell.

Abstract: The present invention provides EBNA1 inhibitors, and/or pharmaceutical compositions comprising the same, that are useful for the treatment of diseases caused by EBNA1 activity, such as, but not limited to, cancer, infectious mononucleosis, chronic fatigue syndrome, multiple sclerosis, systemic lupus erythematosus and/or rheumatoid arthritis. The present invention further provides EBNA1 inhibitors, and/or pharmaceutical compositions comprising the same, that are useful for the treatment of diseases caused by latent Epstein-Barr Virus (EBV) infection and/or lytic EBV infection.

Abstract: Disclosed herein are methods, systems, and computer-readable media for generating computer code based on natural language input. In an embodiment, a method may comprise one or more of: receiving a docstring representing natural language text specifying a digital programming result; generating, using a trained machine learning model, and based on the docstring, a computer code sample configured to produce respective candidate results; causing the computer code sample to be executed; identifying, based on the executing, a computer code sample configured to produce a particular candidate result associated with the digital programming result; performing at least one of outputting, via a user interface, the identified computer code sample, compiling the identified computer code sample, transmitting the identified computer code sample to a recipient device, storing the identified computer code sample, and/or re-executing the identified computer code sample.

Abstract: Disclosed herein are methods, systems, and computer-readable media for generating natural language based on computer code input. In an embodiment, a method may comprise one or more of: accessing a docstring generation model configured to generate docstrings from computer code; receiving one or more computer code samples; generating, using the docstring generation model and based on the received one or more computer code samples, one or more candidate docstrings representing natural language text, each of the one or more candidate docstrings being associated with at least a portion of the one or more computer code samples; identifying at least one of the one or more candidate docstrings that provides an intent of the at least a portion of the one or more computer code samples; and/or outputting, via a user interface, the at least one identified docstring with the at least a portion of the one or more computer code samples.

Abstract: An article of manufacture includes instructions that, when loaded and executed by a processor, configure the processor to, at a coordinator electronic device, initiate a round of electronic device resource requests from a plurality of electronic devices, receive a request for an electronic device resource from each of the electronic devices, provide a fair access scheme for access to the electronic device resource for each of the electronic devices, and provide a proof to each of the electronic devices that the fair access scheme was used in providing access to the electronic device during the round.

Abstract: Proxied cross-ledger authentication techniques are disclosed. In various embodiments, a verifier presentation requirement is determined, the verifier presentation requirement indicating a set of elements required to be provided by a client to authenticate the client. An authentication contract instance is created on a market maker ledger not associated specifically with the verifier, the authentication contract instance including at least a subset of the elements required by the verifier presentation requirement. A verifier system associated with the verifier presentation requirement is configured to read information from the authentication contract instance, obtain from an issuer associated with the client an issuer revocation data associated with the authentication contract instance, and use the information read from the authentication contract instance and the issuer revocation data to authenticate the client.

Abstract: Devices and techniques for accelerated packet processing are described herein. The device can match an action to a portion of a network data packet and accelerate the packet-processing pipeline for the network data packet through the machine by processing the action.

Abstract: Proxied cross-ledger authentication techniques are disclosed. In various embodiments, a verifier presentation requirement is determined, the verifier presentation requirement indicating a set of elements required to be provided by a client to authenticate the client. An authentication contract instance is created on a market maker ledger not associated specifically with the verifier, the authentication contract instance including at least a subset of the elements required by the verifier presentation requirement. A verifier system associated with the verifier presentation requirement is configured to read information from the authentication contract instance, obtain from an issuer associated with the client an issuer revocation data associated with the authentication contract instance, and use the information read from the authentication contract instance and the issuer revocation data to authenticate the client.